2vx4 - Revision history

OCA at 15:35, 13 December 2023

2023-12-13T15:35:54Z

← Older revision		Revision as of 15:35, 13 December 2023
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	<StructureSection load='2vx4' size='340' side='right'caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vx4' size='340' side='right'caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height~~: ~~3em;~~'>~~[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]~~</~~div~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [https://pdbe.org/2vx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [https://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [https://pdbe.org/2vx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [https://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>
	</table>		</table>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Cellvibrio ~~cellulosa nagy et al. 2002~~]]		[[Category: Cellvibrio japonicus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Cartmell, A]]		[[Category: Cartmell A]]
	[[Category: Davies~~, G J~~]]		[[Category: Davies GJ]]
	[[Category: Ducros~~, V M.~~A]]		[[Category: Ducros VM-A]]
	[[Category: Gilbert~~, H J~~]]		[[Category: Gilbert HJ]]
	[[Category: Suits~~, M D.L~~]]		[[Category: Suits MDL]]
	[[Category: Topakas, E]]		[[Category: Topakas E]]
	~~[[Category: Cellvibrio japonicus]]~~
	~~[[Category: Cjman26c]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Mannanase~~]]

OCA at 11:48, 30 March 2022

2022-03-30T11:48:09Z

← Older revision		Revision as of 11:48, 30 March 2022
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	<StructureSection load='2vx4' size='340' side='right'caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vx4' size='340' side='right'caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [~~http~~://pdbe.org/2vx4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [https://pdbe.org/2vx4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [https://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:38, 25 June 2020

2020-06-25T08:38:28Z

← Older revision		Revision as of 08:38, 25 June 2020
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	==CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM==		==CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM==
	<StructureSection load='2vx4' size='340' side='right' caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vx4' size='340' side='right'caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://pdbe.org/2vx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://pdbe.org/2vx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Cellvibrio cellulosa nagy et al. 2002]]		[[Category: Cellvibrio cellulosa nagy et al. 2002]]
			[[Category: Large Structures]]
	[[Category: Cartmell, A]]		[[Category: Cartmell, A]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]

OCA at 21:26, 19 September 2018

2018-09-19T21:26:24Z

← Older revision		Revision as of 21:26, 19 September 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vx4_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vx4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:05, 11 August 2016

2016-08-11T14:05:13Z

← Older revision		Revision as of 14:05, 11 August 2016
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	==CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM==		==CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM==
	<StructureSection load='2vx4' size='340' side='right' caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='2vx4' size='340' side='right' caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Cellvibrio_japonicus Cellvibrio japonicus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"cellvibrio_cellulosa"_nagy_et_al._2002 "cellvibrio cellulosa" nagy et al. 2002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://pdbe.org/2vx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vx4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vx4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2vx4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Cellvibrio ~~japonicus~~]]		[[Category: Cellvibrio cellulosa nagy et al. 2002]]
	[[Category: Cartmell, A]]		[[Category: Cartmell, A]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
Line 36:		Line 38:
	[[Category: Suits, M D.L]]		[[Category: Suits, M D.L]]
	[[Category: Topakas, E]]		[[Category: Topakas, E]]
			[[Category: Cellvibrio japonicus]]
	[[Category: Cjman26c]]		[[Category: Cjman26c]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Mannanase]]		[[Category: Mannanase]]

OCA at 18:41, 19 January 2015

2015-01-19T18:41:14Z

← Older revision		Revision as of 18:41, 19 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum]</span></td></tr>
	<table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Cellvibrio japonicus]]		[[Category: Cellvibrio japonicus]]
	[[Category: Cartmell, A.]]		[[Category: Cartmell, A]]
	[[Category: Davies, G J.]]		[[Category: Davies, G J]]
	[[Category: Ducros, V M.A.]]		[[Category: Ducros, V M.A]]
	[[Category: Gilbert, H J.]]		[[Category: Gilbert, H J]]
	[[Category: Suits, M D.L.]]		[[Category: Suits, M D.L]]
	[[Category: Topakas, E~~.]]~~		[[Category: Topakas, E]]
	~~[[Category: Cellvibrio japonicus~~]]
	[[Category: Cjman26c]]		[[Category: Cjman26c]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Mannanase]]		[[Category: Mannanase]]

OCA at 02:20, 1 October 2014

2014-10-01T02:20:51Z

← Older revision		Revision as of 02:20, 1 October 2014
Line 1:		Line 1:
	[[Image:~~2vx4~~.~~png~~\|~~left~~\|~~200px~~]]		==CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM==
			<StructureSection load='2vx4' size='340' side='right' caption='[[2vx4]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VX4 FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2vx7\|2vx7]], [[2vx6\|2vx6]], [[2vx5\|2vx5]]</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vx4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vx4 RCSB], [http://www.ebi.ac.uk/pdbsum/2vx4 PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vx4_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The microbial degradation of the plant cell wall is a pivotal biological process that is of increasing industrial significance. One of the major plant structural polysaccharides is mannan, a beta-1,4-linked d-mannose polymer, which is hydrolyzed by endo- and exo-acting mannanases. The mechanisms by which the exo-acting enzymes target the chain ends of mannan and how galactose decorations influence activity are poorly understood. Here we report the crystal structure and biochemical properties of CjMan26C, a Cellvibrio japonicus GH26 mannanase. The exo-acting enzyme releases the disaccharide mannobiose from the nonreducing end of mannan and mannooligosaccharides, harnessing four mannose-binding subsites extending from -2 to +2. The structure of CjMan26C is very similar to that of the endo-acting C. japonicus mannanase CjMan26A. The exo-activity displayed by CjMan26C, however, reflects a subtle change in surface topography in which a four-residue extension of surface loop creates a steric block at the distal glycone -2 subsite. endo-Activity can be introduced into enzyme variants through truncation of an aspartate side chain, a component of a surface loop, or by removing both the aspartate and its flanking residues. The structure of catalytically competent CjMan26C, in complex with a decorated manno-oligosaccharide, reveals a predominantly unhydrolyzed substrate in an approximate (1)S(5) conformation. The complex structure helps to explain how the substrate "side chain" decorations greatly reduce the activity of the enzyme; the galactose side chain at the -1 subsite makes polar interactions with the aglycone mannose, possibly leading to suboptimal binding and impaired leaving group departure. This report reveals how subtle differences in the loops surrounding the active site of a glycoside hydrolase can lead to a change in the mode of action of the enzyme.

	~~{{STRUCTURE_2vx4\| PDB=2vx4 \| SCENE= }}~~		The Cellvibrio japonicus mannanase CjMan26C displays a unique exo-mode of action that is conferred by subtle changes to the distal region of the active site.,Cartmell A, Topakas E, Ducros VM, Suits MD, Davies GJ, Gilbert HJ J Biol Chem. 2008 Dec 5;283(49):34403-13. Epub 2008 Sep 17. PMID:18799462<ref>PMID:18799462</ref>

	~~===CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18799462}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2vx4]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:018799462<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Cellvibrio japonicus]]		[[Category: Cellvibrio japonicus]]
	[[Category: Cartmell, A.]]		[[Category: Cartmell, A.]]

OCA: Protected "2vx4" [edit=sysop:move=sysop]

2013-01-07T23:17:34Z

Protected "2vx4" [edit=sysop:move=sysop]

← Older revision	Revision as of 23:17, 7 January 2013
(No difference)

OCA at 23:17, 7 January 2013

2013-01-07T23:17:31Z

← Older revision		Revision as of 23:17, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2vx4.png\|left\|200px]]		[[Image:2vx4.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2vx4", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2vx4\| PDB=2vx4 \| SCENE= }}		{{STRUCTURE_2vx4\| PDB=2vx4 \| SCENE= }}

	===CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM===		===CELLVIBRIO JAPONICUS MANNANASE CJMAN26C NATIVE FORM===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18799462}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18799462 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18799462}}		{{ABSTRACT_PUBMED_18799462}}

	==About this Structure==		==About this Structure==
	~~2VX4~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA].		[[2vx4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18799462~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018799462</ref><references group="xtra"/>
	[[Category: Cellvibrio japonicus]]		[[Category: Cellvibrio japonicus]]
	[[Category: Cartmell, A.]]		[[Category: Cartmell, A.]]
Line 35:		Line 23:
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Mannanase]]		[[Category: Mannanase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:45:03 2009''~~

OCA at 01:45, 18 February 2009

2009-02-18T01:45:05Z

← Older revision		Revision as of 01:45, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
	2VX4 is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA].		2VX4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VX4 OCA].

	==Reference==		==Reference==
	The Cellvibrio japonicus Mannanase CjMan26C Displays a Unique exo-Mode of Action That Is Conferred by Subtle Changes to the Distal Region of the Active Site., Cartmell A, Topakas E, Ducros VM, Suits MD, Davies GJ, Gilbert HJ, J Biol Chem. 2008 Dec 5;283(49):34403-13. Epub 2008 Sep 17. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18799462 18799462]~~		<ref group="xtra">PMID:18799462</ref><references group="xtra"/>
	[[Category: Cellvibrio japonicus]]		[[Category: Cellvibrio japonicus]]
	[[Category: ~~Single protein~~]]		[[Category: Cartmell, A.]]
	[[Category: ~~Pdbx_ordinal=~~, ~~<PDBx~~:~~audit_author~~.]]		[[Category: Davies, G J.]]
			[[Category: Ducros, V M.A.]]
			[[Category: Gilbert, H J.]]
			[[Category: Suits, M D.L.]]
			[[Category: Topakas, E.]]
	[[Category: Cellvibrio japonicus]]		[[Category: Cellvibrio japonicus]]
	[[Category: Cjman26c]]		[[Category: Cjman26c]]
Line 32:		Line 36:
	[[Category: Mannanase]]		[[Category: Mannanase]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec 10 20~~:18:~~19 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:45:03 2009''