2wbc - Revision history

OCA at 08:40, 30 October 2024

2024-10-30T08:40:07Z

← Older revision		Revision as of 08:40, 30 October 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [https://pdbe.org/2wbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [https://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [https://pdbe.org/2wbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [https://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/ICW3_PSOTE ICW3_PSOTE]] Inhibits alpha-chymotrypsin at the molar ratio of 1:2 in state of 1:1.		[https://www.uniprot.org/uniprot/ICW3_PSOTE ICW3_PSOTE] Inhibits alpha-chymotrypsin at the molar ratio of 1:2 in state of 1:1.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbc_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Psophocarpus tetragonolobus]]		[[Category: Psophocarpus tetragonolobus]]
	[[Category: Chakrabarti, C]]		[[Category: Chakrabarti C]]
	[[Category: Dattagupta~~, J K~~]]		[[Category: Dattagupta JK]]
	[[Category: Dutta~~, S K~~]]		[[Category: Dutta SK]]
	[[Category: Mukhopadhyay, D]]		[[Category: Mukhopadhyay D]]
	[[Category: Podder, A]]		[[Category: Podder A]]
	[[Category: Sen, U]]		[[Category: Sen U]]
	[[Category: Singh, M]]		[[Category: Singh M]]
	~~[[Category: Serine protease inhibitor~~]]

OCA at 11:02, 6 April 2022

2022-04-06T11:02:42Z

← Older revision		Revision as of 11:02, 6 April 2022
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	<StructureSection load='2wbc' size='340' side='right'caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wbc' size='340' side='right'caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [~~http~~://pdbe.org/2wbc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [https://pdbe.org/2wbc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [https://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/ICW3_PSOTE ICW3_PSOTE]] Inhibits alpha-chymotrypsin at the molar ratio of 1:2 in state of 1:1.		[[https://www.uniprot.org/uniprot/ICW3_PSOTE ICW3_PSOTE]] Inhibits alpha-chymotrypsin at the molar ratio of 1:2 in state of 1:1.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:29, 1 July 2020

2020-07-01T08:29:13Z

← Older revision		Revision as of 08:29, 1 July 2020
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	==REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE==		==REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE==
	<StructureSection load='2wbc' size='340' side='right' caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wbc' size='340' side='right'caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann~~.~~ac.il/oca-docs~~/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://pdbe.org/2wbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://pdbe.org/2wbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	==See Also==		==See Also==
	*[[Chymotrypsin ~~Inhibitor~~\|Chymotrypsin ~~Inhibitor~~]]		*[[Chymotrypsin inhibitor 3D structures\|Chymotrypsin inhibitor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Psophocarpus tetragonolobus]]		[[Category: Psophocarpus tetragonolobus]]
	[[Category: Chakrabarti, C]]		[[Category: Chakrabarti, C]]

OCA at 09:04, 26 September 2018

2018-09-26T09:04:43Z

← Older revision		Revision as of 09:04, 26 September 2018
Line 1:		Line 1:

	==REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE==		==REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE==
	<StructureSection load='2wbc' size='340' side='right' caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='2wbc' size='340' side='right' caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://pdbe.org/2wbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://pdbe.org/2wbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbc_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:43, 9 February 2016

2016-02-09T14:43:15Z

← Older revision		Revision as of 14:43, 9 February 2016
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://pdbe.org/2wbc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wbc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2wbc" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 07:27, 25 December 2014

2014-12-25T07:27:44Z

← Older revision		Revision as of 07:27, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/ICW3_PSOTE ICW3_PSOTE]] Inhibits alpha-chymotrypsin at the molar ratio of 1:2 in state of 1:1.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Psophocarpus tetragonolobus]]		[[Category: Psophocarpus tetragonolobus]]
	[[Category: Chakrabarti, C.]]		[[Category: Chakrabarti, C]]
	[[Category: Dattagupta, J K.]]		[[Category: Dattagupta, J K]]
	[[Category: Dutta, S K.]]		[[Category: Dutta, S K]]
	[[Category: Mukhopadhyay, D.]]		[[Category: Mukhopadhyay, D]]
	[[Category: Podder, A.]]		[[Category: Podder, A]]
	[[Category: Sen, U.]]		[[Category: Sen, U]]
	[[Category: Singh, M.]]		[[Category: Singh, M]]
	[[Category: Serine protease inhibitor]]		[[Category: Serine protease inhibitor]]

OCA at 07:33, 29 September 2014

2014-09-29T07:33:05Z

← Older revision		Revision as of 07:33, 29 September 2014
Line 1:		Line 1:
	[[Image:~~2wbc~~.~~png~~\|~~left~~\|~~200px~~]]		==REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE==
			<StructureSection load='2wbc' size='340' side='right' caption='[[2wbc]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WBC FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wbc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wbc RCSB], [http://www.ebi.ac.uk/pdbsum/2wbc PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wb/2wbc_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The crystal structure of a double-headed alpha-chymotrypsin inhibitor, WCI, from winged bean seeds has now been refined at 2.3 A resolution to an R-factor of 18.7% for 9,897 reflections. The crystals belong to the hexagonal space group P6(1)22 with cell parameters a = b = 61.8 A and c = 212.8 A. The final model has a good stereochemistry and a root mean square deviation of 0.011 A and 1.14 degrees from ideality for bond length and bond angles, respectively. A total of 109 ordered solvent molecules were localized in the structure. This improved structure at 2.3 A led to an understanding of the mechanism of inhibition of the protein against alpha-chymotrypsin. An analysis of this higher resolution structure also helped us to predict the location of the second reactive site of the protein, about which no previous biochemical information was available. The inhibitor structure is spherical and has twelve anti-parallel beta-strands with connecting loops arranged in a characteristic beta-trefoil fold common to other homologous serine protease inhibitors in the Kunitz (STI) family as well as to some non homologous functionally unrelated proteins. A wide variation in the surface loop regions is seen in the latter ones.

	~~{{STRUCTURE_2wbc\| PDB=2wbc \| SCENE= }}~~		Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site.,Dattagupta JK, Podder A, Chakrabarti C, Sen U, Mukhopadhyay D, Dutta SK, Singh M Proteins. 1999 May 15;35(3):321-31. PMID:10328267<ref>PMID:10328267</ref>

	~~===REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_10328267}}~~

	~~==About this Structure==~~
	~~[[2wbc]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA].~~

	==See Also==		==See Also==
	*[[Chymotrypsin Inhibitor\|Chymotrypsin Inhibitor]]		*[[Chymotrypsin Inhibitor\|Chymotrypsin Inhibitor]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:010328267<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Psophocarpus tetragonolobus]]		[[Category: Psophocarpus tetragonolobus]]
	[[Category: Chakrabarti, C.]]		[[Category: Chakrabarti, C.]]

OCA at 14:11, 20 October 2012

2012-10-20T14:11:16Z

← Older revision		Revision as of 14:11, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[2wbc]] is a 1 chain structure ~~of [[Chymotrypsin Inhibitor]]~~ with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA].		[[2wbc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Psophocarpus_tetragonolobus Psophocarpus tetragonolobus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBC OCA].

	==See Also==		==See Also==

OCA at 14:20, 26 July 2012

2012-07-26T14:20:17Z

← Older revision		Revision as of 14:20, 26 July 2012
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	[[Image:2wbc.png\|left\|200px]]		[[Image:2wbc.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2wbc", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2wbc\| PDB=2wbc \| SCENE= }}		{{STRUCTURE_2wbc\| PDB=2wbc \| SCENE= }}

	===REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE===		===REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_10328267}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 10328267 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_10328267}}		{{ABSTRACT_PUBMED_10328267}}

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	==See Also==		==See Also==
	*[[Chymotrypsin Inhibitor]]		*[[Chymotrypsin Inhibitor\|Chymotrypsin Inhibitor]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~10328267~~</ref><references group="xtra"/>		<ref group="xtra">PMID:010328267</ref><references group="xtra"/>
	[[Category: Psophocarpus tetragonolobus]]		[[Category: Psophocarpus tetragonolobus]]
	[[Category: Chakrabarti, C.]]		[[Category: Chakrabarti, C.]]

OCA: Protected "2wbc" [edit=sysop:move=sysop]

2010-12-26T19:45:01Z

Protected "2wbc" [edit=sysop:move=sysop]

← Older revision	Revision as of 19:45, 26 December 2010
(No difference)