2vb2 - Revision history

OCA at 15:13, 13 December 2023

2023-12-13T15:13:16Z

← Older revision		Revision as of 15:13, 13 December 2023
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	<StructureSection load='2vb2' size='340' side='right'caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vb2' size='340' side='right'caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecobd Ecobd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[1zeq\|1zeq]], [[2vb3\|2vb3]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [https://pdbe.org/2vb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [https://pdbe.org/2vb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>		[https://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Ecobd]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Balakrishnan, G]]		[[Category: Balakrishnan G]]
	[[Category: Davis~~, A V~~]]		[[Category: Davis AV]]
	[[Category: Focia, P]]		[[Category: Focia P]]
	[[Category: Halloran~~, T V.O~~]]		[[Category: O'Halloran TV]]
	[[Category: Penner-Hahn~~, J E~~]]		[[Category: Penner-Hahn JE]]
	[[Category: Spiro~~, T G~~]]		[[Category: Spiro TG]]
	[[Category: Staehlin~~, B M~~]]		[[Category: Staehlin BM]]
	[[Category: Stasser~~, J P~~]]		[[Category: Stasser JP]]
	[[Category: Xue, Y]]		[[Category: Xue Y]]
	~~[[Category: Cation pi]]~~
	~~[[Category: Copper tolerance]]~~
	~~[[Category: Copper transport]]~~
	~~[[Category: Metal transport]]~~
	~~[[Category: Metal-binding~~]]

OCA at 12:43, 23 March 2022

2022-03-23T12:43:16Z

← Older revision		Revision as of 12:43, 23 March 2022
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	<StructureSection load='2vb2' size='340' side='right'caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vb2' size='340' side='right'caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zeq\|1zeq]], [[2vb3\|2vb3]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [~~http~~://pdbe.org/2vb2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [https://pdbe.org/2vb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>		[[https://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:25, 17 June 2020

2020-06-17T11:25:39Z

← Older revision		Revision as of 11:25, 17 June 2020
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	==Crystal structure of Cu(I)CusF==		==Crystal structure of Cu(I)CusF==
	<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vb2' size='340' side='right'caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://pdbe.org/2vb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://pdbe.org/2vb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Ecobd]]		[[Category: Ecobd]]
			[[Category: Large Structures]]
	[[Category: Balakrishnan, G]]		[[Category: Balakrishnan, G]]
	[[Category: Davis, A V]]		[[Category: Davis, A V]]

OCA at 08:39, 12 September 2018

2018-09-12T08:39:54Z

← Older revision		Revision as of 08:39, 12 September 2018
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	==~~CRYSTAL STRUCTURE OF CU~~(I)~~CUSF~~==
			==Crystal structure of Cu(I)CusF==
	<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://pdbe.org/2vb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://pdbe.org/2vb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vb2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vb2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vb2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 21:06, 7 February 2016

2016-02-07T21:06:39Z

← Older revision		Revision as of 21:06, 7 February 2016
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	<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://pdbe.org/2vb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vb2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2vb2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia coli~~]]		[[Category: Ecobd]]
	[[Category: Balakrishnan, G]]		[[Category: Balakrishnan, G]]
	[[Category: Davis, A V]]		[[Category: Davis, A V]]

OCA at 18:15, 24 December 2014

2014-12-24T18:15:23Z

← Older revision		Revision as of 18:15, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/CUSF_ECOLI CUSF_ECOLI]] Part of a cation efflux system that mediates resistance to copper and silver. Binds one copper per polypeptide.<ref>PMID:11399769</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Balakrishnan, G.]]		[[Category: Balakrishnan, G]]
	[[Category: Davis, A V.]]		[[Category: Davis, A V]]
	[[Category: Focia, P.]]		[[Category: Focia, P]]
	[[Category: Halloran, T V.O.]]		[[Category: Halloran, T V.O]]
	[[Category: Penner-Hahn, J E.]]		[[Category: Penner-Hahn, J E]]
	[[Category: Spiro, T G.]]		[[Category: Spiro, T G]]
	[[Category: Staehlin, B M.]]		[[Category: Staehlin, B M]]
	[[Category: Stasser, J P.]]		[[Category: Stasser, J P]]
	[[Category: Xue, Y.]]		[[Category: Xue, Y]]
	[[Category: Cation pi]]		[[Category: Cation pi]]
	[[Category: Copper tolerance]]		[[Category: Copper tolerance]]

OCA at 02:06, 1 October 2014

2014-10-01T02:06:31Z

← Older revision		Revision as of 02:06, 1 October 2014
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	[[Image:~~2vb2~~.~~png~~\|~~left~~\|~~200px~~]]		==CRYSTAL STRUCTURE OF CU(I)CUSF==
			<StructureSection load='2vb2' size='340' side='right' caption='[[2vb2]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VB2 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1zeq\|1zeq]], [[2vb3\|2vb3]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vb2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vb2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vb2 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/2vb2_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Methionine-rich motifs have an important role in copper trafficking factors, including the CusF protein. Here we show that CusF uses a new metal recognition site wherein Cu(I) is tetragonally displaced from a Met2His ligand plane toward a conserved tryptophan. Spectroscopic studies demonstrate that both thioether ligation and strong cation-pi interactions with tryptophan stabilize metal binding. This novel active site chemistry affords mechanisms for control of adventitious metal redox and substitution chemistry.

	~~{{STRUCTURE_2vb2\| PDB=2vb2 \| SCENE= }}~~		Cu(I) recognition via cation-pi and methionine interactions in CusF.,Xue Y, Davis AV, Balakrishnan G, Stasser JP, Staehlin BM, Focia P, Spiro TG, Penner-Hahn JE, O'Halloran TV Nat Chem Biol. 2008 Feb;4(2):107-9. Epub 2007 Dec 23. PMID:18157124<ref>PMID:18157124</ref>

	~~===CRYSTAL STRUCTURE OF CU(I)CUSF===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18157124}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2vb2]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:018157124<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Balakrishnan, G.]]		[[Category: Balakrishnan, G.]]

OCA: Protected "2vb2" [edit=sysop:move=sysop]

2013-01-07T18:51:15Z

Protected "2vb2" [edit=sysop:move=sysop]

← Older revision	Revision as of 18:51, 7 January 2013
(No difference)

OCA at 18:51, 7 January 2013

2013-01-07T18:51:11Z

← Older revision		Revision as of 18:51, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2vb2.png\|left\|200px]]		[[Image:2vb2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vb2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2vb2\| PDB=2vb2 \| SCENE= }}		{{STRUCTURE_2vb2\| PDB=2vb2 \| SCENE= }}

	===CRYSTAL STRUCTURE OF CU(I)CUSF===		===CRYSTAL STRUCTURE OF CU(I)CUSF===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18157124}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18157124 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18157124}}		{{ABSTRACT_PUBMED_18157124}}

	==About this Structure==		==About this Structure==
	~~2VB2~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA].		[[2vb2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18157124~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018157124</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Balakrishnan, G.]]		[[Category: Balakrishnan, G.]]
Line 35:		Line 23:
	[[Category: Xue, Y.]]		[[Category: Xue, Y.]]
	[[Category: Cation pi]]		[[Category: Cation pi]]
	~~[[Category: Copper]]~~
	[[Category: Copper tolerance]]		[[Category: Copper tolerance]]
	[[Category: Copper transport]]		[[Category: Copper transport]]
	[[Category: Metal transport]]		[[Category: Metal transport]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	~~[[Category: Periplasm]]~~

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:30:33 2009''~~

OCA at 14:30, 16 February 2009

2009-02-16T14:30:35Z

← Older revision		Revision as of 14:30, 16 February 2009
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	==About this Structure==		==About this Structure==
	2VB2 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA].		2VB2 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VB2 OCA].

	==Reference==		==Reference==
	Cu(I) recognition via cation-pi and methionine interactions in CusF., Xue Y, Davis AV, Balakrishnan G, Stasser JP, Staehlin BM, Focia P, Spiro TG, Penner-Hahn JE, O'Halloran TV, Nat Chem Biol. 2008 Feb;4(2):107-9. Epub 2007 Dec 23. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18157124 18157124]~~		<ref group="xtra">PMID:18157124</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	~~[[Category: Single protein]]~~
	[[Category: Balakrishnan, G.]]		[[Category: Balakrishnan, G.]]
	[[Category: Davis, A V.]]		[[Category: Davis, A V.]]
Line 43:		Line 42:
	[[Category: Periplasm]]		[[Category: Periplasm]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun Jul 27 19~~:42:~~40 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:30:33 2009''