2phy - Revision history

OCA at 22:28, 26 March 2025

2025-03-26T22:28:02Z

← Older revision		Revision as of 22:28, 26 March 2025
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	<StructureSection load='2phy' size='340' side='right'caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2phy' size='340' side='right'caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [https://pdbe.org/2phy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [https://www.ebi.ac.uk/pdbsum/2phy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2phy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [https://pdbe.org/2phy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [https://www.ebi.ac.uk/pdbsum/2phy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2phy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA]] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.		[https://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phy_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	[[Category: Halorhodospira halophila]]		[[Category: Halorhodospira halophila]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Borgstahl~~, G E.O~~]]		[[Category: Borgstahl GEO]]
	[[Category: Getzoff~~, E D]]~~		[[Category: Getzoff ED]]
	~~[[Category: Light sensor for negative phototaxis]]~~
	~~[[Category: Photoreceptor~~]]

OCA at 20:52, 20 October 2021

2021-10-20T20:52:06Z

← Older revision		Revision as of 20:52, 20 October 2021
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	<StructureSection load='2phy' size='340' side='right'caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2phy' size='340' side='right'caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [~~http~~://pdbe.org/2phy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2phy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2phy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [https://pdbe.org/2phy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [https://www.ebi.ac.uk/pdbsum/2phy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2phy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA]] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.		[[https://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA]] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 14:24, 18 December 2019

2019-12-18T14:24:25Z

← Older revision		Revision as of 14:24, 18 December 2019
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	==PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)==		==PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)==
	<StructureSection load='2phy' size='340' side='right' caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2phy' size='340' side='right'caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phy_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phy_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</StructureSection>		</StructureSection>
	[[Category: Halorhodospira halophila]]		[[Category: Halorhodospira halophila]]
			[[Category: Large Structures]]
	[[Category: Borgstahl, G E.O]]		[[Category: Borgstahl, G E.O]]
	[[Category: Getzoff, E D]]		[[Category: Getzoff, E D]]
	[[Category: Light sensor for negative phototaxis]]		[[Category: Light sensor for negative phototaxis]]
	[[Category: Photoreceptor]]		[[Category: Photoreceptor]]

OCA at 07:10, 29 November 2017

2017-11-29T07:10:26Z

← Older revision		Revision as of 07:10, 29 November 2017
Line 1:		Line 1:

	==PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)==		==PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)==
	<StructureSection load='2phy' size='340' side='right' caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='2phy' size='340' side='right' caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>
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	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://pdbe.org/2phy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://pdbe.org/2phy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2phy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 23:45, 7 February 2016

2016-02-07T23:45:59Z

← Older revision		Revision as of 23:45, 7 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2phy ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:57, 10 September 2015

2015-09-10T05:57:44Z

← Older revision		Revision as of 05:57, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://pdbe.org/2phy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PYP_HALHA PYP_HALHA]] Photoactive blue light protein. Probably functions as a photoreceptor for a negative phototaxis response.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2phy" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:07, 19 January 2015

2015-01-19T17:07:47Z

← Older revision		Revision as of 17:07, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Halorhodospira halophila]]		[[Category: Halorhodospira halophila]]
	[[Category: Borgstahl, G E.O.]]		[[Category: Borgstahl, G E.O]]
	[[Category: Getzoff, E D.]]		[[Category: Getzoff, E D]]
	[[Category: Light sensor for negative phototaxis]]		[[Category: Light sensor for negative phototaxis]]
	[[Category: Photoreceptor]]		[[Category: Photoreceptor]]

OCA at 19:41, 30 September 2014

2014-09-30T19:41:40Z

← Older revision		Revision as of 19:41, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2phy~~.~~png~~\|~~left~~\|~~200px~~]]		==PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)==
			<StructureSection load='2phy' size='340' side='right' caption='[[2phy]], [[Resolution\|resolution]] 1.40Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PHY FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HC4:4-HYDROXYCINNAMIC+ACID'>HC4</scene><br>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2phy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2phy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2phy RCSB], [http://www.ebi.ac.uk/pdbsum/2phy PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/2phy_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			A photosensing protein directs light energy captured by its chromophore into a photocycle. The protein's structure must accommodate the photocycle and promote the resulting chemical or conformational changes that lead to signal transduction. The 1.4 A crystallographic structure of photoactive yellow protein, determined by multiple isomorphous replacement methods, provides the first view at atomic resolution of a protein with a photocycle. The alpha/beta fold, which differs from the original chain tracing, shows striking similarity to distinct parts of the signal transduction proteins profilin and the SH2 domain. In the dark state structure of photoactive yellow protein, the novel 4-hydroxycinnamyl chromophore, covalently attached to Cys69, is buried within the major hydrophobic core of the protein and is tethered at both ends by hydrogen bonds. In the active site, the yellow anionic form of the chromophore is stabilized by hydrogen bonds from the side chains of Tyr42 and buried Glu46 to the phenolic oxygen atom and by electrostatic complementarity with the positively charged guanidinium group of Arg52. Thr50 further interlocks Tyr42, Glu46, and Arg52 through a network of active site hydrogen bonds. Arg52, located in a concavity of the protein surface adjacent to the dominant patch of negative electrostatic potential, shields the chromophore from solvent and is positioned to form a gateway for the phototactic signal. Overall, the high-resolution structure of photoactive yellow protein supports a mechanism whereby electrostatic interactions create an active site poised for photon-induced rearrangements and efficient protein-mediated signal transduction.

	~~{{STRUCTURE_2phy\| PDB=2phy \| SCENE= }}~~		1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore.,Borgstahl GE, Williams DR, Getzoff ED Biochemistry. 1995 May 16;34(19):6278-87. PMID:7756254<ref>PMID:7756254</ref>

	~~===PHOTOACTIVE YELLOW PROTEIN~~, ~~DARK STATE (UNBLEACHED)===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_7756254}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2phy]] is~~ a ~~1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes~~ the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:007756254<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Halorhodospira halophila]]		[[Category: Halorhodospira halophila]]
	[[Category: Borgstahl, G E.O.]]		[[Category: Borgstahl, G E.O.]]

OCA: Protected "2phy" [edit=sysop:move=sysop]

2013-01-07T12:04:23Z

Protected "2phy" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:04, 7 January 2013
(No difference)

OCA at 12:04, 7 January 2013

2013-01-07T12:04:20Z

← Older revision		Revision as of 12:04, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2phy.png\|left\|200px]]		[[Image:2phy.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2phy", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2phy\| PDB=2phy \| SCENE= }}		{{STRUCTURE_2phy\| PDB=2phy \| SCENE= }}

	===PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)===		===PHOTOACTIVE YELLOW PROTEIN, DARK STATE (UNBLEACHED)===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_7756254}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 7756254 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_7756254}}		{{ABSTRACT_PUBMED_7756254}}

	==About this Structure==		==About this Structure==
	~~2PHY~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA].		[[2phy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Halorhodospira_halophila Halorhodospira halophila]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1phy 1phy]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PHY OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~7756254~~</ref><references group="xtra"/>		<ref group="xtra">PMID:007756254</ref><references group="xtra"/>
	[[Category: Halorhodospira halophila]]		[[Category: Halorhodospira halophila]]
	[[Category: Borgstahl, G E.O.]]		[[Category: Borgstahl, G E.O.]]
	[[Category: Getzoff, E D.]]		[[Category: Getzoff, E D.]]
	[[Category: Light sensor for negative phototaxis]]		[[Category: Light sensor for negative phototaxis]]
			[[Category: Photoreceptor]]
	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 17:17:07 2009''~~