2vr2 - Revision history

OCA at 15:29, 13 December 2023

2023-12-13T15:29:09Z

← Older revision		Revision as of 15:29, 13 December 2023
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	<StructureSection load='2vr2' size='340' side='right'caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2vr2' size='340' side='right'caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https:~~/~~/en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase]~~, ~~with EC number [https~~:~~//www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2]~~ </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [https://pdbe.org/2vr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [https://pdbe.org/2vr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>
	</table>		</table>
			== Disease ==
			[https://www.uniprot.org/uniprot/DPYS_HUMAN DPYS_HUMAN] Dihydropyrimidinuria. The disease is caused by variants affecting the gene represented in this entry.
			== Function ==
			[https://www.uniprot.org/uniprot/DPYS_HUMAN DPYS_HUMAN] Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Dihydropyrimidinase]]~~		[[Category: Homo sapiens]]
	~~[[Category: Human~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Andersson, J]]		[[Category: Andersson J]]
	[[Category: Arrowsmith~~, C H]]~~		[[Category: Arrowsmith CH]]
	~~[[Category: Berg, S Van Den~~]]		[[Category: Berglund H]]
	[[Category: Berglund, H]]		[[Category: Busam RD]]
	[[Category: Busam~~, R D~~]]		[[Category: Collins R]]
	[[Category: Collins, R]]		[[Category: Dahlgren LG]]
	[[Category: Dahlgren~~, L G~~]]		[[Category: Edwards AM]]
	[[Category: Edwards~~, A M~~]]		[[Category: Flodin S]]
	[[Category: Flodin, S]]		[[Category: Flores A]]
	[[Category: Flores, A]]		[[Category: Graslund S]]
	[[Category: Graslund, S]]		[[Category: Hammarstrom M]]
	[[Category: Hammarstrom, M]]		[[Category: Herman MD]]
	[[Category: Herman~~, M D~~]]		[[Category: Johansson I]]
	[[Category: Johansson, I]]		[[Category: Kallas A]]
	[[Category: Kallas, A]]		[[Category: Karlberg T]]
	[[Category: Karlberg, T]]		[[Category: Kotenyova T]]
	[[Category: Kotenyova, T]]		[[Category: Lehtio L]]
	[[Category: Lehtio, L]]		[[Category: Moche M]]
	[[Category: Moche, M]]		[[Category: Nilsson ME]]
	[[Category: Nilsson~~, M E~~]]		[[Category: Nordlund P]]
	[[Category: Nordlund, P]]		[[Category: Nyman T]]
	[[Category: Nyman, T]]		[[Category: Persson C]]
	[[Category: Persson, C]]		[[Category: Sagemark J]]
	~~[[Category: Structural genomic~~]]		[[Category: Svensson L]]
	[[Category: Sagemark, J]]		[[Category: Thorsell AG]]
	[[Category: Svensson, L]]		[[Category: Tresaugues L]]
	[[Category: Thorsell~~, A G~~]]		[[Category: Van Den Berg S]]
	[[Category: Tresaugues, L]]		[[Category: Weigelt J]]
	[[Category: ~~Weigelt, J~~]]		[[Category: Welin M]]
	[[Category: ~~Welin, M~~]]		[[Category: Wikstrom M]]
	[[Category: ~~Wikstrom,~~ M]]
	[[Category: ~~Dhp]]~~
	~~[[Category: Dhpase]]~~
	~~[[Category: Dihydropyrimidine amidohydrolase]]~~
	~~[[Category: Disease mutation]]~~
	~~[[Category: Dpy]]~~
	~~[[Category: Hydantoinase]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Metal-binding]]~~
	~~[[Category: Nucleotide metabolism]]~~
	~~[[Category: Zn-binding~~]]

OCA at 11:44, 30 March 2022

2022-03-30T11:44:20Z

← Older revision		Revision as of 11:44, 30 March 2022
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	<StructureSection load='2vr2' size='340' side='right'caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2vr2' size='340' side='right'caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [~~http~~://pdbe.org/2vr2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [https://pdbe.org/2vr2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [https://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:24, 25 June 2020

2020-06-25T08:24:06Z

← Older revision		Revision as of 08:24, 25 June 2020
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	==Human Dihydropyrimidinase==		==Human Dihydropyrimidinase==
	<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2vr2' size='340' side='right'caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://pdbe.org/2vr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://pdbe.org/2vr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	[[Category: Dihydropyrimidinase]]		[[Category: Dihydropyrimidinase]]
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Andersson, J]]		[[Category: Andersson, J]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]

OCA at 21:18, 19 September 2018

2018-09-19T21:18:32Z

← Older revision		Revision as of 21:18, 19 September 2018
Line 1:		Line 1:

	==Human Dihydropyrimidinase==		==Human Dihydropyrimidinase==
	<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://pdbe.org/2vr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://pdbe.org/2vr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vr2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vr2_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vr2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:25, 8 February 2016

2016-02-08T17:25:54Z

← Older revision		Revision as of 17:25, 8 February 2016
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://pdbe.org/2vr2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vr2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 07:17, 6 May 2015

2015-05-06T07:17:41Z

← Older revision		Revision as of 07:17, 6 May 2015
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	==~~HUMAN DIHYDROPYRIMIDINASE~~==		==Human Dihydropyrimidinase==
	<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Dihydropyrimidinase]]		[[Category: Dihydropyrimidinase]]
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Andersson, J]]		[[Category: Andersson, J]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
Line 27:		Line 27:
	[[Category: Busam, R D]]		[[Category: Busam, R D]]
	[[Category: Collins, R]]		[[Category: Collins, R]]
	~~[[Category: Structural genomic]]~~
	[[Category: Dahlgren, L G]]		[[Category: Dahlgren, L G]]
	[[Category: Edwards, A M]]		[[Category: Edwards, A M]]
Line 45:		Line 44:
	[[Category: Nyman, T]]		[[Category: Nyman, T]]
	[[Category: Persson, C]]		[[Category: Persson, C]]
			[[Category: Structural genomic]]
	[[Category: Sagemark, J]]		[[Category: Sagemark, J]]
	[[Category: Svensson, L]]		[[Category: Svensson, L]]

OCA at 14:18, 19 January 2015

2015-01-19T14:18:48Z

← Older revision		Revision as of 14:18, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 21:
	[[Category: Dihydropyrimidinase]]		[[Category: Dihydropyrimidinase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Andersson, J.]]		[[Category: Andersson, J]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H]]
	[[Category: Berg, S Van Den.]]		[[Category: Berg, S Van Den]]
	[[Category: Berglund, H.]]		[[Category: Berglund, H]]
	[[Category: Busam, R D.]]		[[Category: Busam, R D]]
	[[Category: Collins, R.]]		[[Category: Collins, R]]
	[[Category: ~~Consortium,~~ Structural ~~Genomics.~~]]		[[Category: Structural genomic]]
	[[Category: Dahlgren, L G.]]		[[Category: Dahlgren, L G]]
	[[Category: Edwards, A M.]]		[[Category: Edwards, A M]]
	[[Category: Flodin, S.]]		[[Category: Flodin, S]]
	[[Category: Flores, A.]]		[[Category: Flores, A]]
	[[Category: Graslund, S.]]		[[Category: Graslund, S]]
	[[Category: Hammarstrom, M.]]		[[Category: Hammarstrom, M]]
	[[Category: Herman, M D.]]		[[Category: Herman, M D]]
	[[Category: Johansson, I.]]		[[Category: Johansson, I]]
	[[Category: Kallas, A.]]		[[Category: Kallas, A]]
	[[Category: Karlberg, T.]]		[[Category: Karlberg, T]]
	[[Category: Kotenyova, T.]]		[[Category: Kotenyova, T]]
	[[Category: Lehtio, L.]]		[[Category: Lehtio, L]]
	[[Category: Moche, M.]]		[[Category: Moche, M]]
	[[Category: Nilsson, M E.]]		[[Category: Nilsson, M E]]
	[[Category: Nordlund, P.]]		[[Category: Nordlund, P]]
	[[Category: Nyman, T.]]		[[Category: Nyman, T]]
	[[Category: Persson, C.]]		[[Category: Persson, C]]
	[[Category: Sagemark, J.]]		[[Category: Sagemark, J]]
	[[Category: Svensson, L.]]		[[Category: Svensson, L]]
	[[Category: Thorsell, A G.]]		[[Category: Thorsell, A G]]
	[[Category: Tresaugues, L.]]		[[Category: Tresaugues, L]]
	[[Category: Weigelt, J.]]		[[Category: Weigelt, J]]
	[[Category: Welin, M.]]		[[Category: Welin, M]]
	[[Category: Wikstrom, M.]]		[[Category: Wikstrom, M]]
	[[Category: Dhp]]		[[Category: Dhp]]
	[[Category: Dhpase]]		[[Category: Dhpase]]
	~~[[Category: Dihydropyrimidinase]]~~
	[[Category: Dihydropyrimidine amidohydrolase]]		[[Category: Dihydropyrimidine amidohydrolase]]
	[[Category: Disease mutation]]		[[Category: Disease mutation]]

OCA at 01:40, 1 October 2014

2014-10-01T01:40:42Z

← Older revision		Revision as of 01:40, 1 October 2014
Line 1:		Line 1:
	[[~~Image:~~2vr2~~.png\|left~~\|~~200px~~]]		==HUMAN DIHYDROPYRIMIDINASE==
			<StructureSection load='2vr2' size='340' side='right' caption='[[2vr2]], [[Resolution\|resolution]] 2.80Å' scene=''>
	~~{{STRUCTURE_2vr2\| PDB~~=~~2vr2 \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VR2 FirstGlance]. <br>
	==~~=HUMAN DIHYDROPYRIMIDINASE=~~==		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vr2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vr2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vr2 RCSB], [http://www.ebi.ac.uk/pdbsum/2vr2 PDBsum]</span></td></tr>
	~~==About this Structure=~~=		<table>
	[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA].		== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/2vr2_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Dihydropyrimidinase]]		[[Category: Dihydropyrimidinase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]

OCA: Protected "2vr2" [edit=sysop:move=sysop]

2013-01-07T21:04:43Z

Protected "2vr2" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:04, 7 January 2013
(No difference)

OCA at 21:04, 7 January 2013

2013-01-07T21:04:40Z

← Older revision		Revision as of 21:04, 7 January 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2vr2.png\|left\|200px]]		[[Image:2vr2.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vr2", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2vr2\| PDB=2vr2 \| SCENE= }}		{{STRUCTURE_2vr2\| PDB=2vr2 \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
	~~2VR2~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA].		[[2vr2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VR2 OCA].
	[[Category: Dihydropyrimidinase]]		[[Category: Dihydropyrimidinase]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
Line 58:		Line 51:
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	[[Category: Nucleotide metabolism]]		[[Category: Nucleotide metabolism]]
	~~[[Category: Zinc]]~~
	[[Category: Zn-binding]]		[[Category: Zn-binding]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:46:25 2009''~~