2ons - Revision history

OCA at 08:26, 13 August 2026

2026-08-13T08:26:24Z

← Older revision		Revision as of 08:26, 13 August 2026
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ons_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ons_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 00:20, 28 December 2023

2023-12-28T00:20:57Z

← Older revision		Revision as of 00:20, 28 December 2023
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	<StructureSection load='2ons' size='340' side='right'caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2ons' size='340' side='right'caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arcfu Arcfu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ONS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ONS FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~, ~~<scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[2onr\|2onr]]~~</~~div~~><~~/td~~></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></~~td><td class="sblockDat"~~>~~AF_0094 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [https://pdbe.org/2ons PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [https://www.ebi.ac.uk/pdbsum/2ons PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ons ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [https://pdbe.org/2ons PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [https://www.ebi.ac.uk/pdbsum/2ons PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ons ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/WTPA_ARCFU WTPA_ARCFU]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.		[https://www.uniprot.org/uniprot/WTPA_ARCFU WTPA_ARCFU] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Arcfu~~]]		[[Category: Archaeoglobus fulgidus DSM 4304]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Frei~~, D C~~]]		[[Category: Frei DC]]
	[[Category: Hollenstein, K]]		[[Category: Hollenstein K]]
	[[Category: Locher~~, K P]]~~		[[Category: Locher KP]]
	~~[[Category: Ligand binding protein]]~~
	~~[[Category: Soluble protein 2~~]]

OCA at 13:01, 9 June 2021

2021-06-09T13:01:08Z

← Older revision		Revision as of 13:01, 9 June 2021
Line 1:		Line 1:

	==Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate==		==Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate==
	<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2ons' size='340' side='right'caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ONS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ONS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2onr\|2onr]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [~~http~~://pdbe.org/2ons PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ons PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ons ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [https://pdbe.org/2ons PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [https://www.ebi.ac.uk/pdbsum/2ons PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ons ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/WTPA_ARCFU WTPA_ARCFU]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.		[[https://www.uniprot.org/uniprot/WTPA_ARCFU WTPA_ARCFU]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Arcfu]]		[[Category: Arcfu]]
			[[Category: Large Structures]]
	[[Category: Frei, D C]]		[[Category: Frei, D C]]
	[[Category: Hollenstein, K]]		[[Category: Hollenstein, K]]

OCA at 06:52, 22 August 2018

2018-08-22T06:52:13Z

← Older revision		Revision as of 06:52, 22 August 2018
Line 1:		Line 1:

	==Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate==		==Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate==
	<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://pdbe.org/2ons PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://pdbe.org/2ons PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ons ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ons_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ons_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:12, 8 February 2016

2016-02-08T16:12:08Z

← Older revision		Revision as of 16:12, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ons ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:16, 10 September 2015

2015-09-10T13:16:34Z

← Older revision		Revision as of 13:16, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ONS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfu Arcfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ONS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ~~Archaeoglobus fulgidus DSM 4304~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 ARCFU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://pdbe.org/2ons PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~Y094_ARCFU Y094_ARCFU~~]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.		[[http://www.uniprot.org/uniprot/WTPA_ARCFU WTPA_ARCFU]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ons" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Archaeoglobus fulgidus dsm 4304~~]]		[[Category: Arcfu]]
	[[Category: Frei, D C]]		[[Category: Frei, D C]]
	[[Category: Hollenstein, K]]		[[Category: Hollenstein, K]]

OCA at 00:33, 25 December 2014

2014-12-25T00:33:41Z

← Older revision		Revision as of 00:33, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ONS FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ONS FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 Archaeoglobus fulgidus DSM 4304])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 Archaeoglobus fulgidus DSM 4304])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/Y094_ARCFU Y094_ARCFU]] Part of the ABC transporter complex WtpABC involved in molybdate/tungstate import. Binds tungstate and molybdate.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Archaeoglobus fulgidus dsm 4304]]		[[Category: Archaeoglobus fulgidus dsm 4304]]
	[[Category: Frei, D C.]]		[[Category: Frei, D C]]
	[[Category: Hollenstein, K.]]		[[Category: Hollenstein, K]]
	[[Category: Locher, K P.]]		[[Category: Locher, K P]]
	[[Category: Ligand binding protein]]		[[Category: Ligand binding protein]]
	[[Category: Soluble protein 2]]		[[Category: Soluble protein 2]]

OCA at 06:23, 29 September 2014

2014-09-29T06:23:53Z

← Older revision		Revision as of 06:23, 29 September 2014
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	[[Image:~~2ons~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate==
			<StructureSection load='2ons' size='340' side='right' caption='[[2ons]], [[Resolution\|resolution]] 1.55Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ONS FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WO4:TUNGSTATE(VI)ION'>WO4</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2onr\|2onr]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AF_0094 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224325 Archaeoglobus fulgidus DSM 4304])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ons FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ons OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ons RCSB], [http://www.ebi.ac.uk/pdbsum/2ons PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/on/2ons_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			ATP-binding cassette (ABC) transporter proteins carry diverse substrates across cell membranes. Whereas clinically relevant ABC exporters are implicated in various diseases or cause multidrug resistance of cancer cells, bacterial ABC importers are essential for the uptake of nutrients, including rare elements such as molybdenum. A detailed understanding of their mechanisms requires direct visualization at high resolution and in distinct conformations. Our recent structure of the multidrug ABC exporter Sav1866 has revealed an outward-facing conformation of the transmembrane domains coupled to a closed conformation of the nucleotide-binding domains, reflecting the ATP-bound state. Here we present the 3.1 A crystal structure of a putative molybdate transporter (ModB2C2) from Archaeoglobus fulgidus in complex with its binding protein (ModA). Twelve transmembrane helices of the ModB subunits provide an inward-facing conformation, with a closed gate near the external membrane boundary. The ATP-hydrolysing ModC subunits reveal a nucleotide-free, open conformation, whereas the attached binding protein aligns the substrate-binding cleft with the entrance to the presumed translocation pathway. Structural comparison of ModB2C2A with Sav1866 suggests a common alternating access and release mechanism, with binding of ATP promoting an outward-facing conformation and dissociation of the hydrolysis products promoting an inward-facing conformation.

	~~{{STRUCTURE_2ons\| PDB=2ons \| SCENE= }}~~		Structure of an ABC transporter in complex with its binding protein.,Hollenstein K, Frei DC, Locher KP Nature. 2007 Mar 8;446(7132):213-6. Epub 2007 Feb 25. PMID:17322901<ref>PMID:17322901</ref>

	~~===Crystal structure~~ of A. ~~fulgidus periplasmic binding protein ModA with bound tungstate===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17322901}}~~

	~~==About this Structure==~~
	~~[[2ons]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA].~~

	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter\|ABC transporter]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:017322901<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Archaeoglobus fulgidus dsm 4304]]		[[Category: Archaeoglobus fulgidus dsm 4304]]
	[[Category: Frei, D C.]]		[[Category: Frei, D C.]]

OCA at 10:43, 20 October 2012

2012-10-20T10:43:11Z

← Older revision		Revision as of 10:43, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2ons]] is a 1 chain structure ~~of [[ABC transporter]]~~ with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA].		[[2ons]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_dsm_4304 Archaeoglobus fulgidus dsm 4304]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONS OCA].

	==See Also==		==See Also==

OCA at 03:02, 26 July 2012

2012-07-26T03:02:01Z

← Older revision		Revision as of 03:02, 26 July 2012
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	[[Image:2ons.png\|left\|200px]]		[[Image:2ons.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2ons", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2ons\| PDB=2ons \| SCENE= }}		{{STRUCTURE_2ons\| PDB=2ons \| SCENE= }}

	===Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate===		===Crystal structure of A. fulgidus periplasmic binding protein ModA with bound tungstate===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17322901}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17322901 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_17322901}}		{{ABSTRACT_PUBMED_17322901}}

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	==See Also==		==See Also==
	*[[ABC transporter]]		*[[ABC transporter\|ABC transporter]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17322901~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017322901</ref><references group="xtra"/>
	[[Category: Archaeoglobus fulgidus dsm 4304]]		[[Category: Archaeoglobus fulgidus dsm 4304]]
	[[Category: Frei, D C.]]		[[Category: Frei, D C.]]