2rin - Revision history

OCA at 09:29, 6 November 2024

2024-11-06T09:29:59Z

← Older revision		Revision as of 09:29, 6 November 2024
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	<StructureSection load='2rin' size='340' side='right'caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2rin' size='340' side='right'caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Rhizobium_meliloti Rhizobium~~ meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RIN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RIN FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</div~~><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>
	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">opuC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Rhizobium meliloti])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [https://pdbe.org/2rin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [https://www.ebi.ac.uk/pdbsum/2rin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rin ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [https://pdbe.org/2rin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [https://www.ebi.ac.uk/pdbsum/2rin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rin ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q92N37_RHIME Q92N37_RHIME]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2rin_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2rin_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Rhizobium~~ meliloti]]		[[Category: Sinorhizobium meliloti]]
	[[Category: Bremer, E]]		[[Category: Bremer E]]
	[[Category: Hoeing, M]]		[[Category: Hoeing M]]
	[[Category: ~~Oswald, C~~]]		[[Category: Le Rudulier D]]
	[[Category: ~~Rudulier, D Le~~]]		[[Category: Oswald C]]
	[[Category: Schmitt, L]]		[[Category: Schmitt L]]
	[[Category: Smits~~, S H.J~~]]		[[Category: Smits SHJ]]
	[[Category: Sohn-Boeser, L]]		[[Category: Sohn-Boeser L]]
	~~[[Category: Abc-transporter]]~~
	~~[[Category: Acetylcholine]]~~
	~~[[Category: Aromatic box]]~~
	~~[[Category: Protein binding]]~~
	~~[[Category: Type ii binding protein~~]]

OCA at 04:26, 2 July 2021

2021-07-02T04:26:47Z

← Older revision		Revision as of 04:26, 2 July 2021
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	==ABC-transporter choline binding protein in complex with acetylcholine==		==ABC-transporter choline binding protein in complex with acetylcholine==
	<StructureSection load='2rin' size='340' side='right' caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2rin' size='340' side='right'caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rhizobium_meliloti Rhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2RIN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_meliloti Rhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RIN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Rhizobium meliloti])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Rhizobium meliloti])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [~~http~~://pdbe.org/2rin PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2rin PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2rin ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [https://pdbe.org/2rin PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [https://www.ebi.ac.uk/pdbsum/2rin PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rin ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:

	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Rhizobium meliloti]]		[[Category: Rhizobium meliloti]]
	[[Category: Bremer, E]]		[[Category: Bremer, E]]

OCA at 10:56, 5 September 2018

2018-09-05T10:56:45Z

← Older revision		Revision as of 10:56, 5 September 2018
Line 1:		Line 1:

	==ABC-transporter choline binding protein in complex with acetylcholine==		==ABC-transporter choline binding protein in complex with acetylcholine==
	<StructureSection load='2rin' size='340' side='right' caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='2rin' size='340' side='right' caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sinorhizobium_meliloti Sinorhizobium~~ meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RIN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhizobium_meliloti Rhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RIN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 ~~Sinorhizobium~~ meliloti])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Rhizobium meliloti])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://pdbe.org/2rin PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://pdbe.org/2rin PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2rin ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2rin_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2rin_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Sinorhizobium~~ meliloti]]		[[Category: Rhizobium meliloti]]
	[[Category: Bremer, E]]		[[Category: Bremer, E]]
	[[Category: Hoeing, M]]		[[Category: Hoeing, M]]

OCA at 23:29, 9 February 2016

2016-02-09T23:29:57Z

← Older revision		Revision as of 23:29, 9 February 2016
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://pdbe.org/2rin PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rin ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2rin" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 16:28, 19 January 2015

2015-01-19T16:28:46Z

← Older revision		Revision as of 16:28, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RIN FirstGlance]. <br>		<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RIN FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
	[[Category: Bremer, E.]]		[[Category: Bremer, E]]
	[[Category: Hoeing, M.]]		[[Category: Hoeing, M]]
	[[Category: Oswald, C.]]		[[Category: Oswald, C]]
	[[Category: Rudulier, D Le.]]		[[Category: Rudulier, D Le]]
	[[Category: Schmitt, L.]]		[[Category: Schmitt, L]]
	[[Category: Smits, S H.J.]]		[[Category: Smits, S H.J]]
	[[Category: Sohn-Boeser, L.]]		[[Category: Sohn-Boeser, L]]
	[[Category: Abc-transporter]]		[[Category: Abc-transporter]]
	[[Category: Acetylcholine]]		[[Category: Acetylcholine]]

OCA at 08:33, 29 September 2014

2014-09-29T08:33:50Z

← Older revision		Revision as of 08:33, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2rin~~.~~png~~\|~~left~~\|~~200px~~]]		==ABC-transporter choline binding protein in complex with acetylcholine==
			<StructureSection load='2rin' size='340' side='right' caption='[[2rin]], [[Resolution\|resolution]] 1.80Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RIN FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACH:ACETYLCHOLINE'>ACH</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2reg\|2reg]], [[2rej\|2rej]], [[2rf1\|2rf1]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">opuC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2rin FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rin OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2rin RCSB], [http://www.ebi.ac.uk/pdbsum/2rin PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ri/2rin_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The ATP-binding cassette transporter ChoVWX is one of several choline import systems operating in Sinorhizobium meliloti. Here fluorescence-based ligand binding assays were used to quantitate substrate binding by the periplasmic ligand-binding protein ChoX. These data confirmed that ChoX recognizes choline and acetylcholine with high and medium affinity, respectively. We also report the crystal structures of ChoX in complex with either choline or acetylcholine. These structural investigations revealed an architecture of the ChoX binding pocket and mode of substrate binding similar to that reported previously for several compatible solute-binding proteins. Additionally the ChoX-acetylcholine complex permitted a detailed structural comparison with the carbamylcholine-binding site of the acetylcholine-binding protein from the mollusc Lymnaea stagnalis. In addition to the two liganded structures of ChoX, we were also able to solve the crystal structure of ChoX in a closed, substrate-free conformation that revealed an architecture of the ligand-binding site that is superimposable to the closed, ligand-bound form of ChoX. This structure is only the second of its kind and raises the important question of how ATP-binding cassette transporters are capable of distinguishing liganded and unliganded-closed states of the binding protein.

	~~{{STRUCTURE_2rin\| PDB=2rin \| SCENE= }}~~		Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.,Oswald C, Smits SH, Hoing M, Sohn-Bosser L, Dupont L, Le Rudulier D, Schmitt L, Bremer E J Biol Chem. 2008 Nov 21;283(47):32848-59. Epub 2008 Sep 8. PMID:18779321<ref>PMID:18779321</ref>

	~~===ABC-transporter choline binding protein in complex with acetylcholine===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18779321}}~~

	~~==About this Structure==~~
	~~[[2rin]] is~~ a ~~2 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=2RIN OCA].~~

	==See Also==		==See Also==
	*[[ABC transporter\|ABC transporter]]		*[[ABC transporter\|ABC transporter]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018779321<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
	[[Category: Bremer, E.]]		[[Category: Bremer, E.]]

OCA at 15:31, 20 October 2012

2012-10-20T15:31:31Z

← Older revision		Revision as of 15:31, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2rin]] is a 2 chain structure ~~of [[ABC transporter]]~~ with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA].		[[2rin]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA].

	==See Also==		==See Also==

OCA at 18:39, 26 July 2012

2012-07-26T18:39:02Z

← Older revision		Revision as of 18:39, 26 July 2012
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	[[Image:2rin.png\|left\|200px]]		[[Image:2rin.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2rin", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2rin\| PDB=2rin \| SCENE= }}		{{STRUCTURE_2rin\| PDB=2rin \| SCENE= }}

	===ABC-transporter choline binding protein in complex with acetylcholine===		===ABC-transporter choline binding protein in complex with acetylcholine===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18779321}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18779321 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18779321}}		{{ABSTRACT_PUBMED_18779321}}

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	==See Also==		==See Also==
	*[[ABC transporter]]		*[[ABC transporter\|ABC transporter]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18779321~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018779321</ref><references group="xtra"/>
	[[Category: Sinorhizobium meliloti]]		[[Category: Sinorhizobium meliloti]]
	[[Category: Bremer, E.]]		[[Category: Bremer, E.]]

OCA: Protected "2rin" [edit=sysop:move=sysop]

2010-12-27T02:26:30Z

Protected "2rin" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:26, 27 December 2010
(No difference)

OCA at 02:26, 27 December 2010

2010-12-27T02:26:29Z

← Older revision		Revision as of 02:26, 27 December 2010
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2rin.png\|left\|200px]]		[[Image:2rin.png\|left\|200px]]

Line 20:		Line 19:

	==About this Structure==		==About this Structure==
	~~2RIN~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA].		[[2rin]] is a 2 chain structure of [[ABC transporter]] with sequence from [http://en.wikipedia.org/wiki/Sinorhizobium_meliloti Sinorhizobium meliloti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RIN OCA].

			==See Also==
			*[[ABC transporter]]

	==Reference==		==Reference==
Line 37:		Line 39:
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Type ii binding protein]]		[[Category: Type ii binding protein]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:36:32 2009''~~