3bs8 - Revision history

OCA at 14:50, 1 November 2023

2023-11-01T14:50:09Z

← Older revision		Revision as of 14:50, 1 November 2023
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	<StructureSection load='3bs8' size='340' side='right'caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bs8' size='340' side='right'caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"vibrio_subtilis"_ehrenberg_1835 "vibrio~~ subtilis~~" ehrenberg 1835~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PMP:4~~-~~DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Glutamate~~-1-~~semialdehyde_2,1~~-~~aminomutase Glutamate~~-1-~~semialdehyde 2,1-aminomutase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8]~~ </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [https://pdbe.org/3bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [https://pdbe.org/3bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/GSA_BACSU GSA_BACSU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Vibrio~~ subtilis ~~ehrenberg 1835]]~~		[[Category: Bacillus subtilis]]
	~~[[Category: Glutamate-1-semialdehyde 2,1-aminomutase~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Fan, J]]		[[Category: Fan J]]
	[[Category: Ge, H]]		[[Category: Ge H]]
	[[Category: Niu, L]]		[[Category: Niu L]]
	[[Category: Teng, M]]		[[Category: Teng M]]
	~~[[Category: 1-aminotransferase]]~~
	~~[[Category: Glutamate-1-semialdehyde 2]]~~
	~~[[Category: Isomerase]]~~
	~~[[Category: Porphyrin biosynthesis]]~~
	~~[[Category: Pyridoxal phosphate~~]]

OCA at 06:49, 12 May 2022

2022-05-12T06:49:52Z

← Older revision		Revision as of 06:49, 12 May 2022
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	<StructureSection load='3bs8' size='340' side='right'caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bs8' size='340' side='right'caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [~~http~~://pdbe.org/3bs8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [https://pdbe.org/3bs8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [https://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:19, 5 August 2020

2020-08-05T06:19:41Z

← Older revision		Revision as of 06:19, 5 August 2020
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	==Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis==		==Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis==
	<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bs8' size='340' side='right'caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [http://pdbe.org/3bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [http://pdbe.org/3bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
	*[[Aminomutase\|Aminomutase]]		*[[Aminomutase 3D structures\|Aminomutase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	[[Category: Vibrio subtilis ehrenberg 1835]]		[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
			[[Category: Large Structures]]
	[[Category: Fan, J]]		[[Category: Fan, J]]
	[[Category: Ge, H]]		[[Category: Ge, H]]

OCA at 08:14, 31 October 2018

2018-10-31T08:14:08Z

← Older revision		Revision as of 08:14, 31 October 2018
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	<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"~~bacillus_globigii~~"~~_migula_1900~~ "~~bacillus globigii~~" ~~migula 1900~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus globigii migula 1900~~]]		[[Category: Vibrio subtilis ehrenberg 1835]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
	[[Category: Fan, J]]		[[Category: Fan, J]]

OCA at 20:16, 11 August 2016

2016-08-11T20:16:20Z

← Older revision		Revision as of 20:16, 11 August 2016
Line 1:		Line 1:

	==Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis==		==Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis==
	<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_subtilis Bacillus subtilis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_globigii"_migula_1900 "bacillus globigii" migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bs8 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [http://pdbe.org/3bs8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bs8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bs8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3bs8" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Aminomutase\|Aminomutase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus ~~subtilis~~]]		[[Category: Bacillus globigii migula 1900]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
	[[Category: Fan, J]]		[[Category: Fan, J]]

OCA at 10:40, 25 January 2015

2015-01-25T10:40:46Z

← Older revision		Revision as of 10:40, 25 January 2015
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	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
	[[Category: Fan, J.]]		[[Category: Fan, J]]
	[[Category: Ge, H.]]		[[Category: Ge, H]]
	[[Category: Niu, L.]]		[[Category: Niu, L]]
	[[Category: Teng, M.]]		[[Category: Teng, M]]
	[[Category: 1-aminotransferase]]		[[Category: 1-aminotransferase]]
	[[Category: Glutamate-1-semialdehyde 2]]		[[Category: Glutamate-1-semialdehyde 2]]

OCA at 09:27, 5 November 2014

2014-11-05T09:27:22Z

← Older revision		Revision as of 09:27, 5 November 2014
Line 1:		Line 1:
	[[~~Image~~:3bs8.~~png\|left\|200px~~]]		==Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis==
			<StructureSection load='3bs8' size='340' side='right' caption='[[3bs8]], [[Resolution\|resolution]] 2.30Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BS8 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate-1-semialdehyde_2,1-aminomutase Glutamate-1-semialdehyde 2,1-aminomutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.3.8 5.4.3.8] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bs8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bs8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bs8 RCSB], [http://www.ebi.ac.uk/pdbsum/3bs8 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Glutamate-1-semialdehyde aminotransferase (GSA-AT), also named glutamate-1-semialdehyde aminomutase (GSAM), a pyridoxamine-5'-phosphate (PMP)/pyridoxal-5'-phosphate (PLP) dependent enzyme, catalyses the transamination of the substrate glutamate-1-semialdehyde (GSA) to the product 5-Aminolevulinic acid (ALA) by an unusual intramolecular exchange of amino and oxo groups within the catalytic intermediate 4,5-diaminovalerate (DAVA). This paper presents the crystal structure of GSA-AT from Bacillus subtilis (GSA-AT(Bsu)) in its PMP-bound form at 2.3A resolution. The structure was determined by molecular replacement using the Synechococcus GSAM (GSAM(Syn)) structure as a search model. Unlike the previous reported GSAM/GSA-AT structures, GSA-AT(Bsu) is a symmetric homodimer in the PMP-bound form, which shows the structural symmetry at the gating loop region with open state, as well as identical cofactor (PMP) binding in each monomer. This observation of PMP in combination with an "open" lid supports one characteristic feature for this enzyme, as the catalyzed reaction is believed to be initiated by PMP. Furthermore, the symmetry of GSA-AT(Bsu) structure challenges the previously proposed negative cooperativity between monomers of this enzyme.

	~~{{STRUCTURE_3bs8\| PDB=3bs8 \| SCENE= }}~~		Crystal structure of Glutamate1-semialdehyde aminotransferase from Bacillus subtilis with bound pyridoxamine-5'-phosphate.,Ge H, Lv X, Fan J, Gao Y, Teng M, Niu L Biochem Biophys Res Commun. 2010 Nov 12;402(2):356-60. Epub 2010 Oct 12. PMID:20946885<ref>PMID:20946885</ref>

	~~===Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate~~ From ~~Bacillus subtilis===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_20946885}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[3bs8]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_subtilis Bacillus subtilis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:020946885<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]

OCA: Protected "3bs8" [edit=sysop:move=sysop]

2013-01-07T22:31:05Z

Protected "3bs8" [edit=sysop:move=sysop]

← Older revision	Revision as of 22:31, 7 January 2013
(No difference)

OCA at 22:31, 7 January 2013

2013-01-07T22:31:03Z

← Older revision		Revision as of 22:31, 7 January 2013
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	[[Image:3bs8.png\|left\|200px]]		[[Image:3bs8.png\|left\|200px]]

	~~<!--~~
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	{{STRUCTURE_3bs8\| PDB=3bs8 \| SCENE= }}		{{STRUCTURE_3bs8\| PDB=3bs8 \| SCENE= }}

	===Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis===		===Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis===


	~~<!--~~
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	{{ABSTRACT_PUBMED_20946885}}		{{ABSTRACT_PUBMED_20946885}}

	==About this Structure==		==About this Structure==
	~~3BS8~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA].		[[3bs8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20946885~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020946885</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
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	[[Category: Porphyrin biosynthesis]]		[[Category: Porphyrin biosynthesis]]
	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 12:49:30 2010''~~

OCA at 09:38, 24 November 2010

2010-11-24T09:38:20Z

← Older revision		Revision as of 09:38, 24 November 2010
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	===Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis===		===Crystal structure of Glutamate 1-Semialdehyde Aminotransferase complexed with pyridoxamine-5'-phosphate From Bacillus subtilis===


			<!--
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			(as it appears on PubMed at http://www.pubmed.gov), where 20946885 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20946885}}

	==About this Structure==		==About this Structure==
	3BS8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA].		3BS8 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BS8 OCA].

			==Reference==
			<ref group="xtra">PMID:20946885</ref><references group="xtra"/>
	[[Category: Bacillus subtilis]]		[[Category: Bacillus subtilis]]
	[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]		[[Category: Glutamate-1-semialdehyde 2,1-aminomutase]]
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	[[Category: Teng, M.]]		[[Category: Teng, M.]]
	[[Category: 1-aminotransferase]]		[[Category: 1-aminotransferase]]
	~~[[Category: Cytoplasm]]~~
	[[Category: Glutamate-1-semialdehyde 2]]		[[Category: Glutamate-1-semialdehyde 2]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
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	[[Category: Pyridoxal phosphate]]		[[Category: Pyridoxal phosphate]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Dec~~ 24 11:29:~~15 2008~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 12:49:30 2010''