2msb - Revision history

OCA at 09:02, 23 February 2022

2022-02-23T09:02:49Z

← Older revision		Revision as of 09:02, 23 February 2022
Line 3:		Line 3:
	<StructureSection load='2msb' size='340' side='right'caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2msb' size='340' side='right'caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2MSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [~~http~~://pdbe.org/2msb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2msb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2msb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [https://pdbe.org/2msb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [https://www.ebi.ac.uk/pdbsum/2msb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2msb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/MBL1_RAT MBL1_RAT]] Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).		[[https://www.uniprot.org/uniprot/MBL1_RAT MBL1_RAT]] Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:27, 20 May 2020

2020-05-20T06:27:38Z

← Older revision		Revision as of 06:27, 20 May 2020
Line 1:		Line 1:

	==STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE==		==STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE==
	<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2msb' size='340' side='right'caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann.ac~~.~~il/oca-docs~~/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://pdbe.org/2msb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2msb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://pdbe.org/2msb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2msb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Black rat]]		[[Category: Black rat]]
			[[Category: Large Structures]]
	[[Category: Drickamer, K]]		[[Category: Drickamer, K]]
	[[Category: Hendrickson, W A]]		[[Category: Hendrickson, W A]]
	[[Category: Weis, W I]]		[[Category: Weis, W I]]
	[[Category: Lectin]]		[[Category: Lectin]]

OCA at 17:31, 15 August 2018

2018-08-15T17:31:14Z

← Older revision		Revision as of 17:31, 15 August 2018
Line 1:		Line 1:

	==STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE==		==STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE==
	<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://pdbe.org/2msb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://pdbe.org/2msb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2msb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2msb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2msb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 2msb" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2msb" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Mannose-binding protein\|Mannose-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:16, 8 February 2016

2016-02-08T10:16:24Z

← Older revision		Revision as of 10:16, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2msb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:34, 10 September 2015

2015-09-10T10:34:42Z

← Older revision		Revision as of 10:34, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Rattus_rattus Rattus rattus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Black_rat Black rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://pdbe.org/2msb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/MBL1_RAT MBL1_RAT]] Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2msb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Rattus rattus~~]]		[[Category: Black rat]]
	[[Category: Drickamer, K]]		[[Category: Drickamer, K]]
	[[Category: Hendrickson, W A]]		[[Category: Hendrickson, W A]]
	[[Category: Weis, W I]]		[[Category: Weis, W I]]
	[[Category: Lectin]]		[[Category: Lectin]]

OCA at 14:25, 19 January 2015

2015-01-19T14:25:24Z

← Older revision		Revision as of 14:25, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Rattus rattus]]		[[Category: Rattus rattus]]
	[[Category: Drickamer, K.]]		[[Category: Drickamer, K]]
	[[Category: Hendrickson, W A.]]		[[Category: Hendrickson, W A]]
	[[Category: Weis, W I.]]		[[Category: Weis, W I]]
	[[Category: Lectin]]		[[Category: Lectin]]

OCA at 18:28, 30 September 2014

2014-09-30T18:28:56Z

← Older revision		Revision as of 18:28, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2msb~~.~~png~~\|~~left~~\|~~200px~~]]		==STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE==
			<StructureSection load='2msb' size='340' side='right' caption='[[2msb]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MSB FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2msb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2msb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2msb RCSB], [http://www.ebi.ac.uk/pdbsum/2msb PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/2msb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			C-type (Ca(2+)-dependent) animal lectins such as mannose-binding proteins mediate many cell-surface carbohydrate-recognition events. The crystal structure at 1.7 A resolution of the carbohydrate-recognition domain of rat mannose-binding protein complexed with an oligomannose asparaginyl-oligosaccharide reveals that Ca2+ forms coordination bonds with the carbohydrate ligand. Carbohydrate specificity is determined by a network of coordination and hydrogen bonds that stabilizes the ternary complex of protein, Ca2+ and sugar. Two branches of the oligosaccharide crosslink neighbouring carbohydrate-recognition domains in the crystal, enabling multivalent binding to a single oligosaccharide chain to be visualized directly.

	~~{{STRUCTURE_2msb\| PDB=2msb \| SCENE= }}~~		Structure of a C-type mannose-binding protein complexed with an oligosaccharide.,Weis WI, Drickamer K, Hendrickson WA Nature. 1992 Nov 12;360(6400):127-34. PMID:1436090<ref>PMID:1436090</ref>

	~~===STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_1436090}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2msb]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_rattus Rattus rattus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:001436090<~~/~~ref~~><~~ref group="xtra">PMID:012856000</ref><ref group="xtra">PMID:016245931</ref><references group="xtra"~~/>
	[[Category: Rattus rattus]]		[[Category: Rattus rattus]]
	[[Category: Drickamer, K.]]		[[Category: Drickamer, K.]]

OCA: Protected "2msb" [edit=sysop:move=sysop]

2013-01-07T10:44:16Z

Protected "2msb" [edit=sysop:move=sysop]

← Older revision	Revision as of 10:44, 7 January 2013
(No difference)

OCA at 10:44, 7 January 2013

2013-01-07T10:44:13Z

← Older revision		Revision as of 10:44, 7 January 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2msb.png\|left\|200px]]		[[Image:2msb.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2msb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2msb\| PDB=2msb \| SCENE= }}		{{STRUCTURE_2msb\| PDB=2msb \| SCENE= }}

	===STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE===		===STRUCTURE OF A C-TYPE MANNOSE-BINDING PROTEIN COMPLEXED WITH AN OLIGOSACCHARIDE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_1436090}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 1436090 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_1436090}}		{{ABSTRACT_PUBMED_1436090}}

	==About this Structure==		==About this Structure==
	~~2MSB~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA].		[[2msb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~1436090~~</ref><references group="xtra"/>		<ref group="xtra">PMID:001436090</ref><ref group="xtra">PMID:012856000</ref><ref group="xtra">PMID:016245931</ref><references group="xtra"/>
	[[Category: Rattus rattus]]		[[Category: Rattus rattus]]
	[[Category: Drickamer, K.]]		[[Category: Drickamer, K.]]
Line 29:		Line 17:
	[[Category: Weis, W I.]]		[[Category: Weis, W I.]]
	[[Category: Lectin]]		[[Category: Lectin]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:55:48 2009''~~

OCA at 16:55, 21 September 2009

2009-09-21T16:55:49Z

← Older revision		Revision as of 16:55, 21 September 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
	2MSB is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA].		2MSB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MSB OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:1436090</ref><references group="xtra"/>		<ref group="xtra">PMID:1436090</ref><references group="xtra"/>
			[[Category: Rattus rattus]]
	[[Category: Drickamer, K.]]		[[Category: Drickamer, K.]]
	[[Category: Hendrickson, W A.]]		[[Category: Hendrickson, W A.]]
Line 29:		Line 30:
	[[Category: Lectin]]		[[Category: Lectin]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon ~~Feb 16~~ 21:16:00 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:55:48 2009''