3dff - Revision history

OCA at 01:43, 21 November 2024

2024-11-21T01:43:23Z

← Older revision		Revision as of 01:43, 21 November 2024
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	<StructureSection load='3dff' size='340' side='right'caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3dff' size='340' side='right'caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"actinoplanes_teichomyceticus"_parenti_et_al._1978 "actinoplanes~~ teichomyceticus~~" parenti et al. 1978~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DFF FirstGlance]. <br>		<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DFF FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~MSE~~:~~SELENOMETHIONINE~~'>~~MSE~~</scene><~~/td></tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td><~~td class~~=~~"sblockDat"><div style~~=~~'overflow~~: ~~auto; max-height: 3em;~~'>~~[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]~~</~~div~~><~~/td></tr>~~
	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></~~td><td class="sblockDat"~~>~~tcp14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])~~</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [https://pdbe.org/3dff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [https://www.ebi.ac.uk/pdbsum/3dff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dff ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [https://pdbe.org/3dff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [https://www.ebi.ac.uk/pdbsum/3dff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dff ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q6ZZJ1_ACTTI Q6ZZJ1_ACTTI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dff_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dff_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Actinoplanes teichomyceticus ~~parenti et al. 1978~~]]		[[Category: Actinoplanes teichomyceticus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Brunzelle~~, J S~~]]		[[Category: Brunzelle JS]]
	[[Category: Nair~~, S K~~]]		[[Category: Nair SK]]
	[[Category: Zou, Y]]		[[Category: Zou Y]]
	~~[[Category: Deacetylase]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Lipoglycopeptide]]~~
	~~[[Category: Pseudoaglycone]]~~
	~~[[Category: Zinc dependent~~]]

OCA at 07:57, 9 February 2022

2022-02-09T07:57:35Z

← Older revision		Revision as of 07:57, 9 February 2022
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	==The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2==		==The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2==
	<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3dff' size='340' side='right'caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"actinoplanes_teichomyceticus"_parenti_et_al._1978 "actinoplanes teichomyceticus" parenti et al. 1978]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3DFF FirstGlance]. <br>		<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"actinoplanes_teichomyceticus"_parenti_et_al._1978 "actinoplanes teichomyceticus" parenti et al. 1978]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DFF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [~~http~~://pdbe.org/3dff PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3dff PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3dff ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [https://pdbe.org/3dff PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [https://www.ebi.ac.uk/pdbsum/3dff PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dff ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Actinoplanes teichomyceticus parenti et al. 1978]]		[[Category: Actinoplanes teichomyceticus parenti et al. 1978]]
			[[Category: Large Structures]]
	[[Category: Brunzelle, J S]]		[[Category: Brunzelle, J S]]
	[[Category: Nair, S K]]		[[Category: Nair, S K]]

OCA at 09:44, 14 November 2018

2018-11-14T09:44:13Z

← Older revision		Revision as of 09:44, 14 November 2018
Line 1:		Line 1:

	==The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2==		==The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2==
	<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [http://pdbe.org/3dff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [http://www.ebi.ac.uk/pdbsum/3dff PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [http://pdbe.org/3dff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [http://www.ebi.ac.uk/pdbsum/3dff PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dff ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dff_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dff_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 17:11, 7 February 2016

2016-02-07T17:11:13Z

← Older revision		Revision as of 17:11, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Actinoplanes_teichomyceticus Actinoplanes~~ teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DFF FirstGlance]. <br>		<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinoplanes_teichomyceticus"_parenti_et_al._1978 "actinoplanes teichomyceticus" parenti et al. 1978]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DFF FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 Actinoplanes teichomyceticus])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 "Actinoplanes teichomyceticus" Parenti et al. 1978])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [http://www.ebi.ac.uk/pdbsum/3dff PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [http://pdbe.org/3dff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [http://www.ebi.ac.uk/pdbsum/3dff PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dff ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3dff" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Actinoplanes teichomyceticus]]		[[Category: Actinoplanes teichomyceticus parenti et al. 1978]]
	[[Category: Brunzelle, J S]]		[[Category: Brunzelle, J S]]
	[[Category: Nair, S K]]		[[Category: Nair, S K]]

OCA at 07:59, 12 November 2014

2014-11-12T07:59:39Z

← Older revision		Revision as of 07:59, 12 November 2014
Line 1:		Line 1:
	[[Image:~~3dff~~.~~png~~\|~~left~~\|~~200px~~]]		==The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2==
			<StructureSection load='3dff' size='340' side='right' caption='[[3dff]], [[Resolution\|resolution]] 1.60Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3dff]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DFF FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
			<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dfi\|3dfi]], [[3dfk\|3dfk]], [[3dfm\|3dfm]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">tcp14 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1867 Actinoplanes teichomyceticus])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dff OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dff RCSB], [http://www.ebi.ac.uk/pdbsum/3dff PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/df/3dff_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The lipoglycopeptide antibiotics teicoplanin and A40926 have proven efficacy against Gram-positive pathogens. These drugs are distinguished from glycopeptide antibiotics by N-linked long chain acyl-D-glucosamine decorations that contribute to antibacterial efficacy. During the biosynthesis of lipoglycopeptides, tailoring glycosyltransferases attach an N-acetyl-D-glucosamine to the aglycone, and this N-acetyl-glucosaminyl pseudoaglycone is deacetylated prior to long chain hydrocarbon attachment. Here we present several high-resolution crystal structures of the pseudoaglycone deacetylases from the biosynthetic pathways of teicoplanin and A40926. The cocrystal structure of the teicoplanin pseudoaglycone deacetylase with a fatty acid product provides further insights into the roles of active-site residues, and suggests mechanistic similarities with structurally distinct zinc deacetylases, such as peptidoglycan deacetylase and LpxC. A unique, structurally mobile capping lid, located at the apex of these pseudoaglycone deacetylases, likely serves as a determinant of substrate specificity.

	~~{{STRUCTURE_3dff\| PDB=3dff \| SCENE= }}~~		Crystal structures of lipoglycopeptide antibiotic deacetylases: implications for the biosynthesis of A40926 and teicoplanin.,Zou Y, Brunzelle JS, Nair SK Chem Biol. 2008 Jun;15(6):533-45. PMID:18559264<ref>PMID:18559264</ref>

	~~===The crystal structure~~ of ~~teicoplanin pseudoaglycone deacetylase Orf2===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_18559264}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[3dff]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:018559264<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Actinoplanes teichomyceticus]]		[[Category: Actinoplanes teichomyceticus]]
	[[Category: Brunzelle, J S.]]		[[Category: Brunzelle, J S]]
	[[Category: Nair, S K.]]		[[Category: Nair, S K]]
	[[Category: Zou, Y.]]		[[Category: Zou, Y]]
	[[Category: Deacetylase]]		[[Category: Deacetylase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA: Protected "3dff" [edit=sysop:move=sysop]

2013-01-07T23:04:55Z

Protected "3dff" [edit=sysop:move=sysop]

← Older revision	Revision as of 23:04, 7 January 2013
(No difference)

OCA at 23:04, 7 January 2013

2013-01-07T23:04:52Z

← Older revision		Revision as of 23:04, 7 January 2013
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	~~{{Seed}}~~
	[[Image:3dff.png\|left\|200px]]		[[Image:3dff.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3dff", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3dff\| PDB=3dff \| SCENE= }}		{{STRUCTURE_3dff\| PDB=3dff \| SCENE= }}

	===The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2===		===The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_18559264}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 18559264 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_18559264}}		{{ABSTRACT_PUBMED_18559264}}

	==About this Structure==		==About this Structure==
	~~3DFF~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA].		[[3dff]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~18559264~~</ref><references group="xtra"/>		<ref group="xtra">PMID:018559264</ref><references group="xtra"/>
	[[Category: Actinoplanes teichomyceticus]]		[[Category: Actinoplanes teichomyceticus]]
	[[Category: Brunzelle, J S.]]		[[Category: Brunzelle, J S.]]
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	[[Category: Pseudoaglycone]]		[[Category: Pseudoaglycone]]
	[[Category: Zinc dependent]]		[[Category: Zinc dependent]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:21:01 2009''~~

OCA at 13:21, 16 February 2009

2009-02-16T13:21:03Z

← Older revision		Revision as of 13:21, 16 February 2009
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	==About this Structure==		==About this Structure==
	3DFF is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA].		3DFF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Actinoplanes_teichomyceticus Actinoplanes teichomyceticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFF OCA].

	==Reference==		==Reference==
	~~Crystal structures of lipoglycopeptide antibiotic deacetylases: implications for the biosynthesis of A40926 and teicoplanin., Zou Y, Brunzelle JS, Nair SK, Chem Biol. 2008 Jun;15(6):533-45.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~18559264 18559264]~~		<ref group="xtra">PMID:18559264</ref><references group="xtra"/>
	[[Category: Actinoplanes teichomyceticus]]		[[Category: Actinoplanes teichomyceticus]]
	~~[[Category: Single protein]]~~
	[[Category: Brunzelle, J S.]]		[[Category: Brunzelle, J S.]]
	[[Category: Nair, S K.]]		[[Category: Nair, S K.]]
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	[[Category: Zinc dependent]]		[[Category: Zinc dependent]]

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	{{STRUCTURE_3dff\| PDB=3dff \| SCENE= }}		{{STRUCTURE_3dff\| PDB=3dff \| SCENE= }}

	===~~Crystal Structures~~ of ~~Lipoglycopeptide Antibiotic Deacetylases: Implications for the Biosynthesis of A40926 and Teicoplanin~~===		===The crystal structure of teicoplanin pseudoaglycone deacetylase Orf2===


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	[[Category: Zinc dependent]]		[[Category: Zinc dependent]]

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OCA at 15:12, 27 July 2008

2008-07-27T15:12:53Z

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	{{Seed}}		{{Seed}}
	[[Image:3dff.~~jpg~~\|left\|200px]]		[[Image:3dff.png\|left\|200px]]

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	[[Category: Zinc dependent]]		[[Category: Zinc dependent]]

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