2ps3 - Revision history

OCA at 01:19, 21 November 2024

2024-11-21T01:19:37Z

← Older revision		Revision as of 01:19, 21 November 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2ps3_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2ps3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 11:07, 30 August 2023

2023-08-30T11:07:56Z

← Older revision		Revision as of 11:07, 30 August 2023
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	<StructureSection load='2ps3' size='340' side='right'caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='2ps3' size='340' side='right'caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[2osv\|2osv]]~~, [[~~2ogw~~\|~~2ogw~~]]~~, [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</div>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.47Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [https://pdbe.org/2ps3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ps3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ps3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [https://pdbe.org/2ps3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ps3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ps3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.		[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Kim~~, L R~~]]		[[Category: Kim LR]]
	[[Category: Rosenzweig~~, A C~~]]		[[Category: Rosenzweig AC]]
	[[Category: Vorontsov~~, I I~~]]		[[Category: Vorontsov II]]
	[[Category: Yatsunyk~~, L A]]~~		[[Category: Yatsunyk LA]]
	~~[[Category: Metal transport~~]]

OCA at 15:31, 17 June 2021

2021-06-17T15:31:34Z

← Older revision		Revision as of 15:31, 17 June 2021
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	<StructureSection load='2ps3' size='340' side='right'caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='2ps3' size='340' side='right'caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [~~http~~://pdbe.org/2ps3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ps3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ps3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [https://pdbe.org/2ps3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [https://www.ebi.ac.uk/pdbsum/2ps3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ps3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.		[[https://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:54, 31 July 2019

2019-07-31T07:54:36Z

← Older revision		Revision as of 07:54, 31 July 2019
Line 1:		Line 1:

	==Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli==		==Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli==
	<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='2ps3' size='340' side='right'caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2ps3_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2ps3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Kim, L R]]		[[Category: Kim, L R]]
	[[Category: Rosenzweig, A C]]		[[Category: Rosenzweig, A C]]

OCA at 09:32, 18 October 2017

2017-10-18T09:32:30Z

← Older revision		Revision as of 09:32, 18 October 2017
Line 1:		Line 1:

	==Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli==		==Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli==
	<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
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	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://pdbe.org/2ps3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://pdbe.org/2ps3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ps3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 19:03, 8 February 2016

2016-02-08T19:03:45Z

← Older revision		Revision as of 19:03, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ps3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:30, 10 September 2015

2015-09-10T14:30:34Z

← Older revision		Revision as of 14:30, 10 September 2015
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	<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>		<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://pdbe.org/2ps3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ps3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Kim, L R]]		[[Category: Kim, L R]]
	[[Category: Rosenzweig, A C]]		[[Category: Rosenzweig, A C]]

OCA at 01:30, 25 December 2014

2014-12-25T01:30:50Z

← Older revision		Revision as of 01:30, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/ZNUA_ECOLI ZNUA_ECOLI]] Involved in the high-affinity zinc uptake transport system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kim, L R.]]		[[Category: Kim, L R]]
	[[Category: Rosenzweig, A C.]]		[[Category: Rosenzweig, A C]]
	[[Category: Vorontsov, I I.]]		[[Category: Vorontsov, I I]]
	[[Category: Yatsunyk, L A.]]		[[Category: Yatsunyk, L A]]
	[[Category: Metal transport]]		[[Category: Metal transport]]

OCA at 19:01, 30 September 2014

2014-09-30T19:01:41Z

← Older revision		Revision as of 19:01, 30 September 2014
Line 1:		Line 1:
	[[Image:~~2ps3~~.~~png~~\|~~left~~\|~~200px~~]]		==Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli==
			<StructureSection load='2ps3' size='340' side='right' caption='[[2ps3]], [[Resolution\|resolution]] 2.47Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2ps3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PS3 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2osv\|2osv]], [[2ogw\|2ogw]], [[2prs\|2prs]], [[2ps0\|2ps0]], [[2ps9\|2ps9]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ps3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ps3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ps3 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ps/2ps3_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			ZnuA is the periplasmic Zn(2+)-binding protein associated with the high-affinity ATP-binding cassette ZnuABC transporter from Escherichia coli. Although several structures of ZnuA and its homologs have been determined, details regarding metal ion stoichiometry, affinity, and specificity as well as the mechanism of metal uptake and transfer remain unclear. The crystal structures of E. coli ZnuA (Eco-ZnuA) in the apo, Zn(2+)-bound, and Co(2+)-bound forms have been determined. ZnZnuA binds at least two metal ions. The first, observed previously in other structures, is coordinated tetrahedrally by Glu59, His60, His143, and His207. Replacement of Zn(2+) with Co(2+) results in almost identical coordination geometry at this site. The second metal binding site involves His224 and several yet to be identified residues from the His-rich loop that is unique to Zn(2+) periplasmic metal binding receptors. Electron paramagnetic resonance and X-ray absorption spectroscopic data on CoZnuA provide additional insight into possible residues involved in this second site. The second site is also detected by metal analysis and circular dichroism (CD) titrations. Eco-ZnuA binds Zn(2+) (estimated K (d) < 20 nM), Co(2+), Ni(2+), Cu(2+), Cu(+), and Cd(2+), but not Mn(2+). Finally, conformational changes upon metal binding observed in the crystal structures together with fluorescence and CD data indicate that only Zn(2+) substantially stabilizes ZnuA and might facilitate recognition of ZnuB and subsequent metal transfer.

	~~{{STRUCTURE_2ps3\| PDB=2ps3 \| SCENE= }}~~		Structure and metal binding properties of ZnuA, a periplasmic zinc transporter from Escherichia coli.,Yatsunyk LA, Easton JA, Kim LR, Sugarbaker SA, Bennett B, Breece RM, Vorontsov II, Tierney DL, Crowder MW, Rosenzweig AC J Biol Inorg Chem. 2008 Feb;13(2):271-88. Epub 2007 Nov 20. PMID:18027003<ref>PMID:18027003</ref>

	~~===Structure and metal binding properties of ZnuA~~, a ~~periplasmic zinc transporter from Escherichia coli===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18027003}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2ps3]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2PS3 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:018027003<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Kim, L R.]]		[[Category: Kim, L R.]]

OCA: Protected "2ps3" [edit=sysop:move=sysop]

2013-01-07T13:58:27Z

Protected "2ps3" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:58, 7 January 2013
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