3bas - Revision history

OCA at 12:05, 30 August 2023

2023-08-30T12:05:45Z

← Older revision		Revision as of 12:05, 30 August 2023
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	<StructureSection load='3bas' size='340' side='right'caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bas' size='340' side='right'caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Argir Argir~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BAS FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Argopecten_irradians Argopecten irradians] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BAS FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3bat\|3bat]], [[1nkn\|1nkn]]~~<~~/div></td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [https://pdbe.org/3bas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [https://www.ebi.ac.uk/pdbsum/3bas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bas ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [https://pdbe.org/3bas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [https://www.ebi.ac.uk/pdbsum/3bas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bas ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.		[https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'.[https://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
			*[[Gcn4 3D Structures\|Gcn4 3D Structures]]
	*[[Gnc4 3D Structures\|Gnc4 3D Structures]]		*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
	*[[Myosin 3D Structures\|Myosin 3D Structures]]		*[[Myosin 3D Structures\|Myosin 3D Structures]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Argir~~]]		[[Category: Argopecten irradians]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Brown, J H~~]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: ~~Cohen, C~~]]		[[Category: Brown JH]]
	[[Category: ~~Actin-binding]]~~		[[Category: Cohen C]]
	~~[[Category: Alpha-helical coiled coil]]~~
	~~[[Category: Atp-binding]]~~
	~~[[Category: Calmodulin-binding]]~~
	~~[[Category: Contractile protein]]~~
	~~[[Category: Cytoplasm]]~~
	~~[[Category: Disorder]]~~
	~~[[Category: Motor protein]]~~
	~~[[Category: Muscle protein]]~~
	~~[[Category: Myosin]]~~
	~~[[Category: Nucleotide-binding]]~~
	~~[[Category: Salt link]]~~
	~~[[Category: Thick filament~~]]

OCA at 11:29, 5 January 2022

2022-01-05T11:29:40Z

← Older revision		Revision as of 11:29, 5 January 2022
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	==Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form==		==Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form==
	<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bas' size='340' side='right'caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Argir Argir]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BAS FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Argir Argir]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BAS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3bat\|3bat]], [[1nkn\|1nkn]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [~~http~~://pdbe.org/3bas PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3bas PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3bas ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [https://pdbe.org/3bas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [https://www.ebi.ac.uk/pdbsum/3bas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bas ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.		[[https://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3bas_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3bas_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</div>		</div>
	<div class="pdbe-citations 3bas" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3bas" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Gnc4 3D Structures\|Gnc4 3D Structures]]
			*[[Myosin 3D Structures\|Myosin 3D Structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Argir]]		[[Category: Argir]]
			[[Category: Large Structures]]
	[[Category: Brown, J H]]		[[Category: Brown, J H]]
	[[Category: Cohen, C]]		[[Category: Cohen, C]]

OCA at 07:58, 25 October 2017

2017-10-25T07:58:55Z

← Older revision		Revision as of 07:58, 25 October 2017
Line 1:		Line 1:

	==Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form==		==Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form==
	<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://pdbe.org/3bas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://pdbe.org/3bas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bas ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 3bas" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3bas" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Gcn4\|Gcn4]]
	*[[Myosin\|Myosin]]
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Calmodulin-binding]]		[[Category: Calmodulin-binding]]
	[[Category: Contractile protein]]		[[Category: Contractile protein]]
			[[Category: Cytoplasm]]
	[[Category: Disorder]]		[[Category: Disorder]]
	[[Category: Motor protein]]		[[Category: Motor protein]]

OCA at 19:46, 7 February 2016

2016-02-07T19:46:07Z

← Older revision		Revision as of 19:46, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BAS FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Argir Argir]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BAS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~4932 Saccharomyces cerevisiae~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31199 ARGIR])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://pdbe.org/3bas PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~MYS_AEQIR MYS_AEQIR~~]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.		[[http://www.uniprot.org/uniprot/MYS_ARGIR MYS_ARGIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bas ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3bas" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Saccharomyces cerevisiae~~]]		[[Category: Argir]]
	[[Category: Brown, J H]]		[[Category: Brown, J H]]
	[[Category: Cohen, C]]		[[Category: Cohen, C]]

OCA at 17:48, 24 December 2014

2014-12-24T17:48:45Z

← Older revision		Revision as of 17:48, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BAS FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BAS FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/MYS_AEQIR MYS_AEQIR]] Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Brown, J H.]]		[[Category: Brown, J H]]
	[[Category: Cohen, C.]]		[[Category: Cohen, C]]
	[[Category: Actin-binding]]		[[Category: Actin-binding]]
	[[Category: Alpha-helical coiled coil]]		[[Category: Alpha-helical coiled coil]]

OCA at 07:08, 29 September 2014

2014-09-29T07:08:10Z

← Older revision		Revision as of 07:08, 29 September 2014
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	[[Image:~~3bas~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form==
			<StructureSection load='3bas' size='340' side='right' caption='[[3bas]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BAS FirstGlance]. <br>
			</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3bat\|3bat]], [[1nkn\|1nkn]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">-/GCN4, AAS3, ARG9, YEL009C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
			<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bas OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bas RCSB], [http://www.ebi.ac.uk/pdbsum/3bas PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3bas_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The N-terminal region of myosin's rod-like subfragment 2 (S2) joins the two heads of this dimeric molecule and is key to its function. Previously, a crystal structure of this predominantly coiled-coil region was determined for a short fragment (51 residues plus a leucine zipper) of the scallop striated muscle myosin isoform. In that study, the N-terminal 10-14 residues were found to be disordered. We have now determined the structure of the same scallop peptide in three additional crystal environments. In each of two of these structures, improved order has allowed visualization of the entire N-terminus in one chain of the dimeric peptide. We have also compared the melting temperatures of this scallop S2 peptide with those of analogous peptides from three other isoforms. Taken together, these experiments, along with examination of sequences, point to a diminished stability of the N-terminal region of S2 in regulated myosins, compared with those myosins whose regulation is thin filament linked. It seems plain that this isoform-specific instability promotes the off-state conformation of the heads in regulated myosins. We also discuss how myosin isoforms with varied thermal stabilities share the basic capacity to transmit force efficiently in order to produce contraction in their on states.

	~~{{STRUCTURE_3bas\| PDB=3bas \| SCENE= }}~~		An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.,Brown JH, Yang Y, Reshetnikova L, Gourinath S, Suveges D, Kardos J, Hobor F, Reutzel R, Nyitray L, Cohen C J Mol Biol. 2008 Feb 1;375(5):1434-43. Epub 2007 Nov 28. PMID:18155233<ref>PMID:18155233</ref>

	~~===Crystal structure~~ of the ~~N-terminal region of the scallop myosin rod, monoclinic (C2) form===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18155233}}~~

	~~==About this Structure==~~
	~~[[3bas]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=3BAS OCA].~~

	==See Also==		==See Also==
			*[[Gcn4\|Gcn4]]
	*[[Myosin\|Myosin]]		*[[Myosin\|Myosin]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:018155233<~~/~~ref~~><~~ref group="xtra">PMID:012867988</ref><ref group="xtra">PMID:017095604</ref><references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Brown, J H.]]		[[Category: Brown, J H.]]

OCA at 07:40, 20 October 2012

2012-10-20T07:40:46Z

← Older revision		Revision as of 07:40, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[3bas]] is a 2 chain structure ~~of [[Myosin]]~~ with sequence from [http://en.wikipedia.org/wiki/~~Argopecten_irradians,_saccharomyces_cerevisiae Argopecten irradians, saccharomyces~~ cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA].		[[3bas]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA].

	==See Also==		==See Also==
Line 15:		Line 15:
	==Reference==		==Reference==
	<ref group="xtra">PMID:018155233</ref><ref group="xtra">PMID:012867988</ref><ref group="xtra">PMID:017095604</ref><references group="xtra"/>		<ref group="xtra">PMID:018155233</ref><ref group="xtra">PMID:012867988</ref><ref group="xtra">PMID:017095604</ref><references group="xtra"/>
	[[Category: ~~Argopecten irradians, saccharomyces~~ cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Brown, J H.]]		[[Category: Brown, J H.]]
	[[Category: Cohen, C.]]		[[Category: Cohen, C.]]

OCA at 17:06, 25 July 2012

2012-07-25T17:06:31Z

← Older revision		Revision as of 17:06, 25 July 2012
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	[[Image:3bas.png\|left\|200px]]		[[Image:3bas.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3bas", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3bas\| PDB=3bas \| SCENE= }}		{{STRUCTURE_3bas\| PDB=3bas \| SCENE= }}

	===Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form===		===Crystal structure of the N-terminal region of the scallop myosin rod, monoclinic (C2) form===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18155233}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18155233 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18155233}}		{{ABSTRACT_PUBMED_18155233}}

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	==See Also==		==See Also==
	*[[Myosin]]		*[[Myosin\|Myosin]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18155233~~</ref><ref group="xtra">PMID:~~12867988~~</ref><ref group="xtra">PMID:~~17095604~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018155233</ref><ref group="xtra">PMID:012867988</ref><ref group="xtra">PMID:017095604</ref><references group="xtra"/>
	[[Category: Argopecten irradians, saccharomyces cerevisiae]]		[[Category: Argopecten irradians, saccharomyces cerevisiae]]
	[[Category: Brown, J H.]]		[[Category: Brown, J H.]]
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	[[Category: Calmodulin-binding]]		[[Category: Calmodulin-binding]]
	[[Category: Contractile protein]]		[[Category: Contractile protein]]
	~~[[Category: Cytoplasm]]~~
	[[Category: Disorder]]		[[Category: Disorder]]
	[[Category: Motor protein]]		[[Category: Motor protein]]

OCA: Protected "3bas" [edit=sysop:move=sysop]

2010-12-26T09:25:10Z

Protected "3bas" [edit=sysop:move=sysop]

← Older revision	Revision as of 09:25, 26 December 2010
(No difference)

OCA at 09:25, 26 December 2010

2010-12-26T09:25:09Z

← Older revision		Revision as of 09:25, 26 December 2010
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	~~{{Seed}}~~
	[[Image:3bas.png\|left\|200px]]		[[Image:3bas.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
	~~3BAS~~ is a 2 ~~chains~~ structure of ~~sequences~~ from [http://en.wikipedia.org/wiki/Argopecten_irradians,_saccharomyces_cerevisiae Argopecten irradians, saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA].		[[3bas]] is a 2 chain structure of [[Myosin]] with sequence from [http://en.wikipedia.org/wiki/Argopecten_irradians,_saccharomyces_cerevisiae Argopecten irradians, saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BAS OCA].

			==See Also==
			*[[Myosin]]

	==Reference==		==Reference==
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	[[Category: Salt link]]		[[Category: Salt link]]
	[[Category: Thick filament]]		[[Category: Thick filament]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 16:05:55 2009''~~