3blb - Revision history

OCA at 05:42, 17 October 2024

2024-10-17T05:42:36Z

← Older revision		Revision as of 05:42, 17 October 2024
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>

OCA at 12:10, 30 August 2023

2023-08-30T12:10:34Z

← Older revision		Revision as of 12:10, 30 August 2023
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	<StructureSection load='3blb' size='340' side='right'caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='3blb' size='340' side='right'caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</div></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [https://pdbe.org/3blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [https://www.ebi.ac.uk/pdbsum/3blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [https://pdbe.org/3blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [https://www.ebi.ac.uk/pdbsum/3blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).		[https://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Drome~~]]		[[Category: Drosophila melanogaster]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]~~		[[Category: Kuntz DA]]
	[[Category: Kuntz~~, D A~~]]		[[Category: Rose DR]]
	[[Category: Rose~~, D R]]~~
	~~[[Category: Glycosidase]]~~
	~~[[Category: Golgi apparatus]]~~
	~~[[Category: Golgi mannosidase]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Membrane]]~~
	~~[[Category: Signal-anchor]]~~
	~~[[Category: Transmembrane~~]]

OCA at 10:46, 12 January 2022

2022-01-12T10:46:03Z

← Older revision		Revision as of 10:46, 12 January 2022
Line 1:		Line 1:

	==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==		==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==
	<StructureSection load='3blb' size='340' side='right' caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='3blb' size='340' side='right'caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [~~http~~://pdbe.org/3blb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3blb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [https://pdbe.org/3blb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [https://www.ebi.ac.uk/pdbsum/3blb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).		[[https://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 24:

	==See Also==		==See Also==
	*[[Mannosidase\|Mannosidase]]		*[[Mannosidase 3D structures\|Mannosidase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Drome]]		[[Category: Drome]]
			[[Category: Large Structures]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
	[[Category: Kuntz, D A]]		[[Category: Kuntz, D A]]

OCA at 08:09, 31 October 2018

2018-10-31T08:09:41Z

← Older revision		Revision as of 08:09, 31 October 2018
Line 16:		Line 16:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 00:46, 5 August 2016

2016-08-05T00:46:15Z

← Older revision		Revision as of 00:46, 5 August 2016
Line 1:		Line 1:

	==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==		==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==
	<StructureSection load='3blb' size='340' side='right' caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='3blb' size='340' side='right' caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Drosophila_melanogaster Drosophila melanogaster~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 ~~Drosophila melanogaster~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [http://www.ebi.ac.uk/pdbsum/3blb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [http://pdbe.org/3blb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [http://www.ebi.ac.uk/pdbsum/3blb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3blb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3blb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

Line 26:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Drosophila melanogaster~~]]		[[Category: Drome]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
	[[Category: Kuntz, D A]]		[[Category: Kuntz, D A]]

OCA at 14:28, 25 December 2014

2014-12-25T14:28:29Z

← Older revision		Revision as of 14:28, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [http://www.ebi.ac.uk/pdbsum/3blb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [http://www.ebi.ac.uk/pdbsum/3blb PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/MAN2_DROME MAN2_DROME]] Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
	[[Category: Kuntz, D A.]]		[[Category: Kuntz, D A]]
	[[Category: Rose, D R.]]		[[Category: Rose, D R]]
	[[Category: Glycosidase]]		[[Category: Glycosidase]]
	[[Category: Golgi apparatus]]		[[Category: Golgi apparatus]]

OCA at 09:10, 29 September 2014

2014-09-29T09:10:17Z

← Older revision		Revision as of 09:10, 29 September 2014
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	~~[[Image:3blb.png\|left\|200px]]~~		==Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution==
			<StructureSection load='3blb' size='340' side='right' caption='[[3blb]], [[Resolution\|resolution]] 1.30Å' scene=''>
	~~{{STRUCTURE_3blb\| PDB=3blb \| SCENE= }}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BLB FirstGlance]. <br>
	===Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution===		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SWA:1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL'>SWA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
			<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hty\|1hty]], [[1hww\|1hww]], [[1hxk\|1hxk]], [[1ps2\|1ps2]], [[1qwn\|1qwn]], [[1qx1\|1qx1]], [[1r33\|1r33]], [[1r34\|1r34]], [[1tqs\|1tqs]], [[1tqt\|1tqt]], [[1tqu\|1tqu]], [[1tqv\|1tqv]], [[1tqw\|1tqw]], [[2alw\|2alw]], [[2f18\|2f18]], [[2f1a\|2f1a]], [[2f1b\|2f1b]], [[2f7o\|2f7o]], [[2f7p\|2f7p]], [[2f7q\|2f7q]], [[2f7r\|2f7r]]</td></tr>
			<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">alpha-Man-II, GmII, CG18802 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
	==~~About this Structure~~==		<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] </span></td></tr>
	[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3blb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3blb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3blb RCSB], [http://www.ebi.ac.uk/pdbsum/3blb PDBsum]</span></td></tr>
			<table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3blb_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Mannosidase\|Mannosidase]]		*[[Mannosidase\|Mannosidase]]
			__TOC__
			</StructureSection>
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]

OCA at 17:49, 20 October 2012

2012-10-20T17:49:38Z

← Older revision		Revision as of 17:49, 20 October 2012
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	==About this Structure==		==About this Structure==
	[[3blb]] is a 1 chain structure ~~of [[Mannosidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].		[[3blb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].

	==See Also==		==See Also==

OCA: Protected "3blb" [edit=sysop:move=sysop]

2012-07-27T02:07:05Z

Protected "3blb" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:07, 27 July 2012
(No difference)

OCA at 02:07, 27 July 2012

2012-07-27T02:07:04Z

← Older revision		Revision as of 02:07, 27 July 2012
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	~~{{Seed}}~~
	[[Image:3blb.png\|left\|200px]]		[[Image:3blb.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3blb", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3blb\| PDB=3blb \| SCENE= }}		{{STRUCTURE_3blb\| PDB=3blb \| SCENE= }}

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	==About this Structure==		==About this Structure==
	~~3BLB~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].		[[3blb]] is a 1 chain structure of [[Mannosidase]] with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLB OCA].

			==See Also==
			*[[Mannosidase\|Mannosidase]]
	[[Category: Drosophila melanogaster]]		[[Category: Drosophila melanogaster]]
	[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]		[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
Line 26:		Line 22:
	[[Category: Signal-anchor]]		[[Category: Signal-anchor]]
	[[Category: Transmembrane]]		[[Category: Transmembrane]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:42:22 2009''~~