OCA at 10:20, 30 September 2026

2026-09-30T10:20:04Z

← Older revision		Revision as of 10:20, 30 September 2026
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	~~'''Unreleased structure'''~~

	~~The entry~~ 32ea is ~~ON HOLD~~		==Horse spleen Holoferritin 14.5 MGy variable temperature dose series, 130 K==
			<StructureSection load='32ea' size='340' side='right'caption='[[32ea]], [[Resolution\|resolution]] 2.79Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[32ea]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=32EA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=32EA FirstGlance]. <br>
			</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.79Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=32ea FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=32ea OCA], [https://pdbe.org/32ea PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=32ea RCSB], [https://www.ebi.ac.uk/pdbsum/32ea PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=32ea ProSAT]</span></td></tr>
			</table>
			== Function ==
			[https://www.uniprot.org/uniprot/FRIL_HORSE FRIL_HORSE] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The behaviour of the unit-cell volume of crystals of the iron-storage molecule ferritin, both in the apo and the holo form, and of influenza A virus subtype N9 neuraminidase at 100 K and over a controlled cryo-temperature series was investigated. The purpose of this study was to separate out the effects of dose and temperature on the protein by assessing the changes in the unit-cell volume. Over the wide range of X-ray doses examined in this work, the irreversible effect of dose on the unit-cell volume could be distinguished from the reversible (below 160 K) temperature-induced effects. Specific structural damage effects were not reversible.

	~~Authors:~~ Southworth-Davies~~, R.J.~~, Murray~~, J.W.~~, Carmichael, I., Rudino-Pinera, E., Weik, M., Garman~~, E~~.F.		Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.,Southworth-Davies RJ, Murray JW, Carmichael I, Rudino-Pinera E, Weik M, Garman EF Acta Crystallogr D Struct Biol. 2026 Oct 1. doi: 10.1107/S2059798326008612. PMID:42741972<ref>PMID:42741972</ref>

	~~Description~~: ~~Horse spleen Holoferritin 14.5 MGy variable temperature dose series, 130 K~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	[[Category: ~~Unreleased Structures~~]]		</div>
	[[Category: ~~Murray, J.W~~]]		<div class="pdbe-citations 32ea" style="background-color:#fffaf0;"></div>
	[[Category: Carmichael, I]]		== References ==
	[[Category: Garman~~, E.F~~]]		<references/>
	[[Category: ~~Weik, M~~]]		__TOC__
	[[Category: Rudino-Pinera, E]]		</StructureSection>
	[[Category: Southworth-Davies~~, R.J~~]]		[[Category: Equus caballus]]
			[[Category: Large Structures]]
			[[Category: Carmichael I]]
			[[Category: Garman EF]]
			[[Category: Murray JW]]
			[[Category: Rudino-Pinera E]]
			[[Category: Southworth-Davies RJ]]
			[[Category: Weik M]]

OCA: Protected "32ea": Seeded page ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite))

2026-07-15T06:24:29Z

Protected "32ea": Seeded page ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite))

← Older revision	Revision as of 06:24, 15 July 2026
(No difference)

OCA: Created page with "'''Unreleased structure''' The entry 32ea is ON HOLD Authors: Southworth-Davies, R.J., Murray, J.W., Carmichael, I., Rudino-Pinera, E., Weik, M., Garman, E.F. Description: Horse spleen Holoferritin 14.5 MGy variable temperature dose series, 130 K Category: Unreleased Structures Category: Murray, J.W Category: Carmichael, I Category: Garman, E.F Category: Weik, M Category: Rudino-Pinera, E Category: Southworth-Davies, R.J"

2026-07-15T06:24:29Z

Created page with "'''Unreleased structure''' The entry 32ea is ON HOLD Authors: Southworth-Davies, R.J., Murray, J.W., Carmichael, I., Rudino-Pinera, E., Weik, M., Garman, E.F. Description: Horse spleen Holoferritin 14.5 MGy variable temperature dose series, 130 K Category: Unreleased Structures Category: Murray, J.W Category: Carmichael, I Category: Garman, E.F Category: Weik, M Category: Rudino-Pinera, E Category: Southworth-Davies, R.J"

New page

'''Unreleased structure'''

The entry 32ea is ON HOLD

Authors: Southworth-Davies, R.J., Murray, J.W., Carmichael, I., Rudino-Pinera, E., Weik, M., Garman, E.F.

Description: Horse spleen Holoferritin 14.5 MGy variable temperature dose series, 130 K
[[Category: Unreleased Structures]]
[[Category: Murray, J.W]]
[[Category: Carmichael, I]]
[[Category: Garman, E.F]]
[[Category: Weik, M]]
[[Category: Rudino-Pinera, E]]
[[Category: Southworth-Davies, R.J]]

32ea - Revision history

OCA at 10:20, 30 September 2026

OCA: Protected "32ea": Seeded page ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite))