3k2z - Revision history

OCA at 10:14, 21 February 2024

2024-02-21T10:14:54Z

← Older revision		Revision as of 10:14, 21 February 2024
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	<StructureSection load='3k2z' size='340' side='right'caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>		<StructureSection load='3k2z' size='340' side='right'caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.37Å</td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>lexA, TM_1082 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~2336 ATCC 43589])</td~~><~~/tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [https://pdbe.org/3k2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [https://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [https://pdbe.org/3k2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [https://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[https://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).		[https://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	~~[[Category: Atcc 43589]]~~
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: ~~Repressor lexA~~]]		[[Category: Thermotoga maritima]]
	[[Category: Rice~~, P A~~]]		[[Category: Rice PA]]
	[[Category: Zhang~~, A P.P]]~~		[[Category: Zhang APP]]
	~~[[Category: Autocatalytic cleavage]]~~
	~~[[Category: Dna damage]]~~
	~~[[Category: Dna repair]]~~
	~~[[Category: Dna replication]]~~
	~~[[Category: Dna-binding]]~~
	~~[[Category: Hydrolase]]~~
	~~[[Category: Lexa]]~~
	~~[[Category: Repressor]]~~
	~~[[Category: Sos response]]~~
	~~[[Category: Sos system]]~~
	~~[[Category: Transcription]]~~
	~~[[Category: Transcription regulation]]~~
	~~[[Category: Winged helix-turn-helix~~]]

OCA at 12:20, 13 October 2021

2021-10-13T12:20:38Z

← Older revision		Revision as of 12:20, 13 October 2021
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	==Crystal structure of a LexA protein from Thermotoga maritima==		==Crystal structure of a LexA protein from Thermotoga maritima==
	<StructureSection load='3k2z' size='340' side='right' caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>		<StructureSection load='3k2z' size='340' side='right'caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, TM_1082 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, TM_1082 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [~~http~~://pdbe.org/3k2z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [https://pdbe.org/3k2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [https://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[~~http~~://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).		[[https://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/3k2z_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/3k2z_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
			[[Category: Large Structures]]
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	[[Category: Rice, P A]]		[[Category: Rice, P A]]

OCA at 11:44, 4 August 2016

2016-08-04T11:44:29Z

← Older revision		Revision as of 11:44, 4 August 2016
Line 1:		Line 1:

	==Crystal structure of a LexA protein from Thermotoga maritima==		==Crystal structure of a LexA protein from Thermotoga maritima==
	<StructureSection load='3k2z' size='340' side='right' caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>		<StructureSection load='3k2z' size='340' side='right' caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, TM_1082 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ~~Thermotoga maritima~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, TM_1082 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://pdbe.org/3k2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k2z ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Atcc 43589]]
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	~~[[Category: Thermotoga maritima]]~~
	[[Category: Rice, P A]]		[[Category: Rice, P A]]
	[[Category: Zhang, A P.P]]		[[Category: Zhang, A P.P]]

OCA at 08:58, 25 December 2014

2014-12-25T08:58:35Z

← Older revision		Revision as of 08:58, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:52, 18 December 2014

2014-12-18T17:52:11Z

← Older revision		Revision as of 17:52, 18 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_3k2z\| PDB=3k2z \| SCENE= }}~~		==Crystal structure of a LexA protein from Thermotoga maritima==
	===Crystal structure of a LexA protein from Thermotoga maritima===		<StructureSection load='3k2z' size='340' side='right' caption='[[3k2z]], [[Resolution\|resolution]] 1.37Å' scene=''>
			== Structural highlights ==
	==~~Function~~==		<table><tr><td colspan='2'>[[3k2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K2Z FirstGlance]. <br>
	[[~~http://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA~~]] ~~Represses a number of genes involved in the response to DNA damage (SOS response)~~, including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lexA, TM_1082 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr>
	==~~About this Structure~~==		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Repressor_lexA Repressor lexA], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.88 3.4.21.88] </span></td></tr>
	[[3k2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA].		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k2z RCSB], [http://www.ebi.ac.uk/pdbsum/3k2z PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/3k2z_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Rice, P A.]]		[[Category: Rice, P A]]
	[[Category: Zhang, A P.P.]]		[[Category: Zhang, A P.P]]
	[[Category: Autocatalytic cleavage]]		[[Category: Autocatalytic cleavage]]
	[[Category: Dna damage]]		[[Category: Dna damage]]

OCA: Protected "3k2z" [edit=sysop:move=sysop]

2013-04-04T02:27:15Z

Protected "3k2z" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:27, 4 April 2013
(No difference)

OCA at 02:27, 4 April 2013

2013-04-04T02:27:13Z

← Older revision		Revision as of 02:27, 4 April 2013
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	~~{{Seed}}~~
	~~[[Image:3k2z.jpg\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3k2z", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3k2z\| PDB=3k2z \| SCENE= }}		{{STRUCTURE_3k2z\| PDB=3k2z \| SCENE= }}

	===Crystal structure of a LexA protein from Thermotoga maritima===		===Crystal structure of a LexA protein from Thermotoga maritima===

			==Function==
			[[http://www.uniprot.org/uniprot/LEXA_THEMA LEXA_THEMA]] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).

	==About this Structure==		==About this Structure==
	~~3K2Z~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA].		[[3k2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2Z OCA].
	[[Category: Repressor lexA]]		[[Category: Repressor lexA]]
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
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	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
	[[Category: Winged helix-turn-helix]]		[[Category: Winged helix-turn-helix]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:04:28 2010''~~

OCA at 02:54, 6 October 2010

2010-10-06T02:54:58Z

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-'''Unreleased structure'''
+{{Seed}}
-The entry 3k2z is ON HOLD  until Paper Publication
+<!--
-Authors: Zhang, A.P.P., Rice, P.A.
+===Crystal structure of a LexA protein from Thermotoga maritima===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:50:28 2009''
+==About this Structure==

OCA at 16:50, 18 November 2009

2009-11-18T16:50:29Z

← Older revision		Revision as of 16:50, 18 November 2009
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	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3k2z is ON HOLD		The entry 3k2z is ON HOLD until Paper Publication

	Authors: Zhang, A.P.P., Rice, P.A.		Authors: Zhang, A.P.P., Rice, P.A.
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	Description: Crystal structure of a LexA protein from Thermotoga maritima		Description: Crystal structure of a LexA protein from Thermotoga maritima

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 14 10~~:07:22 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:50:28 2009''

OCA at 08:07, 14 October 2009

2009-10-14T08:07:22Z

← Older revision		Revision as of 08:07, 14 October 2009
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	The entry 3k2z is ON HOLD		The entry 3k2z is ON HOLD

	Authors: Zhang, A.P.P, Rice, P.A.		Authors: Zhang, A.P.P., Rice, P.A.

	Description: Crystal structure of a LexA protein from Thermotoga maritima		Description: Crystal structure of a LexA protein from Thermotoga maritima

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct ~~7 13~~:45:31 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:07:22 2009''