2orm - Revision history

OCA at 10:47, 30 August 2023

2023-08-30T10:47:27Z

← Older revision		Revision as of 10:47, 30 August 2023
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	<StructureSection load='2orm' size='340' side='right'caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2orm' size='340' side='right'caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Campylobacter_pylori_j99 Campylobacter~~ pylori ~~j99~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_J99 Helicobacter pylori J99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORM FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">dmpi (GI 7449587) ([https://www.ncbi.nlm.nih~~.~~gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=85963 Campylobacter pylori J99])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [https://pdbe.org/2orm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [https://www.ebi.ac.uk/pdbsum/2orm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [https://pdbe.org/2orm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [https://www.ebi.ac.uk/pdbsum/2orm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orm ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Y924_HELPY Y924_HELPY]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Campylobacter~~ pylori ~~j99~~]]		[[Category: Helicobacter pylori J99]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Almrud~~, J J~~]]		[[Category: Almrud JJ]]
	[[Category: Czerwinski~~, R M~~]]		[[Category: Czerwinski RM]]
	[[Category: Dasgupta, R]]		[[Category: Dasgupta R]]
	[[Category: Hackert~~, M L~~]]		[[Category: Hackert ML]]
	[[Category: Kern~~, A D~~]]		[[Category: Kern AD]]
	[[Category: Whitman~~, C P]]~~		[[Category: Whitman CP]]
	~~[[Category: 4-ot]]~~
	~~[[Category: 4-oxalocrotonate tautomerase homologue]]~~
	~~[[Category: Homohexamer]]~~
	~~[[Category: Isomerase~~]]

OCA at 13:04, 9 June 2021

2021-06-09T13:04:17Z

← Older revision		Revision as of 13:04, 9 June 2021
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	==Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.==		==Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.==
	<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2orm' size='340' side='right'caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Campylobacter_pylori_j99 Campylobacter pylori j99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ORM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_pylori_j99 Campylobacter pylori j99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ORM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [~~http~~://pdbe.org/2orm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2orm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2orm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [https://pdbe.org/2orm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [https://www.ebi.ac.uk/pdbsum/2orm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2orm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Campylobacter pylori j99]]		[[Category: Campylobacter pylori j99]]
			[[Category: Large Structures]]
	[[Category: Almrud, J J]]		[[Category: Almrud, J J]]
	[[Category: Czerwinski, R M]]		[[Category: Czerwinski, R M]]

OCA at 07:22, 22 August 2018

2018-08-22T07:22:47Z

← Older revision		Revision as of 07:22, 22 August 2018
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	==Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.==		==Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.==
	<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://pdbe.org/2orm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://pdbe.org/2orm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2orm ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2orm_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2orm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:38, 9 February 2016

2016-02-09T15:38:46Z

← Older revision		Revision as of 15:38, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2orm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:39, 10 September 2015

2015-09-10T23:39:37Z

← Older revision		Revision as of 23:39, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori Helicobacter~~ pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ORM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori_j99 Campylobacter pylori j99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ORM FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~210 Helicobacter~~ pylori])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85963 Campylobacter pylori J99])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://pdbe.org/2orm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2orm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Helicobacter~~ pylori]]		[[Category: Campylobacter pylori j99]]
	[[Category: Almrud, J J]]		[[Category: Almrud, J J]]
	[[Category: Czerwinski, R M]]		[[Category: Czerwinski, R M]]

OCA at 15:50, 19 January 2015

2015-01-19T15:50:54Z

← Older revision		Revision as of 15:50, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ORM FirstGlance]. <br>		<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ORM FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Almrud, J J.]]		[[Category: Almrud, J J]]
	[[Category: Czerwinski, R M.]]		[[Category: Czerwinski, R M]]
	[[Category: Dasgupta, R.]]		[[Category: Dasgupta, R]]
	[[Category: Hackert, M L.]]		[[Category: Hackert, M L]]
	[[Category: Kern, A D.]]		[[Category: Kern, A D]]
	[[Category: Whitman, C P.]]		[[Category: Whitman, C P]]
	[[Category: 4-ot]]		[[Category: 4-ot]]
	[[Category: 4-oxalocrotonate tautomerase homologue]]		[[Category: 4-oxalocrotonate tautomerase homologue]]
	[[Category: Homohexamer]]		[[Category: Homohexamer]]
	[[Category: Isomerase]]		[[Category: Isomerase]]

OCA at 18:59, 30 September 2014

2014-09-30T18:59:07Z

← Older revision		Revision as of 18:59, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2orm~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.==
			<StructureSection load='2orm' size='340' side='right' caption='[[2orm]], [[Resolution\|resolution]] 2.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ORM FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1bjp\|1bjp]], [[1gyj\|1gyj]], [[1aag\|1aag]], [[2op8\|2op8]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">dmpi (GI 7449587) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2orm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2orm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2orm RCSB], [http://www.ebi.ac.uk/pdbsum/2orm PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/or/2orm_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The tautomerase superfamily consists of structurally homologous proteins that are characterized by a beta-alpha-beta fold and a catalytic amino-terminal proline. 4-Oxalocrotonate tautomerase (4-OT) family members have been identified and categorized into five subfamilies on the basis of multiple sequence alignments and the conservation of key catalytic and structural residues. Representative members from two subfamilies have been cloned, expressed, purified, and subjected to kinetic and structural characterization. The crystal structure of DmpI from Helicobacter pylori (HpDmpI), a 4-OT homolog in subfamily 3, has been determined to high resolution (1.8A and 2.1A) in two different space groups. HpDmpI is a homohexamer with an active site cavity that includes Pro-1, but lacks the equivalent of Arg-11 and Arg-39 found in 4-OT. Instead, the side chain of Lys-36 replaces that of Arg-11 in a manner similar to that observed in the trimeric macrophage migration inhibitory factor (MIF), which is the title protein of another family in the superfamily. The electrostatic surface of the active site is also quite different and suggests that HpDmpI might prefer small, monoacid substrates. A kinetic analysis of the enzyme is consistent with the structural analysis, but a biological role for the enzyme remains elusive. The crystal structure of DmpI from Archaeoglobus fulgidus (AfDmpI), a 4-OT homolog in subfamily-4, has been determined to 2.4A resolution. AfDmpI is also a homohexamer, with a proposed active site cavity that includes Pro-1, but lacks any other residues that are readily identified as catalytic ones related to 4-OT activity. Indeed, the electrostatic potential of the active site differs significantly in that it is mostly neutral, in contrast to the usual electropositive features found in other 4-OT family members, suggesting that AfDmpI might accommodate hydrophobic substrates. A kinetic analysis has been carried out, but does not provide any clues about the type of reaction the enzyme might catalyze.

	~~{{STRUCTURE_2orm\| PDB=2orm \| SCENE= }}~~		Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.,Almrud JJ, Dasgupta R, Czerwinski RM, Kern AD, Hackert ML, Whitman CP Bioorg Chem. 2010 Jul 18. PMID:20709352<ref>PMID:20709352</ref>

	~~===Crystal Structure~~ of the ~~4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori~~.~~===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_20709352}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2orm]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org~~/~~wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:020709352<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Helicobacter pylori]]		[[Category: Helicobacter pylori]]
	[[Category: Almrud, J J.]]		[[Category: Almrud, J J.]]

OCA: Protected "2orm" [edit=sysop:move=sysop]

2013-01-07T11:18:03Z

Protected "2orm" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:18, 7 January 2013
(No difference)

OCA at 11:18, 7 January 2013

2013-01-07T11:18:00Z

← Older revision		Revision as of 11:18, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2orm.png\|left\|200px]]		[[Image:2orm.png\|left\|200px]]

	~~<!--~~
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	{{STRUCTURE_2orm\| PDB=2orm \| SCENE= }}		{{STRUCTURE_2orm\| PDB=2orm \| SCENE= }}

	===Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.===		===Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_20709352}}, adds the Publication Abstract to the page~~
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	{{ABSTRACT_PUBMED_20709352}}		{{ABSTRACT_PUBMED_20709352}}

	==About this Structure==		==About this Structure==
	~~2ORM~~ is a 6 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori_j99~~ Helicobacter pylori ~~j99~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA].		[[2orm]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20709352~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020709352</ref><references group="xtra"/>
	[[Category: Helicobacter pylori ~~j99~~]]		[[Category: Helicobacter pylori]]
	[[Category: Almrud, J J.]]		[[Category: Almrud, J J.]]
	[[Category: Czerwinski, R M.]]		[[Category: Czerwinski, R M.]]
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	[[Category: Homohexamer]]		[[Category: Homohexamer]]
	[[Category: Isomerase]]		[[Category: Isomerase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:27:09 2010''~~

OCA at 05:19, 1 September 2010

2010-09-01T05:19:03Z

← Older revision		Revision as of 05:19, 1 September 2010
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	===Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.===		===Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_20709352}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 20709352 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20709352}}

	==About this Structure==		==About this Structure==
	2ORM is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/~~Helicobacter_pylori~~ Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA].		2ORM is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Helicobacter_pylori_j99 Helicobacter pylori j99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ORM OCA].
	[[Category: Helicobacter pylori]]
			==Reference==
			<ref group="xtra">PMID:20709352</ref><references group="xtra"/>
			[[Category: Helicobacter pylori j99]]
	[[Category: Almrud, J J.]]		[[Category: Almrud, J J.]]
	[[Category: Czerwinski, R M.]]		[[Category: Czerwinski, R M.]]
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	[[Category: Isomerase]]		[[Category: Isomerase]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Feb 17 10~~:53:~~31 2009~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:27:09 2010''