3imo - Revision history

OCA at 08:28, 20 March 2024

2024-03-20T08:28:05Z

@@ Line 10: / Line 10: @@
 == Function ==
 [https://www.uniprot.org/uniprot/C7U313_VIBCL C7U313_VIBCL]
 __TOC__
 </StructureSection>

OCA at 14:10, 24 January 2024

2024-01-24T14:10:58Z

← Older revision		Revision as of 14:10, 24 January 2024
Line 3:		Line 3:
	<StructureSection load='3imo' size='340' side='right'caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3imo' size='340' side='right'caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Vibrio_cholerae_o139~~ Vibrio cholerae ~~o139~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IMO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O139 Vibrio cholerae O139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IMO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
			<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [https://pdbe.org/3imo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [https://www.ebi.ac.uk/pdbsum/3imo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3imo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [https://pdbe.org/3imo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [https://www.ebi.ac.uk/pdbsum/3imo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3imo ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/C7U313_VIBCL C7U313_VIBCL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Vibrio cholerae ~~o139~~]]		[[Category: Vibrio cholerae O139]]
	[[Category: Boucher, Y]]		[[Category: Boucher Y]]
	[[Category: Curmi~~, P M.G~~]]		[[Category: Curmi PMG]]
	[[Category: Deshpande~~, C N~~]]		[[Category: Deshpande CN]]
	[[Category: Harrop~~, S J~~]]		[[Category: Harrop SJ]]
	[[Category: Mabbutt~~, B C~~]]		[[Category: Mabbutt BC]]
	[[Category: Stokes~~, H W~~]]		[[Category: Stokes HW]]
	[[Category: Sureshan, V]]		[[Category: Sureshan V]]
	~~[[Category: Argentinean o139 strain]]~~
	~~[[Category: Integron protein]]~~
	~~[[Category: Novel]]~~
	~~[[Category: Unknown function]]~~
	~~[[Category: Vibrio cholerae~~]]

OCA at 03:36, 21 April 2022

2022-04-21T03:36:23Z

← Older revision		Revision as of 03:36, 21 April 2022
Line 3:		Line 3:
	<StructureSection load='3imo' size='340' side='right'caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3imo' size='340' side='right'caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3IMO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IMO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [~~http~~://pdbe.org/3imo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3imo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3imo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [https://pdbe.org/3imo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [https://www.ebi.ac.uk/pdbsum/3imo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3imo ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:58, 7 August 2019

2019-08-07T06:58:59Z

← Older revision		Revision as of 06:58, 7 August 2019
Line 1:		Line 1:

	==Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14==		==Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14==
	<StructureSection load='3imo' size='340' side='right' caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3imo' size='340' side='right'caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IMO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IMO FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Large Structures]]
	[[Category: Vibrio cholerae o139]]		[[Category: Vibrio cholerae o139]]
	[[Category: Boucher, Y]]		[[Category: Boucher, Y]]

OCA at 19:32, 4 August 2016

2016-08-04T19:32:59Z

← Older revision		Revision as of 19:32, 4 August 2016
Line 1:		Line 1:

	==Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14==		==Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14==
	<StructureSection load='3imo' size='340' side='right' caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3imo' size='340' side='right' caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IMO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IMO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [http://www.ebi.ac.uk/pdbsum/3imo PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [http://pdbe.org/3imo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [http://www.ebi.ac.uk/pdbsum/3imo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3imo ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3imo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:14, 8 December 2014

2014-12-08T09:14:28Z

← Older revision		Revision as of 09:14, 8 December 2014
Line 1:		Line 1:
	[[~~Image~~:3imo.~~png\|left\|200px~~]]		==Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14==
			<StructureSection load='3imo' size='340' side='right' caption='[[3imo]], [[Resolution\|resolution]] 1.80Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IMO FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3imo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3imo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3imo RCSB], [http://www.ebi.ac.uk/pdbsum/3imo PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Mobile gene cassettes captured within integron arrays encompass a vast and diverse pool of genetic novelty. In most cases, functional annotation of gene cassettes directly recovered by cassette-PCR is obscured by their characteristically high sequence novelty. This inhibits identification of those specific functions or biological features that might constitute preferential factors for lateral gene transfer via the integron system. A structural genomics approach incorporating x-ray crystallography has been utilised on a selection of cassettes to investigate evolutionary relationships hidden at the sequence level. Gene cassettes were accessed from marine sediments (pristine and contaminated sites), as well as a range of Vibrio spp. We present six crystal structures, a remarkably high proportion of our survey of soluble proteins, which were found to possess novel folds. These entirely new structures are diverse, encompassing all-alpha, alpha+beta and alpha/beta fold classes, and many contain clear binding pocket features for small molecule substrates. The new structures emphasise the large repertoire of protein families encoded within the integron cassette metagenome and which remain to be characterised. Oligomeric association is a notable recurring property common to these new integron-derived proteins. In some cases, the protein-protein contact sites utilised in homomeric assembly could instead form suitable contact points for heterogeneous regulator/activator proteins or domains. Such functional features are ideal for a flexible molecular componentry needed to ensure responsive and adaptive bacterial functions.

	~~{{STRUCTURE_3imo\| PDB=3imo \| SCENE= }}~~		Integron gene cassettes: a repository of novel protein folds with distinct interaction sites.,Sureshan V, Deshpande CN, Boucher Y, Koenig JE, Stokes HW, Harrop SJ, Curmi PM, Mabbutt BC PLoS One. 2013;8(1):e52934. doi: 10.1371/journal.pone.0052934. Epub 2013 Jan 18. PMID:23349695<ref>PMID:23349695</ref>

	~~===Structure from~~ the ~~mobile metagenome~~ of ~~Vibrio cholerae~~. ~~Integron cassette protein VCH_CASS14===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_23349695}}~~		== References ==
			<references/>
	==~~About this Structure~~==		__TOC__
	~~[[3imo]] is a 4 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA].~~		</StructureSection>
	[[Category: Vibrio cholerae o139]]		[[Category: Vibrio cholerae o139]]
	[[Category: Boucher, Y.]]		[[Category: Boucher, Y]]
	[[Category: Curmi, P M.G.]]		[[Category: Curmi, P M.G]]
	[[Category: Deshpande, C N.]]		[[Category: Deshpande, C N]]
	[[Category: Harrop, S J.]]		[[Category: Harrop, S J]]
	[[Category: Mabbutt, B C.]]		[[Category: Mabbutt, B C]]
	[[Category: Stokes, H W.]]		[[Category: Stokes, H W]]
	[[Category: Sureshan, V.]]		[[Category: Sureshan, V]]
	[[Category: Argentinean o139 strain]]		[[Category: Argentinean o139 strain]]
	[[Category: Integron protein]]		[[Category: Integron protein]]

OCA: Protected "3imo" [edit=sysop:move=sysop]

2013-02-06T12:49:20Z

Protected "3imo" [edit=sysop:move=sysop]

← Older revision	Revision as of 12:49, 6 February 2013
(No difference)

OCA at 12:49, 6 February 2013

2013-02-06T12:49:17Z

← Older revision		Revision as of 12:49, 6 February 2013
Line 1:		Line 1:
	~~{{Seed}}~~
	[[Image:3imo.png\|left\|200px]]		[[Image:3imo.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3imo", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3imo\| PDB=3imo \| SCENE= }}		{{STRUCTURE_3imo\| PDB=3imo \| SCENE= }}

	===Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14===		===Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14===

			{{ABSTRACT_PUBMED_23349695}}

	==About this Structure==		==About this Structure==
	~~3IMO~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA].		[[3imo]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o139 Vibrio cholerae o139]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMO OCA].
	[[Category: Vibrio cholerae o139]]		[[Category: Vibrio cholerae o139]]
	[[Category: Boucher, Y.]]		[[Category: Boucher, Y.]]
Line 28:		Line 22:
	[[Category: Unknown function]]		[[Category: Unknown function]]
	[[Category: Vibrio cholerae]]		[[Category: Vibrio cholerae]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:26:44 2009''~~

OCA at 14:26, 21 September 2009

2009-09-21T14:26:45Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3imo is ON HOLD
+<!--
-Authors: Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C.
+===Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:37:39 2009''
+==About this Structure==

OCA: New page: '''Unreleased structure''' The entry 3imo is ON HOLD Authors: Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C. Description: Structur...

2009-08-19T09:37:40Z

New page: '''Unreleased structure''' The entry 3imo is ON HOLD Authors: Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C. Description: Structur...

New page

'''Unreleased structure'''

The entry 3imo is ON HOLD

Authors: Deshpande, C.N., Sureshan, V., Harrop, S.J., Boucher, Y., Stokes, H.W., Curmi, P.M.G., Mabbutt, B.C.

Description: Structure from the mobile metagenome of Vibrio cholerae. Integron cassette protein VCH_CASS14

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:37:39 2009''