2py2 - Revision history

OCA at 01:20, 21 November 2024

2024-11-21T01:20:04Z

← Older revision		Revision as of 01:20, 21 November 2024
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	<StructureSection load='2py2' size='340' side='right'caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2py2' size='340' side='right'caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atlantic_herring Atlantic herring~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~hAFP ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [https://pdbe.org/2py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [https://www.ebi.ac.uk/pdbsum/2py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2py2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [https://pdbe.org/2py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [https://www.ebi.ac.uk/pdbsum/2py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2py2 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q91992_CLUHA Q91992_CLUHA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2py2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2py2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Atlantic herring~~]]		[[Category: Clupea harengus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Hew, C L]]		[[Category: Hew C-L]]
	[[Category: Li, Z]]		[[Category: Li Z]]
	[[Category: Lin, Q]]		[[Category: Lin Q]]
	[[Category: Liu, Y]]		[[Category: Liu Y]]
	[[Category: Seetharaman, J]]		[[Category: Seetharaman J]]
	[[Category: Sivaraman, J]]		[[Category: Sivaraman J]]
	~~[[Category: Antifreeze protein]]~~
	~~[[Category: Type ii antifreeze protein~~]]

OCA at 15:35, 17 June 2021

2021-06-17T15:35:59Z

← Older revision		Revision as of 15:35, 17 June 2021
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	==Structure of Herring Type II Antifreeze Protein==		==Structure of Herring Type II Antifreeze Protein==
	<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2py2' size='340' side='right'caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atlantic_herring Atlantic herring]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atlantic_herring Atlantic herring]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [~~http~~://pdbe.org/2py2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2py2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2py2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [https://pdbe.org/2py2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [https://www.ebi.ac.uk/pdbsum/2py2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2py2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[Antifreeze protein\|Antifreeze protein]]		*[[Antifreeze protein 3D structures\|Antifreeze protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Atlantic herring]]		[[Category: Atlantic herring]]
			[[Category: Large Structures]]
	[[Category: Hew, C L]]		[[Category: Hew, C L]]
	[[Category: Li, Z]]		[[Category: Li, Z]]

OCA at 08:34, 29 August 2018

2018-08-29T08:34:41Z

← Older revision		Revision as of 08:34, 29 August 2018
Line 1:		Line 1:

	==Structure of Herring Type II Antifreeze Protein==		==Structure of Herring Type II Antifreeze Protein==
	<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://pdbe.org/2py2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://pdbe.org/2py2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2py2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2py2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2py2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:22, 8 February 2016

2016-02-08T11:22:51Z

← Older revision		Revision as of 11:22, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2py2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:03, 10 September 2015

2015-09-10T11:03:52Z

← Older revision		Revision as of 11:03, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clupea_harengus Clupea harengus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atlantic_herring Atlantic herring]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 ~~Clupea harengus~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Atlantic herring])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://pdbe.org/2py2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2py2" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Clupea harengus~~]]		[[Category: Atlantic herring]]
	[[Category: Hew, C L]]		[[Category: Hew, C L]]
	[[Category: Li, Z]]		[[Category: Li, Z]]

OCA at 15:29, 19 January 2015

2015-01-19T15:29:13Z

← Older revision		Revision as of 15:29, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Clupea harengus])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Clupea harengus])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Clupea harengus]]		[[Category: Clupea harengus]]
	[[Category: Hew, C L.]]		[[Category: Hew, C L]]
	[[Category: Li, Z.]]		[[Category: Li, Z]]
	[[Category: Lin, Q.]]		[[Category: Lin, Q]]
	[[Category: Liu, Y.]]		[[Category: Liu, Y]]
	[[Category: Seetharaman, J.]]		[[Category: Seetharaman, J]]
	[[Category: Sivaraman, J.]]		[[Category: Sivaraman, J]]
	[[Category: Antifreeze protein]]		[[Category: Antifreeze protein]]
	[[Category: Type ii antifreeze protein]]		[[Category: Type ii antifreeze protein]]

OCA at 07:45, 29 September 2014

2014-09-29T07:45:14Z

← Older revision		Revision as of 07:45, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2py2~~.~~png~~\|~~left~~\|~~200px~~]]		==Structure of Herring Type II Antifreeze Protein==
			<StructureSection load='2py2' size='340' side='right' caption='[[2py2]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PY2 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hAFP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7950 Clupea harengus])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2py2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2py2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2py2 RCSB], [http://www.ebi.ac.uk/pdbsum/2py2 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/py/2py2_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			In order to survive under extremely cold environments, many organisms produce antifreeze proteins (AFPs). AFPs inhibit the growth of ice crystals and protect organisms from freezing damage. Fish AFPs can be classified into five distinct types based on their structures. Here we report the structure of herring AFP (hAFP), a Ca(2+)-dependent fish type II AFP. It exhibits a fold similar to the C-type (Ca(2+)-dependent) lectins with unique ice-binding features. The 1.7 A crystal structure of hAFP with bound Ca(2+) and site-directed mutagenesis reveal an ice-binding site consisting of Thr96, Thr98 and Ca(2+)-coordinating residues Asp94 and Glu99, which initiate hAFP adsorption onto the [10-10] prism plane of the ice lattice. The hAFP-ice interaction is further strengthened by the bound Ca(2+) through the coordination with a water molecule of the ice lattice. This Ca(2+)-coordinated ice-binding mechanism is distinct from previously proposed mechanisms for other AFPs. However, phylogenetic analysis suggests that all type II AFPs evolved from the common ancestor and developed different ice-binding modes. We clarify the evolutionary relationship of type II AFPs to sugar-binding lectins.

	~~{{STRUCTURE_2py2\| PDB=2py2 \| SCENE= }}~~		Structure and evolutionary origin of Ca2+-dependent herring type II antifreeze protein.,Liu Y, Li Z, Lin Q, Kosinski J, Seetharaman J, Bujnicki JM, Sivaraman J, Hew CL PLoS ONE. 2007 Jun 20;2(6):e548. PMID:17579720<ref>PMID:17579720</ref>

	~~===Structure~~ of ~~Herring Type II Antifreeze Protein===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_17579720}}~~

	~~==About this Structure==~~
	~~[[2py2]] is a 6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Clupea_harengus Clupea harengus]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=2PY2 OCA].~~

	==See Also==		==See Also==
	*[[Antifreeze protein\|Antifreeze protein]]		*[[Antifreeze protein\|Antifreeze protein]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:017579720<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Clupea harengus]]		[[Category: Clupea harengus]]
	[[Category: Hew, C L.]]		[[Category: Hew, C L.]]

OCA at 09:58, 20 October 2012

2012-10-20T09:58:52Z

← Older revision		Revision as of 09:58, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2py2]] is a 6 chain structure ~~of [[Antifreeze protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA].		[[2py2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA].

	==See Also==		==See Also==

OCA: Protected "2py2" [edit=sysop:move=sysop]

2012-07-26T00:35:59Z

Protected "2py2" [edit=sysop:move=sysop]

← Older revision	Revision as of 00:35, 26 July 2012
(No difference)

OCA at 00:35, 26 July 2012

2012-07-26T00:35:58Z

← Older revision		Revision as of 00:35, 26 July 2012
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	~~{{Seed}}~~
	[[Image:2py2.png\|left\|200px]]		[[Image:2py2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2py2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2py2\| PDB=2py2 \| SCENE= }}		{{STRUCTURE_2py2\| PDB=2py2 \| SCENE= }}

	===Structure of Herring Type II Antifreeze Protein===		===Structure of Herring Type II Antifreeze Protein===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_17579720}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 17579720 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_17579720}}		{{ABSTRACT_PUBMED_17579720}}

	==About this Structure==		==About this Structure==
	~~2PY2~~ is a 6 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA].		[[2py2]] is a 6 chain structure of [[Antifreeze protein]] with sequence from [http://en.wikipedia.org/wiki/Clupea_harengus Clupea harengus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PY2 OCA].

			==See Also==
			*[[Antifreeze protein\|Antifreeze protein]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~17579720~~</ref><references group="xtra"/>		<ref group="xtra">PMID:017579720</ref><references group="xtra"/>
	[[Category: Clupea harengus]]		[[Category: Clupea harengus]]
	[[Category: Hew, C L.]]		[[Category: Hew, C L.]]
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	[[Category: Seetharaman, J.]]		[[Category: Seetharaman, J.]]
	[[Category: Sivaraman, J.]]		[[Category: Sivaraman, J.]]
			[[Category: Antifreeze protein]]
	[[Category: Type ii antifreeze protein]]		[[Category: Type ii antifreeze protein]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:37:38 2009''~~