3a2f - Revision history

OCA at 09:41, 6 November 2024

2024-11-06T09:41:02Z

← Older revision		Revision as of 09:41, 6 November 2024
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	<StructureSection load='3a2f' size='340' side='right'caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>		<StructureSection load='3a2f' size='340' side='right'caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43587 Atcc 43587~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A2F FirstGlance]. <br>		<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A2F FirstGlance]. <br>
	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.67Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">pol, PF0212 ([https://www.ncbi.nlm.nih~~.~~gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [https://pdbe.org/3a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [https://www.ebi.ac.uk/pdbsum/3a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2f ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [https://pdbe.org/3a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [https://www.ebi.ac.uk/pdbsum/3a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/DPOL_PYRFU DPOL_PYRFU]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity~~. [[https://www.uniprot.org/uniprot/PCNA_PYRFU PCNA_PYRFU]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication~~.		[https://www.uniprot.org/uniprot/DPOL_PYRFU DPOL_PYRFU] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2f_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	==See Also==		==See Also==
			*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	*[[Proliferating cell nuclear antigen 3D structures\|Proliferating cell nuclear antigen 3D structures]]		*[[Proliferating cell nuclear antigen 3D structures\|Proliferating cell nuclear antigen 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 43587]]~~
	~~[[Category: DNA-directed DNA polymerase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Ishino, Y~~]]		[[Category: Pyrococcus furiosus]]
	[[Category: ~~Morikawa, K~~]]		[[Category: Ishino Y]]
	[[Category: ~~Nishida, H~~]]		[[Category: Morikawa K]]
	[[Category: ~~Dna replication]]~~		[[Category: Nishida H]]
	~~[[Category: Dna-binding]]~~
	~~[[Category: Dna-directed dna polymerase]]~~
	~~[[Category: Endonuclease]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Nuclease]]~~
	~~[[Category: Nucleotidyltransferase]]~~
	~~[[Category: Transferase]]~~
	~~[[Category: Transferase-replication complex~~]]

OCA at 07:22, 10 November 2021

2021-11-10T07:22:01Z

← Older revision		Revision as of 07:22, 10 November 2021
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	==Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex==		==Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex==
	<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>		<StructureSection load='3a2f' size='340' side='right'caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3A2F FirstGlance]. <br>		<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A2F FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [~~http~~://pdbe.org/3a2f PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3a2f PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2f ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [https://pdbe.org/3a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [https://www.ebi.ac.uk/pdbsum/3a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/DPOL_PYRFU DPOL_PYRFU]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. [[~~http~~://www.uniprot.org/uniprot/PCNA_PYRFU PCNA_PYRFU]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.		[[https://www.uniprot.org/uniprot/DPOL_PYRFU DPOL_PYRFU]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. [[https://www.uniprot.org/uniprot/PCNA_PYRFU PCNA_PYRFU]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
	*[[DNA polymerase\|DNA polymerase]]		*[[Proliferating cell nuclear antigen 3D structures\|Proliferating cell nuclear antigen 3D structures]]
	*[[Proliferating ~~Cell Nuclear Antigen~~\|Proliferating ~~Cell Nuclear Antigen~~]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43587]]		[[Category: Atcc 43587]]
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
			[[Category: Large Structures]]
	[[Category: Ishino, Y]]		[[Category: Ishino, Y]]
	[[Category: Morikawa, K]]		[[Category: Morikawa, K]]

OCA at 06:54, 18 October 2018

2018-10-18T06:54:19Z

← Older revision		Revision as of 06:54, 18 October 2018
Line 1:		Line 1:

	==Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex==		==Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex==
	<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>		<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [http://pdbe.org/3a2f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [http://www.ebi.ac.uk/pdbsum/3a2f PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [http://pdbe.org/3a2f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [http://www.ebi.ac.uk/pdbsum/3a2f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2f ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2f_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2f_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:52, 10 February 2016

2016-02-10T05:52:46Z

← Older revision		Revision as of 05:52, 10 February 2016
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	<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>		<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus Pyrococcus furiosus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2F FirstGlance]. <br>		<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43587 Atcc 43587]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2F FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ~~Pyrococcus furiosus~~]), pcn, PF0983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ~~Pyrococcus furiosus~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587]), pcn, PF0983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 ATCC 43587])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [http://www.ebi.ac.uk/pdbsum/3a2f PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [http://pdbe.org/3a2f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [http://www.ebi.ac.uk/pdbsum/3a2f PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a2f ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Atcc 43587]]
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	~~[[Category: Pyrococcus furiosus]]~~
	[[Category: Ishino, Y]]		[[Category: Ishino, Y]]
	[[Category: Morikawa, K]]		[[Category: Morikawa, K]]

OCA at 12:16, 25 December 2014

2014-12-25T12:16:01Z

← Older revision		Revision as of 12:16, 25 December 2014
Line 1:		Line 1:
	~~[[Image:3a2f.png\|left\|200px]]~~		==Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex==
			<StructureSection load='3a2f' size='340' side='right' caption='[[3a2f]], [[Resolution\|resolution]] 2.67Å' scene=''>
	~~{{STRUCTURE_3a2f\| PDB=3a2f \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3a2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A2F FirstGlance]. <br>
	===Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex===		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol, PF0212 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus]), pcn, PF0983 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr>
	~~{{ABSTRACT_PUBMED_019934045}}~~		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3a2f RCSB], [http://www.ebi.ac.uk/pdbsum/3a2f PDBsum]</span></td></tr>
	==~~About this Structure~~==		</table>
	[[3a2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].		== Function ==
			[[http://www.uniprot.org/uniprot/DPOL_PYRFU DPOL_PYRFU]] In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. [[http://www.uniprot.org/uniprot/PCNA_PYRFU PCNA_PYRFU]] Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2f_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[DNA polymerase\|DNA polymerase]]		*[[DNA polymerase\|DNA polymerase]]
	*[[Proliferating Cell Nuclear Antigen\|Proliferating Cell Nuclear Antigen]]		*[[Proliferating Cell Nuclear Antigen\|Proliferating Cell Nuclear Antigen]]
			__TOC__
	~~==Reference==~~		</StructureSection>
	~~<ref group="xtra">PMID:019934045</ref>~~<~~references group="xtra"~~/>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
	[[Category: Ishino, Y.]]		[[Category: Ishino, Y]]
	[[Category: Morikawa, K.]]		[[Category: Morikawa, K]]
	[[Category: Nishida, H.]]		[[Category: Nishida, H]]
	[[Category: Dna replication]]		[[Category: Dna replication]]
	[[Category: Dna-binding]]		[[Category: Dna-binding]]

OCA at 16:33, 20 October 2012

2012-10-20T16:33:14Z

← Older revision		Revision as of 16:33, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[3a2f]] is a 2 chain structure ~~of [[DNA polymerase]] and [[Proliferating Cell Nuclear Antigen]]~~ with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].		[[3a2f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].

	==See Also==		==See Also==

OCA: Protected "3a2f" [edit=sysop:move=sysop]

2012-07-26T22:03:31Z

Protected "3a2f" [edit=sysop:move=sysop]

← Older revision	Revision as of 22:03, 26 July 2012
(No difference)

OCA at 22:03, 26 July 2012

2012-07-26T22:03:29Z

← Older revision		Revision as of 22:03, 26 July 2012
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	~~{{Seed}}~~
	[[Image:3a2f.png\|left\|200px]]		[[Image:3a2f.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3a2f", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3a2f\| PDB=3a2f \| SCENE= }}		{{STRUCTURE_3a2f\| PDB=3a2f \| SCENE= }}

	===Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex===		===Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex===

			{{ABSTRACT_PUBMED_019934045}}

	==About this Structure==		==About this Structure==
	~~3A2F~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].		[[3a2f]] is a 2 chain structure of [[DNA polymerase]] and [[Proliferating Cell Nuclear Antigen]] with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].

			==See Also==
			*[[DNA polymerase\|DNA polymerase]]
			*[[Proliferating Cell Nuclear Antigen\|Proliferating Cell Nuclear Antigen]]

			==Reference==
			<ref group="xtra">PMID:019934045</ref><references group="xtra"/>
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
Line 28:		Line 29:
	[[Category: Nucleotidyltransferase]]		[[Category: Nucleotidyltransferase]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Transferase/replication complex]]		[[Category: Transferase-replication complex]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 1 14:49:06 2010''~~

OCA at 12:49, 1 February 2010

2010-02-01T12:49:06Z

← Older revision		Revision as of 12:49, 1 February 2010
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	{{Seed}}		{{Seed}}
	[[Image:3a2f.~~jpg~~\|left\|200px]]		[[Image:3a2f.png\|left\|200px]]

	<!--		<!--
Line 14:		Line 14:

	==About this Structure==		==About this Structure==
	3A2F is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].		3A2F is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2F OCA].
	[[Category: DNA-directed DNA polymerase]]		[[Category: DNA-directed DNA polymerase]]
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
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	[[Category: Transferase/replication complex]]		[[Category: Transferase/replication complex]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ ~~4 10~~:53:~~17 2009~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 1 14:49:06 2010''

OCA at 08:53, 4 November 2009

2009-11-04T08:53:18Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3a2f is ON HOLD  until Paper Publication
+<!--
-Authors: Nishida, H., Ishino, Y., Morikawa, K.
+===Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 12:20:28 2009''
+==About this Structure==