2lsf - Revision history

OCA at 06:57, 1 May 2024

2024-05-01T06:57:07Z

@@ Line 8: / Line 8: @@
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [https://pdbe.org/2lsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [https://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>
 </table>
 __TOC__
 </StructureSection>

OCA at 12:18, 15 November 2023

2023-11-15T12:18:12Z

← Older revision		Revision as of 12:18, 15 November 2023
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	==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==		==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==
	<StructureSection load='2lsf' size='340' side='right'caption='[[2lsf~~]], [[NMR_Ensembles_of_Models \| 26 NMR models~~]]' scene=''>		<StructureSection load='2lsf' size='340' side='right'caption='[[2lsf]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [https://pdbe.org/2lsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [https://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [https://pdbe.org/2lsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [https://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Lukin, M]]		[[Category: Lukin M]]
	~~[[Category: Santos, C de los~~]]		[[Category: Zaliznyak T]]
	[[Category: Zaliznyak, T]]		[[Category: De los Santos C]]
	[[Category: ~~Dna]]~~
	~~[[Category: Ner~~]]

OCA at 07:54, 9 February 2022

2022-02-09T07:54:08Z

← Older revision		Revision as of 07:54, 9 February 2022
Line 3:		Line 3:
	<StructureSection load='2lsf' size='340' side='right'caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>		<StructureSection load='2lsf' size='340' side='right'caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [~~http~~://pdbe.org/2lsf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [https://pdbe.org/2lsf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [https://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:07, 6 May 2020

2020-05-06T07:07:49Z

← Older revision		Revision as of 07:07, 6 May 2020
Line 1:		Line 1:

	==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==		==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==
	<StructureSection load='2lsf' size='340' side='right' caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>		<StructureSection load='2lsf' size='340' side='right'caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://pdbe.org/2lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://pdbe.org/2lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Lukin, M]]		[[Category: Lukin, M]]
	[[Category: Santos, C de los]]		[[Category: Santos, C de los]]

OCA at 19:17, 1 August 2018

2018-08-01T19:17:33Z

← Older revision		Revision as of 19:17, 1 August 2018
Line 1:		Line 1:

	==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==		==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==
	<StructureSection load='2lsf' size='340' side='right' caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>		<StructureSection load='2lsf' size='340' side='right' caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://pdbe.org/2lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://pdbe.org/2lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lsf ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:24, 10 September 2015

2015-09-10T00:24:42Z

← Older revision		Revision as of 00:24, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://pdbe.org/2lsf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2lsf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:10, 19 January 2015

2015-01-19T13:10:45Z

← Older revision		Revision as of 13:10, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>
	<table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Lukin, M.]]		[[Category: Lukin, M]]
	[[Category: Santos, C de los.]]		[[Category: Santos, C de los]]
	[[Category: Zaliznyak, T.]]		[[Category: Zaliznyak, T]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Ner]]		[[Category: Ner]]

OCA at 04:23, 29 September 2014

2014-09-29T04:23:26Z

← Older revision		Revision as of 04:23, 29 September 2014
Line 1:		Line 1:
	[[~~Image~~:2lsf.~~png\|left\|200px~~]]		==Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER==
			<StructureSection load='2lsf' size='340' side='right' caption='[[2lsf]], [[NMR_Ensembles_of_Models \| 26 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LSF FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=02I:(6S,7S,8S,10R)-4-AMINO-8-HYDROXY-7,8,9,10-TETRAHYDRO-6H-7,10-EPOXYAZEPINO[1,2-E]PURIN-6-YL+DIHYDROGEN+PHOSPHATE'>02I</scene></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lsf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lsf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lsf RCSB], [http://www.ebi.ac.uk/pdbsum/2lsf PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Cellular respiration and ionizing radiation generate 5',8-cyclo-2'-deoxyribonucleosides, an especial type of DNA damage that involves two modifications in the same nucleotide. These lesions evade the action of base excision glycosylases and their removal is a function of the nucleotide excision repair pathway. Diastereomeric 5',8-cyclo-2'-deoxyadenosine block mammalian DNA replication, diminish the levels of DNA transcription and induce transcriptional mutagenesis. Using solution state NMR spectroscopy and restrained molecular dynamics simulations, we have determined the structure of an undecameric DNA duplex having a centrally located (5'S)-5',8-cyclo-2'-deoxyadenosine residue paired to T. The damaged duplex structure is a right-handed helix having Watson-Crick base-pair alignments throughout and 2-deoxyribose puckers within the B-form conformation. Only small structural perturbations are observed at the lesion-containing and 5'-flanking base-pair. The 2-deoxyribose of the damaged nucleotide adopts the O4'-exo conformation and the S-cdAT base-pair is propeller twisted. The 5'-lesion-flanking base is tilted forming a significantly buckled base-pair with its partner guanine. Analysis of UV-melting curves indicates mild thermal and thermodynamic destabilization on the damaged duplex. The S-cdAT duplex structure shows many similarities and some intriguing differences with the recently reported structure of an S-cdG*dC duplex(31) that suggest different lesion site dynamics.

	~~{{STRUCTURE_2lsf\| PDB=2lsf \| SCENE= }}~~		Structure and Stability of Duplex DNA Containing (5'S)-5',8-Cyclo-2'-deoxyadenosine: An Oxidative Lesion Repair by NER.,Zaliznyak T, Lukin M, de Los Santos CR Chem Res Toxicol. 2012 Aug 28. PMID:22928555<ref>PMID:22928555</ref>

	~~===Structure and Stability~~ of ~~Duplex DNA Containing (5'~~S~~) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_22928555}}~~		== References ==
			<references/>
	==~~About this Structure~~==		__TOC__
	~~[[2lsf]] is a 2 chain structure. Full experimental information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA].~~		</StructureSection>
	[[Category: Lukin, M.]]		[[Category: Lukin, M.]]
	[[Category: Santos, C de los.]]		[[Category: Santos, C de los.]]

OCA at 06:31, 3 October 2012

2012-10-03T06:31:40Z

← Older revision		Revision as of 06:31, 3 October 2012
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	[[Image:2lsf.~~jpg~~\|left\|200px]]		[[Image:2lsf.png\|left\|200px]]

	{{STRUCTURE_2lsf\| PDB=2lsf \| SCENE= }}		{{STRUCTURE_2lsf\| PDB=2lsf \| SCENE= }}

OCA at 05:10, 12 September 2012

2012-09-12T05:10:53Z

← Older revision		Revision as of 05:10, 12 September 2012
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	~~'''Unreleased structure'''~~		[[Image:2lsf.jpg\|left\|200px]]

	~~The entry~~ 2lsf ~~is ON HOLD~~ ~~until Paper Publication~~		{{STRUCTURE_2lsf\| PDB=2lsf \| SCENE= }}

	~~Authors~~: ~~Zaliznyak, T., de los Santos, C., Lukin, M.~~		===Structure and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-2'-Deoxyadenosine: An Oxidative Lesion Repair by NER===

	~~Description:~~ Structure ~~and Stability of Duplex DNA Containing (5'S) 5',8-Cyclo-~~2'-~~Deoxyadenosine~~: ~~An Oxidative Lesion Repair by NER~~		{{ABSTRACT_PUBMED_22928555}}

			==About this Structure==
			[[2lsf]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSF OCA].
			[[Category: Lukin, M.]]
			[[Category: Santos, C de los.]]
			[[Category: Zaliznyak, T.]]
			[[Category: Dna]]
			[[Category: Ner]]