3hlw - Revision history

OCA at 15:50, 1 November 2023

2023-11-01T15:50:35Z

← Older revision		Revision as of 15:50, 1 November 2023
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	<StructureSection load='3hlw' size='340' side='right'caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3hlw' size='340' side='right'caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene>~~</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [https://pdbe.org/3hlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [https://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [https://pdbe.org/3hlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [https://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/Q9L5C8_ECOLX Q9L5C8_ECOLX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bonnet, R]]		[[Category: Bonnet R]]
	[[Category: Delmas, J]]		[[Category: Delmas J]]
	[[Category: Dubois, D]]		[[Category: Dubois D]]
	[[Category: Leyssne, D]]		[[Category: Leyssne D]]
	[[Category: Robin, F]]		[[Category: Robin F]]
	[[Category: Vazeille, E]]		[[Category: Vazeille E]]
	~~[[Category: Antibiotic resistance]]~~
	~~[[Category: Beta-lactam]]~~
	~~[[Category: Beta-lactamase]]~~
	~~[[Category: Cefotaxime]]~~
	~~[[Category: Cephalosporin]]~~
	~~[[Category: Complex]]~~
	~~[[Category: Ctx-m]]~~
	~~[[Category: Ctx-m-9]]~~
	~~[[Category: Esbl]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Michaeli~~]]

OCA at 07:44, 10 November 2021

2021-11-10T07:44:39Z

← Older revision		Revision as of 07:44, 10 November 2021
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	==CTX-M-9 S70G in complex with cefotaxime==		==CTX-M-9 S70G in complex with cefotaxime==
	<StructureSection load='3hlw' size='340' side='right' caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3hlw' size='340' side='right'caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3HLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [~~http~~://pdbe.org/3hlw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [https://pdbe.org/3hlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [https://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	==See Also==		==See Also==
	*[[Beta-lactamase\|Beta-lactamase]]		*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
			[[Category: Large Structures]]
	[[Category: Bonnet, R]]		[[Category: Bonnet, R]]
	[[Category: Delmas, J]]		[[Category: Delmas, J]]

OCA at 07:35, 12 December 2018

2018-12-12T07:35:46Z

← Older revision		Revision as of 07:35, 12 December 2018
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/3hlw_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/3hlw_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 15:41, 5 August 2016

2016-08-05T15:41:34Z

← Older revision		Revision as of 15:41, 5 August 2016
Line 1:		Line 1:

	==CTX-M-9 S70G in complex with cefotaxime==		==CTX-M-9 S70G in complex with cefotaxime==
	<StructureSection load='3hlw' size='340' side='right' caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='3hlw' size='340' side='right' caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HLW FirstGlance]. <br>		<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [http://www.ebi.ac.uk/pdbsum/3hlw PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [http://pdbe.org/3hlw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [http://www.ebi.ac.uk/pdbsum/3hlw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hlw ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hlw ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3hlw" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Escherichia~~ coli]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Bonnet, R]]		[[Category: Bonnet, R]]
	[[Category: Delmas, J]]		[[Category: Delmas, J]]

OCA at 16:35, 18 December 2014

2014-12-18T16:35:50Z

← Older revision		Revision as of 16:35, 18 December 2014
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	~~{{STRUCTURE_3hlw~~\| ~~PDB~~=3hlw \| ~~SCENE~~= }}		==CTX-M-9 S70G in complex with cefotaxime==
	===~~CTX~~-M-9 ~~S70G in complex with cefotaxime~~===		<StructureSection load='3hlw' size='340' side='right' caption='[[3hlw]], [[Resolution\|resolution]] 1.50Å' scene=''>
	~~{{ABSTRACT_PUBMED_20452359}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HLW FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE3:(6R,7R)-3-(ACETYLOXYMETHYL)-7-[[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-METHOXYIMINO-ETHANOYL]AMINO]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC+ACID'>CE3</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaCTX-M-9, blaCTX-M-9a, blaCTX-M-9b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3hlw RCSB], [http://www.ebi.ac.uk/pdbsum/3hlw PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/3hlw_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			beta-Lactamase-mediated resistance to beta-lactam antibiotics poses a major threat to our antibiotic armamentarium. Among beta-lactamases, a significant threat comes from enzymes that hydrolyze extended-spectrum cephalosporins such as cefotaxime. Among the enzymes that exhibit this phenotype, the CTX-M family is found worldwide. These enzymes have a small active site, which makes it difficult to explain how they hydrolyze the bulky extended-spectrum cephalosporins into the binding site. We investigated noncovalent substrate recognition and product release in CTX-M enzymes using steered molecular dynamics simulation and X-ray diffraction. An arginine residue located far from the binding site favors the capture and tracking of substrates during entrance into the catalytic pocket. We show that the accommodation of extended-spectrum cephalosporins by CTX-M enzymes induced subtle changes in the active site and established a high density of electrostatic interactions. Interestingly, the product of the catalytic reaction initiates its own release because of steric hindrances and electrostatic repulsions. This suggests that there exists a general mechanism for product release for all members of the beta-lactamase family and probably for most carboxypeptidases.

	~~==About this Structure==~~		Structural insights into substrate recognition and product expulsion in CTX-M enzymes.,Delmas J, Leyssene D, Dubois D, Birck C, Vazeille E, Robin F, Bonnet R J Mol Biol. 2010 Jul 2;400(1):108-20. Epub 2010 May 7. PMID:20452359<ref>PMID:20452359</ref>
	~~[[3hlw]] is a~~ 2 ~~chain structure with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.~~il/oca-bin~~/~~ocashort?id=3HLW OCA].~~
			From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>

	==See Also==		==See Also==
	*[[Beta-lactamase\|Beta-lactamase]]		*[[Beta-lactamase\|Beta-lactamase]]
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:020452359</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bonnet, R.]]		[[Category: Bonnet, R]]
	[[Category: Delmas, J.]]		[[Category: Delmas, J]]
	[[Category: Dubois, D.]]		[[Category: Dubois, D]]
	[[Category: Leyssne, D.]]		[[Category: Leyssne, D]]
	[[Category: Robin, F.]]		[[Category: Robin, F]]
	[[Category: Vazeille, E.]]		[[Category: Vazeille, E]]
	[[Category: Antibiotic resistance]]		[[Category: Antibiotic resistance]]
	[[Category: Beta-lactam]]		[[Category: Beta-lactam]]

OCA at 05:33, 6 November 2013

2013-11-06T05:33:53Z

← Older revision		Revision as of 05:33, 6 November 2013
Line 5:		Line 5:
	==About this Structure==		==About this Structure==
	[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].		[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].

			==See Also==
			*[[Beta-lactamase\|Beta-lactamase]]

	==Reference==		==Reference==

OCA at 21:07, 19 June 2013

2013-06-19T21:07:48Z

← Older revision		Revision as of 21:07, 19 June 2013
Line 1:		Line 1:
	~~[[Image:3hlw.png\|left\|200px]]~~

	{{STRUCTURE_3hlw\| PDB=3hlw \| SCENE= }}		{{STRUCTURE_3hlw\| PDB=3hlw \| SCENE= }}

	===CTX-M-9 S70G in complex with cefotaxime===		===CTX-M-9 S70G in complex with cefotaxime===

	{{ABSTRACT_PUBMED_20452359}}		{{ABSTRACT_PUBMED_20452359}}

	==About this Structure==		==About this Structure==
	[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].		[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].

	~~==See Also==~~
	*[[Beta-lactamase\|Beta-lactamase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:020452359</ref><references group="xtra"/>		<ref group="xtra">PMID:020452359</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bonnet, R.]]		[[Category: Bonnet, R.]]

OCA at 12:16, 20 October 2012

2012-10-20T12:16:35Z

← Older revision		Revision as of 12:16, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[3hlw]] is a 2 chain structure ~~of [[Beta-lactamase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].		[[3hlw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].

	==See Also==		==See Also==

OCA: Protected "3hlw" [edit=sysop:move=sysop]

2012-07-26T08:11:02Z

Protected "3hlw" [edit=sysop:move=sysop]

← Older revision	Revision as of 08:11, 26 July 2012
(No difference)

OCA at 08:11, 26 July 2012

2012-07-26T08:11:00Z

← Older revision		Revision as of 08:11, 26 July 2012
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	~~{{Seed}}~~
	[[Image:3hlw.png\|left\|200px]]		[[Image:3hlw.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3hlw", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3hlw\| PDB=3hlw \| SCENE= }}		{{STRUCTURE_3hlw\| PDB=3hlw \| SCENE= }}

	===CTX-M-9 S70G in complex with cefotaxime===		===CTX-M-9 S70G in complex with cefotaxime===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_20452359}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 20452359 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_20452359}}		{{ABSTRACT_PUBMED_20452359}}

	==About this Structure==		==About this Structure==
	~~3HLW~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].		[[3hlw]] is a 2 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HLW OCA].

			==See Also==
			*[[Beta-lactamase\|Beta-lactamase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20452359~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020452359</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Bonnet, R.]]		[[Category: Bonnet, R.]]
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	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Michaeli]]		[[Category: Michaeli]]
	~~[[Category: Plasmid]]~~

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 07:58:09 2010''~~