3jso - Revision history

OCA at 10:13, 21 February 2024

2024-02-21T10:13:12Z

← Older revision		Revision as of 10:13, 21 February 2024
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	<StructureSection load='3jso' size='340' side='right'caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='3jso' size='340' side='right'caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JSO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JSO FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3jsp\|3jsp]]</div></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.29Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=83333 ECOLI])</td></tr>~~
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [https://pdbe.org/3jso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [https://www.ebi.ac.uk/pdbsum/3jso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jso ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [https://pdbe.org/3jso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [https://www.ebi.ac.uk/pdbsum/3jso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jso ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>		[https://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jso ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jso ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~<div style="background-color:#fffaf0;">~~
	~~== Publication Abstract from PubMed ==~~
	The eubacterial SOS system is a paradigm of cellular DNA damage and repair, and its activation can contribute to antibiotic resistance. Under normal conditions, LexA represses the transcription of many DNA repair proteins by binding to SOS 'boxes' in their operators. Under genotoxic stress, accumulating complexes of RecA, ATP and single-stranded DNA (ssDNA) activate LexA for autocleavage. To address how LexA recognizes its binding sites, we determined three crystal structures of Escherichia coli LexA in complex with SOS boxes. Here we report the structure of these LexA-DNA complexes. The DNA-binding domains of the LexA dimer interact with the DNA in the classical fashion of a winged helix-turn-helix motif. However, the wings of these two DNA-binding domains bind to the same minor groove of the DNA. These wing-wing contacts may explain why the spacing between the two half-sites of E. coli SOS boxes is invariant.

	~~Structure of the LexA-DNA complex and implications for SOS box measurement.,Zhang AP, Pigli YZ, Rice PA Nature. 2010 Aug 12;466(7308):883-6. PMID:20703307<ref>PMID:20703307</ref>~~

	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~
	~~</div>~~
	~~<div class="pdbe-citations 3jso" style="background-color:#fffaf0;"></div>~~
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Ecoli~~]]		[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	~~[[Category: Repressor lexA]]~~		[[Category: Pigli YZ]]
	[[Category: Pigli~~, Y Z~~]]		[[Category: Rice PA]]
	[[Category: Rice~~, P A~~]]		[[Category: Zhang APP]]
	[[Category: Zhang~~, A P.P]]~~
	~~[[Category: Autocatalytic cleavage]]~~
	~~[[Category: Dna damage]]~~
	~~[[Category: Dna repair]]~~
	~~[[Category: Dna replication]]~~
	~~[[Category: Dna-binding]]~~
	~~[[Category: Double helix]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Hydrolase-dna complex]]~~
	~~[[Category: Lexa]]~~
	~~[[Category: Protein-dna complex]]~~
	~~[[Category: Repressor]]~~
	~~[[Category: Sos response]]~~
	~~[[Category: Sos system]]~~
	~~[[Category: Transcription]]~~
	~~[[Category: Transcription regulation]]~~
	~~[[Category: Winged helix-turn-helix~~]]

OCA at 12:17, 13 October 2021

2021-10-13T12:17:20Z

← Older revision		Revision as of 12:17, 13 October 2021
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	==Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex==		==Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex==
	<StructureSection load='3jso' size='340' side='right' caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='3jso' size='340' side='right'caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3JSO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JSO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3jsp\|3jsp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3jsp\|3jsp]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [~~http~~://pdbe.org/3jso PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3jso PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3jso ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [https://pdbe.org/3jso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [https://www.ebi.ac.uk/pdbsum/3jso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jso ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>		[[https://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/3jso_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/js/3jso_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
			[[Category: Large Structures]]
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	[[Category: Pigli, Y Z]]		[[Category: Pigli, Y Z]]

OCA at 04:45, 5 August 2016

2016-08-05T04:45:59Z

← Older revision		Revision as of 04:45, 5 August 2016
Line 1:		Line 1:

	==Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex==		==Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex==
	<StructureSection load='3jso' size='340' side='right' caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='3jso' size='340' side='right' caption='[[3jso]], [[Resolution\|resolution]] 2.29Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [http://www.ebi.ac.uk/pdbsum/3jso PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [http://pdbe.org/3jso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [http://www.ebi.ac.uk/pdbsum/3jso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3jso ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jso ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3jso" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:53, 25 December 2014

2014-12-25T15:53:33Z

← Older revision		Revision as of 15:53, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JSO FirstGlance]. <br>		<table><tr><td colspan='2'>[[3jso]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3JSO FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3jsp\|3jsp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3jsp\|3jsp]]</td></tr>
	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, exrA, spr, tsl, umuA, b4043, JW4003 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [http://www.ebi.ac.uk/pdbsum/3jso PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3jso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jso OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3jso RCSB], [http://www.ebi.ac.uk/pdbsum/3jso PDBsum]</span></td></tr>
	<table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/LEXA_ECOLI LEXA_ECOLI]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.<ref>PMID:7027255</ref> <ref>PMID:7027256</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 24:		Line 26:
	Structure of the LexA-DNA complex and implications for SOS box measurement.,Zhang AP, Pigli YZ, Rice PA Nature. 2010 Aug 12;466(7308):883-6. PMID:20703307<ref>PMID:20703307</ref>		Structure of the LexA-DNA complex and implications for SOS box measurement.,Zhang AP, Pigli YZ, Rice PA Nature. 2010 Aug 12;466(7308):883-6. PMID:20703307<ref>PMID:20703307</ref>

	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 32:		Line 34:
	[[Category: Ecoli]]		[[Category: Ecoli]]
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	[[Category: Pigli, Y Z.]]		[[Category: Pigli, Y Z]]
	[[Category: Rice, P A.]]		[[Category: Rice, P A]]
	[[Category: Zhang, A P.P.]]		[[Category: Zhang, A P.P]]
	[[Category: Autocatalytic cleavage]]		[[Category: Autocatalytic cleavage]]
	[[Category: Dna damage]]		[[Category: Dna damage]]

OCA at 09:42, 21 May 2014

2014-05-21T09:42:47Z

@@ Line 1: / Line 1: @@
-[[Image:3jso.png|left|200px]]
+==Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex==
-<!--
+Structure of the LexA-DNA complex and implications for SOS box measurement.,Zhang AP, Pigli YZ, Rice PA Nature. 2010 Aug 12;466(7308):883-6. PMID:20703307<ref>PMID:20703307</ref>
-===Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex===
+From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
+</div>
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_20703307}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 20703307 is the PubMed ID number.
+</StructureSection>
--->
+[[Category: Ecoli]]
 [[Category: Repressor lexA]]
 [[Category: Pigli, Y Z.]]

OCA: Protected "3jso" [edit=sysop:move=sysop]

2012-03-21T06:22:43Z

Protected "3jso" [edit=sysop:move=sysop]

← Older revision	Revision as of 06:22, 21 March 2012
(No difference)

OCA at 06:22, 21 March 2012

2012-03-21T06:22:41Z

← Older revision		Revision as of 06:22, 21 March 2012
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	~~{{Seed}}~~		[[Image:3jso.png\|left\|200px]]
	[[Image:3jso.~~jpg~~\|left\|200px]]

	<!--		<!--
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	===Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex===		===Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_20703307}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 20703307 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20703307}}

	==About this Structure==		==About this Structure==
	~~3JSO~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA].		[[3jso]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSO OCA].

			==Reference==
			<ref group="xtra">PMID:020703307</ref><references group="xtra"/>
	[[Category: Escherichia coli k-12]]		[[Category: Escherichia coli k-12]]
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
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	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
	[[Category: Winged helix-turn-helix]]		[[Category: Winged helix-turn-helix]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:41:36 2010''~~

OCA at 07:34, 18 August 2010

2010-08-18T07:34:04Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3jso is ON HOLD  until Paper Publication
+<!--
-Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A.
+===Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:48:37 2009''
+==About this Structure==

OCA at 16:48, 18 November 2009

2009-11-18T16:48:38Z

← Older revision		Revision as of 16:48, 18 November 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3jso is ON HOLD		The entry 3jso is ON HOLD until Paper Publication

	Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A.		Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A.
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	Description: Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex		Description: Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 16 08~~:46:11 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:48:37 2009''

OCA: New page: '''Unreleased structure''' The entry 3jso is ON HOLD Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A. Description: Classic Protein With a New Twist: crystal structure of a LexA represso...

2009-09-16T05:46:12Z

New page: '''Unreleased structure''' The entry 3jso is ON HOLD Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A. Description: Classic Protein With a New Twist: crystal structure of a LexA represso...

New page

'''Unreleased structure'''

The entry 3jso is ON HOLD

Authors: Zhang, A.P.P., Pigli, Y.Z., Rice, P.A.

Description: Classic Protein With a New Twist: crystal structure of a LexA repressor DNA complex

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:46:11 2009''