2plb - Revision history

OCA at 11:04, 30 August 2023

2023-08-30T11:04:09Z

← Older revision		Revision as of 11:04, 30 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PLB FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SPM:SPERMINE'>SPM</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [https://pdbe.org/2plb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [https://www.ebi.ac.uk/pdbsum/2plb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [https://pdbe.org/2plb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [https://www.ebi.ac.uk/pdbsum/2plb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>
	</table>		</table>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Fourme, R]]		[[Category: Fourme R]]
	[[Category: Girard, E]]		[[Category: Girard E]]
	[[Category: Kahn, R]]		[[Category: Kahn R]]
	[[Category: Prange, T]]		[[Category: Prange T]]
	~~[[Category: Dna]]~~
	~~[[Category: High-pressure~~]]

OCA at 07:46, 9 March 2022

2022-03-09T07:46:18Z

← Older revision		Revision as of 07:46, 9 March 2022
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	<StructureSection load='2plb' size='340' side='right'caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2plb' size='340' side='right'caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2PLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PLB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [~~http~~://pdbe.org/2plb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2plb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [https://pdbe.org/2plb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [https://www.ebi.ac.uk/pdbsum/2plb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:56, 3 June 2020

2020-06-03T06:56:08Z

← Older revision		Revision as of 06:56, 3 June 2020
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	==D(GTATACC) under hydrostatic pressure of 1.39 GPa==		==D(GTATACC) under hydrostatic pressure of 1.39 GPa==
	<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2plb' size='340' side='right'caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PLB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://pdbe.org/2plb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://pdbe.org/2plb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Fourme, R]]		[[Category: Fourme, R]]
	[[Category: Girard, E]]		[[Category: Girard, E]]

OCA at 09:03, 29 August 2018

2018-08-29T09:03:23Z

← Older revision		Revision as of 09:03, 29 August 2018
Line 1:		Line 1:

	==D(GTATACC) under hydrostatic pressure of 1.39 GPa==		==D(GTATACC) under hydrostatic pressure of 1.39 GPa==
	<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://pdbe.org/2plb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://pdbe.org/2plb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2plb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:44, 12 September 2015

2015-09-12T02:44:00Z

← Older revision		Revision as of 02:44, 12 September 2015
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://pdbe.org/2plb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2plb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 23:25, 3 January 2015

2015-01-03T23:25:36Z

← Older revision		Revision as of 23:25, 3 January 2015
Line 2:		Line 2:
	<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. <br>		<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PLB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>
	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>
	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>		</table>
	<table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 13:
	Adaptation of the base-paired double-helix molecular architecture to extreme pressure.,Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:17617642<ref>PMID:17617642</ref>		Adaptation of the base-paired double-helix molecular architecture to extreme pressure.,Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:17617642<ref>PMID:17617642</ref>

	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 20:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Fourme, R.]]		[[Category: Fourme, R]]
	[[Category: Girard, E.]]		[[Category: Girard, E]]
	[[Category: Kahn, R.]]		[[Category: Kahn, R]]
	[[Category: Prange, T.]]		[[Category: Prange, T]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: High-pressure]]		[[Category: High-pressure]]

OCA at 08:44, 7 May 2014

2014-05-07T08:44:34Z

← Older revision		Revision as of 08:44, 7 May 2014
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	[[~~Image~~:~~2plb~~.~~png~~\|~~left~~\|~~200px~~]]		==D(GTATACC) under hydrostatic pressure of 1.39 GPa==
			<StructureSection load='2plb' size='340' side='right' caption='[[2plb]], [[Resolution\|resolution]] 1.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SPM:SPERMINE'>SPM</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[115d\|115d]], [[1vj4\|1vj4]], [[2pkv\|2pkv]], [[2pl4\|2pl4]], [[2pl8\|2pl8]], [[2plo\|2plo]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2plb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2plb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2plb RCSB], [http://www.ebi.ac.uk/pdbsum/2plb PDBsum]</span></td></tr>
			<table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The behaviour of the d(GGTATACC) oligonucleotide has been investigated by X-ray crystallography at 295 K in the range from ambient pressure to 2 GPa (approximately 20,000 atm). Four 3D-structures of the A-DNA form (at ambient pressure, 0.55, 1.09 and 1.39 GPa) were refined at 1.60 or 1.65 A resolution. In addition to the diffraction pattern of the A-form, the broad meridional streaks previously explained by occluded B-DNA octamers within the channels of the crystalline A-form matrix were observed up to at least 2 GPa. This work highlights an important property of nucleic acids, their capability to withstand very high pressures, while keeping in such conditions a nearly invariant geometry of base pairs that store and carry genetic information. The double-helix base-paired architecture behaves as a molecular spring, which makes it especially adapted to very harsh conditions. These features may have contributed to the emergence of a RNA World at prebiotic stage.

	<!--		Adaptation of the base-paired double-helix molecular architecture to extreme pressure.,Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:17617642<ref>PMID:17617642</ref>
	~~The line below this paragraph~~, ~~containing "STRUCTURE_2plb"~~, ~~creates the "Structure Box" on the page~~.
	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display~~.
	-->
	~~{{STRUCTURE_2plb\| PDB=2plb \| SCENE= }}~~

	~~===D(GTATACC) under hydrostatic pressure~~ of ~~1.39 GPa===~~		From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
			</div>
			== References ==
	~~<!--~~		<references/>
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17617642}}, adds the Publication Abstract to~~ the ~~page~~		__TOC__
	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 17617642 is the PubMed ID number~~.		</StructureSection>
	-->
	~~{{ABSTRACT_PUBMED_17617642}}~~

	~~==About this Structure==~~
	~~[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA].~~

	==~~Reference~~==
	<~~ref group="xtra">PMID:017617642<~~/~~ref><ref group="xtra">PMID:002911354</ref><ref group="xtra">PMID:011524565</ref~~><~~ref group="xtra">PMID:016478683</ref><references group="xtra"~~/>
	[[Category: Fourme, R.]]		[[Category: Fourme, R.]]
	[[Category: Girard, E.]]		[[Category: Girard, E.]]

OCA at 07:10, 22 February 2012

2012-02-22T07:10:43Z

← Older revision		Revision as of 07:10, 22 February 2012
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	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17617642~~</ref><ref group="xtra">PMID:~~2911354~~</ref><ref group="xtra">PMID:~~11524565~~</ref><ref group="xtra">PMID:~~16478683~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017617642</ref><ref group="xtra">PMID:002911354</ref><ref group="xtra">PMID:011524565</ref><ref group="xtra">PMID:016478683</ref><references group="xtra"/>
	[[Category: Fourme, R.]]		[[Category: Fourme, R.]]
	[[Category: Girard, E.]]		[[Category: Girard, E.]]
	[[Category: Kahn, R.]]		[[Category: Kahn, R.]]
	[[Category: Prange, T.]]		[[Category: Prange, T.]]
	~~[[Category: Crystal structure]]~~
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: High-pressure]]		[[Category: High-pressure]]

OCA: Protected "2plb" [edit=sysop:move=sysop]

2011-03-15T00:48:13Z

Protected "2plb" [edit=sysop:move=sysop]

← Older revision	Revision as of 00:48, 15 March 2011
(No difference)

OCA at 00:48, 15 March 2011

2011-03-15T00:48:12Z

← Older revision		Revision as of 00:48, 15 March 2011
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	~~{{Seed}}~~
	[[Image:2plb.png\|left\|200px]]		[[Image:2plb.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA].		[[2plb]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PLB OCA].

	==Reference==		==Reference==
	Adaptation of the base-paired double-helix molecular architecture to extreme pressure., Girard E, Prange T, Dhaussy AC, Migianu-Griffoni E, Lecouvey M, Chervin JC, Mezouar M, Kahn R, Fourme R, Nucleic Acids Res. 2007;35(14):4800-8. Epub 2007 Jul 7. PMID:~~[http:~~/~~/www.ncbi.nlm.nih.gov/pubmed/17617642 17617642]~~		<ref group="xtra">PMID:17617642</ref><ref group="xtra">PMID:2911354</ref><ref group="xtra">PMID:11524565</ref><ref group="xtra">PMID:16478683</ref><references group="xtra"/>

	~~Coexistence of A- and B-form DNA in a single crystal lattice., Doucet J, Benoit JP, Cruse WB, Prange T, Kennard O, Nature. 1989 Jan 12;337(6203):190-2.~~ PMID:~~[http://www.ncbi.nlm.nih.gov/pubmed~~/~~2911354 2911354]~~

	High-pressure protein crystallography (HPPX): instrumentation, methodology and results on lysozyme crystals., Fourme R, Kahn R, Mezouar M, Girard E, Hoerentrup C, Prange T, Ascone I, J Synchrotron Radiat. 2001 Sep 1;8(Pt 5):1149-56. Epub 2001 Aug 28. PMID:~~[http://www.ncbi.nlm.nih.gov/pubmed~~/~~11524565 11524565]~~

	High pressure macromolecular crystallography: the 140-MPa crystal structure at 2.3 A resolution of urate oxidase, a 135-kDa tetrameric assembly., Colloc'h N, Girard E, Dhaussy AC, Kahn R, Ascone I, Mezouar M, Fourme R, Biochim Biophys Acta. 2006 Mar;1764(3):391-7. Epub 2006 Jan 26. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~16478683 16478683]~~
	[[Category: Fourme, R.]]		[[Category: Fourme, R.]]
	[[Category: Girard, E.]]		[[Category: Girard, E.]]
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	[[Category: Dna]]		[[Category: Dna]]
	[[Category: High-pressure]]		[[Category: High-pressure]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:40:50 2008''~~