2ms2 - Revision history

OCA at 09:42, 22 May 2024

2024-05-22T09:42:25Z

← Older revision		Revision as of 09:42, 22 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 2ms2" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2ms2" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Virus coat proteins 3D structures\|Virus coat proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:36, 19 April 2023

2023-04-19T09:36:16Z

← Older revision		Revision as of 09:36, 19 April 2023
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	<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacteriophage_ms2 Bacteriophage ms2~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/~~COAT_BPMS2 COAT_BPMS2~~]~~] Forms~~ the ~~phage~~ shell~~; binds~~ to the ~~phage~~ RNA.		[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacteriophage ms2~~]]		[[Category: Escherichia phage MS2]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Liljas, L]]		[[Category: Liljas L]]
	[[Category: Valegard, K]]		[[Category: Valegard K]]
	~~[[Category: Bacteriophage coat protein]]~~
	~~[[Category: Icosahedral virus]]~~
	~~[[Category: Virus~~]]

OCA at 09:02, 23 February 2022

2022-02-23T09:02:42Z

← Older revision		Revision as of 09:02, 23 February 2022
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	<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [~~http~~://pdbe.org/2ms2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.		[[https://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:27, 20 May 2020

2020-05-20T06:27:31Z

← Older revision		Revision as of 06:27, 20 May 2020
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	==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==		==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==
	<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann~~.~~ac.il/oca-docs~~/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Bacteriophage ms2]]		[[Category: Bacteriophage ms2]]
			[[Category: Large Structures]]
	[[Category: Liljas, L]]		[[Category: Liljas, L]]
	[[Category: Valegard, K]]		[[Category: Valegard, K]]

OCA at 16:52, 15 August 2018

2018-08-15T16:52:08Z

← Older revision		Revision as of 16:52, 15 August 2018
Line 1:		Line 1:

	==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==		==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==
	<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2ms2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2ms2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ms2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:40, 11 September 2015

2015-09-11T21:40:05Z

← Older revision		Revision as of 21:40, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacterio_phage_ms2 Enterobacterio phage~~ ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ms2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Enterobacterio phage~~ ms2]]		[[Category: Bacteriophage ms2]]
	[[Category: Liljas, L]]		[[Category: Liljas, L]]
	[[Category: Valegard, K]]		[[Category: Valegard, K]]

OCA at 20:00, 25 December 2014

2014-12-25T20:00:41Z

← Older revision		Revision as of 20:00, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Liljas, L.]]		[[Category: Liljas, L]]
	[[Category: Valegard, K.]]		[[Category: Valegard, K]]
	[[Category: Bacteriophage coat protein]]		[[Category: Bacteriophage coat protein]]
	[[Category: Icosahedral virus]]		[[Category: Icosahedral virus]]
	[[Category: Virus]]		[[Category: Virus]]

OCA at 19:12, 30 September 2014

2014-09-30T19:12:30Z

← Older revision		Revision as of 19:12, 30 September 2014
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	[[Image:~~2ms2~~.~~png~~\|~~left~~\|~~200px~~]]		==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==
			<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution\|resolution]] 2.80Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2ms2_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Bacteriophage MS2 is an icosahedral virus with 180 copies of a coat protein forming a shell around a single-stranded RNA molecule. The coat protein subunits form a lattice with the triangulation number T = 3. The coat protein has a fold which is different from the fold of all other viral coat proteins so far known. It consists of a five-stranded beta sheet facing the inside of the particle, and a hairpin and two helices on the outside. The crystal structure has been refined at 2.8 A resolution. The final R-factor was 0.189 for reflections with F > 2 sigma, and the root-mean-square deviation from idealized bond lengths and bond angles was 0.015 A and 2.9 degrees, respectively. The three chemically identical conformers A, B and C are largely similar. The B conformer has a unique conformation in one loop, which is involved in 5-fold interactions, while the A and C conformers, which are involved in the quasi-6-fold contacts, are similar throughout the structure. One cis-proline has been identified in the B conformer but the corresponding prolines in A and C are of the trans isomer. This residue is conserved within small RNA coliphages and it is proposed that this isomerization enables a less elongated loop (FG) around the 5-fold axis, thus creating a channel. The extensive dimer contact supports the idea of dimers as initial building blocks. An assembly pathway is proposed where five dimers converge into a pentamer and 12 pentamers are linked together with free dimers creating a complete particle.

	~~{{STRUCTURE_2ms2\| PDB=2ms2 \| SCENE= }}~~		The refined structure of bacteriophage MS2 at 2.8 A resolution.,Golmohammadi R, Valegard K, Fridborg K, Liljas L J Mol Biol. 1993 Dec 5;234(3):620-39. PMID:8254664<ref>PMID:8254664</ref>

	~~===THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_8254664}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2ms2]] is~~ a ~~3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes~~ the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:008254664<~~/~~ref~~><~~ref group="xtra">PMID:009461079</ref><references group="xtra"~~/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Liljas, L.]]		[[Category: Liljas, L.]]

OCA: Protected "2ms2" [edit=sysop:move=sysop]

2013-01-07T11:30:27Z

Protected "2ms2" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:30, 7 January 2013
(No difference)

OCA at 11:30, 7 January 2013

2013-01-07T11:30:25Z

← Older revision		Revision as of 11:30, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2ms2.png\|left\|200px]]		[[Image:2ms2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2ms2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2ms2\| PDB=2ms2 \| SCENE= }}		{{STRUCTURE_2ms2\| PDB=2ms2 \| SCENE= }}

	===THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION===		===THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_8254664}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 8254664 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_8254664}}		{{ABSTRACT_PUBMED_8254664}}

	==About this Structure==		==About this Structure==
	~~2MS2~~ is a 3 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA].		[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~8254664~~</ref><references group="xtra"/>		<ref group="xtra">PMID:008254664</ref><ref group="xtra">PMID:009461079</ref><references group="xtra"/>
	[[Category: Enterobacterio phage ms2]]		[[Category: Enterobacterio phage ms2]]
	[[Category: Liljas, L.]]		[[Category: Liljas, L.]]
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	[[Category: Bacteriophage coat protein]]		[[Category: Bacteriophage coat protein]]
	[[Category: Icosahedral virus]]		[[Category: Icosahedral virus]]
			[[Category: Virus]]
	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 05:29:39 2009''~~