3fvm - Revision history

OCA at 15:32, 1 November 2023

2023-11-01T15:32:25Z

← Older revision		Revision as of 15:32, 1 November 2023
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	<StructureSection load='3fvm' size='340' side='right'caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3fvm' size='340' side='right'caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_43765 Atcc 43765~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3FVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FVM FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8]~~ </~~span~~></td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [~~http~~://pdbe.org/3fvm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3fvm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [https://pdbe.org/3fvm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [https://www.ebi.ac.uk/pdbsum/3fvm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/UXUA_STRSY UXUA_STRSY]] Catalyzes the dehydration of D-mannonate (By similarity).		[https://www.uniprot.org/uniprot/UXUA_STRSY UXUA_STRSY] Catalyzes the dehydration of D-mannonate (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 43765]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Mannonate dehydratase~~]]		[[Category: Streptococcus suis]]
	[[Category: Gao, F]]		[[Category: Gao F]]
	[[Category: Gao~~, F G~~]]		[[Category: Gao FG]]
	[[Category: Liu, Y]]		[[Category: Liu Y]]
	[[Category: Peng, H]]		[[Category: Peng H]]
	[[Category: Zhang~~, Q J]]~~		[[Category: Zhang QJ]]
	~~[[Category: Lyase]]~~
	~~[[Category: Tim barrel]]~~
	~~[[Category: Xylose isomerase-like superfamily~~]]

OCA at 10:32, 9 September 2020

2020-09-09T10:32:30Z

← Older revision		Revision as of 10:32, 9 September 2020
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	==Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++==		==Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++==
	<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3fvm' size='340' side='right'caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43765 Atcc 43765]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3FVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43765 Atcc 43765]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3FVM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://pdbe.org/3fvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://pdbe.org/3fvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 43765]]		[[Category: Atcc 43765]]
			[[Category: Large Structures]]
	[[Category: Mannonate dehydratase]]		[[Category: Mannonate dehydratase]]
	[[Category: Gao, F]]		[[Category: Gao, F]]

OCA at 07:28, 5 December 2018

2018-12-05T07:28:17Z

← Older revision		Revision as of 07:28, 5 December 2018
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	==Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++==		==Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++==
	<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://pdbe.org/3fvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://pdbe.org/3fvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3fvm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvm_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvm_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:08, 7 February 2016

2016-02-07T02:08:39Z

← Older revision		Revision as of 02:08, 7 February 2016
Line 2:		Line 2:
	<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_suis Streptococcus suis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43765 Atcc 43765]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://pdbe.org/3fvm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fvm ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3fvm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Atcc 43765]]
	[[Category: Mannonate dehydratase]]		[[Category: Mannonate dehydratase]]
	~~[[Category: Streptococcus suis]]~~
	[[Category: Gao, F]]		[[Category: Gao, F]]
	[[Category: Gao, F G]]		[[Category: Gao, F G]]

OCA at 06:57, 24 December 2014

2014-12-24T06:57:18Z

← Older revision		Revision as of 06:57, 24 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/UXUA_STRSY UXUA_STRSY]] Catalyzes the dehydration of D-mannonate (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:15, 3 December 2014

2014-12-03T10:15:52Z

← Older revision		Revision as of 10:15, 3 December 2014
Line 1:		Line 1:
	[[Image:~~3fvm~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++==
			<StructureSection load='3fvm' size='340' side='right' caption='[[3fvm]], [[Resolution\|resolution]] 2.90Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FVM FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Mannonate_dehydratase Mannonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.8 4.2.1.8] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fvm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fvm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3fvm RCSB], [http://www.ebi.ac.uk/pdbsum/3fvm PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fv/3fvm_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Mannonate dehydratase (ManD) is found only in certain bacterial species, where it participates in the dissimilation of glucuronate. ManD catalyzes the dehydration of d-mannonate to yield 2-keto-3-deoxygluconate (2-KDG), the carbon and energy source for growth. Selective inactivation of ManD by drug targeting is of therapeutic interest in the treatment of human Streptococcus suis infections. Here, we report the overexpression, purification, functional characterization, and crystallographic structure of ManD from S. suis. Importantly, by Fourier transform mass spectrometry, we show that 2-KDG is formed when the chemically synthesized substrate (d-mannonate) is incubated with ManD. Inductively coupled plasma-mass spectrometry revealed the presence of Mn(2+) in the purified protein, and in the solution state catalytically active ManD exists as a homodimer of two 41-kDa subunits. The crystal structures of S. suis ManD in native form and in complex with its substrate and Mn(2+) ion have been solved at a resolution of 2.9 A. The core structure of S. suis ManD is a TIM barrel similar to that of other members of the xylose isomerase-like superfamily. Structural analyses and comparative amino acid sequence alignments provide evidence for the importance of His311 and Tyr325 in ManD activity. The results of site-directed mutagenesis confirmed the functional role(s) of these residues in the dehydration reaction and a plausible mechanism for the ManD-catalyzed reaction is proposed.

	~~{{STRUCTURE_3fvm\| PDB=3fvm \| SCENE= }}~~		Crystal structures of Streptococcus suis mannonate dehydratase (ManD) and its complex with substrate: genetic and biochemical evidence for a catalytic mechanism.,Zhang Q, Gao F, Peng H, Cheng H, Liu Y, Tang J, Thompson J, Wei G, Zhang J, Du Y, Yan J, Gao GF J Bacteriol. 2009 Sep;191(18):5832-7. Epub 2009 Jul 17. PMID:19617363<ref>PMID:19617363</ref>

	~~===Crystal structure~~ of ~~Steptococcus suis mannonate dehydratase with metal Mn++===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_19617363}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[3fvm]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptococcus_suis Streptococcus suis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:019617363<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Mannonate dehydratase]]		[[Category: Mannonate dehydratase]]
	[[Category: Streptococcus suis]]		[[Category: Streptococcus suis]]
	[[Category: Gao, F.]]		[[Category: Gao, F]]
	[[Category: Gao, F G.]]		[[Category: Gao, F G]]
	[[Category: Liu, Y.]]		[[Category: Liu, Y]]
	[[Category: Peng, H.]]		[[Category: Peng, H]]
	[[Category: Zhang, Q J.]]		[[Category: Zhang, Q J]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Tim barrel]]		[[Category: Tim barrel]]
	[[Category: Xylose isomerase-like superfamily]]		[[Category: Xylose isomerase-like superfamily]]

OCA: Protected "3fvm" [edit=sysop:move=sysop]

2013-02-20T14:33:31Z

Protected "3fvm" [edit=sysop:move=sysop]

← Older revision	Revision as of 14:33, 20 February 2013
(No difference)

OCA at 14:33, 20 February 2013

2013-02-20T14:33:27Z

← Older revision		Revision as of 14:33, 20 February 2013
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	~~{{Seed}}~~		[[Image:3fvm.png\|left\|200px]]
	[[Image:3fvm.~~jpg~~\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3fvm", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3fvm\| PDB=3fvm \| SCENE= }}		{{STRUCTURE_3fvm\| PDB=3fvm \| SCENE= }}

	===Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++===		===Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_19617363}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 19617363 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_19617363}}		{{ABSTRACT_PUBMED_19617363}}

	==About this Structure==		==About this Structure==
	~~3FVM~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA].		[[3fvm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_suis Streptococcus suis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FVM OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19617363~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019617363</ref><references group="xtra"/>
	[[Category: Mannonate dehydratase]]		[[Category: Mannonate dehydratase]]
	[[Category: Streptococcus suis]]		[[Category: Streptococcus suis]]
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	[[Category: Tim barrel]]		[[Category: Tim barrel]]
	[[Category: Xylose isomerase-like superfamily]]		[[Category: Xylose isomerase-like superfamily]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 16:04:59 2009''~~

OCA at 13:05, 3 September 2009

2009-09-03T13:05:01Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3fvm is ON HOLD  until Paper Publication
+<!--
-Authors: Peng, H., Zhang, Q.J., Gao, F., Liu, Y.W., Gao, F.G.
+===Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:35:44 2009''
+<!--

OCA at 10:35, 11 February 2009

2009-02-11T10:35:44Z

← Older revision		Revision as of 10:35, 11 February 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3fvm is ON HOLD		The entry 3fvm is ON HOLD until Paper Publication

	Authors: Peng, H., Zhang, Q.J., Gao, F., Liu, Y.W., Gao, F.G.		Authors: Peng, H., Zhang, Q.J., Gao, F., Liu, Y.W., Gao, F.G.
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	Description: Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++		Description: Crystal structure of Steptococcus suis mannonate dehydratase with metal Mn++

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:26:18 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 11 12:35:44 2009''