3gbe - Revision history

OCA at 15:38, 1 November 2023

2023-11-01T15:38:06Z

← Older revision		Revision as of 15:38, 1 November 2023
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	<StructureSection load='3gbe' size='340' side='right'caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gbe' size='340' side='right'caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3GBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_plymuthica Serratia plymuthica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=EDO:1,2~~-~~ETHANEDIOL'>EDO</scene>~~, ~~<scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:~~1~~-DEOXYNOJIRIMYCIN'>NOJ</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[3gbd\|3gbd]]~~<~~/td~~></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11]~~ </~~span~~></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [https://pdbe.org/3gbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [https://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [~~http~~://pdbe.org/3gbe PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/D0VX20_SERPL D0VX20_SERPL]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</div>		</div>
	<div class="pdbe-citations 3gbe" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3gbe" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Trehalulose synthase\|Trehalulose synthase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Isomaltulose synthase]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Aghajari, N]]		[[Category: Serratia plymuthica]]
	[[Category: Haser, R]]		[[Category: Aghajari N]]
	[[Category: Ravaud, S]]		[[Category: Haser R]]
	[[Category: Robert, X]]		[[Category: Ravaud S]]
	~~[[Category: Deoxynojirimycin complex]]~~		[[Category: Robert X]]
	~~[[Category: Glycoside hydrolase]]~~
	~~[[Category: Isomerase]]~~
	~~[[Category: Protaminobacter rubrum]]~~
	~~[[Category: Sucrose isomerase~~]]

OCA at 10:38, 9 September 2020

2020-09-09T10:38:06Z

← Older revision		Revision as of 10:38, 9 September 2020
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	==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==		==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==
	<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gbe' size='340' side='right'caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3GBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	</StructureSection>		</StructureSection>
	[[Category: Isomaltulose synthase]]		[[Category: Isomaltulose synthase]]
			[[Category: Large Structures]]
	[[Category: Aghajari, N]]		[[Category: Aghajari, N]]
	[[Category: Haser, R]]		[[Category: Haser, R]]

OCA at 05:39, 7 December 2018

2018-12-07T05:39:43Z

← Older revision		Revision as of 05:39, 7 December 2018
Line 1:		Line 1:

	==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==		==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==
	<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/'protaminobacter_rubrum' 'protaminobacter rubrum']~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">smuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126825 'Protaminobacter rubrum'])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3gbe ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/3gbe_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/3gbe_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Protaminobacter rubrum]]~~
	[[Category: Isomaltulose synthase]]		[[Category: Isomaltulose synthase]]
	[[Category: Aghajari, N]]		[[Category: Aghajari, N]]
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	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
			[[Category: Protaminobacter rubrum]]
	[[Category: Sucrose isomerase]]		[[Category: Sucrose isomerase]]

OCA at 15:05, 7 February 2016

2016-02-07T15:05:53Z

← Older revision		Revision as of 15:05, 7 February 2016
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	<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Protaminobacter_rubrum Protaminobacter~~ rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>		<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/'protaminobacter_rubrum' 'protaminobacter rubrum']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">smuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126825 Protaminobacter rubrum])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">smuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126825 'Protaminobacter rubrum'])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://pdbe.org/3gbe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gbe ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3gbe" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Protaminobacter rubrum]]
	[[Category: Isomaltulose synthase]]		[[Category: Isomaltulose synthase]]
	~~[[Category: Protaminobacter rubrum]]~~
	[[Category: Aghajari, N]]		[[Category: Aghajari, N]]
	[[Category: Haser, R]]		[[Category: Haser, R]]

OCA at 10:04, 3 December 2014

2014-12-03T10:04:40Z

← Older revision		Revision as of 10:04, 3 December 2014
Line 1:		Line 1:
	[[Image:~~3gbe~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin==
			<StructureSection load='3gbe' size='340' side='right' caption='[[3gbe]], [[Resolution\|resolution]] 1.70Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3gbe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Protaminobacter_rubrum Protaminobacter rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3GBE FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NOJ:1-DEOXYNOJIRIMYCIN'>NOJ</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3gbd\|3gbd]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">smuA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=126825 Protaminobacter rubrum])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isomaltulose_synthase Isomaltulose synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.11 5.4.99.11] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3gbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gbe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3gbe RCSB], [http://www.ebi.ac.uk/pdbsum/3gbe PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/3gbe_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			The healthy sweetener isomaltulose is industrially produced from the conversion of sucrose by the sucrose isomerase SmuA from Protaminobacter rubrum. Crystal structures of SmuA in native and deoxynojirimycin complexed forms completed with modeling studies unravel the characteristics of the isomaltulose synthases catalytic pocket and their substrate binding mode. Comparison with the trehalulose synthase MutB highlights the role of Arg(298) and Arg(306) active site residues and surface charges in controlling product specificity of sucrose isomerases (isomaltulose versus trehalulose). The results provide a rationale for the specific design of optimized enzymes.

	~~{{STRUCTURE_3gbe\| PDB=3gbe \| SCENE= }}~~		Structural determinants of product specificity of sucrose isomerases.,Ravaud S, Robert X, Watzlawick H, Haser R, Mattes R, Aghajari N FEBS Lett. 2009 Jun 18;583(12):1964-8. Epub 2009 May 8. PMID:19427862<ref>PMID:19427862</ref>

	~~===Crystal structure~~ of the ~~isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_19427862}}~~		== References ==
			<references/>
	~~==About this Structure==~~		__TOC__
	~~[[3gbe]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Protaminobacter_rubrum Protaminobacter rubrum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA].~~		</StructureSection>

	==~~Reference~~==
	<~~ref group="xtra">PMID:019427862<~~/~~ref~~><~~references group="xtra"~~/>
	[[Category: Isomaltulose synthase]]		[[Category: Isomaltulose synthase]]
	[[Category: Protaminobacter rubrum]]		[[Category: Protaminobacter rubrum]]
	[[Category: Aghajari, N.]]		[[Category: Aghajari, N]]
	[[Category: Haser, R.]]		[[Category: Haser, R]]
	[[Category: Ravaud, S.]]		[[Category: Ravaud, S]]
	[[Category: Robert, X.]]		[[Category: Robert, X]]
	[[Category: Deoxynojirimycin complex]]		[[Category: Deoxynojirimycin complex]]
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
	[[Category: Isomerase]]		[[Category: Isomerase]]
	~~[[Category: Protaminobacter rubrum]]~~
	[[Category: Sucrose isomerase]]		[[Category: Sucrose isomerase]]

OCA: Protected "3gbe" [edit=sysop:move=sysop]

2013-02-20T14:11:27Z

Protected "3gbe" [edit=sysop:move=sysop]

← Older revision	Revision as of 14:11, 20 February 2013
(No difference)

OCA at 14:11, 20 February 2013

2013-02-20T14:11:23Z

← Older revision		Revision as of 14:11, 20 February 2013
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	~~{{Seed}}~~
	[[Image:3gbe.png\|left\|200px]]		[[Image:3gbe.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3gbe", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3gbe\| PDB=3gbe \| SCENE= }}		{{STRUCTURE_3gbe\| PDB=3gbe \| SCENE= }}

	===Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin===		===Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_19427862}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 19427862 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_19427862}}		{{ABSTRACT_PUBMED_19427862}}

	==About this Structure==		==About this Structure==
	~~3GBE~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Protaminobacter_rubrum Protaminobacter rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA].		[[3gbe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Protaminobacter_rubrum Protaminobacter rubrum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GBE OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~19427862~~</ref><references group="xtra"/>		<ref group="xtra">PMID:019427862</ref><references group="xtra"/>
	[[Category: Isomaltulose synthase]]		[[Category: Isomaltulose synthase]]
	[[Category: Protaminobacter rubrum]]		[[Category: Protaminobacter rubrum]]
Line 32:		Line 20:
	[[Category: Deoxynojirimycin complex]]		[[Category: Deoxynojirimycin complex]]
	[[Category: Glycoside hydrolase]]		[[Category: Glycoside hydrolase]]
			[[Category: Isomerase]]
	[[Category: Protaminobacter rubrum]]		[[Category: Protaminobacter rubrum]]
	[[Category: Sucrose isomerase]]		[[Category: Sucrose isomerase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 09:54:22 2009''~~

OCA at 06:54, 1 July 2009

2009-07-01T06:54:24Z

← Older revision		Revision as of 06:54, 1 July 2009
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	{{Seed}}		{{Seed}}
	[[Image:3gbe.~~jpg~~\|left\|200px]]		[[Image:3gbe.png\|left\|200px]]

	<!--		<!--
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	[[Category: Sucrose isomerase]]		[[Category: Sucrose isomerase]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 27 15~~:11:33 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 1 09:54:22 2009''

OCA at 12:11, 27 May 2009

2009-05-27T12:11:34Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3gbe is ON HOLD  until Paper Publication
+<!--
-Authors: Ravaud, S., Robert, X., Watzlawick, H., Haser, R., Mattes, R., Aghajari, N.
+===Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:24:15 2009''
+<!--

OCA at 08:24, 22 March 2009

2009-03-22T08:24:15Z

← Older revision		Revision as of 08:24, 22 March 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3gbe is ON HOLD		The entry 3gbe is ON HOLD until Paper Publication

	Authors: Ravaud, S., Robert, X., Watzlawick, H., Haser, R., Mattes, R., Aghajari, N.		Authors: Ravaud, S., Robert, X., Watzlawick, H., Haser, R., Mattes, R., Aghajari, N.

	Description: Crystal structure of ~~sucrose isomerase~~ SmuA from Protaminobacter rubrum in complex with deoxynojirimycin ~~inhibitor~~		Description: Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed~~ Mar ~~11 11~~:11:04 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:24:15 2009''