3k4e - Revision history

OCA at 08:08, 6 September 2023

2023-09-06T08:08:59Z

← Older revision		Revision as of 08:08, 6 September 2023
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	==Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A==		==Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A==
	<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3k4e' size='340' side='right'caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3k4e]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3K4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k4e]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K4E FirstGlance]. <br>
	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3k49\|3k49]]</td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax~~.~~cgi?mode=Info&srchmode=5~~&~~id=4932 ATCC 18824])~~</td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [https://pdbe.org/3k4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [https://www.ebi.ac.uk/pdbsum/3k4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k4e ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [~~http~~://pdbe.org/3k4e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3k4e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3k4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[~~[http~~://www.uniprot.org/uniprot/PUF3_YEAST PUF3_YEAST]] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation. Regulates mitochondrial biogenesis, motility and morphology.<ref>PMID:11101532</ref> <ref>PMID:15337848</ref> <ref>PMID:16355254</ref> <ref>PMID:16244132</ref> <ref>PMID:17210948</ref> <ref>PMID:18523582</ref> <ref>PMID:18094119</ref>		[https://www.uniprot.org/uniprot/PUF3_YEAST PUF3_YEAST] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation. Regulates mitochondrial biogenesis, motility and morphology.<ref>PMID:11101532</ref> <ref>PMID:15337848</ref> <ref>PMID:16355254</ref> <ref>PMID:16244132</ref> <ref>PMID:17210948</ref> <ref>PMID:18523582</ref> <ref>PMID:18094119</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Atcc 18824~~]]		[[Category: Large Structures]]
	[[Category: Hall~~, T M.T~~]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Krahn~~, J M~~]]		[[Category: Hall TMT]]
	[[Category: Stumpf~~, C R~~]]		[[Category: Krahn JM]]
	[[Category: Wickens, M]]		[[Category: Stumpf CR]]
	[[Category: Zhu, D]]		[[Category: Wickens M]]
	~~[[Category: Membrane]]~~		[[Category: Zhu D]]
	~~[[Category: Mitochondrial mrna]]~~
	~~[[Category: Mitochondrion]]~~
	~~[[Category: Mitochondrion outer membrane]]~~
	~~[[Category: Phosphoprotein]]~~
	~~[[Category: Puf3]]~~
	~~[[Category: Pumilio]]~~
	~~[[Category: Rna binding]]~~
	~~[[Category: Rna binding protein - rna complex]]~~
	~~[[Category: Rna-binding~~]]

OCA at 19:23, 24 January 2018

2018-01-24T19:23:07Z

← Older revision		Revision as of 19:23, 24 January 2018
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	==Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A==		==Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A==
	<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3k49\|3k49]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3k49\|3k49]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://pdbe.org/3k4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://pdbe.org/3k4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3k4e ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/3k4e_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/3k4e_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 37:		Line 38:
	[[Category: Stumpf, C R]]		[[Category: Stumpf, C R]]
	[[Category: Wickens, M]]		[[Category: Wickens, M]]
	[[Category: Zhu,D]]		[[Category: Zhu, D]]
	[[Category: Membrane]]		[[Category: Membrane]]
	[[Category: Mitochondrial mrna]]		[[Category: Mitochondrial mrna]]

OCA at 16:44, 9 February 2016

2016-02-09T16:44:08Z

← Older revision		Revision as of 16:44, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3k4e]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K4E FirstGlance]. <br>		<table><tr><td colspan='2'>[[3k4e]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K4E FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3k49\|3k49]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3k49\|3k49]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ~~Saccharomyces cerevisiae~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://pdbe.org/3k4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k4e ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3k4e" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Saccharomyces cerevisiae~~]]		[[Category: Atcc 18824]]
	[[Category: Hall, T M.T]]		[[Category: Hall, T M.T]]
	[[Category: Krahn, J M]]		[[Category: Krahn, J M]]

OCA at 08:08, 25 December 2014

2014-12-25T08:08:57Z

← Older revision		Revision as of 08:08, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/PUF3_YEAST PUF3_YEAST]] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation. Regulates mitochondrial biogenesis, motility and morphology.<ref>PMID:11101532</ref> <ref>PMID:15337848</ref> <ref>PMID:16355254</ref> <ref>PMID:16244132</ref> <ref>PMID:17210948</ref> <ref>PMID:18523582</ref> <ref>PMID:18094119</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:48, 18 December 2014

2014-12-18T16:48:58Z

← Older revision		Revision as of 16:48, 18 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_3k4e\| PDB=3k4e \| SCENE= }}~~		==Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A==
	===Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A===		<StructureSection load='3k4e' size='340' side='right' caption='[[3k4e]], [[Resolution\|resolution]] 3.20Å' scene=''>
	~~{{ABSTRACT_PUBMED_19918084}}~~		== Structural highlights ==
			<table><tr><td colspan='2'>[[3k4e]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3K4E FirstGlance]. <br>
			</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3k49\|3k49]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L1325, PUF3, YLL013C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k4e OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k4e RCSB], [http://www.ebi.ac.uk/pdbsum/3k4e PDBsum]</span></td></tr>
			</table>
			== Evolutionary Conservation ==
			[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/3k4e_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			A single regulatory protein can control the fate of many mRNAs with related functions. The Puf3 protein of Saccharomyces cerevisiae is exemplary, as it binds and regulates more than 100 mRNAs that encode proteins with mitochondrial function. Here we elucidate the structural basis of that specificity. To do so, we explore the crystal structures of Puf3p complexes with 2 cognate RNAs. The key determinant of Puf3p specificity is an unusual interaction between a distinctive pocket of the protein with an RNA base outside the "core" PUF-binding site. That interaction dramatically affects binding affinity in vitro and is required for regulation in vivo. The Puf3p structures, combined with those of Puf4p in the same organism, illuminate the structural basis of natural PUF-RNA networks. Yeast Puf3p binds its own RNAs because they possess a -2C and is excluded from those of Puf4p which contain an additional nucleotide in the core-binding site.

	~~==Function==~~		A 5' cytosine binding pocket in Puf3p specifies regulation of mitochondrial mRNAs.,Zhu D, Stumpf CR, Krahn JM, Wickens M, Hall TM Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20192-7. Epub 2009 Nov 16. PMID:19918084<ref>PMID:19918084</ref>
	~~[[http://www.uniprot.org/uniprot/PUF3_YEAST PUF3_YEAST]] RNA-~~binding ~~protein involved~~ in ~~post-transcriptional~~ regulation~~. Negatively regulates expression~~ of ~~COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to~~ mRNAs ~~encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation~~. ~~Regulates mitochondrial biogenesis~~, ~~motility and morphology~~.~~<ref>PMID~~:~~11101532</ref> <ref>~~PMID:~~15337848</ref> <ref>PMID:16355254</ref> <ref>PMID:16244132</ref> <ref>PMID:17210948</ref> <ref>PMID:18523582</ref>~~ <ref>PMID:~~18094119~~</ref>

	~~==About this Structure==~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	~~[[3k4e]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA].~~		</div>
			== References ==
	==~~Reference~~==		<references/>
	~~<ref group="xtra">PMID:019918084</ref>~~<references ~~group="xtra"~~/><~~references~~/>		__TOC__
			</StructureSection>
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Hall, T M.T]]		[[Category: Hall, T M.T]]
	[[Category: Krahn, J M.]]		[[Category: Krahn, J M]]
	[[Category: Stumpf, C R.]]		[[Category: Stumpf, C R]]
	[[Category: Wickens, M.]]		[[Category: Wickens, M]]
	[[Category: Zhu,D.]]		[[Category: Zhu,D]]
	[[Category: Membrane]]		[[Category: Membrane]]
	[[Category: Mitochondrial mrna]]		[[Category: Mitochondrial mrna]]

OCA at 02:31, 4 April 2013

2013-04-04T02:31:41Z

@@ Line 1: / Line 1: @@
 {{STRUCTURE_3k4e|  PDB=3k4e  |  SCENE=  }}
 ===Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A===
+==Function==
-<!--
+[[http://www.uniprot.org/uniprot/PUF3_YEAST PUF3_YEAST]] RNA-binding protein involved in post-transcriptional regulation. Negatively regulates expression of COX17 by binding to the 3'-UTR of COX17 mRNA. Promotes decay of COX17 mRNA by enhancing its rate of deadenylation and subsequent turnover. Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation. Regulates mitochondrial biogenesis, motility and morphology.<ref>PMID:11101532</ref> <ref>PMID:15337848</ref> <ref>PMID:16355254</ref> <ref>PMID:16244132</ref> <ref>PMID:17210948</ref> <ref>PMID:18523582</ref> <ref>PMID:18094119</ref>
 ==About this Structure==
@@ Line 22: / Line 10: @@
 ==Reference==
-<ref group="xtra">PMID:19918084</ref><references group="xtra"/>
+<ref group="xtra">PMID:019918084</ref><references group="xtra"/><references/>
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Hall, T M.T]]
@@ Line 29: / Line 17: @@
 [[Category: Wickens, M.]]
 [[Category: Zhu,D.]]

OCA: Protected "3k4e" [edit=sysop:move=sysop]

2011-02-09T05:31:26Z

Protected "3k4e" [edit=sysop:move=sysop]

← Older revision	Revision as of 05:31, 9 February 2011
(No difference)

OCA at 05:31, 9 February 2011

2011-02-09T05:31:24Z

@@ Line 1: / Line 1: @@
 [[Image:3k4e.png|left|200px]]
@@ Line 12: / Line 11: @@
 ===Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A===
 ==About this Structure==
-K4E is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA].
+[[3k4e]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA].
 [[Category: Saccharomyces cerevisiae]]
 [[Category: Hall, T M.T]]
@@ Line 21: / Line 29: @@
 [[Category: Wickens, M.]]
 [[Category: Zhu,D.]]

OCA at 12:55, 28 January 2010

2010-01-28T12:55:43Z

← Older revision		Revision as of 12:55, 28 January 2010
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	{{Seed}}		{{Seed}}
	[[Image:3k4e.~~jpg~~\|left\|200px]]		[[Image:3k4e.png\|left\|200px]]

	<!--		<!--
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	==About this Structure==		==About this Structure==
	3K4E is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA].		3K4E is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K4E OCA].
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
	[[Category: Hall, T M.T]]		[[Category: Hall, T M.T]]
Line 33:		Line 33:
	[[Category: Rna-binding]]		[[Category: Rna-binding]]

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct~~ 28 14:03:~~36 2009~~''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:55:42 2010''

OCA at 12:03, 28 October 2009

2009-10-28T12:03:38Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3k4e is ON HOLD
+<!--
-Authors: Zhu,D., Stumpf, C.R., Krahn, J.M., Wickens, M., Hall, T.M.T
+===Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site A===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 14 10:07:51 2009''
+==About this Structure==