3o08 - Revision history

OCA at 09:25, 6 September 2023

2023-09-06T09:25:05Z

← Older revision		Revision as of 09:25, 6 September 2023
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	<StructureSection load='3o08' size='340' side='right'caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3o08' size='340' side='right'caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_56498 Atcc 56498~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O08 FirstGlance]. <br>
	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NHE:2-[N~~-~~CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~		</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</div>~~</td></tr>		<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>KLLA0D11352g, RAG5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~28985 ATCC 56498])</td~~><~~/tr>~~
	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1]~~ </~~span~~></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [https://pdbe.org/3o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [https://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [https://pdbe.org/3o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [https://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>
	</table>		</table>
			== Function ==
			[https://www.uniprot.org/uniprot/HXK_KLULA HXK_KLULA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Atcc 56498]]~~		[[Category: Kluyveromyces lactis]]
	~~[[Category: Hexokinase~~]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Keim, A]]		[[Category: Keim A]]
	[[Category: Kettner, K]]		[[Category: Kettner K]]
	[[Category: Kriegel~~, T M~~]]		[[Category: Kriegel TM]]
	[[Category: Kuettner~~, E B~~]]		[[Category: Kuettner EB]]
	[[Category: Strater, N]]		[[Category: Strater N]]
	~~[[Category: Atp binding]]~~
	~~[[Category: Glucose repression]]~~
	~~[[Category: Glycolysis]]~~
	~~[[Category: Mig1 binding]]~~
	~~[[Category: Rnaseh-like fold]]~~
	~~[[Category: Transferase~~]]

OCA at 07:12, 12 May 2022

2022-05-12T07:12:49Z

← Older revision		Revision as of 07:12, 12 May 2022
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	==Crystal structure of dimeric KlHxk1 in crystal form I==		==Crystal structure of dimeric KlHxk1 in crystal form I==
	<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3o08' size='340' side='right'caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [~~http~~://pdbe.org/3o08 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [https://pdbe.org/3o08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [https://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 3o08" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3o08" style="background-color:#fffaf0;"></div>

			==See Also==
			*[[Hexokinase 3D structures\|Hexokinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	[[Category: Atcc 56498]]		[[Category: Atcc 56498]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
			[[Category: Large Structures]]
	[[Category: Keim, A]]		[[Category: Keim, A]]
	[[Category: Kettner, K]]		[[Category: Kettner, K]]

OCA at 19:28, 24 January 2018

2018-01-24T19:28:15Z

← Older revision		Revision as of 19:28, 24 January 2018
Line 3:		Line 3:
	<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Candida_sphaerica Candida sphaerica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ~~Candida sphaerica~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [http://pdbe.org/3o08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [http://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [http://pdbe.org/3o08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [http://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>
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	</div>		</div>
	<div class="pdbe-citations 3o08" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3o08" style="background-color:#fffaf0;"></div>

	~~==See Also==~~
	*[[Hexokinase\|Hexokinase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: ~~Candida sphaerica~~]]		[[Category: Atcc 56498]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Keim, A]]		[[Category: Keim, A]]

OCA at 03:56, 10 December 2016

2016-12-10T03:56:53Z

← Older revision		Revision as of 03:56, 10 December 2016
Line 1:		Line 1:

	==Crystal structure of dimeric KlHxk1 in crystal form I==		==Crystal structure of dimeric KlHxk1 in crystal form I==
	<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Kluyveromyces_lactis Kluyveromyces lactis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O08 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_sphaerica Candida sphaerica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O08 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ~~Kluyveromyces lactis~~])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 Candida sphaerica])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [http://www.ebi.ac.uk/pdbsum/3o08 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [http://pdbe.org/3o08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [http://www.ebi.ac.uk/pdbsum/3o08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o08 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
			<div class="pdbe-citations 3o08" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
			[[Category: Candida sphaerica]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	~~[[Category: Kluyveromyces lactis]]~~
	[[Category: Keim, A]]		[[Category: Keim, A]]
	[[Category: Kettner, K]]		[[Category: Kettner, K]]

OCA at 12:38, 9 December 2014

2014-12-09T12:38:03Z

← Older revision		Revision as of 12:38, 9 December 2014
Line 1:		Line 1:
	[[~~Image~~:~~3o08~~.~~png~~\|~~left~~\|~~200px~~]]		==Crystal structure of dimeric KlHxk1 in crystal form I==
			<StructureSection load='3o08' size='340' side='right' caption='[[3o08]], [[Resolution\|resolution]] 2.00Å' scene=''>
			== Structural highlights ==
			<table><tr><td colspan='2'>[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O08 FirstGlance]. <br>
			</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
			<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o6w\|3o6w]], [[3o8m\|3o8m]]</td></tr>
			<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 Kluyveromyces lactis])</td></tr>
			<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
			<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o08 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o08 RCSB], [http://www.ebi.ac.uk/pdbsum/3o08 PDBsum]</span></td></tr>
			</table>
			<div style="background-color:#fffaf0;">
			== Publication Abstract from PubMed ==
			Crystal structures of the unique hexokinase KlHxk1 of the yeast Kluyveromyces lactis were determined using eight independent crystal forms. In five crystal forms, a symmetrical ring-shaped homodimer was observed, corresponding to the physiological dimer existing in solution as shown by small-angle x-ray scattering. The dimer has a head-to-tail arrangement such that the small domain of one subunit interacts with the large domain of the other subunit. Dimer formation requires favorable interactions of the 15 N-terminal amino acids that are part of the large domain with amino acids of the small domain of the opposite subunit, respectively. The head-to-tail arrangement involving both domains of the two KlHxk1 subunits is appropriate to explain the reduced activity of the homodimer as compared with the monomeric enzyme and the influence of substrates and products on dimer formation and dissociation. In particular, the structure of the symmetrical KlHxk1 dimer serves to explain why phosphorylation of conserved residue Ser-15 may cause electrostatic repulsions with nearby negatively charged residues of the adjacent subunit, thereby inducing a dissociation of the homologous dimeric hexokinases KlHxk1 and ScHxk2. Two complex structures of KlHxk1 with bound glucose provide a molecular model of substrate binding to the open conformation and the subsequent classical domain closure motion of yeast hexokinases. The entirety of the novel data extends the current concept of glucose signaling in yeast and complements the induced-fit model by integrating the events of N-terminal phosphorylation and dissociation of homodimeric yeast hexokinases.

	~~{{STRUCTURE_3o08\| PDB=3o08 \| SCENE= }}~~		Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.,Kuettner EB, Kettner K, Keim A, Svergun DI, Volke D, Singer D, Hoffmann R, Muller EC, Otto A, Kriegel TM, Strater N J Biol Chem. 2010 Dec 24;285(52):41019-33. Epub 2010 Oct 12. PMID:20943665<ref>PMID:20943665</ref>

	~~===Crystal structure~~ of ~~dimeric KlHxk1 in crystal form I===~~		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
			</div>
	~~{{ABSTRACT_PUBMED_20943665}}~~

	~~==About this Structure==~~
	~~[[3o08]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]~~. ~~Full crystallographic information is available from [http://oca.weizmann.ac.il~~/~~oca-bin/ocashort?id=3O08 OCA].~~

	==See Also==		==See Also==
	*[[Hexokinase\|Hexokinase]]		*[[Hexokinase\|Hexokinase]]
			== References ==
	==~~Reference~~==		<references/>
	<~~ref group="xtra">PMID:020943665<~~/~~ref~~><~~references group="xtra"~~/>		__TOC__
			</StructureSection>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]
	[[Category: Keim, A.]]		[[Category: Keim, A]]
	[[Category: Kettner, K.]]		[[Category: Kettner, K]]
	[[Category: Kriegel, T M.]]		[[Category: Kriegel, T M]]
	[[Category: Kuettner, E B.]]		[[Category: Kuettner, E B]]
	[[Category: Strater, N.]]		[[Category: Strater, N]]
	[[Category: Atp binding]]		[[Category: Atp binding]]
	[[Category: Glucose repression]]		[[Category: Glucose repression]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
	~~[[Category: Hexokinase]]~~
	[[Category: Mig1 binding]]		[[Category: Mig1 binding]]
	[[Category: Rnaseh-like fold]]		[[Category: Rnaseh-like fold]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 05:33, 20 October 2012

2012-10-20T05:33:42Z

← Older revision		Revision as of 05:33, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
	[[3o08]] is a 2 chain structure ~~of [[Hexokinase]]~~ with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].		[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].

	==See Also==		==See Also==

OCA at 10:27, 25 July 2012

2012-07-25T10:27:49Z

← Older revision		Revision as of 10:27, 25 July 2012
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	[[Image:3o08.png\|left\|200px]]		[[Image:3o08.png\|left\|200px]]

	~~<!--~~
	~~The line below this paragraph, containing "STRUCTURE_3o08", creates the "Structure Box" on the page.~~
	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~
	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~
	~~or leave the SCENE parameter empty for the default display.~~
	~~-->~~
	{{STRUCTURE_3o08\| PDB=3o08 \| SCENE= }}		{{STRUCTURE_3o08\| PDB=3o08 \| SCENE= }}

	===Crystal structure of dimeric KlHxk1 in crystal form I===		===Crystal structure of dimeric KlHxk1 in crystal form I===


	~~<!--~~
	~~The line below this paragraph, {{ABSTRACT_PUBMED_20943665}}, adds the Publication Abstract to the page~~
	~~(as it appears on PubMed at http://www.pubmed.gov), where 20943665 is the PubMed ID number.~~
	~~-->~~
	{{ABSTRACT_PUBMED_20943665}}		{{ABSTRACT_PUBMED_20943665}}

	==About this Structure==		==About this Structure==
	[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].		[[3o08]] is a 2 chain structure of [[Hexokinase]] with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].

			==See Also==
			*[[Hexokinase\|Hexokinase]]

	==Reference==		==Reference==
	<ref group="xtra">PMID:~~20943665~~</ref><references group="xtra"/>		<ref group="xtra">PMID:020943665</ref><references group="xtra"/>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]

OCA: Protected "3o08" [edit=sysop:move=sysop]

2010-12-29T17:56:35Z

Protected "3o08" [edit=sysop:move=sysop]

← Older revision	Revision as of 17:56, 29 December 2010
(No difference)

OCA at 17:56, 29 December 2010

2010-12-29T17:56:34Z

← Older revision		Revision as of 17:56, 29 December 2010
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	~~{{Seed}}~~		[[Image:3o08.png\|left\|200px]]
	[[Image:3o08.~~jpg~~\|left\|200px]]

	<!--		<!--
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	===Crystal structure of dimeric KlHxk1 in crystal form I===		===Crystal structure of dimeric KlHxk1 in crystal form I===


			<!--
			The line below this paragraph, {{ABSTRACT_PUBMED_20943665}}, adds the Publication Abstract to the page
			(as it appears on PubMed at http://www.pubmed.gov), where 20943665 is the PubMed ID number.
			-->
			{{ABSTRACT_PUBMED_20943665}}

	==About this Structure==		==About this Structure==
	~~3O08~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].		[[3o08]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O08 OCA].

			==Reference==
			<ref group="xtra">PMID:20943665</ref><references group="xtra"/>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]
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	[[Category: Rnaseh-like fold]]		[[Category: Rnaseh-like fold]]
	[[Category: Transferase]]		[[Category: Transferase]]

	~~''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:49:29 2010''~~

OCA at 07:39, 13 October 2010

2010-10-13T07:39:41Z

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
-The entry 3o08 is ON HOLD  until Paper Publication
+<!--
-Authors: Kuettner, E.B., Kettner, K., Keim, A., Kriegel, T.M., Strater, N.
+===Crystal structure of dimeric KlHxk1 in crystal form I===
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:24:00 2010''
+==About this Structure==