3ext - Revision history

OCA at 15:24, 1 November 2023

2023-11-01T15:24:08Z

← Older revision		Revision as of 15:24, 1 November 2023
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	<StructureSection load='3ext' size='340' side='right'caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ext' size='340' side='right'caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_25175 Atcc 25175~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXT FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[3exr\|3exr]]~~, [[~~3exs~~\|~~3exs~~]]~~</div>~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>ulaD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1309 ATCC 25175])</td~~><~~/tr>~~
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [https://pdbe.org/3ext PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [https://www.ebi.ac.uk/pdbsum/3ext PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ext ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [https://pdbe.org/3ext PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [https://www.ebi.ac.uk/pdbsum/3ext PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ext ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q93DA8_STRMG Q93DA8_STRMG]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]~~
	~~[[Category: Atcc 25175]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Li, G L~~]]		[[Category: Streptococcus mutans]]
	[[Category: Li~~, L F~~]]		[[Category: Li GL]]
	[[Category: ~~Liu, X~~]]		[[Category: Li LF]]
	[[Category: ~~Su,~~ X D]]		[[Category: Liu X]]
	[[Category: ~~Beta barrel]]~~		[[Category: Su XD]]
	~~[[Category: Lyase~~]]

OCA at 09:19, 23 February 2022

2022-02-23T09:19:06Z

← Older revision		Revision as of 09:19, 23 February 2022
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	==Crystal structure of KGPDC from Streptococcus mutans==		==Crystal structure of KGPDC from Streptococcus mutans==
	<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ext' size='340' side='right'caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3EXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EXT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3exr\|3exr]], [[3exs\|3exs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3exr\|3exr]], [[3exs\|3exs]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [~~http~~://pdbe.org/3ext PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ext PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ext ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [https://pdbe.org/3ext PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [https://www.ebi.ac.uk/pdbsum/3ext PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ext ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]		[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]
	[[Category: Atcc 25175]]		[[Category: Atcc 25175]]
			[[Category: Large Structures]]
	[[Category: Li, G L]]		[[Category: Li, G L]]
	[[Category: Li, L F]]		[[Category: Li, L F]]

OCA at 07:33, 23 May 2018

2018-05-23T07:33:45Z

← Older revision		Revision as of 07:33, 23 May 2018
Line 1:		Line 1:

	==Crystal structure of KGPDC from Streptococcus mutans==		==Crystal structure of KGPDC from Streptococcus mutans==
	<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [http://pdbe.org/3ext PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [http://www.ebi.ac.uk/pdbsum/3ext PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [http://pdbe.org/3ext PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [http://www.ebi.ac.uk/pdbsum/3ext PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ext ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3ext_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3ext_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:47, 7 February 2016

2016-02-07T16:47:41Z

← Older revision		Revision as of 16:47, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_mutans Streptococcus mutans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EXT FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EXT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3exr\|3exr]], [[3exs\|3exs]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3exr\|3exr]], [[3exs\|3exs]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ~~Streptococcus mutans~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [http://www.ebi.ac.uk/pdbsum/3ext PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [http://pdbe.org/3ext PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [http://www.ebi.ac.uk/pdbsum/3ext PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ext ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3ext" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]		[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]
	[[Category: ~~Streptococcus mutans~~]]		[[Category: Atcc 25175]]
	[[Category: Li, G L]]		[[Category: Li, G L]]
	[[Category: Li, L F]]		[[Category: Li, L F]]

OCA at 08:54, 26 November 2014

2014-11-26T08:54:00Z

← Older revision		Revision as of 08:54, 26 November 2014
Line 1:		Line 1:
	[[Image:~~3ext~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of KGPDC from Streptococcus mutans==
			<StructureSection load='3ext' size='340' side='right' caption='[[3ext]], [[Resolution\|resolution]] 2.00Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3ext]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EXT FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3exr\|3exr]], [[3exs\|3exs]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ulaD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydro-L-gulonate-6-phosphate_decarboxylase 3-dehydro-L-gulonate-6-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.85 4.1.1.85] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ext FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ext OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ext RCSB], [http://www.ebi.ac.uk/pdbsum/3ext PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/3ext_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The 3-keto-L-gulonate 6-phosphate decarboxylase (KGPDC) catalyses the decarboxylation of 3-keto-L-gulonate 6-phosphate to L-xylulose in the presence of magnesium ions. The enzyme is involved in L-ascorbate metabolism and plays an essential role in the pathway of glucuronate interconversion. Crystal structures of Streptococcus mutans KGPDC were determined in the absence and presence of the product analog D-ribulose 5-phosphate. We have observed an 8 A alphaB-helix movement and other structural rearrangements around the active site between the apo-structures and product analog bound structure. These drastic conformational changes upon ligand binding are the first observation of this kind for the KGPDC family. The flexibilities of both the alpha-helix lid and the side chains of Arg144 and Arg197 are associated with substrate binding and product releasing. The open-closed conformational changes of the active site, through the movements of the alpha-helix lid and the arginine residues are important for substrate binding and catalysis.

	~~{{STRUCTURE_3ext\| PDB=3ext \| SCENE= }}~~		Open-closed conformational change revealed by the crystal structures of 3-keto-L-gulonate 6-phosphate decarboxylase from Streptococcus mutans.,Li GL, Liu X, Nan J, Brostromer E, Li LF, Su XD Biochem Biophys Res Commun. 2009 Apr 10;381(3):429-33. Epub 2009 Feb 15. PMID:19222992<ref>PMID:19222992</ref>

	~~===Crystal structure~~ of ~~KGPDC from Streptococcus mutans===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_19222992}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[3ext]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_mutans Streptococcus mutans]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:019222992<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]		[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]
	[[Category: Li, G L.]]		[[Category: Li, G L]]
	[[Category: Li, L F.]]		[[Category: Li, L F]]
	[[Category: Liu, X.]]		[[Category: Liu, X]]
	[[Category: Su, X D.]]		[[Category: Su, X D]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA: Protected "3ext" [edit=sysop:move=sysop]

2013-02-06T13:41:41Z

Protected "3ext" [edit=sysop:move=sysop]

← Older revision	Revision as of 13:41, 6 February 2013
(No difference)

OCA at 13:41, 6 February 2013

2013-02-06T13:41:39Z

← Older revision		Revision as of 13:41, 6 February 2013
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	~~{{Seed}}~~
	[[Image:3ext.png\|left\|200px]]		[[Image:3ext.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3ext", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3ext\| PDB=3ext \| SCENE= }}		{{STRUCTURE_3ext\| PDB=3ext \| SCENE= }}

	===Crystal structure of KGPDC from Streptococcus mutans===		===Crystal structure of KGPDC from Streptococcus mutans===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_19222992}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 19222992 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_19222992}}		{{ABSTRACT_PUBMED_19222992}}

	==About this Structure==		==About this Structure==
	~~3EXT~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA].		[[3ext]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EXT OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19222992~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019222992</ref><references group="xtra"/>
	[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]		[[Category: 3-dehydro-L-gulonate-6-phosphate decarboxylase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]
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	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Lyase]]		[[Category: Lyase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:24:28 2009''~~

OCA at 16:24, 21 September 2009

2009-09-21T16:24:30Z

← Older revision		Revision as of 16:24, 21 September 2009
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	===Crystal structure of KGPDC from Streptococcus mutans===		===Crystal structure of KGPDC from Streptococcus mutans===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_19222992}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 19222992 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_19222992}}

	==About this Structure==		==About this Structure==
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	[[Category: Lyase]]		[[Category: Lyase]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 16:48:15 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:24:28 2009''

OCA at 13:48, 21 September 2009

2009-09-21T13:48:15Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3ext is ON HOLD  until Paper Publication
+<!--
-Authors: Li, G.L., Liu, X., Li, L.F., Su, X.D.
+===Crystal structure of KGPDC from Streptococcus mutans===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  5 11:43:24 2008''
+==About this Structure==

OCA at 09:43, 5 November 2008

2008-11-05T09:43:25Z

← Older revision		Revision as of 09:43, 5 November 2008
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3ext is ON HOLD		The entry 3ext is ON HOLD until Paper Publication

	Authors: Li, G.L., Liu, X., Li, L.F., Su, X.D.		Authors: Li, G.L., Liu, X., Li, L.F., Su, X.D.
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	Description: Crystal structure of KGPDC from Streptococcus mutans		Description: Crystal structure of KGPDC from Streptococcus mutans

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 29 10~~:30:09 2008''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 5 11:43:24 2008''