2mtf - Revision history

OCA at 06:10, 15 May 2024

2024-05-15T06:10:12Z

← Older revision		Revision as of 06:10, 15 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:06, 8 March 2023

2023-03-08T08:06:22Z

← Older revision		Revision as of 08:06, 8 March 2023
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	==Solution structure of the La motif of human LARP6==		==Solution structure of the La motif of human LARP6==
	<StructureSection load='2mtf' size='340' side='right'caption='[[2mtf~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2mtf' size='340' side='right'caption='[[2mtf]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
	</td></tr>~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LARP6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>~~		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN]] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>		[https://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Atkinson~~, A R~~]]		[[Category: Atkinson AR]]
	[[Category: Conte~~, M R~~]]		[[Category: Conte MR]]
	[[Category: Kelly, G]]		[[Category: Kelly G]]
	[[Category: Martino, L]]		[[Category: Martino L]]
	[[Category: Salisbury~~, N JH]]~~		[[Category: Salisbury NJH]]
	~~[[Category: Acheron]]~~
	~~[[Category: La motif]]~~
	~~[[Category: La-related protein]]~~
	~~[[Category: Larp]]~~
	~~[[Category: Larp6]]~~
	~~[[Category: Rna binding protein~~]]

OCA at 15:20, 2 June 2021

2021-06-02T15:20:46Z

← Older revision		Revision as of 15:20, 2 June 2021
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	==Solution structure of the La motif of human LARP6==		==Solution structure of the La motif of human LARP6==
	<StructureSection load='2mtf' size='340' side='right' caption='[[2mtf]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mtf' size='340' side='right'caption='[[2mtf]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2MTF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LARP6 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LARP6 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [~~http~~://pdbe.org/2mtf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [https://pdbe.org/2mtf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [https://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN]] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>		[[https://www.uniprot.org/uniprot/LARP6_HUMAN LARP6_HUMAN]] Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.<ref>PMID:20603131</ref> <ref>PMID:21746880</ref> <ref>PMID:22190748</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Atkinson, A R]]		[[Category: Atkinson, A R]]
	[[Category: Conte, M R]]		[[Category: Conte, M R]]

OCA at 17:30, 15 August 2018

2018-08-15T17:30:24Z

← Older revision		Revision as of 17:30, 15 August 2018
Line 1:		Line 1:

	==Solution structure of the La motif of human LARP6==		==Solution structure of the La motif of human LARP6==
	<StructureSection load='2mtf' size='340' side='right' caption='[[2mtf]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2mtf' size='340' side='right' caption='[[2mtf]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MTF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [http://pdbe.org/2mtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [http://www.ebi.ac.uk/pdbsum/2mtf PDBsum]</span></td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LARP6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [http://pdbe.org/2mtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [http://www.ebi.ac.uk/pdbsum/2mtf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mtf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Human]]
	[[Category: Atkinson, A R]]		[[Category: Atkinson, A R]]
	[[Category: Conte, M R]]		[[Category: Conte, M R]]

OCA at 14:31, 10 September 2015

2015-09-10T14:31:33Z

← Older revision		Revision as of 14:31, 10 September 2015
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MTF FirstGlance]. <br>		<table><tr><td colspan='2'>[[2mtf]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MTF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MTF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [http://www.ebi.ac.uk/pdbsum/2mtf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mtf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mtf OCA], [http://pdbe.org/2mtf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mtf RCSB], [http://www.ebi.ac.uk/pdbsum/2mtf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2mtf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:51, 24 December 2014

2014-12-24T10:51:47Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Solution structure of the La motif of human LARP6==
-The entry 2mtf is ON HOLD  until Paper Publication
+Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.,Martino L, Pennell S, Kelly G, Busi B, Brown P, Atkinson RA, Salisbury NJ, Ooi ZH, See KW, Smerdon SJ, Alfano C, Bui TT, Conte MR Nucleic Acids Res. 2014 Dec 8. pii: gku1287. PMID:25488812<ref>PMID:25488812</ref>
-Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description: Solution structure of the La motif of human LARP6
+== References ==

OCA at 09:00, 22 October 2014

2014-10-22T09:00:44Z

← Older revision		Revision as of 09:00, 22 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 2mtf is ON HOLD		The entry 2mtf is ON HOLD until Paper Publication

	Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R.		Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R.

	Description: Solution structure of the La motif of human LARP6		Description: Solution structure of the La motif of human LARP6

OCA: Protected "2mtf" [edit=sysop:move=sysop]

2014-08-27T06:06:22Z

Protected "2mtf" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:06, 27 August 2014
(No difference)

OCA: New page: '''Unreleased structure''' The entry 2mtf is ON HOLD Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R. Description: Solution structure of the La motif of h...

2014-08-27T06:06:20Z

New page: '''Unreleased structure''' The entry 2mtf is ON HOLD Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R. Description: Solution structure of the La motif of h...

New page

'''Unreleased structure'''

The entry 2mtf is ON HOLD

Authors: Martino, L., Salisbury, N.JH., Atkinson, A.R., Kelly, G., Conte, M.R.

Description: Solution structure of the La motif of human LARP6