3klj - Revision history

OCA at 02:01, 21 November 2024

2024-11-21T02:01:50Z

← Older revision		Revision as of 02:01, 21 November 2024
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	==Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum==		==Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum==
	<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3klj' size='340' side='right'caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3klj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"clostridium_acetobutyricum"_prevot_1940 "clostridium acetobutyricum" prevot 1940~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3KLJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3klj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KLJ FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=FAD:FLAVIN~~-~~ADENINE+DINUCLEOTIDE'>FAD</scene>~~</td></tr>		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1488~~ "~~Clostridium acetobutyricum~~" ~~Prevot 1940])</td~~><~~/tr>~~		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1]~~ </~~span~~></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [https://pdbe.org/3klj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [https://www.ebi.ac.uk/pdbsum/3klj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3klj ProSAT]</span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [~~http~~://pdbe.org/3klj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3klj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3klj ProSAT]</span></td></tr>
	</table>		</table>
	~~== Function ==~~
	[[http://www.uniprot.org/uniprot/NROR_CLOAB NROR_CLOAB]] Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.<ref>PMID:11444870</ref> <ref>PMID:19084524</ref> <ref>PMID:19118342</ref> <ref>PMID:19124587</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3klj_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3klj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/~~initialview01~~.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3klj ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3klj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	~~== References ==~~
	~~<references/>~~
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Clostridium ~~acetobutyricum prevot 1940~~]]		[[Category: Clostridium acetobutylicum]]
	[[Category: Higuchi, Y]]		[[Category: Large Structures]]
	[[Category: Kawasaki, S]]		[[Category: Higuchi Y]]
	[[Category: Niimura, Y]]		[[Category: Kawasaki S]]
	[[Category: Nishikawa, K]]		[[Category: Niimura Y]]
	[[Category: Shomura, Y]]		[[Category: Nishikawa K]]
	~~[[Category: Fad-binding protein]]~~		[[Category: Shomura Y]]
	~~[[Category: Gr-fold]]~~
	~~[[Category: Oxidoreductase~~]]

OCA at 09:21, 26 December 2018

2018-12-26T09:21:51Z

← Older revision		Revision as of 09:21, 26 December 2018
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	==Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum==		==Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum==
	<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>
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	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 "Clostridium acetobutyricum" Prevot 1940])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 "Clostridium acetobutyricum" Prevot 1940])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://pdbe.org/3klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://pdbe.org/3klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3klj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3klj_consurf.spt"</scriptWhenChecked>		<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3klj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 04:36, 9 February 2016

2016-02-09T04:36:24Z

← Older revision		Revision as of 04:36, 9 February 2016
Line 2:		Line 2:
	<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3klj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Clostridium_acetobutylicum Clostridium acetobutylicum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KLJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3klj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"clostridium_acetobutyricum"_prevot_1940 "clostridium acetobutyricum" prevot 1940]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KLJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 Clostridium ~~acetobutylicum~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 "Clostridium acetobutyricum" Prevot 1940])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://pdbe.org/3klj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/~~Q9AL95_CLOAB Q9AL95_CLOAB~~]] Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.<ref>PMID:11444870</ref> <ref>PMID:~~19124587~~</ref> <ref>PMID:~~19084524~~</ref> <ref>PMID:~~19118342~~</ref>		[[http://www.uniprot.org/uniprot/NROR_CLOAB NROR_CLOAB]] Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.<ref>PMID:11444870</ref> <ref>PMID:19084524</ref> <ref>PMID:19118342</ref> <ref>PMID:19124587</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3klj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	== References ==		== References ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Clostridium ~~acetobutylicum~~]]		[[Category: Clostridium acetobutyricum prevot 1940]]
	[[Category: Higuchi, Y]]		[[Category: Higuchi, Y]]
	[[Category: Kawasaki, S]]		[[Category: Kawasaki, S]]

OCA at 04:27, 25 December 2014

2014-12-25T04:27:54Z

← Older revision		Revision as of 04:27, 25 December 2014
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>
	</table>		</table>
			== Function ==
			[[http://www.uniprot.org/uniprot/Q9AL95_CLOAB Q9AL95_CLOAB]] Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.<ref>PMID:11444870</ref> <ref>PMID:19124587</ref> <ref>PMID:19084524</ref> <ref>PMID:19118342</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
			== References ==
			<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:42, 18 December 2014

2014-12-18T17:42:17Z

← Older revision		Revision as of 17:42, 18 December 2014
Line 1:		Line 1:
	~~{{STRUCTURE_3klj\| PDB=3klj \| SCENE= }}~~		==Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum==
	===Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum===		<StructureSection load='3klj' size='340' side='right' caption='[[3klj]], [[Resolution\|resolution]] 2.10Å' scene=''>
			== Structural highlights ==
	==~~Function~~==		<table><tr><td colspan='2'>[[3klj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KLJ FirstGlance]. <br>
	[[http://~~www~~.~~uniprot~~.org/~~uniprot~~/~~Q9AL95_CLOAB Q9AL95_CLOAB]~~] ~~Catalyzes the NADH-dependent reduction of rubredoxin (Rd)~~. ~~NADPH~~ is ~~a very poor electron donor compared to NADH~~. ~~Functions as an intermediate component in the electron transfer chain: NADH~~->~~NROR-~~>~~Rd->FprA1~~/2. ~~Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx~~. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.~~acetobutylicum, an obligate anaerobic bacterium~~.<~~ref~~>~~PMID~~:~~11444870~~</~~ref~~> <~~ref~~>~~PMID~~:~~19124587~~</~~ref~~> <~~ref~~>~~PMID~~:~~19084524~~</~~ref~~> <~~ref~~>~~PMID~~:~~19118342~~</~~ref~~>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nror, CA_C2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1488 Clostridium acetobutylicum])</td></tr>
	==~~About this Structure~~==		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Rubredoxin--NAD(+)_reductase Rubredoxin--NAD(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.1 1.18.1.1] </span></td></tr>
	~~[[3klj]] is a 1 chain structure with sequence from~~ [http://en.wikipedia.org/wiki/~~Clostridium_acetobutylicum Clostridium acetobutylicum~~]. ~~Full crystallographic information is available from~~ [http://oca.weizmann.ac.il/oca-bin/~~ocashort~~?id=~~3KLJ~~ OCA].		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3klj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3klj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3klj RCSB], [http://www.ebi.ac.uk/pdbsum/3klj PDBsum]</span></td></tr>
			</table>
	==~~Reference~~==		== Evolutionary Conservation ==
	<~~ref group~~="~~xtra~~">~~PMID:020017214~~</~~ref~~><~~references group~~="~~xtra~~"/><~~references~~/>		[[Image:Consurf_key_small.gif\|200px\|right]]
			Check<jmol>
			<jmolCheckbox>
			<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kl/3klj_consurf.spt"</scriptWhenChecked>
			<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
			<text>to colour the structure by Evolutionary Conservation</text>
			</jmolCheckbox>
			</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
			<div style="clear:both"></div>
			__TOC__
			</StructureSection>
	[[Category: Clostridium acetobutylicum]]		[[Category: Clostridium acetobutylicum]]
	[[Category: Higuchi, Y.]]		[[Category: Higuchi, Y]]
	[[Category: Kawasaki, S.]]		[[Category: Kawasaki, S]]
	[[Category: Niimura, Y.]]		[[Category: Niimura, Y]]
	[[Category: Nishikawa, K.]]		[[Category: Nishikawa, K]]
	[[Category: Shomura, Y.]]		[[Category: Shomura, Y]]
	[[Category: Fad-binding protein]]		[[Category: Fad-binding protein]]
	[[Category: Gr-fold]]		[[Category: Gr-fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA: Protected "3klj" [edit=sysop:move=sysop]

2013-04-04T02:02:02Z

Protected "3klj" [edit=sysop:move=sysop]

← Older revision	Revision as of 02:02, 4 April 2013
(No difference)

OCA at 02:01, 4 April 2013

2013-04-04T02:01:57Z

← Older revision		Revision as of 02:01, 4 April 2013
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	~~{{Seed}}~~
	~~[[Image:3klj.jpg\|left\|200px]]~~

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3klj", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3klj\| PDB=3klj \| SCENE= }}		{{STRUCTURE_3klj\| PDB=3klj \| SCENE= }}

	===Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum===		===Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum===

			==Function==
			[[http://www.uniprot.org/uniprot/Q9AL95_CLOAB Q9AL95_CLOAB]] Catalyzes the NADH-dependent reduction of rubredoxin (Rd). NADPH is a very poor electron donor compared to NADH. Functions as an intermediate component in the electron transfer chain: NADH->NROR->Rd->FprA1/2. Also functions as an intermediate component in the electron transfer chains from NADH to revRbr and Dfx. Therefore, is a key electron carrier in an efficient multienzyme complex that can scavenge O(2) and reactive oxygen species (ROS), and thus plays an important role in the oxidative stress defense system in C.acetobutylicum, an obligate anaerobic bacterium.<ref>PMID:11444870</ref> <ref>PMID:19124587</ref> <ref>PMID:19084524</ref> <ref>PMID:19118342</ref>

	==About this Structure==		==About this Structure==
	~~3KLJ~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA].		[[3klj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_acetobutylicum Clostridium acetobutylicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KLJ OCA].

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20017214~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020017214</ref><references group="xtra"/><references/>
	[[Category: Clostridium acetobutylicum]]		[[Category: Clostridium acetobutylicum]]
	[[Category: Higuchi, Y.]]		[[Category: Higuchi, Y.]]
Line 27:		Line 19:
	[[Category: Gr-fold]]		[[Category: Gr-fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 17 10:21:10 2010''~~

OCA at 08:21, 17 February 2010

2010-02-17T08:21:11Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3klj is ON HOLD  until Paper Publication
+<!--
-Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y.
+===Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  2 09:38:27 2009''
+==About this Structure==

OCA at 07:38, 2 December 2009

2009-12-02T07:38:27Z

← Older revision		Revision as of 07:38, 2 December 2009
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

	The entry 3klj is ON HOLD		The entry 3klj is ON HOLD until Paper Publication

	Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y.		Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y.
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	Description: Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum		Description: Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum

	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 18 18~~:58:35 2009''		''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 2 09:38:27 2009''

OCA: New page: '''Unreleased structure''' The entry 3klj is ON HOLD Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y. Description: Crystal structure of NADH:rubredoxin oxido...

2009-11-18T16:58:36Z

New page: '''Unreleased structure''' The entry 3klj is ON HOLD Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y. Description: Crystal structure of NADH:rubredoxin oxido...

New page

'''Unreleased structure'''

The entry 3klj is ON HOLD

Authors: Nishikawa, K., Shomura, Y., Kawasaki, S., Niimura, Y., Higuchi, Y.

Description: Crystal structure of NADH:rubredoxin oxidoreductase from Clostridium acetobutylicum

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:58:35 2009''