2vs3 - Revision history

OCA at 15:30, 13 December 2023

2023-12-13T15:30:15Z

← Older revision		Revision as of 15:30, 13 December 2023
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	<StructureSection load='2vs3' size='340' side='right'caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2vs3' size='340' side='right'caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~"><~~scene name~~='~~pdbligand~~=MN:~~MANGANESE+(II)+ION'~~>MN</~~scene~~>, <scene name='pdbligand=~~UDP~~:~~URIDINE~~-5-~~DIPHOSPHATE~~'>~~UDP~~</scene>, <scene name='pdbligand=~~GAL~~:~~BETA-D-GALACTOSE~~'>~~GAL~~</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene><~~/td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;~~'>[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</div></td><~~/tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PRD_900019:N-acetyl-alpha-lactosamine'>PRD_900019</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [https://pdbe.org/2vs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [https://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [https://pdbe.org/2vs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [https://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN]] Transfer of galactose from UDP-galactose to an acceptor molecule (R).		[https://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN] Transfer of galactose from UDP-galactose to an acceptor molecule (R).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bovin~~]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]~~		[[Category: Acharya KR]]
	[[Category: Acharya~~, K R~~]]		[[Category: Brew K]]
	[[Category: Brew, K]]		[[Category: Jamaluddin H]]
	[[Category: Jamaluddin, H]]		[[Category: Thiyagarajan N]]
	[[Category: Thiyagarajan, N]]		[[Category: Tumbale P]]
	[[Category: Tumbale, P]]
	~~[[Category: Active-site mutant]]~~
	~~[[Category: Alpha-3gt]]~~
	~~[[Category: Alpha3gt]]~~
	~~[[Category: Galactose]]~~
	~~[[Category: Glycoprotein]]~~
	~~[[Category: Glycosyltransferase]]~~
	~~[[Category: Golgi apparatus]]~~
	~~[[Category: Gt]]~~
	~~[[Category: Manganese]]~~
	~~[[Category: Membrane]]~~
	~~[[Category: Metal-binding]]~~
	~~[[Category: N-acetyl lactosamine]]~~
	~~[[Category: Signal-anchor]]~~
	~~[[Category: Transferase]]~~
	~~[[Category: Transmembrane]]~~
	~~[[Category: Udp~~]]

OCA at 11:45, 30 March 2022

2022-03-30T11:45:21Z

← Older revision		Revision as of 11:45, 30 March 2022
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	<StructureSection load='2vs3' size='340' side='right'caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2vs3' size='340' side='right'caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=~~NLC~~:2-~~(ACETYLAMINO)-2-DEOXY-4-O~~-BETA-D-~~GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE~~'>~~NLC~~</scene>, <scene name='pdbligand=~~UDP~~:~~URIDINE~~-5-~~DIPHOSPHATE~~'>~~UDP~~</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</div></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [~~http~~://pdbe.org/2vs3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [https://pdbe.org/2vs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [https://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN]] Transfer of galactose from UDP-galactose to an acceptor molecule (R).		[[https://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN]] Transfer of galactose from UDP-galactose to an acceptor molecule (R).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:27, 25 June 2020

2020-06-25T08:27:11Z

← Older revision		Revision as of 08:27, 25 June 2020
Line 1:		Line 1:

	==THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)==		==THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)==
	<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2vs3' size='340' side='right'caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://pdbe.org/2vs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://pdbe.org/2vs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 32:		Line 32:

	==See Also==		==See Also==
	*[[Glycosyltransferase\|Glycosyltransferase]]		*[[Glycosyltransferase 3D structures\|Glycosyltransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 38:		Line 38:
	</StructureSection>		</StructureSection>
	[[Category: Bovin]]		[[Category: Bovin]]
			[[Category: Large Structures]]
	[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]		[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]
	[[Category: Acharya, K R]]		[[Category: Acharya, K R]]

OCA at 21:14, 19 September 2018

2018-09-19T21:14:42Z

← Older revision		Revision as of 21:14, 19 September 2018
Line 1:		Line 1:
	==THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ~~ALPHA~~-1,3 GALACTOSYLTRANSFERASE (~~ALPHA3GT~~)==
			==THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT)==
	<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://pdbe.org/2vs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://pdbe.org/2vs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vs3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vs3_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vs3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 03:35, 10 February 2016

2016-02-10T03:35:08Z

← Older revision		Revision as of 03:35, 10 February 2016
Line 2:		Line 2:
	<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://pdbe.org/2vs3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vs3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2vs3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bos taurus~~]]		[[Category: Bovin]]
	[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]		[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]
	[[Category: Acharya, K R]]		[[Category: Acharya, K R]]

OCA at 11:30, 25 December 2014

2014-12-25T11:30:59Z

← Older revision		Revision as of 11:30, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/GGTA1_BOVIN GGTA1_BOVIN]] Transfer of galactose from UDP-galactose to an acceptor molecule (R).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]		[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]
	[[Category: Acharya, K R.]]		[[Category: Acharya, K R]]
	[[Category: Brew, K.]]		[[Category: Brew, K]]
	[[Category: Jamaluddin, H.]]		[[Category: Jamaluddin, H]]
	[[Category: Thiyagarajan, N.]]		[[Category: Thiyagarajan, N]]
	[[Category: Tumbale, P.]]		[[Category: Tumbale, P]]
	[[Category: Active-site mutant]]		[[Category: Active-site mutant]]
	[[Category: Alpha-3gt]]		[[Category: Alpha-3gt]]

OCA at 07:02, 29 September 2014

2014-09-29T07:02:39Z

← Older revision		Revision as of 07:02, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2vs3~~.~~png~~\|~~left~~\|~~200px~~]]		==THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ALPHA-1,3 GALACTOSYLTRANSFERASE (ALPHA3GT)==
			<StructureSection load='2vs3' size='340' side='right' caption='[[2vs3]], [[Resolution\|resolution]] 2.20Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VS3 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NLC:2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE'>NLC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1vzt\|1vzt]], [[2jcf\|2jcf]], [[1gx0\|1gx0]], [[1vzx\|1vzx]], [[1o7q\|1o7q]], [[1gx4\|1gx4]], [[2jcj\|2jcj]], [[2jck\|2jck]], [[2vfz\|2vfz]], [[1g93\|1g93]], [[1g8o\|1g8o]], [[1gwv\|1gwv]], [[1k4v\|1k4v]], [[1vzu\|1vzu]], [[1o7o\|1o7o]], [[2jcl\|2jcl]], [[2jco\|2jco]], [[1gww\|1gww]], [[1fg5\|1fg5]], [[2vs4\|2vs4]]</td></tr>
			<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acetyllactosaminide_3-alpha-galactosyltransferase N-acetyllactosaminide 3-alpha-galactosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.87 2.4.1.87] </span></td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vs3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vs3 RCSB], [http://www.ebi.ac.uk/pdbsum/2vs3 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vs/2vs3_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			alpha-1,3-Galactosyltransferase (alpha3GT) catalyzes the transfer of galactose from UDP-galactose to form an alpha 1-3 link with beta-linked galactosides; it is part of a family of homologous retaining glycosyltransferases that includes the histo-blood group A and B glycosyltransferases, Forssman glycolipid synthase, iGb3 synthase, and some uncharacterized prokaryotic glycosyltransferases. In mammals, the presence or absence of active forms of these enzymes results in antigenic differences between individuals and species that modulate the interplay between the immune system and pathogens. The catalytic mechanism of alpha3GT is controversial, but the structure of an enzyme complex with the donor substrate could illuminate both this and the basis of donor substrate specificity. We report here the structure of the complex of a low-activity mutant alpha3GT with UDP-galactose (UDP-gal) exhibiting a bent configuration stabilized by interactions of the galactose with multiple residues in the enzyme including those in a highly conserved region (His315 to Ser318). Analysis of the properties of mutants containing substitutions for these residues shows that catalytic activity is strongly affected by His315 and Asp316. The negative charge of Asp316 is crucial for catalytic activity, and structural studies of two mutants show that its interaction with Arg202 is needed for an active site structure that facilitates the binding of UDP-gal in a catalytically competent conformation.

	~~{{STRUCTURE_2vs3\| PDB=2vs3 \| SCENE= }}~~		Structural Basis of UDP-galactose Binding by alpha-1,3-Galactosyltransferase (alpha3GT): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity.,Tumbale P, Jamaluddin H, Thiyagarajan N, Brew K, Acharya KR Biochemistry. 2008 Jul 24. PMID:18651752<ref>PMID:18651752</ref>

	~~===THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ALPHA-1~~,~~3 GALACTOSYLTRANSFERASE (ALPHA3GT)===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18651752}}~~

	~~==About this Structure==~~
	~~[[2vs3]] is~~ a ~~2 chain structure with sequence from [http://en.wikipedia~~.~~org/wiki/Bos_taurus Bos taurus]~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann.ac.il/oca-bin~~/~~ocashort?id=2VS3 OCA].~~

	==See Also==		==See Also==
	*[[~~Galactosyltransferase~~\|~~Galactosyltransferase~~]]		*[[Glycosyltransferase\|Glycosyltransferase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018651752<~~/~~ref~~><~~ref group="xtra">PMID:017721439</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]		[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]

OCA at 16:11, 20 October 2012

2012-10-20T16:11:36Z

← Older revision		Revision as of 16:11, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[2vs3]] is a 2 chain structure ~~of [[Galactosyltransferase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA].		[[2vs3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA].

	==See Also==		==See Also==

OCA: Protected "2vs3" [edit=sysop:move=sysop]

2012-07-26T20:53:26Z

Protected "2vs3" [edit=sysop:move=sysop]

← Older revision	Revision as of 20:53, 26 July 2012
(No difference)

OCA at 20:53, 26 July 2012

2012-07-26T20:53:24Z

← Older revision		Revision as of 20:53, 26 July 2012
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:2vs3.png\|left\|200px]]		[[Image:2vs3.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vs3", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2vs3\| PDB=2vs3 \| SCENE= }}		{{STRUCTURE_2vs3\| PDB=2vs3 \| SCENE= }}

	===THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ALPHA-1,3 GALACTOSYLTRANSFERASE (ALPHA3GT)===		===THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ALPHA-1,3 GALACTOSYLTRANSFERASE (ALPHA3GT)===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18651752}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18651752 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18651752}}		{{ABSTRACT_PUBMED_18651752}}

	==About this Structure==		==About this Structure==
	~~2VS3~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA].		[[2vs3]] is a 2 chain structure of [[Galactosyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VS3 OCA].

			==See Also==
			*[[Galactosyltransferase\|Galactosyltransferase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18651752~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018651752</ref><ref group="xtra">PMID:017721439</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]		[[Category: N-acetyllactosaminide 3-alpha-galactosyltransferase]]
Line 47:		Line 38:
	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Udp]]		[[Category: Udp]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:06:39 2009''~~