2pta - Revision history

OCA at 08:30, 30 October 2024

2024-10-30T08:30:09Z

← Older revision		Revision as of 08:30, 30 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
	</table>		</table>

OCA at 13:10, 26 July 2023

2023-07-26T13:10:27Z

← Older revision		Revision as of 13:10, 26 July 2023
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	==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==		==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
	<StructureSection load='2pta' size='340' side='right'caption='[[2pta~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>		<StructureSection load='2pta' size='340' side='right'caption='[[2pta]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Emperor_scorpion Emperor scorpion~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM]] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>		[https://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Emperor scorpion]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Blaustein, M P~~]]		[[Category: Pandinus imperator]]
	[[Category: ~~Collins, J H~~]]		[[Category: Blaustein MP]]
	[[Category: ~~Rogowski, R S~~]]		[[Category: Collins JH]]
	[[Category: ~~Tenenholz, T C~~]]		[[Category: Rogowski RS]]
	[[Category: ~~Weber, D J~~]]		[[Category: Tenenholz TC]]
	[[Category: ~~Alpha-k toxin family]]~~		[[Category: Weber DJ]]
	~~[[Category: Neurotoxin]]~~
	~~[[Category: Nmr solution structure]]~~
	~~[[Category: Potassium channel blocker]]~~
	~~[[Category: Scorpion toxin~~]]

OCA at 20:52, 20 October 2021

2021-10-20T20:52:46Z

← Older revision		Revision as of 20:52, 20 October 2021
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	<StructureSection load='2pta' size='340' side='right'caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2pta' size='340' side='right'caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [~~http~~://pdbe.org/2pta PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pta PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [https://pdbe.org/2pta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [https://www.ebi.ac.uk/pdbsum/2pta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM]] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>		[[https://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM]] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 14:17, 18 December 2019

2019-12-18T14:17:36Z

← Older revision		Revision as of 14:17, 18 December 2019
Line 1:		Line 1:

	==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==		==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
	<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2pta' size='340' side='right'caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 2pta" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2pta" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Potassium channel toxin 3D structures\|Potassium channel toxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Emperor scorpion]]		[[Category: Emperor scorpion]]
			[[Category: Large Structures]]
	[[Category: Blaustein, M P]]		[[Category: Blaustein, M P]]
	[[Category: Collins, J H]]		[[Category: Collins, J H]]

OCA at 07:11, 29 November 2017

2017-11-29T07:11:04Z

← Older revision		Revision as of 07:11, 29 November 2017
Line 1:		Line 1:

	==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==		==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
	<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [http://pdbe.org/2pta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [http://www.ebi.ac.uk/pdbsum/2pta PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [http://pdbe.org/2pta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [http://www.ebi.ac.uk/pdbsum/2pta PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pta ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 2pta" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 2pta" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Potassium channel toxin\|Potassium channel toxin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:09, 12 September 2015

2015-09-12T00:09:53Z

← Older revision		Revision as of 00:09, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pandinus_imperator Pandinus imperator~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Emperor_scorpion Emperor scorpion]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [http://www.ebi.ac.uk/pdbsum/2pta PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [http://pdbe.org/2pta PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [http://www.ebi.ac.uk/pdbsum/2pta PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/KAX71_PANIM KAX71_PANIM]] Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).<ref>PMID:8660410</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2pta" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 20:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Pandinus imperator~~]]		[[Category: Emperor scorpion]]
	[[Category: Blaustein, M P]]		[[Category: Blaustein, M P]]
	[[Category: Collins, J H]]		[[Category: Collins, J H]]

OCA at 14:02, 17 December 2014

2014-12-17T14:02:42Z

← Older revision		Revision as of 14:02, 17 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_2pta\| PDB=2pta \| SCENE= }}~~		==PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES==
	===PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES===		<StructureSection load='2pta' size='340' side='right' caption='[[2pta]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	~~{{ABSTRACT_PUBMED_9062103}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PTA FirstGlance]. <br>
			</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pta OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pta RCSB], [http://www.ebi.ac.uk/pdbsum/2pta PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			PiTX-K alpha, a 35-residue peptide recently isolated from the venom of Pandinus imperator, blocks the rapidly inactivating (A-type) K+ channel(s) in rat brain synaptosomes and the cloned Kv 1.2 potassium channel at very low toxin concentrations (6 nM and 32 pM, respectively) [Rogowski, R. S., Collins, J. H., O'Neil, T. J., Gustafson, T. A., Werkman, T. A., Rogawski, M. A., Tenenholz, T. C., Weber, D. J., & Blaustein, M. P. (1996) Mol. Pharmacol. 50, 1167-1177]. The three-dimensional structure of PiTX-K alpha was determined using NMR spectroscopy in order to understand its selectivity and affinity toward K+ channels. PiTX-K alpha was found to have an alpha-helix from residues 10 to 21 and two beta-strands (betaI, 26-28; betaII, 33-35) connected by a type II beta-turn to form a small antiparallel beta-sheet. Three disulfide bonds, which are conserved in all members of the charybdotoxin family (alpha-K toxins), anchor one face of the alpha-helix to the beta-sheet. The N-terminal portion of PiTX-K alpha has three fewer residues than other alpha-K toxins such as charybdotoxin. Rather than forming a third beta-strand as found for other alpha-K toxins, the N-terminal region of PiTX-K alpha adopts an extended conformation. This structural difference in PiTX-K alpha together with differences in sequence at Pro-10, Tyr-14, and Asn-25 (versus Ser-10, Trp-14, and Arg-25 in CTX) may explain why PiTX-K alpha does not block maxi-K+ channels. Differences in three-dimensional structure between PiTX-K alpha and charybdotoxin are also observed in both the tight turn and the loop that connects the first beta-strand to the alpha-helix. As a result, side chains of two residues (Tyr-23 and Arg-31) are in regions of PiTX-K alpha that probably interact with rapidly inactivating A-type K+ channels. The analogous residues in charybdotoxin are positioned differently on the toxin surface. Thus, the locations of Tyr-23 and Arg-31 side chains in PiTX-K alpha could explain why this toxin blocks A-type channels at much lower concentrations than does charybdotoxin.

	~~==About this Structure==~~		Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels.,Tenenholz TC, Rogowski RS, Collins JH, Blaustein MP, Weber DJ Biochemistry. 1997 Mar 11;36(10):2763-71. PMID:9062103<ref>PMID:9062103</ref>
	~~[[2pta]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pandinus_imperator Pandinus imperator]~~. ~~Full experimental information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2PTA OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[Potassium channel toxin\|Potassium channel toxin]]		*[[Potassium channel toxin\|Potassium channel toxin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:009062103<~~/~~ref~~><~~ref group="xtra">PMID:010631983</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Pandinus imperator]]		[[Category: Pandinus imperator]]
	[[Category: Blaustein, M P.]]		[[Category: Blaustein, M P]]
	[[Category: Collins, J H.]]		[[Category: Collins, J H]]
	[[Category: Rogowski, R S.]]		[[Category: Rogowski, R S]]
	[[Category: Tenenholz, T C.]]		[[Category: Tenenholz, T C]]
	[[Category: Weber, D J.]]		[[Category: Weber, D J]]
	[[Category: Alpha-k toxin family]]		[[Category: Alpha-k toxin family]]
	[[Category: Neurotoxin]]		[[Category: Neurotoxin]]

OCA at 09:30, 11 March 2013

2013-03-11T09:30:26Z

← Older revision		Revision as of 09:30, 11 March 2013
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	~~[[Image:2pta.png\|left\|200px]]~~

	{{STRUCTURE_2pta\| PDB=2pta \| SCENE= }}		{{STRUCTURE_2pta\| PDB=2pta \| SCENE= }}

	===PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES===		===PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES===

	{{ABSTRACT_PUBMED_9062103}}		{{ABSTRACT_PUBMED_9062103}}

	==About this Structure==		==About this Structure==
	[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA].		[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA].

			==See Also==
			*[[Potassium channel toxin\|Potassium channel toxin]]

	==Reference==		==Reference==

OCA: Protected "2pta" [edit=sysop:move=sysop]

2012-08-14T16:24:32Z

Protected "2pta" [edit=sysop:move=sysop]

← Older revision	Revision as of 16:24, 14 August 2012
(No difference)

OCA at 16:24, 14 August 2012

2012-08-14T16:24:30Z

← Older revision		Revision as of 16:24, 14 August 2012
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	[[Image:2pta.png\|left\|200px]]		[[Image:2pta.png\|left\|200px]]

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	{{STRUCTURE_2pta\| PDB=2pta \| SCENE= }}		{{STRUCTURE_2pta\| PDB=2pta \| SCENE= }}

	===PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES===		===PANDINUS TOXIN K-A (PITX-KA) FROM PANDINUS IMPERATOR, NMR, 20 STRUCTURES===


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	{{ABSTRACT_PUBMED_9062103}}		{{ABSTRACT_PUBMED_9062103}}

	==About this Structure==		==About this Structure==
	~~2PTA is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA].		[[2pta]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pandinus_imperator Pandinus imperator]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PTA OCA].

	==Reference==		==Reference==
	Solution structure for Pandinus toxin K-alpha (PiTX-K alpha), a selective blocker of A-type potassium channels., Tenenholz TC, Rogowski RS, Collins JH, Blaustein MP, Weber DJ, Biochemistry. 1997 Mar 11;36(10):~~2763-71.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~9062103 9062103]~~		<ref group="xtra">PMID:009062103</ref><ref group="xtra">PMID:010631983</ref><references group="xtra"/>
	[[Category: Pandinus imperator]]		[[Category: Pandinus imperator]]
	~~[[Category: Single protein]]~~
	[[Category: Blaustein, M P.]]		[[Category: Blaustein, M P.]]
	[[Category: Collins, J H.]]		[[Category: Collins, J H.]]
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	[[Category: Potassium channel blocker]]		[[Category: Potassium channel blocker]]
	[[Category: Scorpion toxin]]		[[Category: Scorpion toxin]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:14:31 2008''~~