2vmk - Revision history

OCA at 15:25, 13 December 2023

2023-12-13T15:25:11Z

← Older revision		Revision as of 15:25, 13 December 2023
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	<StructureSection load='2vmk' size='340' side='right'caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='2vmk' size='340' side='right'caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VMK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.3Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [https://pdbe.org/2vmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [https://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [https://pdbe.org/2vmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [https://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.		[https://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Callaghan~~, A J~~]]		[[Category: Callaghan AJ]]
	[[Category: Koslover~~, D J~~]]		[[Category: Koslover DJ]]
	[[Category: Luisi~~, B F~~]]		[[Category: Luisi BF]]
	[[Category: Marcaida~~, M J~~]]		[[Category: Marcaida MJ]]
	[[Category: Martick, M]]		[[Category: Martick M]]
	[[Category: Scott~~, W G]]~~		[[Category: Scott WG]]
	~~[[Category: Cytoplasm]]~~
	~~[[Category: Endonuclease]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Nuclease]]~~
	~~[[Category: Rna processing]]~~
	~~[[Category: Rna turnover]]~~
	~~[[Category: Rna-binding~~]]

OCA at 11:40, 30 March 2022

2022-03-30T11:40:30Z

← Older revision		Revision as of 11:40, 30 March 2022
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	<StructureSection load='2vmk' size='340' side='right'caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='2vmk' size='340' side='right'caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VMK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [~~http~~://pdbe.org/2vmk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [https://pdbe.org/2vmk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [https://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.		[[https://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Ribonuclease 3D structures\|Ribonuclease 3D structures]]		*[[Ribonuclease 3D structures\|Ribonuclease 3D structures]]
	*[[Temp\|Temp]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:09, 25 June 2020

2020-06-25T08:09:38Z

← Older revision		Revision as of 08:09, 25 June 2020
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	==Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain==		==Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain==
	<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='2vmk' size='340' side='right'caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VMK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://pdbe.org/2vmk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://pdbe.org/2vmk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease 3D structures\|Ribonuclease 3D structures]]
	*[[Temp\|Temp]]		*[[Temp\|Temp]]
	== References ==		== References ==
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Callaghan, A J]]		[[Category: Callaghan, A J]]
	[[Category: Koslover, D J]]		[[Category: Koslover, D J]]

OCA at 21:10, 19 September 2018

2018-09-19T21:10:47Z

← Older revision		Revision as of 21:10, 19 September 2018
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	==~~CRYSTAL STRUCTURE OF~~ E. ~~COLI RNASE~~ E ~~APOPROTEIN~~ - ~~CATALYTIC DOMAIN~~==
			==Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain==
	<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://pdbe.org/2vmk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://pdbe.org/2vmk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vmk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/2vmk_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/2vmk_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	[[Category: Martick, M]]		[[Category: Martick, M]]
	[[Category: Scott, W G]]		[[Category: Scott, W G]]
			[[Category: Cytoplasm]]
	[[Category: Endonuclease]]		[[Category: Endonuclease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 19:12, 9 February 2016

2016-02-09T19:12:45Z

← Older revision		Revision as of 19:12, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>		<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VMK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://pdbe.org/2vmk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vmk ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2vmk" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease\|Ribonuclease]]
	*[[Temp\|Temp]]		*[[Temp\|Temp]]
	*[[User:Jaime.Prilusky/Test/tree\|User:Jaime.Prilusky/Test/tree]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Callaghan, A J]]		[[Category: Callaghan, A J]]
	[[Category: Koslover, D J]]		[[Category: Koslover, D J]]

OCA at 08:56, 25 December 2014

2014-12-25T08:56:18Z

← Older revision		Revision as of 08:56, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VMK FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease\|Ribonuclease]]
			*[[Temp\|Temp]]
			*[[User:Jaime.Prilusky/Test/tree\|User:Jaime.Prilusky/Test/tree]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Callaghan, A J.]]		[[Category: Callaghan, A J]]
	[[Category: Koslover, D J.]]		[[Category: Koslover, D J]]
	[[Category: Luisi, B F.]]		[[Category: Luisi, B F]]
	[[Category: Marcaida, M J.]]		[[Category: Marcaida, M J]]
	[[Category: Martick, M.]]		[[Category: Martick, M]]
	[[Category: Scott, W G.]]		[[Category: Scott, W G]]
	[[Category: Endonuclease]]		[[Category: Endonuclease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:13, 29 September 2014

2014-09-29T10:13:55Z

← Older revision		Revision as of 10:13, 29 September 2014
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	[[Image:~~2vmk~~.~~png~~\|~~left~~\|~~200px~~]]		==CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN - CATALYTIC DOMAIN==
			<StructureSection load='2vmk' size='340' side='right' caption='[[2vmk]], [[Resolution\|resolution]] 3.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VMK FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2bx2\|2bx2]], [[2c0b\|2c0b]], [[2c4r\|2c4r]], [[1slj\|1slj]], [[2vrt\|2vrt]], [[1sn8\|1sn8]], [[2fym\|2fym]], [[1smx\|1smx]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vmk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vmk RCSB], [http://www.ebi.ac.uk/pdbsum/2vmk PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/2vmk_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			RNase E is an essential bacterial endoribonuclease involved in the turnover of messenger RNA and the maturation of structured RNA precursors in Escherichia coli. Here, we present the crystal structure of the E. coli RNase E catalytic domain in the apo-state at 3.3 A. This structure indicates that, upon catalytic activation, RNase E undergoes a marked conformational change characterized by the coupled movement of two RNA-binding domains to organize the active site. The structural data suggest a mechanism of RNA recognition and cleavage that explains the enzyme's preference for substrates possessing a 5'-monophosphate and accounts for the protective effect of a triphosphate cap for most transcripts. Internal flexibility within the quaternary structure is also observed, a finding that has implications for recognition of structured RNA substrates and for the mechanism of internal entry for a subset of substrates that are cleaved without 5'-end requirements.

	~~{{STRUCTURE_2vmk\| PDB=2vmk \| SCENE= }}~~		The crystal structure of the Escherichia coli RNase E apoprotein and a mechanism for RNA degradation.,Koslover DJ, Callaghan AJ, Marcaida MJ, Garman EF, Martick M, Scott WG, Luisi BF Structure. 2008 Aug 6;16(8):1238-44. PMID:18682225<ref>PMID:18682225</ref>

	~~===CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN - CATALYTIC DOMAIN===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18682225}}~~

	~~==About this Structure==~~
	~~[[2vmk]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA].~~

	==See Also==		==See Also==
	*[[Ribonuclease\|Ribonuclease]]		*[[Ribonuclease\|Ribonuclease]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018682225<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Callaghan, A J.]]		[[Category: Callaghan, A J.]]

OCA at 14:51, 20 October 2012

2012-10-20T14:51:12Z

← Older revision		Revision as of 14:51, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2vmk]] is a 4 chain structure ~~of [[Ribonuclease]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA].		[[2vmk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA].

	==See Also==		==See Also==

OCA: Protected "2vmk" [edit=sysop:move=sysop]

2012-07-26T16:29:54Z

Protected "2vmk" [edit=sysop:move=sysop]

← Older revision	Revision as of 16:29, 26 July 2012
(No difference)

OCA at 16:29, 26 July 2012

2012-07-26T16:29:53Z

← Older revision		Revision as of 16:29, 26 July 2012
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	~~{{Seed}}~~
	[[Image:2vmk.png\|left\|200px]]		[[Image:2vmk.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vmk", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2vmk\| PDB=2vmk \| SCENE= }}		{{STRUCTURE_2vmk\| PDB=2vmk \| SCENE= }}

	===CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN- CATALYTIC DOMAIN===		===CRYSTAL STRUCTURE OF E. COLI RNASE E APOPROTEIN - CATALYTIC DOMAIN===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18682225}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18682225 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18682225}}		{{ABSTRACT_PUBMED_18682225}}

	==About this Structure==		==About this Structure==
	~~2VMK~~ is a 4 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA].		[[2vmk]] is a 4 chain structure of [[Ribonuclease]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VMK OCA].

			==See Also==
			*[[Ribonuclease\|Ribonuclease]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18682225~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018682225</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Callaghan, A J.]]		[[Category: Callaghan, A J.]]
Line 31:		Line 22:
	[[Category: Martick, M.]]		[[Category: Martick, M.]]
	[[Category: Scott, W G.]]		[[Category: Scott, W G.]]
	~~[[Category: Cytoplasm]]~~
	[[Category: Endonuclease]]		[[Category: Endonuclease]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
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	[[Category: Rna turnover]]		[[Category: Rna turnover]]
	[[Category: Rna-binding]]		[[Category: Rna-binding]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:06:42 2009''~~