2xtb - Revision history

OCA at 13:59, 1 February 2024

2024-02-01T13:59:27Z

← Older revision		Revision as of 13:59, 1 February 2024
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	<StructureSection load='2xtb' size='340' side='right'caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2xtb' size='340' side='right'caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Trybr Trybr~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XTB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XTB FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=KRM:4~~-[~~5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL~~]~~MORPHOLINE'>KRM</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number~~ [~~https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20~~] </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [https://pdbe.org/2xtb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [https://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [https://pdbe.org/2xtb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [https://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q584S0_TRYB2 Q584S0_TRYB2]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Adenosine kinase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Trybr~~]]		[[Category: Trypanosoma brucei rhodesiense]]
	[[Category: Ahmed, S]]		[[Category: Ahmed S]]
	[[Category: Greenwald, J]]		[[Category: Greenwald J]]
	[[Category: Kostrewa, D]]		[[Category: Kostrewa D]]
	[[Category: Kuettel, S]]		[[Category: Kuettel S]]
	[[Category: Perozzo, R]]		[[Category: Perozzo R]]
	[[Category: Scapozza, L]]		[[Category: Scapozza L]]
	~~[[Category: Transferase~~]]

OCA at 12:16, 27 April 2022

2022-04-27T12:16:56Z

← Older revision		Revision as of 12:16, 27 April 2022
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	<StructureSection load='2xtb' size='340' side='right'caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2xtb' size='340' side='right'caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=2XTB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XTB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [~~http~~://pdbe.org/2xtb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [https://pdbe.org/2xtb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [https://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:20, 22 July 2020

2020-07-22T12:20:11Z

← Older revision		Revision as of 12:20, 22 July 2020
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	==Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Activator==		==Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Activator==
	<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2xtb' size='340' side='right'caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2XTB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XTB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [http://pdbe.org/2xtb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [http://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [http://pdbe.org/2xtb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [http://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
	*[[Adenosine kinase\|Adenosine kinase]]		*[[Adenosine kinase 3D structures\|Adenosine kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
			[[Category: Large Structures]]
	[[Category: Trybr]]		[[Category: Trybr]]
	[[Category: Ahmed, S]]		[[Category: Ahmed, S]]

OCA at 08:48, 10 October 2018

2018-10-10T08:48:55Z

← Older revision		Revision as of 08:48, 10 October 2018
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	==~~CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR~~==		==Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Activator==
	<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==

OCA at 08:28, 4 August 2016

2016-08-04T08:28:39Z

← Older revision		Revision as of 08:28, 4 August 2016
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR==		==CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR==
	<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XTB FirstGlance]. <br>		<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybr Trybr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XTB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [http://www.ebi.ac.uk/pdbsum/2xtb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [http://pdbe.org/2xtb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [http://www.ebi.ac.uk/pdbsum/2xtb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xtb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 2xtb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
	[[Category: ~~Trypanosoma brucei rhodesiense~~]]		[[Category: Trybr]]
	[[Category: Ahmed, S]]		[[Category: Ahmed, S]]
	[[Category: Greenwald, J]]		[[Category: Greenwald, J]]

OCA at 13:11, 18 December 2014

2014-12-18T13:11:55Z

← Older revision		Revision as of 13:11, 18 December 2014
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	~~{{STRUCTURE_2xtb\| PDB=2xtb \| SCENE= }}~~		==CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR==
	===CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR===		<StructureSection load='2xtb' size='340' side='right' caption='[[2xtb]], [[Resolution\|resolution]] 2.80Å' scene=''>
	~~{{ABSTRACT_PUBMED_21629723}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[2xtb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XTB FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KRM:4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE'>KRM</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xtb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xtb RCSB], [http://www.ebi.ac.uk/pdbsum/2xtb PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			BACKGROUND: The essential purine salvage pathway of Trypanosoma brucei bears interesting catalytic enzymes for chemotherapeutic intervention of Human African Trypanosomiasis. Unlike mammalian cells, trypanosomes lack de novo purine synthesis and completely rely on salvage from their hosts. One of the key enzymes is adenosine kinase which catalyzes the phosphorylation of ingested adenosine to form adenosine monophosphate (AMP) utilizing adenosine triphosphate (ATP) as the preferred phosphoryl donor. METHODS AND FINDINGS: Here, we present the first structures of Trypanosoma brucei rhodesiense adenosine kinase (TbrAK): the structure of TbrAK in complex with the bisubstrate inhibitor P(1),P(5)-di(adenosine-5')-pentaphosphate (AP5A) at 1.55 A, and TbrAK complexed with the recently discovered activator 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine (compound 1) at 2.8 A resolution. CONCLUSIONS: The structural details and their comparison give new insights into substrate and activator binding to TbrAK at the molecular level. Further structure-activity relationship analyses of a series of derivatives of compound 1 support the observed binding mode of the activator and provide a possible mechanism of action with respect to their activating effect towards TbrAK.

	~~==About this Structure==~~		Crystal Structures of T. b. rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation.,Kuettel S, Greenwald J, Kostrewa D, Ahmed S, Scapozza L, Perozzo R PLoS Negl Trop Dis. 2011 May;5(5):e1164. Epub 2011 May 24. PMID:21629723<ref>PMID:21629723</ref>
	~~[[2xtb]] is a 1 chain structure~~ with ~~sequence from [http~~:~~//en.wikipedia~~.~~org/wiki/Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense]~~. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann~~.~~ac.il/oca-bin~~/~~ocashort?id=2XTB OCA].~~

	==~~Reference~~==		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~<ref group~~=~~"xtra">PMID:021629723</ref>~~<references ~~group="xtra"~~/><~~references~~/>		</div>

			==See Also==
			*[[Adenosine kinase\|Adenosine kinase]]
			== References ==
			<references/>
			__TOC__
			</StructureSection>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
	[[Category: Trypanosoma brucei rhodesiense]]		[[Category: Trypanosoma brucei rhodesiense]]
	[[Category: Ahmed, S.]]		[[Category: Ahmed, S]]
	[[Category: Greenwald, J.]]		[[Category: Greenwald, J]]
	[[Category: Kostrewa, D.]]		[[Category: Kostrewa, D]]
	[[Category: Kuettel, S.]]		[[Category: Kuettel, S]]
	[[Category: Perozzo, R.]]		[[Category: Perozzo, R]]
	[[Category: Scapozza, L.]]		[[Category: Scapozza, L]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 08:11, 2 May 2013

2013-05-02T08:11:15Z

← Older revision		Revision as of 08:11, 2 May 2013
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	~~[[Image:2xtb.jpg\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_2xtb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_2xtb\| PDB=2xtb \| SCENE= }}		{{STRUCTURE_2xtb\| PDB=2xtb \| SCENE= }}

	===CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR===		===CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_21629723}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 21629723 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_21629723}}		{{ABSTRACT_PUBMED_21629723}}

Line 22:		Line 7:

	==Reference==		==Reference==
	<ref group="xtra">PMID:021629723</ref><references group="xtra"/>		<ref group="xtra">PMID:021629723</ref><references group="xtra"/><references/>
	[[Category: Adenosine kinase]]		[[Category: Adenosine kinase]]
	[[Category: Trypanosoma brucei rhodesiense]]		[[Category: Trypanosoma brucei rhodesiense]]

OCA: Protected "2xtb" [edit=sysop:move=sysop]

2011-06-29T06:01:45Z

Protected "2xtb" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:01, 29 June 2011
(No difference)

OCA at 06:01, 29 June 2011

2011-06-29T06:01:41Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+[[Image:2xtb.jpg|left|200px]]
-The entry 2xtb is ON HOLD  until Paper Publication
+<!--
-Authors: Kuettel, S., Greenwald, J., Kostrewa, D., Ahmed, S., Riek, R., Scapozza, L., Perozzo, R.
+===CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI RHODESIENSE ADENOSINE KINASE COMPLEXED WITH ACTIVATOR===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  3 09:56:26 2010''
+<!--

OCA at 06:45, 3 November 2010

2010-11-03T06:45:47Z

← Older revision		Revision as of 06:45, 3 November 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 2xtb is ON HOLD		The entry 2xtb is ON HOLD until Paper Publication

	Authors: Kuettel, S., Greenwald, J., Kostrewa, D., Ahmed, S., Riek, R., Scapozza, L., Perozzo, R.		Authors: Kuettel, S., Greenwald, J., Kostrewa, D., Ahmed, S., Riek, R., Scapozza, L., Perozzo, R.

	Description: Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with ~~Inhibitor~~		Description: Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Activator

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 13 10~~:25:22 2010''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 3 09:56:26 2010''