2ro4 - Revision history

OCA at 07:05, 1 May 2024

2024-05-01T07:05:37Z

← Older revision		Revision as of 07:05, 1 May 2024
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	==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==		==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==
	<StructureSection load='2ro4' size='340' side='right'caption='[[2ro4~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>		<StructureSection load='2ro4' size='340' side='right'caption='[[2ro4]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [https://pdbe.org/2ro4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [https://pdbe.org/2ro4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU]] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>		[https://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ro4 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ro4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	Understanding the DNA recognition and binding by the AbrB-like family of transcriptional regulators is of significant interest since these proteins enable bacteria to elicit the appropriate response to diverse environmental stimuli. Although these "transition-state regulator" proteins have been well characterized at the genetic level, the general and specific mechanisms of DNA binding remain elusive. We present RDC-refined NMR solution structures and dynamic properties of the DNA-binding domains of three Bacillus subtilis transition-state regulators: AbrB, Abh, and SpoVT. We combined previously investigated DNase I footprinting, DNA methylation, gel-shift assays, and mutagenic and NMR studies to generate a structural model of the complex between AbrBN(55) and its cognate promoter, abrB8. These investigations have enabled us to generate a model for the specific nature of the transition-state regulator-DNA interaction, a structure that has remained elusive thus far.

	Insights into the nature of DNA binding of AbrB-like transcription factors.,Sullivan DM, Bobay BG, Kojetin DJ, Thompson RJ, Rance M, Strauch MA, Cavanagh J Structure. 2008 Nov 12;16(11):1702-13. PMID:19000822<ref>PMID:19000822</ref>

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 2ro4" style="background-color:#fffaf0;"></div>~~
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835~~]]		[[Category: Bacillus subtilis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bobay~~, B G~~]]		[[Category: Bobay BG]]
	[[Category: Cavanagh, J]]		[[Category: Cavanagh J]]
	[[Category: Kojetin~~, D J~~]]		[[Category: Kojetin DJ]]
	[[Category: Rance, M]]		[[Category: Rance M]]
	[[Category: Strauch~~, M A~~]]		[[Category: Strauch MA]]
	[[Category: Sullivan~~, D M~~]]		[[Category: Sullivan DM]]
	[[Category: Thompson~~, R J]]~~		[[Category: Thompson RJ]]
	~~[[Category: Activator]]~~
	~~[[Category: Dna-binding]]~~
	~~[[Category: Repressor]]~~
	~~[[Category: Sporulation]]~~
	~~[[Category: Transcription]]~~
	~~[[Category: Transcription regulation~~]]

OCA at 10:34, 7 July 2021

2021-07-07T10:34:17Z

← Older revision		Revision as of 10:34, 7 July 2021
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	==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==		==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==
	<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2ro4' size='340' side='right'caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [~~http~~://pdbe.org/2ro4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [https://pdbe.org/2ro4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU]] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>		[[https://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU]] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
			[[Category: Large Structures]]
	[[Category: Bobay, B G]]		[[Category: Bobay, B G]]
	[[Category: Cavanagh, J]]		[[Category: Cavanagh, J]]

OCA at 11:04, 5 September 2018

2018-09-05T11:04:01Z

← Older revision		Revision as of 11:04, 5 September 2018
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	==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==		==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==
	<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "~~Bacillus globigii~~" ~~Migula 1900~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://pdbe.org/2ro4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://pdbe.org/2ro4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ro4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/2ro4_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/2ro4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus globigii migula 1900~~]]		[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Bobay, B G]]		[[Category: Bobay, B G]]
	[[Category: Cavanagh, J]]		[[Category: Cavanagh, J]]

OCA at 23:41, 9 February 2016

2016-02-09T23:41:50Z

← Older revision		Revision as of 23:41, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus ~~subtilis~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Bacillus globigii" Migula 1900])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://pdbe.org/2ro4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ro4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2ro4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus ~~subtilis~~]]		[[Category: Bacillus globigii migula 1900]]
	[[Category: Bobay, B G]]		[[Category: Bobay, B G]]
	[[Category: Cavanagh, J]]		[[Category: Cavanagh, J]]

OCA at 10:19, 25 December 2014

2014-12-25T10:19:30Z

← Older revision		Revision as of 10:19, 25 December 2014
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	<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='2ro4' size='340' side='right' caption='[[2ro4]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. <br>		<table><tr><td colspan='2'>[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2RO4 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1z0r\|1z0r]], [[2fy9\|2fy9]], [[2ro3\|2ro3]], [[2ro5\|2ro5]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">abrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])</td></tr>
	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum]</span></td></tr>
	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ro4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ro4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ro4 PDBsum]</span></td></tr>		</table>
	<table>		== Function ==
			[[http://www.uniprot.org/uniprot/ABRB_BACSU ABRB_BACSU]] Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription.<ref>PMID:2504584</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 25:
	Insights into the nature of DNA binding of AbrB-like transcription factors.,Sullivan DM, Bobay BG, Kojetin DJ, Thompson RJ, Rance M, Strauch MA, Cavanagh J Structure. 2008 Nov 12;16(11):1702-13. PMID:19000822<ref>PMID:19000822</ref>		Insights into the nature of DNA binding of AbrB-like transcription factors.,Sullivan DM, Bobay BG, Kojetin DJ, Thompson RJ, Rance M, Strauch MA, Cavanagh J Structure. 2008 Nov 12;16(11):1702-13. PMID:19000822<ref>PMID:19000822</ref>

	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 31:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Bobay, B G.]]		[[Category: Bobay, B G]]
	[[Category: Cavanagh, J.]]		[[Category: Cavanagh, J]]
	[[Category: Kojetin, D J.]]		[[Category: Kojetin, D J]]
	[[Category: Rance, M.]]		[[Category: Rance, M]]
	[[Category: Strauch, M A.]]		[[Category: Strauch, M A]]
	[[Category: Sullivan, D M.]]		[[Category: Sullivan, D M]]
	[[Category: Thompson, R J.]]		[[Category: Thompson, R J]]
	[[Category: Activator]]		[[Category: Activator]]
	[[Category: Dna-binding]]		[[Category: Dna-binding]]

OCA at 08:41, 7 May 2014

2014-05-07T08:41:48Z

@@ Line 1: / Line 1: @@
-[[Image:2ro4.png|left|200px]]
+==RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB==
-<!--
+Insights into the nature of DNA binding of AbrB-like transcription factors.,Sullivan DM, Bobay BG, Kojetin DJ, Thompson RJ, Rance M, Strauch MA, Cavanagh J Structure. 2008 Nov 12;16(11):1702-13. PMID:19000822<ref>PMID:19000822</ref>
-===RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB===
+From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+</div>
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_19000822}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 19000822 is the PubMed ID number.
+</StructureSection>
 [[Category: Bacillus subtilis]]
 [[Category: Bobay, B G.]]

OCA: Protected "2ro4" [edit=sysop:move=sysop]

2012-01-11T05:38:53Z

Protected "2ro4" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:38, 11 January 2012
(No difference)

OCA at 05:38, 11 January 2012

2012-01-11T05:38:51Z

← Older revision		Revision as of 05:38, 11 January 2012
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	~~{{Seed}}~~
	[[Image:2ro4.png\|left\|200px]]		[[Image:2ro4.png\|left\|200px]]

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	===RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB===		===RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_19000822}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 19000822 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_19000822}}

	==About this Structure==		==About this Structure==
	~~2RO4~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].		[[2ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].

			==Reference==
			<ref group="xtra">PMID:019000822</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Bobay, B B.]]		[[Category: Bobay, B G.]]
	[[Category: Cavanagh, J.]]		[[Category: Cavanagh, J.]]
	[[Category: Kojetin, D J.]]		[[Category: Kojetin, D J.]]
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	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:53:04 2008''~~

OCA at 05:53, 20 November 2008

2008-11-20T05:53:05Z

← Older revision		Revision as of 05:53, 20 November 2008
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
	2RO4 is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].		2RO4 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	~~[[Category: Single protein]]~~
	[[Category: Bobay, B B.]]		[[Category: Bobay, B B.]]
	[[Category: Cavanagh, J.]]		[[Category: Cavanagh, J.]]
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	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Nov 19 20:12:45 2008''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 20 07:53:04 2008''

OCA at 21:35, 19 November 2008

2008-11-19T21:35:04Z

← Older revision		Revision as of 21:35, 19 November 2008
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
	2RO4 is a ~~2 chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].		2RO4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RO4 OCA].
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
			[[Category: Single protein]]
	[[Category: Bobay, B B.]]		[[Category: Bobay, B B.]]
	[[Category: Cavanagh, J.]]		[[Category: Cavanagh, J.]]
Line 30:		Line 31:
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 19 19:07:58 2008''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 19 20:12:45 2008''