2o4e - Revision history

OCA at 10:02, 14 June 2023

2023-06-14T10:02:10Z

← Older revision		Revision as of 10:02, 14 June 2023
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	==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==		==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==
	<StructureSection load='2o4e' size='340' side='right'caption='[[2o4e~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2o4e' size='340' side='right'caption='[[2o4e]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus~~ perfringens~~" veillon and zuber 1898~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [https://pdbe.org/2o4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [https://www.ebi.ac.uk/pdbsum/2o4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4e ProSAT]</span></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [https://pdbe.org/2o4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [https://www.ebi.ac.uk/pdbsum/2o4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/OGA_CLOP1 OGA_CLOP1]] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.		[https://www.uniprot.org/uniprot/OGA_CLOP1 OGA_CLOP1] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ perfringens ~~veillon and zuber 1898]]~~		[[Category: Clostridium perfringens]]
	~~[[Category: Beta-N-acetylhexosaminidase~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Adams~~, J J~~]]		[[Category: Adams JJ]]
	[[Category: Boraston~~, A B~~]]		[[Category: Boraston AB]]
	[[Category: Chitayat, S]]		[[Category: Chitayat S]]
	[[Category: Gregg, K]]		[[Category: Gregg K]]
	[[Category: Smith~~, S P]]~~		[[Category: Smith SP]]
	~~[[Category: Beta-barrel]]~~
	~~[[Category: Protein binding~~]]

OCA at 18:13, 20 October 2021

2021-10-20T18:13:24Z

← Older revision		Revision as of 18:13, 20 October 2021
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	<StructureSection load='2o4e' size='340' side='right'caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2o4e' size='340' side='right'caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2O4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [~~http~~://pdbe.org/2o4e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2o4e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4e ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [https://pdbe.org/2o4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [https://www.ebi.ac.uk/pdbsum/2o4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/OGA_CLOP1 OGA_CLOP1]] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.		[[https://www.uniprot.org/uniprot/OGA_CLOP1 OGA_CLOP1]] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
	*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]		*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
			*[[O-GlcNAcase\|O-GlcNAcase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:34, 5 February 2020

2020-02-05T08:34:52Z

← Older revision		Revision as of 08:34, 5 February 2020
Line 1:		Line 1:

	==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==		==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==
	<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2o4e' size='340' side='right'caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
			*[[Beta-Hexosaminidase 3D structures\|Beta-Hexosaminidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 29:
	[[Category: Bacillus perfringens veillon and zuber 1898]]		[[Category: Bacillus perfringens veillon and zuber 1898]]
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
			[[Category: Large Structures]]
	[[Category: Adams, J J]]		[[Category: Adams, J J]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 06:55, 22 August 2018

2018-08-22T06:55:10Z

← Older revision		Revision as of 06:55, 22 August 2018
Line 1:		Line 1:

	==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==		==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==
	<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://pdbe.org/2o4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://pdbe.org/2o4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2o4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:20, 11 September 2015

2015-09-11T08:20:23Z

← Older revision		Revision as of 08:20, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_perfringens Clostridium~~ perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 ~~Clostridium~~ perfringens])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 "Bacillus perfringens" Veillon and Zuber 1898])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://pdbe.org/2o4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2o4e" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Bacillus perfringens veillon and zuber 1898]]
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	~~[[Category: Clostridium perfringens]]~~
	[[Category: Adams, J J]]		[[Category: Adams, J J]]
	[[Category: Boraston, A B]]		[[Category: Boraston, A B]]

OCA at 13:47, 25 December 2014

2014-12-25T13:47:22Z

← Older revision		Revision as of 13:47, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 Clostridium perfringens])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 Clostridium perfringens])</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/OGA_CLOP1 OGA_CLOP1]] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Clostridium perfringens]]		[[Category: Clostridium perfringens]]
	[[Category: Adams, J J.]]		[[Category: Adams, J J]]
	[[Category: Boraston, A B.]]		[[Category: Boraston, A B]]
	[[Category: Chitayat, S.]]		[[Category: Chitayat, S]]
	[[Category: Gregg, K.]]		[[Category: Gregg, K]]
	[[Category: Smith, S P.]]		[[Category: Smith, S P]]
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

OCA at 05:03, 29 September 2014

2014-09-29T05:03:23Z

← Older revision		Revision as of 05:03, 29 September 2014
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	[[~~Image~~:2o4e.~~png\|left\|200px~~]]		==The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens==
			<StructureSection load='2o4e' size='340' side='right' caption='[[2o4e]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2O4E FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nagJ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1502 Clostridium perfringens])</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o4e RCSB], [http://www.ebi.ac.uk/pdbsum/2o4e PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The genomes of myonecrotic strains of Clostridium perfringens encode a large number of secreted glycoside hydrolases. The activities of these enzymes are consistent with degradation of the mucosal layer of the human gastrointestinal tract, glycosaminoglycans and other cellular glycans found throughout the body. In many cases this is thought to aid in the propagation of the major toxins produced by C. perfringens. One such example is the family 84 glycoside hydrolases, which contains five C. perfringens members (CpGH84A-E), each displaying a unique modular architecture. The smallest and most extensively studied member, CpGH84C, comprises an N-terminal catalytic domain with beta-N-acetylglucosaminidase activity, a family 32 carbohydrate-binding module, a family 82 X-module (X82) of unknown function, and a fibronectin type-III-like module. Here we present the structure of the X82 module from CpGH84C, determined by both NMR spectroscopy and X-ray crystallography. CpGH84C X82 adopts a jell-roll fold comprising two beta-sheets formed by nine beta-strands. CpGH84C X82 displays distant amino acid sequence identity yet close structural similarity to the cohesin modules of cellulolytic anaerobic bacteria. Cohesin modules are responsible for the assembly of numerous hydrolytic enzymes in a cellulose-degrading multi-enzyme complex, termed the cellulosome, through a high-affinity interaction with the calcium-binding dockerin module. A planar surface is located on the face of the CpGH84 X82 structure that corresponds to the dockerin-binding region of cellulolytic cohesin modules and has the approximate dimensions to accommodate a dockerin module. The presence of cohesin-like X82 modules in glycoside hydrolases of C. perfringens is an indication that the formation of novel X82-dockerin mediated multi-enzyme complexes, with potential roles in pathogenesis, is possible.

	~~{{STRUCTURE_2o4e\| PDB=2o4e \| SCENE= }}~~		Three-dimensional structure of a putative non-cellulosomal cohesin module from a Clostridium perfringens family 84 glycoside hydrolase.,Chitayat S, Gregg K, Adams JJ, Ficko-Blean E, Bayer EA, Boraston AB, Smith SP J Mol Biol. 2008 Jan 4;375(1):20-8. Epub 2007 Oct 17. PMID:17999932<ref>PMID:17999932</ref>

	~~===The solution structure of a protein-protein interaction module from~~ a ~~family 84 glycoside hydrolase~~ of ~~Clostridium perfringens===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17999932}}~~

	~~==About this Structure==~~
	~~[[2o4e]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Clostridium_perfringens Clostridium perfringens]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA].~~

	==See Also==		==See Also==
	*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]		*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:017999932<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Clostridium perfringens]]		[[Category: Clostridium perfringens]]

OCA at 17:25, 20 October 2012

2012-10-20T17:25:52Z

← Older revision		Revision as of 17:25, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2o4e]] is a 1 chain structure ~~of [[Beta-Hexosaminidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA].		[[2o4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA].

	==See Also==		==See Also==

OCA: Protected "2o4e" [edit=sysop:move=sysop]

2012-07-27T00:51:59Z

Protected "2o4e" [edit=sysop:move=sysop]

← Older revision	Revision as of 00:51, 27 July 2012
(No difference)

OCA at 00:51, 27 July 2012

2012-07-27T00:51:57Z

← Older revision		Revision as of 00:51, 27 July 2012
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	~~{{Seed}}~~
	[[Image:2o4e.png\|left\|200px]]		[[Image:2o4e.png\|left\|200px]]

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	{{STRUCTURE_2o4e\| PDB=2o4e \| SCENE= }}		{{STRUCTURE_2o4e\| PDB=2o4e \| SCENE= }}

	===The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens===		===The solution structure of a protein-protein interaction module from a family 84 glycoside hydrolase of Clostridium perfringens===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17999932}}, adds the Publication Abstract to the page~~
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	==About this Structure==		==About this Structure==
	~~2O4E~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA].		[[2o4e]] is a 1 chain structure of [[Beta-Hexosaminidase]] with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O4E OCA].

			==See Also==
			*[[Beta-Hexosaminidase\|Beta-Hexosaminidase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17999932~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017999932</ref><references group="xtra"/>
	[[Category: Beta-N-acetylhexosaminidase]]		[[Category: Beta-N-acetylhexosaminidase]]
	[[Category: Clostridium perfringens]]		[[Category: Clostridium perfringens]]
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	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Protein binding]]		[[Category: Protein binding]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:32:05 2010''~~