2jdl - Revision history

OCA at 14:44, 13 December 2023

2023-12-13T14:44:11Z

← Older revision		Revision as of 14:44, 13 December 2023
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	<StructureSection load='2jdl' size='340' side='right'caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2jdl' size='340' side='right'caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Chinese_cucumber Chinese cucumber~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JDL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]]~~, [[~~1mrj~~\|~~1mrj~~]]~~, [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2~~.22 3.2.2.22] </span>~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [https://pdbe.org/2jdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [https://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [https://pdbe.org/2jdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [https://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/RIPT_TRIKI RIPT_TRIKI] Inactivates eukaryotic 60S ribosomal subunits.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Ribosomal protein P2\|Ribosomal protein P2]]		*[[Ribosomal protein P2\|Ribosomal protein P2]]
			*[[Ribosome inactivating protein 3D structures\|Ribosome inactivating protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Chinese cucumber~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~RRNA N-glycosylase~~]]		[[Category: Trichosanthes kirilowii]]
	[[Category: Au~~, S W~~]]		[[Category: Au SW]]
	[[Category: Mak~~, A N~~]]		[[Category: Mak AN]]
	[[Category: Shaw~~, P C~~]]		[[Category: Shaw PC]]
	[[Category: Too~~, P H~~]]		[[Category: Too PH]]
	[[Category: Wong~~, K B~~]]		[[Category: Wong KB]]
	[[Category: Zhu, G]]		[[Category: Zhu G]]
	~~[[Category: Antiviral protein]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Plant defense]]~~
	~~[[Category: Protein synthesis inhibitor]]~~
	~~[[Category: Ribosomal protein]]~~
	~~[[Category: Ribosome inactiviating protein]]~~
	~~[[Category: Toxin~~]]

OCA at 08:07, 19 January 2022

2022-01-19T08:07:59Z

← Older revision		Revision as of 08:07, 19 January 2022
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	<StructureSection load='2jdl' size='340' side='right'caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2jdl' size='340' side='right'caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2JDL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [~~http~~://pdbe.org/2jdl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [https://pdbe.org/2jdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [https://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:48, 15 April 2020

2020-04-15T07:48:15Z

← Older revision		Revision as of 07:48, 15 April 2020
Line 1:		Line 1:

	==Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin==		==Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin==
	<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2jdl' size='340' side='right'caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2JDL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://pdbe.org/2jdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://pdbe.org/2jdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Chinese cucumber]]		[[Category: Chinese cucumber]]
			[[Category: Large Structures]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
	[[Category: Au, S W]]		[[Category: Au, S W]]

OCA at 07:07, 11 July 2018

2018-07-11T07:07:25Z

← Older revision		Revision as of 07:07, 11 July 2018
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	==~~STRUCTURE OF~~ C-~~TERMINAL REGION OF ACIDIC~~ P2 ~~RIBOSOMAL PROTEIN COMPLEXED WITH TRICHOSANTHIN~~==
			==Structure of C-terminal region of acidic P2 ribosomal protein complexed with trichosanthin==
	<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://pdbe.org/2jdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://pdbe.org/2jdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2jdl ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jd/2jdl_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jd/2jdl_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 00:20, 10 February 2016

2016-02-10T00:20:55Z

← Older revision		Revision as of 00:20, 10 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jdl ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:30, 11 September 2015

2015-09-11T03:30:13Z

← Older revision		Revision as of 03:30, 11 September 2015
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	<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Trichosanthes_kirilowii Trichosanthes kirilowii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JDL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_cucumber Chinese cucumber]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://pdbe.org/2jdl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2jdl" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Trichosanthes kirilowii~~]]		[[Category: Chinese cucumber]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
	[[Category: Au, S W]]		[[Category: Au, S W]]

OCA at 16:59, 19 January 2015

2015-01-19T16:59:46Z

← Older revision		Revision as of 16:59, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JDL FirstGlance]. <br>		<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: Trichosanthes kirilowii]]		[[Category: Trichosanthes kirilowii]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
	[[Category: Au, S W.]]		[[Category: Au, S W]]
	[[Category: Mak, A N.]]		[[Category: Mak, A N]]
	[[Category: Shaw, P C.]]		[[Category: Shaw, P C]]
	[[Category: Too, P H.]]		[[Category: Too, P H]]
	[[Category: Wong, K B.]]		[[Category: Wong, K B]]
	[[Category: Zhu, G.]]		[[Category: Zhu, G]]
	[[Category: Antiviral protein]]		[[Category: Antiviral protein]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:07, 30 September 2014

2014-09-30T10:07:52Z

← Older revision		Revision as of 10:07, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2jdl~~.~~png~~\|~~left~~\|~~200px~~]]		==STRUCTURE OF C-TERMINAL REGION OF ACIDIC P2 RIBOSOMAL PROTEIN COMPLEXED WITH TRICHOSANTHIN==
			<StructureSection load='2jdl' size='340' side='right' caption='[[2jdl]], [[Resolution\|resolution]] 2.20Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JDL FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gis\|1gis]], [[1giu\|1giu]], [[1j4g\|1j4g]], [[1mrj\|1mrj]], [[1mrk\|1mrk]], [[1nli\|1nli]], [[1qd2\|1qd2]], [[1tcs\|1tcs]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jdl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jdl RCSB], [http://www.ebi.ac.uk/pdbsum/2jdl PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jd/2jdl_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Ribosome-inactivating proteins (RIPs) inhibit protein synthesis by enzymatically depurinating a specific adenine residue at the sarcin-ricin loop of the 28S rRNA, which thereby prevents the binding of elongation factors to the GTPase activation centre of the ribosome. Here, we present the 2.2 A crystal structure of trichosanthin (TCS) complexed to the peptide SDDDMGFGLFD, which corresponds to the conserved C-terminal elongation factor binding domain of the ribosomal P protein. The N-terminal region of this peptide interacts with Lys173, Arg174 and Lys177 in TCS, while the C-terminal region is inserted into a hydrophobic pocket. The interaction with the P protein contributes to the ribosome-inactivating activity of TCS. This 11-mer C-terminal P peptide can be docked with selected important plant and bacterial RIPs, indicating that a similar interaction may also occur with other RIPs.

	~~{{STRUCTURE_2jdl\| PDB=2jdl \| SCENE= }}~~		The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome.,Too PH, Ma MK, Mak AN, Wong YT, Tung CK, Zhu G, Au SW, Wong KB, Shaw PC Nucleic Acids Res. 2009 Feb;37(2):602-10. Epub 2008 Dec 10. PMID:19073700<ref>PMID:19073700</ref>

	~~===STRUCTURE OF C-TERMINAL REGION OF ACIDIC P2 RIBOSOMAL PROTEIN COMPLEXED WITH TRICHOSANTHIN===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_19073700}}~~		==See Also==
			*[[Ribosomal protein P2\|Ribosomal protein P2]]
	==~~About this Structure~~==		== References ==
	[[~~2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii~~]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA~~].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:019073700<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Trichosanthes kirilowii]]		[[Category: Trichosanthes kirilowii]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA: Protected "2jdl" [edit=sysop:move=sysop]

2013-01-07T14:36:11Z

Protected "2jdl" [edit=sysop:move=sysop]

← Older revision	Revision as of 14:36, 7 January 2013
(No difference)

OCA at 14:36, 7 January 2013

2013-01-07T14:36:08Z

← Older revision		Revision as of 14:36, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2jdl.png\|left\|200px]]		[[Image:2jdl.png\|left\|200px]]

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	{{STRUCTURE_2jdl\| PDB=2jdl \| SCENE= }}		{{STRUCTURE_2jdl\| PDB=2jdl \| SCENE= }}

	===STRUCTURE OF C-TERMINAL REGION OF ACIDIC P2 RIBOSOMAL PROTEIN COMPLEXED WITH TRICHOSANTHIN===		===STRUCTURE OF C-TERMINAL REGION OF ACIDIC P2 RIBOSOMAL PROTEIN COMPLEXED WITH TRICHOSANTHIN===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_19073700}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 19073700 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_19073700}}		{{ABSTRACT_PUBMED_19073700}}

	==About this Structure==		==About this Structure==
	~~2JDL~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA].		[[2jdl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_kirilowii Trichosanthes kirilowii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JDL OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19073700~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019073700</ref><references group="xtra"/>
	[[Category: Trichosanthes kirilowii]]		[[Category: Trichosanthes kirilowii]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
Line 39:		Line 27:
	[[Category: Ribosome inactiviating protein]]		[[Category: Ribosome inactiviating protein]]
	[[Category: Toxin]]		[[Category: Toxin]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 15 08:44:35 2009''~~