2xee - Revision history

OCA at 10:29, 20 December 2023

2023-12-20T10:29:45Z

← Older revision		Revision as of 10:29, 20 December 2023
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	<StructureSection load='2xee' size='340' side='right'caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2xee' size='340' side='right'caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Synthetic_construct_sequences~~ Synthetic construct ~~sequences~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [https://pdbe.org/2xee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [https://www.ebi.ac.uk/pdbsum/2xee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [https://pdbe.org/2xee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [https://www.ebi.ac.uk/pdbsum/2xee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Synthetic construct ~~sequences~~]]		[[Category: Synthetic construct]]
	[[Category: Grutter, M]]		[[Category: Grutter M]]
	[[Category: Kramer, M]]		[[Category: Kramer M]]
	[[Category: Mittl, P]]		[[Category: Mittl P]]
	[[Category: Pluckthun, A]]		[[Category: Pluckthun A]]
	[[Category: Wetzel~~, S K]]~~		[[Category: Wetzel SK]]
	~~[[Category: De novo protein]]~~
	~~[[Category: Protein engineering]]~~
	~~[[Category: Protein-protein interaction~~]]

OCA at 10:51, 13 April 2022

2022-04-13T10:51:14Z

← Older revision		Revision as of 10:51, 13 April 2022
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	<StructureSection load='2xee' size='340' side='right'caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2xee' size='340' side='right'caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2XEE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XEE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [~~http~~://pdbe.org/2xee PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xee PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [https://pdbe.org/2xee PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [https://www.ebi.ac.uk/pdbsum/2xee PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 15:12, 8 July 2020

2020-07-08T15:12:22Z

← Older revision		Revision as of 15:12, 8 July 2020
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	==Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.==		==Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.==
	<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2xee' size='340' side='right'caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XEE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XEE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca.weizmann~~.~~ac.il/oca-docs~~/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [http://pdbe.org/2xee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [http://www.ebi.ac.uk/pdbsum/2xee PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [http://pdbe.org/2xee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [http://www.ebi.ac.uk/pdbsum/2xee PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Synthetic construct sequences]]		[[Category: Synthetic construct sequences]]
	[[Category: Grutter, M]]		[[Category: Grutter, M]]

OCA at 09:43, 3 October 2018

2018-10-03T09:43:54Z

← Older revision		Revision as of 09:43, 3 October 2018
Line 1:		Line 1:

	==~~STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED~~ C-~~CAPPING MODULE~~.==		==Structural Determinants for Improved Thermal Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.==
	<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xe/2xee_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xe/2xee_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:19, 11 August 2016

2016-08-11T11:19:21Z

← Older revision		Revision as of 11:19, 11 August 2016
Line 1:		Line 1:

	==STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.==		==STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.==
	<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Synthetic_construct~~ Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEE FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEE FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [http://www.ebi.ac.uk/pdbsum/2xee PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [http://pdbe.org/2xee PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [http://www.ebi.ac.uk/pdbsum/2xee PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xee ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xee ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2xee" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Synthetic construct]]		[[Category: Synthetic construct sequences]]
	[[Category: Grutter, M]]		[[Category: Grutter, M]]
	[[Category: Kramer, M]]		[[Category: Kramer, M]]

OCA at 08:11, 25 January 2015

2015-01-25T08:11:09Z

← Older revision		Revision as of 08:11, 25 January 2015
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
	[[Category: Grutter, M.]]		[[Category: Grutter, M]]
	[[Category: Kramer, M.]]		[[Category: Kramer, M]]
	[[Category: Mittl, P.]]		[[Category: Mittl, P]]
	[[Category: Pluckthun, A.]]		[[Category: Pluckthun, A]]
	[[Category: Wetzel, S K.]]		[[Category: Wetzel, S K]]
	[[Category: De novo protein]]		[[Category: De novo protein]]
	[[Category: Protein engineering]]		[[Category: Protein engineering]]
	[[Category: Protein-protein interaction]]		[[Category: Protein-protein interaction]]

OCA at 13:11, 22 October 2014

2014-10-22T13:11:52Z

← Older revision		Revision as of 13:11, 22 October 2014
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	[[Image:~~2xee~~.~~png~~\|~~left~~\|~~200px~~]]		==STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.==
			<StructureSection load='2xee' size='340' side='right' caption='[[2xee]], [[Resolution\|resolution]] 2.10Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XEE FirstGlance]. <br>
			</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xee FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xee OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xee RCSB], [http://www.ebi.ac.uk/pdbsum/2xee PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xe/2xee_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Designed ankyrin-repeat proteins (DARPins) that specifically bind to almost any target can be obtained by ribosome display or phage display from combinatorial libraries. Although DARPins are already very stable molecules, molecular dynamics simulations, equilibrium denaturation experiments, structural studies, and recent NMR experiments suggested that the unfolding of the original C-terminal capping repeat (C-cap), taken from a natural ankyrin repeat protein, limits the stability of the initial DARPin design. Several point mutations had been introduced to optimize the C-cap and were shown to indeed further increase the stability of DARPins. We now determined crystal structures of DARPins with one or three full-consensus internal repeats (NI(1)C or NI(3)C) between an N-cap and mutants of the C-cap. An NI(1)C mutant, in which the C-cap was only extended by three additional helix-forming residues, showed no structural change, but reduced B-factors in the C-cap. An NI(3)C C-cap mutant carrying five additional mutations in the interface to the preceding repeat, previously designed by using the consensus sequence as a guide, showed a rigid body movement of the C-cap towards the internal repeat. This movement results in an increased buried surface area, a superior surface complementarity and explains the improved stability in equilibrium unfolding, compared to the original C-cap. A C-cap mutant with three additional mutations introducing suitably spaced charged residues did not show formation of salt bridges, explaining why its stability was not increased further. These structural studies underline the importance of repeat coupling for stability and help in the further design of this protein family.

	~~{{STRUCTURE_2xee\| PDB=2xee \| SCENE= }}~~		Structural Determinants for Improved Stability of Designed Ankyrin Repeat Proteins With a Redesigned C-capping Module.,Kramer MA, Wetzel SK, Pluckthun A, Mittl PR, Grutter MG J Mol Biol. 2010 Sep 16. PMID:20851127<ref>PMID:20851127</ref>

	~~===STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_20851127}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[2xee]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Synthetic_construct Synthetic construct]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:020851127<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
	[[Category: Grutter, M.]]		[[Category: Grutter, M.]]

OCA: Protected "2xee" [edit=sysop:move=sysop]

2013-01-07T21:03:01Z

Protected "2xee" [edit=sysop:move=sysop]

← Older revision	Revision as of 21:03, 7 January 2013
(No difference)

OCA at 21:02, 7 January 2013

2013-01-07T21:02:58Z

← Older revision		Revision as of 21:02, 7 January 2013
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	~~{{Seed}}~~
	[[Image:2xee.png\|left\|200px]]		[[Image:2xee.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2xee", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2xee\| PDB=2xee \| SCENE= }}		{{STRUCTURE_2xee\| PDB=2xee \| SCENE= }}

	===STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.===		===STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_20851127}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 20851127 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_20851127}}		{{ABSTRACT_PUBMED_20851127}}

	==About this Structure==		==About this Structure==
	~~2XEE~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA].		[[2xee]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20851127~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020851127</ref><references group="xtra"/>
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
	[[Category: Grutter, M.]]		[[Category: Grutter, M.]]
Line 33:		Line 21:
	[[Category: Protein engineering]]		[[Category: Protein engineering]]
	[[Category: Protein-protein interaction]]		[[Category: Protein-protein interaction]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:41:31 2010''~~

OCA at 04:32, 29 September 2010

2010-09-29T04:32:17Z

← Older revision		Revision as of 04:32, 29 September 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
	[[Image:2xee.~~jpg~~\|left\|200px]]		[[Image:2xee.png\|left\|200px]]

	<!--		<!--
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	===STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.===		===STRUCTURAL DETERMINANTS FOR IMPROVED THERMAL STABILITY OF DESIGNED ANKYRIN REPEAT PROTEINS WITH A REDESIGNED C-CAPPING MODULE.===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_20851127}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 20851127 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20851127}}

	==About this Structure==		==About this Structure==
	2XEE is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA].		2XEE is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XEE OCA].

			==Reference==
			<ref group="xtra">PMID:20851127</ref><references group="xtra"/>
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
	[[Category: Grutter, M.]]		[[Category: Grutter, M.]]
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	[[Category: Protein-protein interaction]]		[[Category: Protein-protein interaction]]

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