2wc8 - Revision history

OCA at 15:51, 13 December 2023

2023-12-13T15:51:25Z

← Older revision		Revision as of 15:51, 13 December 2023
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	<StructureSection load='2wc8' size='340' side='right'caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right'caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.88Å</td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</div></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [https://pdbe.org/2wc8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wc8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [https://pdbe.org/2wc8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wc8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc8 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/S10AC_HUMAN S10AC_HUMAN] S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. Acts as a monocyte and mast cell chemoattractant. Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. Can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn(2+) from their active sites. Possesses filariacidal and filariastatic activity. Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus.<ref>PMID:11522286</ref> <ref>PMID:17208591</ref> <ref>PMID:18292089</ref> <ref>PMID:19386136</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Human~~]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Blagova~~, E V~~]]		[[Category: Blagova EV]]
	[[Category: Bronstein~~, I B~~]]		[[Category: Bronstein IB]]
	[[Category: Moroz~~, O V~~]]		[[Category: Moroz OV]]
	[[Category: Wilkinson~~, A J~~]]		[[Category: Wilkinson AJ]]
	[[Category: Wilson~~, K S]]~~		[[Category: Wilson KS]]
	~~[[Category: Calcium free]]~~
	~~[[Category: Calcium signalling]]~~
	~~[[Category: Ef-hand]]~~
	~~[[Category: Host-parasite response]]~~
	~~[[Category: Metal binding protein]]~~
	~~[[Category: S100 protein~~]]

OCA at 14:50, 29 December 2021

2021-12-29T14:50:44Z

← Older revision		Revision as of 14:50, 29 December 2021
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	<StructureSection load='2wc8' size='340' side='right'caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right'caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [~~http~~://pdbe.org/2wc8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wc8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [https://pdbe.org/2wc8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wc8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc8 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:26, 27 March 2020

2020-03-27T10:26:51Z

← Older revision		Revision as of 10:26, 27 March 2020
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	==S100A12 complex with zinc in the absence of calcium==		==S100A12 complex with zinc in the absence of calcium==
	<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right'caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>
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	==See Also==		==See Also==
	*[[S100 ~~protein~~\|S100 ~~protein~~]]		*[[S100 proteins 3D structures\|S100 proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
			[[Category: Large Structures]]
	[[Category: Blagova, E V]]		[[Category: Blagova, E V]]
	[[Category: Bronstein, I B]]		[[Category: Bronstein, I B]]

OCA at 09:50, 26 September 2018

2018-09-26T09:50:20Z

← Older revision		Revision as of 09:50, 26 September 2018
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	==S100A12 ~~COMPLEX WITH ZINC IN THE ABSENCE OF CALCIUM~~==
			==S100A12 complex with zinc in the absence of calcium==
	<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://pdbe.org/2wc8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://pdbe.org/2wc8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wc8 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wc8_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/2wc8_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:07, 9 February 2016

2016-02-09T16:07:33Z

← Older revision		Revision as of 16:07, 9 February 2016
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	<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://pdbe.org/2wc8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wc8 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2wc8" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Homo sapiens~~]]		[[Category: Human]]
	[[Category: Blagova, E V]]		[[Category: Blagova, E V]]
	[[Category: Bronstein, I B]]		[[Category: Bronstein, I B]]

OCA at 09:54, 20 January 2015

2015-01-20T09:54:37Z

← Older revision		Revision as of 09:54, 20 January 2015
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	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Blagova, E V.]]		[[Category: Blagova, E V]]
	[[Category: Bronstein, I B.]]		[[Category: Bronstein, I B]]
	[[Category: Moroz, O V.]]		[[Category: Moroz, O V]]
	[[Category: Wilkinson, A J.]]		[[Category: Wilkinson, A J]]
	[[Category: Wilson, K S.]]		[[Category: Wilson, K S]]
	[[Category: Calcium free]]		[[Category: Calcium free]]
	[[Category: Calcium signalling]]		[[Category: Calcium signalling]]

OCA at 06:57, 10 October 2014

2014-10-10T06:57:52Z

← Older revision		Revision as of 06:57, 10 October 2014
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	<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='2wc8' size='340' side='right' caption='[[2wc8]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. <br>		<table><tr><td colspan='2'>[[2wc8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WC8 FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2wcb\|2wcb]], [[1gqm\|1gqm]], [[2wcf\|2wcf]], [[1odb\|1odb]], [[1e8a\|1e8a]], [[2wce\|2wce]]</td></tr>
	<tr~~><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class~~='~~plainlinks~~'~~>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>~~		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum]</span></td></tr>
	~~<tr~~><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wc8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wc8 PDBsum]</span></td></tr>		</table>
	<table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 23:
	The crystal structures of human S100A12 in apo form and in complex with zinc: new insights into S100A12 oligomerisation.,Moroz OV, Blagova EV, Wilkinson AJ, Wilson KS, Bronstein IB J Mol Biol. 2009 Aug 21;391(3):536-51. Epub 2009 Jun 6. PMID:19501594<ref>PMID:19501594</ref>		The crystal structures of human S100A12 in apo form and in complex with zinc: new insights into S100A12 oligomerisation.,Moroz OV, Blagova EV, Wilkinson AJ, Wilson KS, Bronstein IB J Mol Biol. 2009 Aug 21;391(3):536-51. Epub 2009 Jun 6. PMID:19501594<ref>PMID:19501594</ref>

	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>

			==See Also==
			*[[S100 protein\|S100 protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:44, 7 May 2014

2014-05-07T08:44:36Z

@@ Line 1: / Line 1: @@
-[[Image:2wc8.png|left|200px]]
+==S100A12 COMPLEX WITH ZINC IN THE ABSENCE OF CALCIUM==
-<!--
+The crystal structures of human S100A12 in apo form and in complex with zinc: new insights into S100A12 oligomerisation.,Moroz OV, Blagova EV, Wilkinson AJ, Wilson KS, Bronstein IB J Mol Biol. 2009 Aug 21;391(3):536-51. Epub 2009 Jun 6. PMID:19501594<ref>PMID:19501594</ref>
-===S100A12 COMPLEX WITH ZINC IN THE ABSENCE OF CALCIUM===
+From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+</div>
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_19501594}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 19501594 is the PubMed ID number.
+</StructureSection>
 [[Category: Homo sapiens]]
 [[Category: Blagova, E V.]]

OCA at 06:54, 24 August 2011

2011-08-24T06:54:10Z

← Older revision		Revision as of 06:54, 24 August 2011
Line 22:		Line 22:

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19501594~~</ref><ref group="xtra">PMID:~~11134923~~</ref><ref group="xtra">PMID:~~12777802~~</ref><ref group="xtra">PMID:~~11856825~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019501594</ref><ref group="xtra">PMID:011134923</ref><ref group="xtra">PMID:012777802</ref><ref group="xtra">PMID:011856825</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Blagova, E V.]]		[[Category: Blagova, E V.]]
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	[[Category: Metal binding protein]]		[[Category: Metal binding protein]]
	[[Category: S100 protein]]		[[Category: S100 protein]]
	~~[[Category: Zinc]]~~

OCA: Protected "2wc8" [edit=sysop:move=sysop]

2011-03-14T21:17:00Z

Protected "2wc8" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:17, 14 March 2011
(No difference)