2lap - Revision history

OCA at 05:40, 15 May 2024

2024-05-15T05:40:48Z

← Older revision		Revision as of 05:40, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [https://pdbe.org/2lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [https://www.ebi.ac.uk/pdbsum/2lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [https://pdbe.org/2lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [https://www.ebi.ac.uk/pdbsum/2lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:29, 18 January 2023

2023-01-18T08:29:15Z

← Older revision		Revision as of 08:29, 18 January 2023
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	==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==		==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==
	<StructureSection load='2lap' size='340' side='right'caption='[[2lap~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>		<StructureSection load='2lap' size='340' side='right'caption='[[2lap]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [https://pdbe.org/2lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [https://www.ebi.ac.uk/pdbsum/2lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [https://pdbe.org/2lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [https://www.ebi.ac.uk/pdbsum/2lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN]] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>		[https://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Ames, J]]		[[Category: Ames J]]
	~~[[Category: Ef-hand]]~~
	~~[[Category: Metal binding protein~~]]

OCA at 07:39, 14 April 2021

2021-04-14T07:39:24Z

← Older revision		Revision as of 07:39, 14 April 2021
Line 1:		Line 1:

	==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==		==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==
	<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2lap' size='340' side='right'caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LAP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LAP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [~~http~~://pdbe.org/2lap PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lap PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [https://pdbe.org/2lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [https://www.ebi.ac.uk/pdbsum/2lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN]] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>		[[https://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN]] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>
	== References ==		== References ==
	<references/>		<references/>
Line 15:		Line 15:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Ames, J]]		[[Category: Ames, J]]
	[[Category: Ef-hand]]		[[Category: Ef-hand]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 19:24, 1 August 2018

2018-08-01T19:24:35Z

← Older revision		Revision as of 19:24, 1 August 2018
Line 1:		Line 1:

	==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==		==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==
	<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://pdbe.org/2lap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://pdbe.org/2lap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lap ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 14:45, 10 September 2015

2015-09-10T14:45:04Z

← Older revision		Revision as of 14:45, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LAP FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LAP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://pdbe.org/2lap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 13:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Ames, J]]		[[Category: Ames, J]]
	[[Category: Ef-hand]]		[[Category: Ef-hand]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 01:41, 25 December 2014

2014-12-25T01:41:49Z

← Older revision		Revision as of 01:41, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CABP1_HUMAN CABP1_HUMAN]] Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).<ref>PMID:11865310</ref> <ref>PMID:14570872</ref> <ref>PMID:15140941</ref> <ref>PMID:15980432</ref> <ref>PMID:15895247</ref>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 04:58, 22 December 2014

2014-12-22T04:58:38Z

← Older revision		Revision as of 04:58, 22 December 2014
Line 2:		Line 2:
	<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LAP FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>
	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>		</table>
	<table>
	~~== References ==~~
	~~<references/~~>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Ames, J.]]		[[Category: Ames, J]]
	[[Category: Ef-hand]]		[[Category: Ef-hand]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 09:46, 1 May 2014

2014-05-01T09:46:22Z

← Older revision		Revision as of 09:46, 1 May 2014
Line 2:		Line 2:
	<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>		<table><tr><td colspan='2'>[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>
	<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CABP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
	<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span><br>		<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span></td></tr>
			<table>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:08, 30 April 2014

2014-04-30T10:08:41Z

← Older revision		Revision as of 10:08, 30 April 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>		[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>
			<b>[[Ligand\|Ligands:]]</b> <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
	<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
			<b>Resources:</b> <span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lap RCSB], [http://www.ebi.ac.uk/pdbsum/2lap PDBsum]</span><br>
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:29, 30 April 2014

2014-04-30T08:29:45Z

← Older revision		Revision as of 08:29, 30 April 2014
Line 1:		Line 1:
	~~[[Image:2lap.jpg\|left\|200px]]~~		==NMR structure of Ca2+-bound CaBP1 C-domain with RDC==
			<StructureSection load='2lap' size='340' side='right' caption='[[2lap]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	~~<!--~~		== Structural highlights ==
	~~The line below this paragraph, containing "STRUCTURE_2lap", creates the "Structure Box" on the page.~~		[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA]. <br>
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~		<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~		== References ==
	~~or leave the SCENE parameter empty for the default display.~~		<references/>
	~~-->~~		__TOC__
	~~{{STRUCTURE_2lap\| PDB=2lap \| SCENE= }}~~		</StructureSection>

	===NMR structure of Ca2+-bound CaBP1 C-domain with RDC===


	==~~About this Structure~~==
	[[2lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LAP OCA].
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Ames, J.]]		[[Category: Ames, J.]]
	[[Category: Ef-hand]]		[[Category: Ef-hand]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]