2oki - Revision history

OCA at 08:57, 25 October 2023

2023-10-25T08:57:55Z

← Older revision		Revision as of 08:57, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='2oki' size='340' side='right'caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2oki' size='340' side='right'caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Plafa Plafa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OKI FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">fabz ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax~~.~~cgi?mode=Info~~&~~srchmode=5&id=5833 PLAFA])</td></tr>~~
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [https://pdbe.org/2oki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [https://www.ebi.ac.uk/pdbsum/2oki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oki ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [https://pdbe.org/2oki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [https://www.ebi.ac.uk/pdbsum/2oki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oki ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q965D7_PLAFA Q965D7_PLAFA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Plafa~~]]		[[Category: Plasmodium falciparum]]
	[[Category: Padala, P]]		[[Category: Padala P]]
	[[Category: Sharma~~, S K~~]]		[[Category: Sharma SK]]
	[[Category: Suguna, K]]		[[Category: Suguna K]]
	[[Category: Surolia, A]]		[[Category: Surolia A]]
	[[Category: Surolia, N]]		[[Category: Surolia N]]
	[[Category: Swarnamukhi~~, P L]]~~		[[Category: Swarnamukhi PL]]
	~~[[Category: Fabz]]~~
	~~[[Category: Hotdog fold]]~~
	~~[[Category: Lyase]]~~
	~~[[Category: Non-isomorphism]]~~
	~~[[Category: Plasmodium~~]]

OCA at 12:58, 9 June 2021

2021-06-09T12:58:47Z

← Older revision		Revision as of 12:58, 9 June 2021
Line 1:		Line 1:

	==Crystal structure of dimeric form of PfFabZ in crystal form2==		==Crystal structure of dimeric form of PfFabZ in crystal form2==
	<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2oki' size='340' side='right'caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2OKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OKI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [~~http~~://pdbe.org/2oki PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2oki PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2oki ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [https://pdbe.org/2oki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [https://www.ebi.ac.uk/pdbsum/2oki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oki ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:

	==See Also==		==See Also==
	*[[Beta-hydroxyacyl-acyl carrier protein dehydratase\|Beta-hydroxyacyl-acyl carrier protein dehydratase]]		*[[Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures\|Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Plafa]]		[[Category: Plafa]]
	[[Category: Padala, P]]		[[Category: Padala, P]]

OCA at 07:17, 22 August 2018

2018-08-22T07:17:54Z

← Older revision		Revision as of 07:17, 22 August 2018
Line 1:		Line 1:

	==Crystal structure of dimeric form of PfFabZ in crystal form2==		==Crystal structure of dimeric form of PfFabZ in crystal form2==
	<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://pdbe.org/2oki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://pdbe.org/2oki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2oki ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/2oki_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/2oki_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oki ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:07, 11 September 2015

2015-09-11T10:07:59Z

← Older revision		Revision as of 10:07, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Plasmodium_falciparum Plasmodium falciparum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OKI FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 ~~Plasmodium falciparum~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-~~hydroxydecanoyl~~-[acyl-carrier-protein]_dehydratase 3-~~hydroxydecanoyl~~-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.60 4.2.1.60] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyacyl-[acyl-carrier-protein]_dehydratase 3-hydroxyacyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.59 4.2.1.59] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://pdbe.org/2oki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2oki" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Plasmodium falciparum~~]]		[[Category: Plafa]]
	[[Category: Padala, P]]		[[Category: Padala, P]]
	[[Category: Sharma, S K]]		[[Category: Sharma, S K]]

OCA at 18:18, 19 January 2015

2015-01-19T18:18:14Z

← Older revision		Revision as of 18:18, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OKI FirstGlance]. <br>		<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OKI FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxydecanoyl-[acyl-carrier-protein]_dehydratase 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.60 4.2.1.60] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxydecanoyl-[acyl-carrier-protein]_dehydratase 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.60 4.2.1.60] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Padala, P.]]		[[Category: Padala, P]]
	[[Category: Sharma, S K.]]		[[Category: Sharma, S K]]
	[[Category: Suguna, K.]]		[[Category: Suguna, K]]
	[[Category: Surolia, A.]]		[[Category: Surolia, A]]
	[[Category: Surolia, N.]]		[[Category: Surolia, N]]
	[[Category: Swarnamukhi, P L.]]		[[Category: Swarnamukhi, P L]]
	[[Category: Fabz]]		[[Category: Fabz]]
	[[Category: Hotdog fold]]		[[Category: Hotdog fold]]

OCA at 20:11, 30 September 2014

2014-09-30T20:11:41Z

← Older revision		Revision as of 20:11, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2oki~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of dimeric form of PfFabZ in crystal form2==
			<StructureSection load='2oki' size='340' side='right' caption='[[2oki]], [[Resolution\|resolution]] 2.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OKI FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2okh\|2okh]], [[1zhg\|1zhg]], [[1u1z\|1u1z]], [[1z6b\|1z6b]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">fabz ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxydecanoyl-[acyl-carrier-protein]_dehydratase 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.60 4.2.1.60] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2oki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oki OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2oki RCSB], [http://www.ebi.ac.uk/pdbsum/2oki PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ok/2oki_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The crystals obtained from various batches of crystallization trials of FabZ from Plasmodium falciparum exhibited non-isomorphism. The c axis of the I222 cell showed a large variation of about 16 A, from c = 81 A to c = 97 A. Complete data sets were collected for three crystal forms with varying lengths of the c axis (form 1, c = 97 A; form 2, c = 92 A; form 3, c = 81 A). The crystal structure of form 1 has been reported previously. Here, the crystal structures of the other two crystal forms are reported and a detailed structural comparison is made of the three crystal forms in order to explore the possible reasons for the existence of non-isomorphism. The conformations of three loops vary between the three crystal forms. The disposition of the loops affects the crystal packing and hence the unit-cell parameter. The crystallization condition and crystallization method employed, which change the evaporation rate, determine the crystal form of the enzyme. The present analysis shows that pH-induced intrinsic conformational changes in the protein play a key role in the observed differences.

	~~{{STRUCTURE_2oki\| PDB=2oki \| SCENE= }}~~		Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum.,Swarnamukhi PL, Sharma SK, Padala P, Surolia N, Surolia A, Suguna K Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):458-64. Epub 2007, Mar 16. PMID:17372349<ref>PMID:17372349</ref>

	~~===Crystal structure~~ of ~~dimeric form~~ of ~~PfFabZ in crystal form2===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	~~{{ABSTRACT_PUBMED_17372349}}~~		==See Also==
			*[[Beta-hydroxyacyl-acyl carrier protein dehydratase\|Beta-hydroxyacyl-acyl carrier protein dehydratase]]
	==~~About this Structure~~==		== References ==
	[[~~2oki~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA].		<references/>
			__TOC__
	==~~Reference~~==		</StructureSection>
	<~~ref group="xtra">PMID:017372349<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Padala, P.]]		[[Category: Padala, P.]]

OCA: Protected "2oki" [edit=sysop:move=sysop]

2013-01-07T15:14:30Z

Protected "2oki" [edit=sysop:move=sysop]

← Older revision	Revision as of 15:14, 7 January 2013
(No difference)

OCA at 15:14, 7 January 2013

2013-01-07T15:14:28Z

← Older revision		Revision as of 15:14, 7 January 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2oki.png\|left\|200px]]		[[Image:2oki.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2oki", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2oki\| PDB=2oki \| SCENE= }}		{{STRUCTURE_2oki\| PDB=2oki \| SCENE= }}

	===Crystal structure of dimeric form of PfFabZ in crystal form2===		===Crystal structure of dimeric form of PfFabZ in crystal form2===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17372349}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17372349 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_17372349}}		{{ABSTRACT_PUBMED_17372349}}

	==About this Structure==		==About this Structure==
	~~2OKI~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA].		[[2oki]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17372349~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017372349</ref><references group="xtra"/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Padala, P.]]		[[Category: Padala, P.]]
Line 33:		Line 21:
	[[Category: Fabz]]		[[Category: Fabz]]
	[[Category: Hotdog fold]]		[[Category: Hotdog fold]]
			[[Category: Lyase]]
	[[Category: Non-isomorphism]]		[[Category: Non-isomorphism]]
	[[Category: Plasmodium]]		[[Category: Plasmodium]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:25:11 2009''~~

OCA at 17:25, 17 February 2009

2009-02-17T17:25:15Z

← Older revision		Revision as of 17:25, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
	2OKI is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA].		2OKI is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OKI OCA].

	==Reference==		==Reference==
	Packing and loop-structure variations in non-isomorphous crystals of FabZ from Plasmodium falciparum., Swarnamukhi PL, Sharma SK, Padala P, Surolia N, Surolia A, Suguna K, Acta Crystallogr D Biol Crystallogr. 2007 Apr;63(Pt 4):458-64. Epub 2007, Mar 16. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/17372349 17372349]~~		<ref group="xtra">PMID:17372349</ref><references group="xtra"/>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	~~[[Category: Single protein]]~~
	[[Category: Padala, P.]]		[[Category: Padala, P.]]
	[[Category: Sharma, S K.]]		[[Category: Sharma, S K.]]
Line 37:		Line 36:
	[[Category: Plasmodium]]		[[Category: Plasmodium]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 29 03~~:26:~~47 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:25:11 2009''

OCA at 00:26, 29 July 2008

2008-07-29T00:26:51Z

← Older revision		Revision as of 00:26, 29 July 2008
Line 1:		Line 1:
	[[Image:2oki.~~gif~~\|left\|200px]]		{{Seed}}
			[[Image:2oki.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_2oki\| PDB=2oki \| SCENE= }}		{{STRUCTURE_2oki\| PDB=2oki \| SCENE= }}

	~~'''~~Crystal structure of dimeric form of PfFabZ in crystal form2~~'''~~		===Crystal structure of dimeric form of PfFabZ in crystal form2===


	~~==Overview==~~		<!--
	The ~~crystals obtained from various batches of crystallization trials of FabZ from Plasmodium falciparum exhibited non-isomorphism. The c axis of~~ the ~~I222 cell showed a large variation of about 16 A, from c = 81 A~~ to ~~c = 97 A. Complete data sets were collected for three crystal forms with varying lengths of~~ the ~~c axis~~ (~~form 1, c = 97 A; form 2, c = 92 A; form 3, c = 81 A)~~. ~~The crystal structure of form 1 has been reported previously~~. ~~Here~~, ~~the crystal structures of the other two crystal forms are reported and a detailed structural comparison~~ is ~~made of~~ the ~~three crystal forms in order to explore the possible reasons for the existence of non-isomorphism~~. ~~The conformations of three loops vary between the three crystal forms. The disposition of the loops affects the crystal packing and hence the unit~~-~~cell parameter. The crystallization condition and crystallization method employed, which change the evaporation rate, determine the crystal form of the enzyme. The present analysis shows that pH~~-~~induced intrinsic conformational changes in the protein play a key role in the observed differences.~~		The line below this paragraph, {{ABSTRACT_PUBMED_17372349}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 17372349 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_17372349}}

	==About this Structure==		==About this Structure==
Line 32:		Line 36:
	[[Category: Non-isomorphism]]		[[Category: Non-isomorphism]]
	[[Category: Plasmodium]]		[[Category: Plasmodium]]
	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May 4 11~~:05:54 2008''
			''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 03:26:47 2008''