2lez - Revision history

OCA at 06:55, 1 May 2024

2024-05-01T06:55:24Z

← Older revision		Revision as of 06:55, 1 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 10:55, 15 February 2023

2023-02-15T10:55:45Z

← Older revision		Revision as of 10:55, 15 February 2023
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	==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==		==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
	<StructureSection load='2lez' size='340' side='right'caption='[[2lez~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2lez' size='340' side='right'caption='[[2lez]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>		[https://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Bacillus typhimurium loeffler 1892]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Arrowsmith, C]]		[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
	[[Category: Daniels, C]]		[[Category: Arrowsmith C]]
	[[Category: Garcia, M]]		[[Category: Daniels C]]
	[[Category: Houliston, S]]		[[Category: Garcia M]]
	[[Category: Lemak, A]]		[[Category: Houliston S]]
	[[Category: Montelione~~, G T]]~~		[[Category: Lemak A]]
	~~[[Category: Structural genomic~~]]		[[Category: Montelione GT]]
	[[Category: Savchenko, A]]		[[Category: Savchenko A]]
	[[Category: Yee, A]]		[[Category: Yee A]]
	~~[[Category: Bacterial effector]]~~
	~~[[Category: Nesg]]~~
	~~[[Category: Psi-biology]]~~
	~~[[Category: Signaling protein]]~~
	~~[[Category: Virulence factor~~]]

OCA at 10:09, 12 May 2021

2021-05-12T10:09:35Z

← Older revision		Revision as of 10:09, 12 May 2021
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	==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==		==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
	<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lez' size='340' side='right'caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [~~http~~://pdbe.org/2lez PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lez PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>		[[https://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus typhimurium loeffler 1892]]		[[Category: Bacillus typhimurium loeffler 1892]]
			[[Category: Large Structures]]
	[[Category: Arrowsmith, C]]		[[Category: Arrowsmith, C]]
	[[Category: Daniels, C]]		[[Category: Daniels, C]]

OCA at 19:58, 1 August 2018

2018-08-01T19:58:54Z

← Older revision		Revision as of 19:58, 1 August 2018
Line 1:		Line 1:

	==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==		==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
	<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://pdbe.org/2lez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://pdbe.org/2lez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	[[Category: Bacterial effector]]		[[Category: Bacterial effector]]
	[[Category: Nesg]]		[[Category: Nesg]]
			[[Category: Psi-biology]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	[[Category: Virulence factor]]		[[Category: Virulence factor]]

OCA at 19:36, 10 September 2015

2015-09-10T19:36:32Z

← Older revision		Revision as of 19:36, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar~~ typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 ~~Salmonella enterica subsp. enterica serovar Typhimurium~~])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://pdbe.org/2lez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Salmonella enterica subsp. enterica serovar~~ typhimurium]]		[[Category: Bacillus typhimurium loeffler 1892]]
	[[Category: Arrowsmith, C]]		[[Category: Arrowsmith, C]]
	[[Category: Daniels, C]]		[[Category: Daniels, C]]

OCA at 05:06, 25 December 2014

2014-12-25T05:06:52Z

← Older revision		Revision as of 05:06, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 05:56, 22 December 2014

2014-12-22T05:56:31Z

← Older revision		Revision as of 05:56, 22 December 2014
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	~~{{STRUCTURE_2lez\| PDB=2lez \| SCENE= }}~~		==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
	===Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a===		<StructureSection load='2lez' size='340' side='right' caption='[[2lez]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
			== Structural highlights ==
	==~~Function~~==		<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
	[[~~http://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY~~]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, ~~known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref~~>~~PMID:12864852~~<~~/ref~~> <~~ref~~>~~PMID:15987736~~<~~/ref> <ref>PMID:16938850</ref~~>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pipB2, STM2780 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 Salmonella enterica subsp. enterica serovar Typhimurium])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [http://www.ebi.ac.uk/pdbsum/2lez PDBsum]</span></td></tr>
	~~==About this Structure==~~		</table>
	[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA].		__TOC__
			</StructureSection>
	==~~Reference~~==
	<~~references group~~="~~xtra~~"/><~~references~~/>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Arrowsmith, C.]]		[[Category: Arrowsmith, C]]
	[[Category: Daniels, C.]]		[[Category: Daniels, C]]
	[[Category: Garcia, M.]]		[[Category: Garcia, M]]
	[[Category: Houliston, S.]]		[[Category: Houliston, S]]
	[[Category: Lemak, A.]]		[[Category: Lemak, A]]
	[[Category: Montelione, G T.]]		[[Category: Montelione, G T]]
	[[Category: ~~NESG, Northeast~~ Structural ~~Genomics Consortium.~~]]		[[Category: Structural genomic]]
	[[Category: Savchenko, A.]]		[[Category: Savchenko, A]]
	[[Category: Yee, A.]]		[[Category: Yee, A]]
	[[Category: Bacterial effector]]		[[Category: Bacterial effector]]
	[[Category: Nesg]]		[[Category: Nesg]]
	~~[[Category: Northeast structural genomics consortium]]~~
	[[Category: Signaling protein]]		[[Category: Signaling protein]]
	~~[[Category: Structural genomic]]~~
	[[Category: Virulence factor]]		[[Category: Virulence factor]]

OCA at 07:59, 16 May 2013

2013-05-16T07:59:07Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_2lez|  PDB=2lez  |  SCENE=  }}
-The entry 2lez is ON HOLD
+==Function==
-Authors: Lemak, A., Yee, A., Houliston, S., Garcia, M., Daniels, C., Savchenko, A., Arrowsmith, C., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
+==About this Structure==
-Description: Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a
+==Reference==

OCA at 06:38, 13 July 2011

2011-07-13T06:38:01Z

← Older revision		Revision as of 06:38, 13 July 2011
Line 3:		Line 3:
	The entry 2lez is ON HOLD		The entry 2lez is ON HOLD

	Authors: Lemak, A., Yee, A., Houliston, S., Garcia, M., Daniels, C., Savchenko, A., Arrowsmith, C.		Authors: Lemak, A., Yee, A., Houliston, S., Garcia, M., Daniels, C., Savchenko, A., Arrowsmith, C., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)

	Description: Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a		Description: Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a

OCA: Protected "2lez" [edit=sysop:move=sysop]

2011-07-06T18:12:42Z

Protected "2lez" [edit=sysop:move=sysop]

← Older revision	Revision as of 18:12, 6 July 2011
(No difference)