2la0 - Revision history

OCA at 08:16, 30 October 2024

2024-10-30T08:16:41Z

← Older revision		Revision as of 08:16, 30 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [https://pdbe.org/2la0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [https://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [https://pdbe.org/2la0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [https://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>

OCA at 09:32, 6 December 2023

2023-12-06T09:32:33Z

← Older revision		Revision as of 09:32, 6 December 2023
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	==Trn- peptide of the two-component bacteriocin Thuricin CD==		==Trn- peptide of the two-component bacteriocin Thuricin CD==
	<StructureSection load='2la0' size='340' side='right'caption='[[2la0~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2la0' size='340' side='right'caption='[[2la0]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=DTY:D-TYROSINE'>DTY</scene~~></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[2l9x\|2l9x]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [https://pdbe.org/2la0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [https://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [https://pdbe.org/2la0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [https://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>
	</table>		</table>
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	[[Category: Bacillus cereus 95/8201]]		[[Category: Bacillus cereus 95/8201]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hill, C]]		[[Category: Hill C]]
	[[Category: Mckay~~, R T~~]]		[[Category: Mckay RT]]
	[[Category: Ross~~, R P~~]]		[[Category: Ross RP]]
	[[Category: Sit~~, C S~~]]		[[Category: Sit CS]]
	[[Category: Vederas~~, J C]]~~		[[Category: Vederas JC]]
	~~[[Category: Antimicrobial protein]]~~
	~~[[Category: Crosslinked]]~~
	~~[[Category: Helical loop]]~~
	~~[[Category: Post-translationally modified]]~~
	~~[[Category: Thioether bridge~~]]

OCA at 07:49, 2 March 2022

2022-03-02T07:49:11Z

← Older revision		Revision as of 07:49, 2 March 2022
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	<StructureSection load='2la0' size='340' side='right'caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2la0' size='340' side='right'caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2l9x\|2l9x]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [~~http~~://pdbe.org/2la0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [https://pdbe.org/2la0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [https://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:55, 27 May 2020

2020-05-27T07:55:56Z

← Older revision		Revision as of 07:55, 27 May 2020
Line 1:		Line 1:

	==Trn- peptide of the two-component bacteriocin Thuricin CD==		==Trn- peptide of the two-component bacteriocin Thuricin CD==
	<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2la0' size='340' side='right'caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://pdbe.org/2la0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://pdbe.org/2la0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus cereus 95/8201]]		[[Category: Bacillus cereus 95/8201]]
			[[Category: Large Structures]]
	[[Category: Hill, C]]		[[Category: Hill, C]]
	[[Category: Mckay, R T]]		[[Category: Mckay, R T]]

OCA at 19:33, 1 August 2018

2018-08-01T19:33:12Z

← Older revision		Revision as of 19:33, 1 August 2018
Line 1:		Line 1:

	==Trn- peptide of the two-component bacteriocin Thuricin CD==		==Trn- peptide of the two-component bacteriocin Thuricin CD==
	<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
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	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://pdbe.org/2la0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://pdbe.org/2la0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2la0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:45, 9 September 2015

2015-09-09T20:45:12Z

← Older revision		Revision as of 20:45, 9 September 2015
Line 5:		Line 5:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://pdbe.org/2la0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2la0" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:12, 22 December 2014

2014-12-22T05:12:46Z

← Older revision		Revision as of 05:12, 22 December 2014
Line 2:		Line 2:
	<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LA0 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>
	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>
	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>		</table>
	<table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 13:
	The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to alpha-carbon cross-links.,Sit CS, McKay RT, Hill C, Ross RP, Vederas JC J Am Chem Soc. 2011 May 25;133(20):7680-3. Epub 2011 Apr 28. PMID:21526839<ref>PMID:21526839</ref>		The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to alpha-carbon cross-links.,Sit CS, McKay RT, Hill C, Ross RP, Vederas JC J Am Chem Soc. 2011 May 25;133(20):7680-3. Epub 2011 Apr 28. PMID:21526839<ref>PMID:21526839</ref>

	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus cereus 95/8201]]		[[Category: Bacillus cereus 95/8201]]
	[[Category: Hill, C.]]		[[Category: Hill, C]]
	[[Category: Mckay, R T.]]		[[Category: Mckay, R T]]
	[[Category: Ross, R P.]]		[[Category: Ross, R P]]
	[[Category: Sit, C S.]]		[[Category: Sit, C S]]
	[[Category: Vederas, J C.]]		[[Category: Vederas, J C]]
	[[Category: Antimicrobial protein]]		[[Category: Antimicrobial protein]]
	[[Category: Crosslinked]]		[[Category: Crosslinked]]

OCA at 09:53, 1 May 2014

2014-05-01T09:53:50Z

← Older revision		Revision as of 09:53, 1 May 2014
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	<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>		<table><tr><td colspan='2'>[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>
	<b>[[Non-Standard_Residue\|NonStd Res:]]</b> <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene></td></tr>
	<b>[[Related_structure\|Related:]]</b> [[2l9x\|2l9x]]<br>		<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2l9x\|2l9x]]</td></tr>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span><br>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Thuricin CD is an antimicrobial factor that consists of two peptides, Trn-alpha and Trn-beta, that exhibit synergistic activity against drug resistant strains of Clostridium difficile. Trn-alpha and Trn-beta each possess three sulfur to alpha-carbon thioether bridges for which the stereochemistry is unknown. This report presents the three-dimensional solution structures of Trn-alpha and Trn-beta. Structure calculations were performed for the eight possible stereoisomers of each peptide based on the same NMR data. The structure of the stereoisomer that best fit the experimental data was chosen as the representative structure for each peptide. It was determined that Trn-alpha has L-stereochemistry at Ser21 (alpha-R), L-stereochemistry at Thr25 (alpha-R), and D-stereochemistry at Thr28 (alpha-S) (an LLD isomer). Trn-beta was also found to be the LLD isomer, with L-stereochemistry at Thr21 (alpha-R), L-stereochemistry at Ala25 (alpha-R), and D-stereochemistry at Tyr28 (alpha-S).		Thuricin CD is an antimicrobial factor that consists of two peptides, Trn-alpha and Trn-beta, that exhibit synergistic activity against drug resistant strains of Clostridium difficile. Trn-alpha and Trn-beta each possess three sulfur to alpha-carbon thioether bridges for which the stereochemistry is unknown. This report presents the three-dimensional solution structures of Trn-alpha and Trn-beta. Structure calculations were performed for the eight possible stereoisomers of each peptide based on the same NMR data. The structure of the stereoisomer that best fit the experimental data was chosen as the representative structure for each peptide. It was determined that Trn-alpha has L-stereochemistry at Ser21 (alpha-R), L-stereochemistry at Thr25 (alpha-R), and D-stereochemistry at Thr28 (alpha-S) (an LLD isomer). Trn-beta was also found to be the LLD isomer, with L-stereochemistry at Thr21 (alpha-R), L-stereochemistry at Ala25 (alpha-R), and D-stereochemistry at Tyr28 (alpha-S).
Line 13:		Line 15:

	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
			</div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:18, 30 April 2014

2014-04-30T10:18:27Z

← Older revision		Revision as of 10:18, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>		[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>
	<b>Related:</b> [[2l9x\|2l9x]]<br>		<b>[[Non-Standard_Residue\|NonStd Res:]]</b> <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene><br>
			<b>[[Related_structure\|Related:]]</b> [[2l9x\|2l9x]]<br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
			<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2la0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2la0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2la0 RCSB], [http://www.ebi.ac.uk/pdbsum/2la0 PDBsum]</span><br>
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
	Thuricin CD is an antimicrobial factor that consists of two peptides, Trn-alpha and Trn-beta, that exhibit synergistic activity against drug resistant strains of Clostridium difficile. Trn-alpha and Trn-beta each possess three sulfur to alpha-carbon thioether bridges for which the stereochemistry is unknown. This report presents the three-dimensional solution structures of Trn-alpha and Trn-beta. Structure calculations were performed for the eight possible stereoisomers of each peptide based on the same NMR data. The structure of the stereoisomer that best fit the experimental data was chosen as the representative structure for each peptide. It was determined that Trn-alpha has L-stereochemistry at Ser21 (alpha-R), L-stereochemistry at Thr25 (alpha-R), and D-stereochemistry at Thr28 (alpha-S) (an LLD isomer). Trn-beta was also found to be the LLD isomer, with L-stereochemistry at Thr21 (alpha-R), L-stereochemistry at Ala25 (alpha-R), and D-stereochemistry at Tyr28 (alpha-S).		Thuricin CD is an antimicrobial factor that consists of two peptides, Trn-alpha and Trn-beta, that exhibit synergistic activity against drug resistant strains of Clostridium difficile. Trn-alpha and Trn-beta each possess three sulfur to alpha-carbon thioether bridges for which the stereochemistry is unknown. This report presents the three-dimensional solution structures of Trn-alpha and Trn-beta. Structure calculations were performed for the eight possible stereoisomers of each peptide based on the same NMR data. The structure of the stereoisomer that best fit the experimental data was chosen as the representative structure for each peptide. It was determined that Trn-alpha has L-stereochemistry at Ser21 (alpha-R), L-stereochemistry at Thr25 (alpha-R), and D-stereochemistry at Thr28 (alpha-S) (an LLD isomer). Trn-beta was also found to be the LLD isomer, with L-stereochemistry at Thr21 (alpha-R), L-stereochemistry at Ala25 (alpha-R), and D-stereochemistry at Tyr28 (alpha-S).

OCA at 08:36, 30 April 2014

2014-04-30T08:36:40Z

← Older revision		Revision as of 08:36, 30 April 2014
Line 1:		Line 1:
	[[~~Image~~:~~2la0~~.~~png~~\|~~left\|200px~~]]		==Trn- peptide of the two-component bacteriocin Thuricin CD==
			<StructureSection load='2la0' size='340' side='right' caption='[[2la0]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
			== Structural highlights ==
			[[2la0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus_95/8201 Bacillus cereus 95/8201]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA]. <br>
			<b>Related:</b> [[2l9x\|2l9x]]<br>
			<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
			== Publication Abstract from PubMed ==
			Thuricin CD is an antimicrobial factor that consists of two peptides, Trn-alpha and Trn-beta, that exhibit synergistic activity against drug resistant strains of Clostridium difficile. Trn-alpha and Trn-beta each possess three sulfur to alpha-carbon thioether bridges for which the stereochemistry is unknown. This report presents the three-dimensional solution structures of Trn-alpha and Trn-beta. Structure calculations were performed for the eight possible stereoisomers of each peptide based on the same NMR data. The structure of the stereoisomer that best fit the experimental data was chosen as the representative structure for each peptide. It was determined that Trn-alpha has L-stereochemistry at Ser21 (alpha-R), L-stereochemistry at Thr25 (alpha-R), and D-stereochemistry at Thr28 (alpha-S) (an LLD isomer). Trn-beta was also found to be the LLD isomer, with L-stereochemistry at Thr21 (alpha-R), L-stereochemistry at Ala25 (alpha-R), and D-stereochemistry at Tyr28 (alpha-S).

	<!--		The 3D structure of thuricin CD, a two-component bacteriocin with cysteine sulfur to alpha-carbon cross-links.,Sit CS, McKay RT, Hill C, Ross RP, Vederas JC J Am Chem Soc. 2011 May 25;133(20):7680-3. Epub 2011 Apr 28. PMID:21526839<ref>PMID:21526839</ref>
	~~The line below this paragraph~~, ~~containing "STRUCTURE_2la0"~~, ~~creates the "Structure Box" on the page~~.
	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display~~.
	-->
	~~{{STRUCTURE_2la0\| PDB=2la0 \| SCENE= }}~~

	~~===Trn- peptide~~ of the ~~two-component bacteriocin Thuricin CD===~~		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
			== References ==
			<references/>
	~~<!--~~		__TOC__
	~~The line below this paragraph, {{ABSTRACT_PUBMED_21526839}}, adds the Publication Abstract to the page~~		</StructureSection>
	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21526839 is the PubMed ID number~~.		[[Category: Bacillus cereus 95/8201]]
	-->
	~~{{ABSTRACT_PUBMED_21526839}}~~

	==~~About this Structure~~==
	~~[[2la0]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Bacteria Bacteria]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LA0 OCA].~~

	~~==Reference==~~
	<~~ref group="xtra">PMID:021526839</ref><references group="xtra"~~/>
	[[Category: ~~Bacteria~~]]
	[[Category: Hill, C.]]		[[Category: Hill, C.]]
	[[Category: Mckay, R T.]]		[[Category: Mckay, R T.]]