2wpy - Revision history

OCA at 10:13, 20 December 2023

2023-12-20T10:13:33Z

← Older revision		Revision as of 10:13, 20 December 2023
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	<StructureSection load='2wpy' size='340' side='right'caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wpy' size='340' side='right'caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPY FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;~~'>[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</~~div~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [https://pdbe.org/2wpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [https://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [https://pdbe.org/2wpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [https://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
			*[[Gcn4 3D Structures\|Gcn4 3D Structures]]
	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]		*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Albrecht, R~~]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: ~~Alvarez, B Hernandez~~]]		[[Category: Albrecht R]]
	[[Category: Hartmann~~, M D~~]]		[[Category: Hartmann MD]]
	[[Category: ~~Lupas, A N~~]]		[[Category: Hernandez Alvarez B]]
	[[Category: ~~Zeth, K~~]]		[[Category: Lupas AN]]
	[[Category: ~~Activator]]~~		[[Category: Zeth K]]
	~~[[Category: Amino-acid biosynthesis]]~~
	~~[[Category: Dna-binding]]~~
	~~[[Category: Ion coordination]]~~
	~~[[Category: Nucleus]]~~
	~~[[Category: Phosphoprotein]]~~
	~~[[Category: Polar core residue]]~~
	~~[[Category: Protein export]]~~
	~~[[Category: Taa]]~~
	~~[[Category: Transcription]]~~
	~~[[Category: Transcription regulation]]~~
	~~[[Category: Trimeric autotransporter adhesin~~]]

OCA at 11:13, 6 April 2022

2022-04-06T11:13:17Z

← Older revision		Revision as of 11:13, 6 April 2022
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	<StructureSection load='2wpy' size='340' side='right'caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wpy' size='340' side='right'caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2WPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</div></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [~~http~~://pdbe.org/2wpy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [https://pdbe.org/2wpy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [https://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:03, 1 July 2020

2020-07-01T09:03:00Z

← Older revision		Revision as of 09:03, 1 July 2020
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	==GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride==		==GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride==
	<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wpy' size='340' side='right'caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2WPY FirstGlance]. <br>		<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WPY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [http://pdbe.org/2wpy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [http://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [http://pdbe.org/2wpy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [http://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
	*[[~~Gcn4~~\|~~Gcn4~~]]		*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Albrecht, R]]		[[Category: Albrecht, R]]
	[[Category: Alvarez, B Hernandez]]		[[Category: Alvarez, B Hernandez]]

OCA at 09:04, 26 September 2018

2018-09-26T09:04:46Z

← Older revision		Revision as of 09:04, 26 September 2018
Line 1:		Line 1:

	==GCN4 ~~LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE~~==		==GCN4 leucine zipper mutant with one VxxNxxx motif coordinating chloride==
	<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 20:41, 11 August 2016

2016-08-11T20:41:05Z

← Older revision		Revision as of 20:41, 11 August 2016
Line 1:		Line 1:

	==GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE==		==GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE==
	<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
Line 6:		Line 7:
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [http://www.ebi.ac.uk/pdbsum/2wpy PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [http://pdbe.org/2wpy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [http://www.ebi.ac.uk/pdbsum/2wpy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2wpy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:37, 22 January 2015

2015-01-22T06:37:42Z

← Older revision		Revision as of 06:37, 22 January 2015
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>

			==See Also==
			*[[Gcn4\|Gcn4]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Albrecht, R.]]		[[Category: Albrecht, R]]
	[[Category: Alvarez, B Hernandez.]]		[[Category: Alvarez, B Hernandez]]
	[[Category: Hartmann, M D.]]		[[Category: Hartmann, M D]]
	[[Category: Lupas, A N.]]		[[Category: Lupas, A N]]
	[[Category: Zeth, K.]]		[[Category: Zeth, K]]
	[[Category: Activator]]		[[Category: Activator]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]

OCA at 11:26, 20 October 2014

2014-10-20T11:26:06Z

← Older revision		Revision as of 11:26, 20 October 2014
Line 1:		Line 1:
	[[~~Image~~:~~2wpy~~.~~png~~\|~~left~~\|~~200px~~]]		==GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE==
			<StructureSection load='2wpy' size='340' side='right' caption='[[2wpy]], [[Resolution\|resolution]] 1.75Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPY FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1rb5\|1rb5]], [[1gcm\|1gcm]], [[1unt\|1unt]], [[1llm\|1llm]], [[2zta\|2zta]], [[1unw\|1unw]], [[1uo2\|1uo2]], [[2ccf\|2ccf]], [[1ce9\|1ce9]], [[2wg6\|2wg6]], [[1tmz\|1tmz]], [[1zil\|1zil]], [[2ccn\|2ccn]], [[1w5l\|1w5l]], [[1rb6\|1rb6]], [[1zij\|1zij]], [[1unz\|1unz]], [[1w5k\|1w5k]], [[1piq\|1piq]], [[1unx\|1unx]], [[1uny\|1uny]], [[1zik\|1zik]], [[1ysa\|1ysa]], [[1w5h\|1w5h]], [[1ij2\|1ij2]], [[1unv\|1unv]], [[1uo3\|1uo3]], [[2cce\|2cce]], [[1ij0\|1ij0]], [[1w5g\|1w5g]], [[1unu\|1unu]], [[2b22\|2b22]], [[1ld4\|1ld4]], [[2b1f\|2b1f]], [[1uo0\|1uo0]], [[2wg5\|2wg5]], [[1uo1\|1uo1]], [[1swi\|1swi]], [[1w5i\|1w5i]], [[2dgc\|2dgc]], [[1nkn\|1nkn]], [[2d3e\|2d3e]], [[1gcl\|1gcl]], [[1zii\|1zii]], [[1kql\|1kql]], [[1uo5\|1uo5]], [[1rb4\|1rb4]], [[1ihq\|1ihq]], [[1uo4\|1uo4]], [[1ij3\|1ij3]], [[1zta\|1zta]], [[1w5j\|1w5j]], [[1ij1\|1ij1]], [[1dgc\|1dgc]], [[1rb1\|1rb1]], [[1zim\|1zim]], [[1gzl\|1gzl]], [[2bni\|2bni]], [[2wps\|2wps]], [[2wpz\|2wpz]], [[2wq0\|2wq0]], [[2wq3\|2wq3]], [[2wpq\|2wpq]], [[2wq1\|2wq1]], [[2wq2\|2wq2]], [[2wpr\|2wpr]]</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wpy RCSB], [http://www.ebi.ac.uk/pdbsum/2wpy PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Most core residues of coiled coils are hydrophobic. Occasional polar residues are thought to lower stability, but impart structural specificity. The coiled coils of trimeric autotransporter adhesins (TAAs) are conspicuous for their large number of polar residues in position d of the core, which often leads to their prediction as natively unstructured regions. The most frequent residue, asparagine (N@d), can occur in runs of up to 19 consecutive heptads, frequently in the motif [I/V]xxNTxx. In the Salmonella TAA, SadA, the core asparagines form rings of interacting residues with the following threonines, grouped around a central anion. This conformation is observed generally in N@d layers from trimeric coiled coils of known structure. Attempts to impose a different register on the motif show that the asparagines orient themselves specifically into the core, even against conflicting information from flanking domains. When engineered into the GCN4 leucine zipper, N@d layers progressively destabilized the structure, but zippers with 3 N@d layers still folded at high concentration. We propose that N@d layers maintain the coiled coils of TAAs in a soluble, export-competent state during autotransport through the outer membrane. More generally, we think that polar motifs that are both periodic and conserved may often reflect special folding requirements, rather than an unstructured state of the mature proteins.

	~~{{STRUCTURE_2wpy\| PDB=2wpy \| SCENE= }}~~		A coiled-coil motif that sequesters ions to the hydrophobic core.,Hartmann MD, Ridderbusch O, Zeth K, Albrecht R, Testa O, Woolfson DN, Sauer G, Dunin-Horkawicz S, Lupas AN, Alvarez BH Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):16950-5. Epub 2009 Sep 23. PMID:19805097<ref>PMID:19805097</ref>

	~~===GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_19805097}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2wpy]] is~~ a ~~1 chain structure. Full crystallographic information is available from [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=2WPY OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:019805097<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Albrecht, R.]]		[[Category: Albrecht, R.]]
	[[Category: Alvarez, B Hernandez.]]		[[Category: Alvarez, B Hernandez.]]

OCA: Protected "2wpy" [edit=sysop:move=sysop]

2013-01-07T22:49:55Z

Protected "2wpy" [edit=sysop:move=sysop]

← Older revision	Revision as of 22:49, 7 January 2013
(No difference)

OCA at 22:49, 7 January 2013

2013-01-07T22:49:50Z

← Older revision		Revision as of 22:49, 7 January 2013
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	~~{{Seed}}~~		[[Image:2wpy.png\|left\|200px]]
	[[Image:2wpy.~~jpg~~\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2wpy", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2wpy\| PDB=2wpy \| SCENE= }}		{{STRUCTURE_2wpy\| PDB=2wpy \| SCENE= }}

	===GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE===		===GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_19805097}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 19805097 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_19805097}}		{{ABSTRACT_PUBMED_19805097}}

	==About this Structure==		==About this Structure==
	~~2WPY~~ is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA].		[[2wpy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPY OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19805097~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019805097</ref><references group="xtra"/>
	[[Category: Albrecht, R.]]		[[Category: Albrecht, R.]]
	[[Category: Alvarez, B Hernandez.]]		[[Category: Alvarez, B Hernandez.]]
Line 31:		Line 19:
	[[Category: Activator]]		[[Category: Activator]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]
	~~[[Category: Coiled coil]]~~
	[[Category: Dna-binding]]		[[Category: Dna-binding]]
	[[Category: Ion coordination]]		[[Category: Ion coordination]]
Line 42:		Line 29:
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
	[[Category: Trimeric autotransporter adhesin]]		[[Category: Trimeric autotransporter adhesin]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 4 10:51:12 2009''~~

OCA at 08:51, 4 November 2009

2009-11-04T08:51:13Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 2wpy is ON HOLD  until Paper Publication
+<!--
-Authors: Zeth, K., Hartmann, M.D., Albrecht, R., Lupas, A.N., Hernandez Alvarez, B.
+===GCN4 LEUCINE ZIPPER MUTANT WITH ONE VXXNXXX MOTIF COORDINATING CHLORIDE===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep  3 15:14:30 2009''
+<!--