2pfc - Revision history

OCA at 05:25, 17 October 2024

2024-10-17T05:25:41Z

← Older revision		Revision as of 05:25, 17 October 2024
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	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/~~FCOT_MYCTU FCOT_MYCTU~~] ~~Thiesterase~~ that ~~shows~~ a preference for long chain fatty acyl groups~~. In~~ vitro, cleaves the thioester linkage of palmitoyl-CoA, stearoyl-CoA, lauroyl-CoA and hexanoyl-CoA (PubMed:17524985). Contains low levels of trans-enoyl hydratase activity (PubMed:19136596).<ref>PMID:17524985</ref> <ref>PMID:19136596</ref>		[https://www.uniprot.org/uniprot/INLPD_MYCTU INLPD_MYCTU] Involved in the biosynthesis of a unique class of isonitrile lipopeptides (INLPs) that seem to function as virulence factors in M.tuberculosis and to play a role in metal acquisition (PubMed:28634299). Catalyzes a Michael addition of glycine to the beta-position of an alpha,beta-unsaturated fatty acyl-[ACP], producing a (3R)-3-[(carboxymethyl)amino]fatty acid. Acts on the (2E)-decenoyl moiety loaded on the acyl-carrier protein (ACP) Rv0100, forming the product (3R)-3-[(carboxymethyl)amino]decanoate released from the ACP (By similarity). Displays thioesterase activity with a preference for long chain fatty acyl groups; in vitro, cleaves the thioester linkage of palmitoyl-CoA, stearoyl-CoA, lauroyl-CoA and hexanoyl-CoA (PubMed:17524985). Contains low levels of trans-enoyl hydratase activity (PubMed:19136596).[UniProtKB:B2HKM2]<ref>PMID:17524985</ref> <ref>PMID:19136596</ref> <ref>PMID:28634299</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:39, 13 December 2023

2023-12-13T16:39:52Z

← Older revision		Revision as of 16:39, 13 December 2023
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	<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus~~ tuberculosis~~" (zopf 1883) klein 1884~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [https://pdbe.org/2pfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [https://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [https://pdbe.org/2pfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [https://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/FCOT_MYCTU FCOT_MYCTU] Thiesterase that shows a preference for long chain fatty acyl groups. In vitro, cleaves the thioester linkage of palmitoyl-CoA, stearoyl-CoA, lauroyl-CoA and hexanoyl-CoA (PubMed:17524985). Contains low levels of trans-enoyl hydratase activity (PubMed:19136596).<ref>PMID:17524985</ref> <ref>PMID:19136596</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Sacchettini, J C~~]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: ~~Wang, F~~]]		[[Category: Sacchettini JC]]
	[[Category: ~~Thioesterase]]~~		[[Category: Wang F]]
	~~[[Category: Tuberculosis]]~~
	~~[[Category: Unknown function]]~~
	~~[[Category: Virulence~~]]

OCA at 07:45, 9 March 2022

2022-03-09T07:45:13Z

← Older revision		Revision as of 07:45, 9 March 2022
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	<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [~~http~~://pdbe.org/2pfc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [https://pdbe.org/2pfc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [https://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:54, 3 June 2020

2020-06-03T06:54:47Z

← Older revision		Revision as of 06:54, 3 June 2020
Line 1:		Line 1:

	==Structure of Mycobacterium tuberculosis Rv0098==		==Structure of Mycobacterium tuberculosis Rv0098==
	<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2pfc' size='340' side='right'caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PFC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://pdbe.org/2pfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://pdbe.org/2pfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Sacchettini, J C]]		[[Category: Sacchettini, J C]]
	[[Category: Wang, F]]		[[Category: Wang, F]]

OCA at 08:26, 29 August 2018

2018-08-29T08:26:48Z

← Older revision		Revision as of 08:26, 29 August 2018
Line 1:		Line 1:

	==Structure of Mycobacterium tuberculosis Rv0098==		==Structure of Mycobacterium tuberculosis Rv0098==
	<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://pdbe.org/2pfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://pdbe.org/2pfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pfc ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 21:54, 11 September 2015

2015-09-11T21:54:21Z

← Older revision		Revision as of 21:54, 11 September 2015
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	<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mycobacterium_tuberculosis Mycobacterium~~ tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://pdbe.org/2pfc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2pfc" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Mycobacterium tuberculosis]]~~
	[[Category: Sacchettini, J C]]		[[Category: Sacchettini, J C]]
	[[Category: Wang, F]]		[[Category: Wang, F]]

OCA at 20:05, 25 December 2014

2014-12-25T20:05:55Z

← Older revision		Revision as of 20:05, 25 December 2014
Line 19:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Sacchettini, J C.]]		[[Category: Sacchettini, J C]]
	[[Category: Wang, F.]]		[[Category: Wang, F]]
	[[Category: Thioesterase]]		[[Category: Thioesterase]]
	[[Category: Tuberculosis]]		[[Category: Tuberculosis]]
	[[Category: Unknown function]]		[[Category: Unknown function]]
	[[Category: Virulence]]		[[Category: Virulence]]

OCA at 11:26, 20 October 2014

2014-10-20T11:26:59Z

← Older revision		Revision as of 11:26, 20 October 2014
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	[[~~Image~~:2pfc.~~png\|left\|200px~~]]		==Structure of Mycobacterium tuberculosis Rv0098==
			<StructureSection load='2pfc' size='340' side='right' caption='[[2pfc]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PFC FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pfc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pfc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pfc RCSB], [http://www.ebi.ac.uk/pdbsum/2pfc PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Rv0098 is part of an operon, Rv0096-Rv0101, from Mycobacterium tuberculosis (Mtb) that is essential for Mtb's survival in mouse macrophages. This operon also contains an acyl carrier protein and one of the only two nonribosomal peptide synthases in Mtb. Rv0098 is annotated in the genome as a hypothetical protein and was proposed to be an acyl-coenzyme A (CoA) dehydratase. The structure of Rv0098, together with subsequent biochemical analysis, indicated that Rv0098 is a long-chain fatty acyl-CoA thioesterase (FcoT). However, FcoT lacks a general base or a nucleophile that is always found in the catalytic site of type II and type I thioesterases, respectively. The active site of Mtb FcoT reveals the structural basis for its substrate specificity for long-chain acyl-CoA and allows us to propose a catalytic mechanism for the enzyme. The characterization of Mtb FcoT provides a putative function of this operon that is crucial for Mtb pathogenicity.

	~~{{STRUCTURE_2pfc\| PDB=2pfc \| SCENE= }}~~		Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence.,Wang F, Langley R, Gulten G, Wang L, Sacchettini JC Chem Biol. 2007 May;14(5):543-51. PMID:17524985<ref>PMID:17524985</ref>

	~~===Structure~~ of ~~Mycobacterium tuberculosis Rv0098===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17524985}}~~		== References ==
			<references/>
	==~~About this Structure~~==		__TOC__
	~~[[2pfc]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA].~~		</StructureSection>
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	[[Category: Sacchettini, J C.]]		[[Category: Sacchettini, J C.]]

OCA: Protected "2pfc" [edit=sysop:move=sysop]

2013-01-07T11:38:11Z

Protected "2pfc" [edit=sysop:move=sysop]

← Older revision	Revision as of 11:38, 7 January 2013
(No difference)

OCA at 11:38, 7 January 2013

2013-01-07T11:38:08Z

← Older revision		Revision as of 11:38, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2pfc.png\|left\|200px]]		[[Image:2pfc.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2pfc", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2pfc\| PDB=2pfc \| SCENE= }}		{{STRUCTURE_2pfc\| PDB=2pfc \| SCENE= }}

	===Structure of Mycobacterium tuberculosis Rv0098===		===Structure of Mycobacterium tuberculosis Rv0098===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17524985}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17524985 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_17524985}}		{{ABSTRACT_PUBMED_17524985}}

	==About this Structure==		==About this Structure==
	~~2PFC is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA].		[[2pfc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PFC OCA].

	~~==Reference==~~
	Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence., Wang F, Langley R, Gulten G, Wang L, Sacchettini JC, Chem Biol. 2007 May;14(5):543-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17524985 17524985]
	[[Category: Mycobacterium tuberculosis]]		[[Category: Mycobacterium tuberculosis]]
	~~[[Category: Single protein]]~~
	[[Category: Sacchettini, J C.]]		[[Category: Sacchettini, J C.]]
	[[Category: Wang, F.]]		[[Category: Wang, F.]]
Line 32:		Line 16:
	[[Category: Unknown function]]		[[Category: Unknown function]]
	[[Category: Virulence]]		[[Category: Virulence]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 21:23:22 2008''~~