2pvb - Revision history

OCA at 01:19, 21 November 2024

2024-11-21T01:19:42Z

← Older revision		Revision as of 01:19, 21 November 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pvb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pvb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 11:09, 30 August 2023

2023-08-30T11:09:39Z

← Older revision		Revision as of 11:09, 30 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVB FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~, ~~<scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 0.91Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [https://pdbe.org/2pvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [https://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [https://pdbe.org/2pvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [https://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.		[https://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Esox lucius]]		[[Category: Esox lucius]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Declercq~~, J P~~]]		[[Category: Declercq JP]]
	[[Category: Evrard, C]]		[[Category: Evrard C]]
	~~[[Category: Calcium binding protein]]~~
	~~[[Category: Metal binding protein~~]]

OCA at 07:47, 9 March 2022

2022-03-09T07:47:25Z

← Older revision		Revision as of 07:47, 9 March 2022
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	<StructureSection load='2pvb' size='340' side='right'caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>		<StructureSection load='2pvb' size='340' side='right'caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2PVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PVB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [~~http~~://pdbe.org/2pvb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [https://pdbe.org/2pvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [https://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.		[[https://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:57, 3 June 2020

2020-06-03T06:57:54Z

← Older revision		Revision as of 06:57, 3 June 2020
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	==PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).==		==PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).==
	<StructureSection load='2pvb' size='340' side='right' caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>		<StructureSection load='2pvb' size='340' side='right'caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2PVB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://pdbe.org/2pvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://pdbe.org/2pvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
			[[Category: Large Structures]]
	[[Category: Declercq, J P]]		[[Category: Declercq, J P]]
	[[Category: Evrard, C]]		[[Category: Evrard, C]]
	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 08:38, 29 August 2018

2018-08-29T08:38:39Z

← Older revision		Revision as of 08:38, 29 August 2018
Line 1:		Line 1:

	==PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).==		==PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).==
	<StructureSection load='2pvb' size='340' side='right' caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>		<StructureSection load='2pvb' size='340' side='right' caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://pdbe.org/2pvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://pdbe.org/2pvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pvb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pvb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pvb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:12, 9 February 2016

2016-02-09T01:12:20Z

← Older revision		Revision as of 01:12, 9 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pvb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:09, 10 September 2015

2015-09-10T17:09:51Z

← Older revision		Revision as of 17:09, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://pdbe.org/2pvb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2pvb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 03:25, 25 December 2014

2014-12-25T03:25:04Z

← Older revision		Revision as of 03:25, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PRVB_ESOLU PRVB_ESOLU]] In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
	[[Category: Declercq, J P.]]		[[Category: Declercq, J P]]
	[[Category: Evrard, C.]]		[[Category: Evrard, C]]
	[[Category: Calcium binding protein]]		[[Category: Calcium binding protein]]
	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]

OCA at 07:48, 29 September 2014

2014-09-29T07:48:37Z

← Older revision		Revision as of 07:48, 29 September 2014
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	[[Image:~~2pvb~~.~~png~~\|~~left~~\|~~200px~~]]		==PIKE PARVALBUMIN (PI 4.10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0.91 A).==
			<StructureSection load='2pvb' size='340' side='right' caption='[[2pvb]], [[Resolution\|resolution]] 0.91Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PVB FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene><br>
			<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pvb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pvb RCSB], [http://www.ebi.ac.uk/pdbsum/2pvb PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/2pvb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Several crystal structures of parvalbumin (Parv), a typical EF-hand protein, have been reported so far for different species with the best resolution achieving 1.5 A. Using a crystal grown under microgravity conditions, cryotechniques (100 K), and synchrotron radiation, it has now been possible to determine the crystal structure of the fully Ca2+-loaded form of pike (component pI 4.10) Parv.Ca2 at atomic resolution (0.91 A). The availability of such a high quality structure offers the opportunity to contribute to the definition of the validation tools useful for the refinement of protein crystal structures determined to lower resolution. Besides a better definition of most of the elements in the protein three-dimensional structure than in previous studies, the high accuracy thus achieved allows the detection of well-defined alternate conformations, which are observed for 16 residues out of 107 in total. Among them, six occupy an internal position within the hydrophobic core and converge toward two small buried cavities with a total volume of about 60 A3. There is no indication of any water molecule present in these cavities. It is probable that at temperatures of physiological conditions there is a dynamic interconversion between these alternate conformations in an energy-barrier dependent manner. Such motions for which the amplitudes are provided by the present study will be associated with a time-dependent remodeling of the void internal space as part of a slow dynamics regime (millisecond timescales) of the parvalbumin molecule. The relevance of such internal dynamics to function is discussed.

	~~{{STRUCTURE_2pvb\| PDB=2pvb \| SCENE= }}~~		Crystal structure of the EF-hand parvalbumin at atomic resolution (0.91 A) and at low temperature (100 K). Evidence for conformational multistates within the hydrophobic core.,Declercq JP, Evrard C, Lamzin V, Parello J Protein Sci. 1999 Oct;8(10):2194-204. PMID:10548066<ref>PMID:10548066</ref>

	~~===PIKE PARVALBUMIN (PI 4~~.~~10) AT LOW TEMPERATURE (100K) AND ATOMIC RESOLUTION (0~~.~~91 A)~~.~~===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_10548066}}~~

	~~==About this Structure==~~
	~~[[2pvb]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA].~~

	==See Also==		==See Also==
	*[[Parvalbumin\|Parvalbumin]]		*[[Parvalbumin\|Parvalbumin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:010548066<~~/~~ref~~><~~ref group="xtra">PMID:018754631</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Esox lucius]]		[[Category: Esox lucius]]
	[[Category: Declercq, J P.]]		[[Category: Declercq, J P.]]

OCA at 12:07, 20 October 2012

2012-10-20T12:07:30Z

← Older revision		Revision as of 12:07, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2pvb]] is a 1 chain structure ~~of [[Parvalbumin]]~~ with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA].		[[2pvb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Esox_lucius Esox lucius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PVB OCA].

	==See Also==		==See Also==