2vec - Revision history

OCA at 01:26, 21 November 2024

2024-11-21T01:26:34Z

← Older revision		Revision as of 01:26, 21 November 2024
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	<StructureSection load='2vec' size='340' side='right'caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2vec' size='340' side='right'caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VEC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [https://pdbe.org/2vec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [https://www.ebi.ac.uk/pdbsum/2vec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [https://pdbe.org/2vec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [https://www.ebi.ac.uk/pdbsum/2vec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>
	</table>		</table>
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/2vec_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/2vec_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Erlandsen, H]]		[[Category: Erlandsen H]]
	[[Category: Gurmu, D]]		[[Category: Gurmu D]]
	[[Category: Holmgren, A]]		[[Category: Holmgren A]]
	[[Category: Johnson~~, K A~~]]		[[Category: Johnson KA]]
	[[Category: Lu, J]]		[[Category: Lu J]]
	[[Category: Nordlund, P]]		[[Category: Nordlund P]]
	~~[[Category: Bicupin]]~~
	~~[[Category: Cytosolic protein]]~~
	~~[[Category: Reactive cysteine]]~~
	~~[[Category: Ro]]~~
	~~[[Category: Sulfenic acid~~]]

OCA at 11:35, 30 March 2022

2022-03-30T11:35:14Z

← Older revision		Revision as of 11:35, 30 March 2022
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	<StructureSection load='2vec' size='340' side='right'caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2vec' size='340' side='right'caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VEC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [~~http~~://pdbe.org/2vec PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vec PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [https://pdbe.org/2vec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [https://www.ebi.ac.uk/pdbsum/2vec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:48, 25 June 2020

2020-06-25T07:48:39Z

← Older revision		Revision as of 07:48, 25 June 2020
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	==The crystal structure of the protein YhaK from Escherichia coli==		==The crystal structure of the protein YhaK from Escherichia coli==
	<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2vec' size='340' side='right'caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VEC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://pdbe.org/2vec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://pdbe.org/2vec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Erlandsen, H]]		[[Category: Erlandsen, H]]
	[[Category: Gurmu, D]]		[[Category: Gurmu, D]]

OCA at 20:59, 19 September 2018

2018-09-19T20:59:47Z

← Older revision		Revision as of 20:59, 19 September 2018
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	==~~THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI~~==		==The crystal structure of the protein YhaK from Escherichia coli==
	<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/2vec_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/2vec_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:27, 11 August 2016

2016-08-11T15:27:54Z

← Older revision		Revision as of 15:27, 11 August 2016
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	==THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI==		==THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI==
	<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VEC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://pdbe.org/2vec PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vec ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vec ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2vec" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Erlandsen, H]]		[[Category: Erlandsen, H]]
	[[Category: Gurmu, D]]		[[Category: Gurmu, D]]

OCA at 15:37, 19 January 2015

2015-01-19T15:37:10Z

← Older revision		Revision as of 15:37, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VEC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Erlandsen, H.]]		[[Category: Erlandsen, H]]
	[[Category: Gurmu, D.]]		[[Category: Gurmu, D]]
	[[Category: Holmgren, A.]]		[[Category: Holmgren, A]]
	[[Category: Johnson, K A.]]		[[Category: Johnson, K A]]
	[[Category: Lu, J.]]		[[Category: Lu, J]]
	[[Category: Nordlund, P.]]		[[Category: Nordlund, P]]
	[[Category: Bicupin]]		[[Category: Bicupin]]
	[[Category: Cytosolic protein]]		[[Category: Cytosolic protein]]

OCA at 02:04, 1 October 2014

2014-10-01T02:04:06Z

← Older revision		Revision as of 02:04, 1 October 2014
Line 1:		Line 1:
	[[Image:~~2vec~~.~~png~~\|~~left~~\|~~200px~~]]		==THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI==
			<StructureSection load='2vec' size='340' side='right' caption='[[2vec]], [[Resolution\|resolution]] 1.85Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VEC FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene><br>
			<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vec RCSB], [http://www.ebi.ac.uk/pdbsum/2vec PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/2vec_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			YhaK is a protein of unknown function found in low abundance in the cytosol of Escherichia coli. DNA array studies have revealed that YhaK is strongly up-regulated by nitroso-glutathione (GSNO) and also displays a 12-fold increase in expression during biofilm growth of E. coli 83972 and VR50 in human urine. We have determined the YhaK crystal structure and demonstrated that in vitro YhaK is a good marker for monitoring oxidative stresses in E. coli. The YhaK protein structure shows a bicupin fold where the two cupin domains are crosslinked with one intramolecular disulfide bond (Cys10 to Cys204). We found that the third cysteine in YhaK, Cys122, is oxidized to a sulfenic acid. Two chloride ions are found in the structure, one close to the reactive Cys122, and the other on a hydrophobic surface close to a symmetry-related molecule. There are major structural differences at the N-terminus of YhaK compared with similar structures that also display the bicupin fold (YhhW and hPirin). YhaK showed no quercetinase and peroxidase activity. However, reduced YhaK was very sensitive to reactive oxygen species (ROS). The complete, functional E. coli glutaredoxin or thioredoxin systems protected YhaK from oxidation. E. coli thioredoxin reductase and NADPH produced ROS and caused oxidation and oligomerization of reduced YhaK. Taken together, we propose that YhaK is the first of a new sub-class of bicupins that lack the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. Proteins 2008. (c) 2008 Wiley-Liss, Inc.

	~~{{STRUCTURE_2vec\| PDB=2vec \| SCENE= }}~~		The crystal structure of the protein YhaK from Escherichia coli reveals a new subclass of redox sensitive enterobacterial bicupins.,Gurmu D, Lu J, Johnson KA, Nordlund P, Holmgren A, Erlandsen H Proteins. 2008 Jun 16;. PMID:18561187<ref>PMID:18561187</ref>

	~~===THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18561187}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2vec]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:018561187<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Erlandsen, H.]]		[[Category: Erlandsen, H.]]

OCA: Protected "2vec" [edit=sysop:move=sysop]

2013-01-07T18:49:07Z

Protected "2vec" [edit=sysop:move=sysop]

← Older revision	Revision as of 18:49, 7 January 2013
(No difference)

OCA at 18:49, 7 January 2013

2013-01-07T18:49:04Z

← Older revision		Revision as of 18:49, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2vec.png\|left\|200px]]		[[Image:2vec.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vec", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
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	{{STRUCTURE_2vec\| PDB=2vec \| SCENE= }}		{{STRUCTURE_2vec\| PDB=2vec \| SCENE= }}

	===THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI===		===THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18561187}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18561187 is the PubMed ID number.~~
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	{{ABSTRACT_PUBMED_18561187}}		{{ABSTRACT_PUBMED_18561187}}

	==About this Structure==		==About this Structure==
	~~2VEC~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA].		[[2vec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18561187~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018561187</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Erlandsen, H.]]		[[Category: Erlandsen, H.]]
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	[[Category: Ro]]		[[Category: Ro]]
	[[Category: Sulfenic acid]]		[[Category: Sulfenic acid]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:57:29 2009''~~

OCA at 02:57, 18 February 2009

2009-02-18T02:57:31Z

← Older revision		Revision as of 02:57, 18 February 2009
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	==About this Structure==		==About this Structure==
	2VEC is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA].		2VEC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEC OCA].

	==Reference==		==Reference==
	The crystal structure of the protein YhaK from Escherichia coli reveals a new subclass of redox sensitive enterobacterial bicupins., Gurmu D, Lu J, Johnson KA, Nordlund P, Holmgren A, Erlandsen H, Proteins. 2008 Jun 16;. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~18561187 18561187]~~		<ref group="xtra">PMID:18561187</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	~~[[Category: Single protein]]~~
	[[Category: Erlandsen, H.]]		[[Category: Erlandsen, H.]]
	[[Category: Gurmu, D.]]		[[Category: Gurmu, D.]]
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	[[Category: Sulfenic acid]]		[[Category: Sulfenic acid]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 29 11~~:45:~~35 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:57:29 2009''