2mdf - Revision history

OCA at 06:04, 15 May 2024

2024-05-15T06:04:23Z

← Older revision		Revision as of 06:04, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:31, 2 March 2023

2023-03-02T06:31:59Z

← Older revision		Revision as of 06:31, 2 March 2023
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	==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==		==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
	<StructureSection load='2mdf' size='340' side='right'caption='[[2mdf~~]], [[NMR_Ensembles_of_Models \| 25 NMR models~~]]' scene=''>		<StructureSection load='2mdf' size='340' side='right'caption='[[2mdf]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SLC9A1, APNH1, NHE1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN]] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>		[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Alves, C]]		[[Category: Alves C]]
	[[Category: Fliegel, L]]		[[Category: Fliegel L]]
	[[Category: Lee~~, B L~~]]		[[Category: Lee BL]]
	[[Category: Sykes~~, B D]]~~		[[Category: Sykes BD]]
	~~[[Category: Na+/h+ exchanger]]~~
	~~[[Category: Nhe1]]~~
	~~[[Category: Proton transport]]~~
	~~[[Category: Transmembrane~~]]

OCA at 10:07, 26 May 2021

2021-05-26T10:07:57Z

← Older revision		Revision as of 10:07, 26 May 2021
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	==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==		==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
	<StructureSection load='2mdf' size='340' side='right' caption='[[2mdf]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2mdf' size='340' side='right'caption='[[2mdf]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SLC9A1, APNH1, NHE1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SLC9A1, APNH1, NHE1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [~~http~~://pdbe.org/2mdf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [https://pdbe.org/2mdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [https://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN]] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>		[[https://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN]] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Alves, C]]		[[Category: Alves, C]]
	[[Category: Fliegel, L]]		[[Category: Fliegel, L]]

OCA at 22:52, 9 August 2018

2018-08-09T22:52:55Z

← Older revision		Revision as of 22:52, 9 August 2018
Line 1:		Line 1:

	==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==		==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
	<StructureSection load='2mdf' size='340' side='right' caption='[[2mdf]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>		<StructureSection load='2mdf' size='340' side='right' caption='[[2mdf]], [[NMR_Ensembles_of_Models \| 25 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://pdbe.org/2mdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum]</span></td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SLC9A1, APNH1, NHE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://pdbe.org/2mdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mdf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
	[[Category: Alves, C]]		[[Category: Alves, C]]
	[[Category: Fliegel, L]]		[[Category: Fliegel, L]]

OCA at 02:37, 10 September 2015

2015-09-10T02:37:24Z

← Older revision		Revision as of 02:37, 10 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://pdbe.org/2mdf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2mdf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:06, 24 December 2014

2014-12-24T16:06:09Z

← Older revision		Revision as of 16:06, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mdf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MDF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MDF FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mdf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mdf RCSB], [http://www.ebi.ac.uk/pdbsum/2mdf PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/SL9A1_HUMAN SL9A1_HUMAN]] Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.<ref>PMID:8901634</ref> <ref>PMID:11350981</ref> <ref>PMID:15035633</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Alves, C.]]		[[Category: Alves, C]]
	[[Category: Fliegel, L.]]		[[Category: Fliegel, L]]
	[[Category: Lee, B L.]]		[[Category: Lee, B L]]
	[[Category: Sykes, B D.]]		[[Category: Sykes, B D]]
	[[Category: Na+/h+ exchanger]]		[[Category: Na+/h+ exchanger]]
	[[Category: Nhe1]]		[[Category: Nhe1]]
	[[Category: Proton transport]]		[[Category: Proton transport]]
	[[Category: Transmembrane]]		[[Category: Transmembrane]]

OCA at 08:38, 2 July 2014

2014-07-02T08:38:11Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==NMR structure of a two-transmembrane segment TM VI-VII of NHE1==
-The entry 2mdf is ON HOLD  until Paper Publication
+Structural and Functional Analysis of the Transmembrane Segment Pair VI and VII of the NHE1 Isoform of the Na(+)/H(+) Exchanger.,Alves C, Lee BL, Sykes BD, Fliegel L Biochemistry. 2014 Jun 10;53(22):3658-70. doi: 10.1021/bi500392y. Epub 2014 May, 28. PMID:24840010<ref>PMID:24840010</ref>
-Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1
+== References ==

OCA at 07:04, 29 September 2013

2013-09-29T07:04:44Z

← Older revision		Revision as of 07:04, 29 September 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 2mdf is ON HOLD		The entry 2mdf is ON HOLD until Paper Publication

	Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L.		Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L.

	Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1		Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1

OCA: Protected "2mdf" [edit=sysop:move=sysop]

2013-09-20T03:10:58Z

Protected "2mdf" [edit=sysop:move=sysop]

← Older revision	Revision as of 03:10, 20 September 2013
(No difference)

OCA: New page: '''Unreleased structure''' The entry 2mdf is ON HOLD Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L. Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1

2013-09-20T03:10:57Z

New page: '''Unreleased structure''' The entry 2mdf is ON HOLD Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L. Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1

New page

'''Unreleased structure'''

The entry 2mdf is ON HOLD

Authors: Lee, B.L., Sykes, B.D., Alves, C., Fliegel, L.

Description: NMR structure of a two-transmembrane segment TM VI-VII of NHE1