2lis - Revision history

OCA at 00:07, 28 December 2023

2023-12-28T00:07:54Z

← Older revision		Revision as of 00:07, 28 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~2lyn~~\|~~2lyn~~]]~~</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [https://pdbe.org/2lis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [https://www.ebi.ac.uk/pdbsum/2lis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [https://pdbe.org/2lis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [https://www.ebi.ac.uk/pdbsum/2lis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ELYS_HALRU ELYS_HALRU]] Dissolves the egg vitelline layer nonenzymatically during fertilization. It creates a hole of about 3 mu-m in diameter through which the sperm pass.		[https://www.uniprot.org/uniprot/ELYS_HALRU ELYS_HALRU] Dissolves the egg vitelline layer nonenzymatically during fertilization. It creates a hole of about 3 mu-m in diameter through which the sperm pass.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Lysin\|Lysin]]		*[[Lysin 3D structures\|Lysin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Haliotis rufescens]]		[[Category: Haliotis rufescens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kresge, N]]		[[Category: Kresge N]]
	[[Category: Stout~~, C D~~]]		[[Category: Stout CD]]
	[[Category: Vacquier~~, V D]]~~		[[Category: Vacquier VD]]
	~~[[Category: Abalone lysin]]~~
	~~[[Category: Cell adhesion]]~~
	~~[[Category: Fertilization protein]]~~
	~~[[Category: Gamete recognition protein~~]]

OCA at 07:52, 9 February 2022

2022-02-09T07:52:19Z

← Older revision		Revision as of 07:52, 9 February 2022
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	<StructureSection load='2lis' size='340' side='right'caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='2lis' size='340' side='right'caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lyn\|2lyn]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [~~http~~://pdbe.org/2lis PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lis PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [https://pdbe.org/2lis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [https://www.ebi.ac.uk/pdbsum/2lis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ELYS_HALRU ELYS_HALRU]] Dissolves the egg vitelline layer nonenzymatically during fertilization. It creates a hole of about 3 mu-m in diameter through which the sperm pass.		[[https://www.uniprot.org/uniprot/ELYS_HALRU ELYS_HALRU]] Dissolves the egg vitelline layer nonenzymatically during fertilization. It creates a hole of about 3 mu-m in diameter through which the sperm pass.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:05, 6 May 2020

2020-05-06T07:05:32Z

← Older revision		Revision as of 07:05, 6 May 2020
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	==HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER==		==HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER==
	<StructureSection load='2lis' size='340' side='right' caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='2lis' size='340' side='right'caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://pdbe.org/2lis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://pdbe.org/2lis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Haliotis rufescens]]		[[Category: Haliotis rufescens]]
			[[Category: Large Structures]]
	[[Category: Kresge, N]]		[[Category: Kresge, N]]
	[[Category: Stout, C D]]		[[Category: Stout, C D]]

OCA at 19:57, 1 August 2018

2018-08-01T19:57:01Z

← Older revision		Revision as of 19:57, 1 August 2018
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	==HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER==		==HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER==
	<StructureSection load='2lis' size='340' side='right' caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='2lis' size='340' side='right' caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>
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	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://pdbe.org/2lis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://pdbe.org/2lis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lis ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/li/2lis_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/li/2lis_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:06, 8 February 2016

2016-02-08T03:06:33Z

← Older revision		Revision as of 03:06, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2lis ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 2lis" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2lis" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Lysin\|Lysin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:16, 10 September 2015

2015-09-10T07:16:47Z

← Older revision		Revision as of 07:16, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://pdbe.org/2lis PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2lis" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:07, 24 December 2014

2014-12-24T20:07:56Z

← Older revision		Revision as of 20:07, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/ELYS_HALRU ELYS_HALRU]] Dissolves the egg vitelline layer nonenzymatically during fertilization. It creates a hole of about 3 mu-m in diameter through which the sperm pass.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Haliotis rufescens]]		[[Category: Haliotis rufescens]]
	[[Category: Kresge, N.]]		[[Category: Kresge, N]]
	[[Category: Stout, C D.]]		[[Category: Stout, C D]]
	[[Category: Vacquier, V D.]]		[[Category: Vacquier, V D]]
	[[Category: Abalone lysin]]		[[Category: Abalone lysin]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]
	[[Category: Fertilization protein]]		[[Category: Fertilization protein]]
	[[Category: Gamete recognition protein]]		[[Category: Gamete recognition protein]]

OCA at 18:24, 30 September 2014

2014-09-30T18:24:07Z

← Older revision		Revision as of 18:24, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2lis~~.~~png~~\|~~left~~\|~~200px~~]]		==HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER==
			<StructureSection load='2lis' size='340' side='right' caption='[[2lis]], [[Resolution\|resolution]] 1.35Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LIS FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lyn\|2lyn]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lis RCSB], [http://www.ebi.ac.uk/pdbsum/2lis PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/li/2lis_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Abalone sperm use lysin to make a hole in the egg's protective vitelline envelope (VE). When released from sperm, lysin first binds to the VE receptor for lysin (VERL) then dissolves the VE by a non-enzymatic mechanism. The structures of the monomeric and dimeric forms of Haliotis rufescens (red abalone) lysin, previously solved at 1.90 and 2.75 A, respectively, have now been refined to 1.35 and 2.07 A, respectively. The monomeric form of lysin was refined using previously obtained crystallization conditions, while the dimer was solved in a new crystal form with four molecules (two dimers) per asymmetric unit. These high-resolution structures reveal alternate residue conformations, enabling a thorough analysis of the conserved residues contributing to the amphipathic nature of lysin. The availability of five independent high-resolution copies of lysin permits comparisons leading to insights on the local flexibility of lysin and alternative conformations of the hypervariable N-terminus, thought to be involved in species-specific receptor recognition. The new analysis led to the discovery of the basic nature of a cleft formed upon dimerization and a patch of basic residues in the dimer interface. Identification of these features was not possible at lower resolution. In light of this new information, a model explaining the binding of sperm lysin to egg VERL and the subsequent dissolution of the egg VE is proposed.

	~~{{STRUCTURE_2lis\| PDB=2lis \| SCENE= }}~~		1.35 and 2.07 A resolution structures of the red abalone sperm lysin monomer and dimer reveal features involved in receptor binding.,Kresge N, Vacquier VD, Stout CD Acta Crystallogr D Biol Crystallogr. 2000 Jan;56(Pt 1):34-41. PMID:10666624<ref>PMID:10666624</ref>

	~~===HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_10666624}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2lis]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Haliotis_rufescens Haliotis rufescens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:010666624<~~/~~ref><ref group="xtra">PMID:014695246</ref~~><~~references group="xtra"~~/>
	[[Category: Haliotis rufescens]]		[[Category: Haliotis rufescens]]
	[[Category: Kresge, N.]]		[[Category: Kresge, N.]]

OCA: Protected "2lis" [edit=sysop:move=sysop]

2013-01-07T13:15:26Z

Protected "2lis" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:15, 7 January 2013
(No difference)

OCA at 13:15, 7 January 2013

2013-01-07T13:15:25Z

← Older revision		Revision as of 13:15, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2lis.png\|left\|200px]]		[[Image:2lis.png\|left\|200px]]

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	{{STRUCTURE_2lis\| PDB=2lis \| SCENE= }}		{{STRUCTURE_2lis\| PDB=2lis \| SCENE= }}

	===HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER===		===HIGH RESOLUTION STRUCTURE OF THE RED ABALONE LYSIN MONOMER===


	~~<!--~~
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	{{ABSTRACT_PUBMED_10666624}}		{{ABSTRACT_PUBMED_10666624}}

	==About this Structure==		==About this Structure==
	~~2LIS~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA].		[[2lis]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haliotis_rufescens Haliotis rufescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LIS OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~10666624~~</ref><references group="xtra"/>		<ref group="xtra">PMID:010666624</ref><ref group="xtra">PMID:014695246</ref><references group="xtra"/>
	[[Category: Haliotis rufescens]]		[[Category: Haliotis rufescens]]
	[[Category: Kresge, N.]]		[[Category: Kresge, N.]]
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	[[Category: Vacquier, V D.]]		[[Category: Vacquier, V D.]]
	[[Category: Abalone lysin]]		[[Category: Abalone lysin]]
			[[Category: Cell adhesion]]
	[[Category: Fertilization protein]]		[[Category: Fertilization protein]]
	[[Category: Gamete recognition protein]]		[[Category: Gamete recognition protein]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:21:18 2009''~~